Abstract:
:The local cutaneous inflammatory response to DMCB sensitization was positive in only 35% of 20 uremic patients, and the delayed skin reaction was positive in only 15%. The reaction to DMCB challenge was markedly delayed in some patients. Improved response to DNCB re-challenge followed levamisole administration in only 16% of the patients and was not associated with a rise in blood lymphocytes.
journal_name
Nephronjournal_title
Nephronauthors
Modai D,Sagi DB,Maor Jdoi
10.1159/000181858subject
Has Abstractpub_date
1980-01-01 00:00:00pages
280-2issue
6eissn
1660-8151issn
2235-3186journal_volume
25pub_type
杂志文章相关文献
NEPHRON文献大全abstract::The glomerular mesangium is an important site of activity in patients with heroin addiction. We studied the effect of morphine, a metabolite of heroin, on the mesangial immunoglobulin G aggregate uptake in a model of specific mesangial cell injury. Isolated specific mesangial cell injury was developed in Lewis rats by...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189301
更新日期:1996-01-01 00:00:00
abstract::A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000186805
更新日期:1992-01-01 00:00:00
abstract::Severe erythrocytosis is associated with increased whole blood viscosity and impaired blood flow. Since a reduced blood flow will cause tissue hypoxia and since tissue hypoxia is associated with increased synthesis of erythropoietin, erythrocytosis per se should cause an increase in the rate of red cell production. Th...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183585
更新日期:1985-01-01 00:00:00
abstract::Amyloid P component (AP) is a matrix glycoprotein of adult renal glomeruli. To establish whether the deposition of AP in glomeruli is an age-related phenomenon, this study used indirect immunofluorescence (IF) to investigate 34 renal biopsy specimens and 11 renal autopsy specimens. The biopsy specimens were taken from...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000190315
更新日期:1997-01-01 00:00:00
abstract::The function of renal allografts in patients who had received pretransplant immunoadsorption in order to remove cytotoxic anti-HLA antibodies was studied. We reviewed 6 patients who received a graft which functioned beyond 3 months; the mean follow-up period was 76 (range 62-89) months. Two grafts have been lost from ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000189281
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000507258
更新日期:2020-01-01 00:00:00
abstract::We describe two preparations for chronic peritoneal dialysis in the dog. In one group uremia was induced by nephrectomy and in the other by ureteral ligation. Peritoneal access was obtained using the Ash disc column catheter. Survival of the animals ranged from 27 to 83 days. Using a dialysis schedule similar in conce...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183093
更新日期:1983-01-01 00:00:00
abstract::We investigated the incidence of painless (silent) myocardial ischemia, manifested as S-T segment deviation, by Holter ECG monitoring in patients with chronic renal failure undergoing regular hemodialysis. Forty-five patients underwent Holter ECG monitoring for a continuous 48-hour period covering dialysis and the int...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186733
更新日期:1992-01-01 00:00:00
abstract::To investigate autonomic mechanisms underlying persistent hypotension in long-term hemodialysis patients, high-frequency (HF, > 0.15 Hz) and low-frequency (LF, 0.04-0.15 Hz) components of heart rate variability and plasma noradrenaline were analyzed in 10 persistently hypotensive hemodialysis patients (group H), 11 no...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188906
更新日期:1996-01-01 00:00:00
abstract::A patient with cadaveric renal transplantation was diagnosed by brain-computed tomography and ELISA as having neurocysticercosis in the CSF. Complete cure was achieved after praziquantel therapy. Function of the allograft was not affected. ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184074
更新日期:1987-01-01 00:00:00
abstract::Serum concentrations of soluble interleukin 2 receptor (IL-2R) were measured in 65 hemodialysis patients and compared with serum levels of beta 2-microglobulin and tissue polypeptide antigen (TPA). Elevated IL-2R levels, found in 85% of examined patients, correlated with elevated TPA serum concentrations (p less than ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186125
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To develop and internally validate a multivariable prediction model based on simple clinical record data and laboratory tests and to estimate the probability of left-ventricular diastolic dysfunction (LVDD) in stable maintenance hemodialysis (MHD) patients without clinical heart failure. DESIGN:Cross-section...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000499605
更新日期:2019-01-01 00:00:00
abstract::Human immunodeficiency virus (HIV) infection has been associated with several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) were also described in several patients with overt AIDS. We describe a patient who presented with HUS and only subsequent investigation to find the caus...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000188916
更新日期:1996-01-01 00:00:00
abstract::We studied the effects of mid-term enalapril administration on protein-load-induced renal responses in 10 patients with early chronic renal failure (serum creatinine 2.70 +/- 1.0 mg/dl). The oral protein load was performed twice, before and after a 10-day therapy with enalapril. Glomerular filtration rate (125I-iothal...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185624
更新日期:1989-01-01 00:00:00
abstract::Acute interstitial nephritis (AIN) has been reported in association with therapy with a number of drugs. We report a patient who developed drug-related AIN while receiving intravenous amoxicillin therapy. The patient developed rash, secondary temperature elevation, and eosinophilia in association with nonoliguric rena...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182077
