Effects of a protein load in patients with early chronic renal failure before and after angiotensin II blockade.

abstract：:The physiologic action of prazosin in man was studied in 23 patients including 10 treated with prazosin plus polythiazide. Responders to prazosin alone (blood pressure fell greater than 10 mm Hg) had a decrease in peripheral resistance (p less than 0