更新日期:1981-01-01 00:00:00
abstract::We determined the clinical and immunopathological effects of dilazep hydrochloride (dilazep) on IgA nephropathy of ddY mice. Group I (early-treatment group, n = 10) was orally treated with 300 mg/kg body weight of this drug from 12 weeks of age until 60 weeks of age, and group II (late-treatment group, n = 10) was als...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045788
更新日期:2000-11-01 00:00:00
abstract::To test the hypothesis that acute angiotensin-converting enzyme (ACE) inhibition might predict the postoperative blood pressure outcome, a single oral dose of captopril ranging from 12.5 to 100 mg, was given to 26 patients with renovascular disease and its hypotensive effect was compared with that of surgery (21 patie...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184054
更新日期:1986-01-01 00:00:00
abstract::A long-term hemodialysis male patient was known to have systemic iron overload due to regular blood transfusions. As he was suspected to have aluminum overload, he received a single intravenous administration of desferrioxamine (that supported the hypothesis). Four days later, he became highly febrile with no focus of...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185208
更新日期:1988-01-01 00:00:00
abstract::To clarify the in vivo involvement of cellular adhesion molecules and cytokines in human glomerulonephritis, we have investigated the glomerular and interstitial expression of intercellular adhesion molecule 1 (ICAM-1) in 69 kidney biopsy specimens by immunohistochemical methods and its correlation with serum bioactiv...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000190225
更新日期:1997-01-01 00:00:00
abstract::136 patients on hemodialysis, 89 males and 47 females, were studied; we evaluated the index of hepatic function (SGOT and SGPT) and antibodies against HCV. We observed 42 cases of increased transaminases classified as non-A, non-B (NANB) hepatitis. Antibodies against HCV were present in 40 patients. Among 42 patients ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186903
更新日期:1992-01-01 00:00:00
abstract::This study sought to determine if low doses of ciclosporin (CS) designed to give fasting serum levels of 50-100 ng/ml achieve effective immunosuppression when used from the early postoperative period after renal transplantation. Ninety-four primary renal transplant recipients were studied. Group 1 patients were treate...
journal_title:Nephron
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000186007
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND/AIMS:Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the FAM20A gene result in amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000486607
更新日期:2018-01-01 00:00:00
abstract::The 24-hour urinary excretion of kallikrein (K) and prostaglandin E2 (PGE2), which reflects their intrarenal synthesis, was measured in 7 normal women (NW), 10 women with essential hypertension (EH), 26 normal pregnant women (NP), 12 women with hypertension in pregnancy (HP), and 4 women with toxemia. All pregnant wom...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183426
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Evidence indicates that hyperthermia preconditioning (HP) can be protective in kidney transplantation, possibly through increased heat shock protein (HSP) expression. A detailed study about individual HSPs and functional preservation is lacking, however. Therefore, we studied the effects of HP on kidney graf...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000054739
更新日期:2002-04-01 00:00:00
abstract::Sprague-Dawley rats given gentamicin from 10 to 70 mg/kg/day for 9 days showed a linear decrease in glomerular filtration rate with increasing dose, paralleled by histologic changes of acute tubular necrosis and cast formation only at the higher doses. Nephrotoxicity was correlated with the peak, rather than trough, s...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183023
更新日期:1983-01-01 00:00:00
abstract::Epidermal nevus syndrome is an unusual neurocutaneous disorder in which epidermal nevi are associated with abnormalities of the skeleton and central nervous system, including the eyes and somtimes the cardiovascular system. We treated a patient in whom the latter included renal artery stenosis. An 18-year-old man with...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045540
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Depression is the most common mental health disorder among those with end-stage renal disease (ESRD), with prevalence of 15-40%. However, the association between chronic kidney disease (CKD) and depression is more variable. We examined the associations of CKD with depression, perceived health status, and qua...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000455750
更新日期:2017-01-01 00:00:00
abstract::The effect of uremia upon the hepatic clearance rate of prednisone was studied in isolated perfused livers of normal and uremic female rats. The perfusion rate was kept at a constant flow rate of 25 ml/min. In order to induce uremia, one group of rats was 5/6 nephrectomized 3 weeks prior to the perfusions. The concent...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184072
更新日期:1987-01-01 00:00:00
abstract::In order to elucidate the mechanism of peritoneal dialysis fluid inhibition of cell functions, laboratory-prepared fluids were used to investigate the specific influences of low pH and high lactate concentration on neutrophil viability, phagocytosis, respiratory burst activation and leukotriene B4 (LTB4) generation. I...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187485
更新日期:1993-01-01 00:00:00
abstract::The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183053
更新日期:1983-01-01 00:00:00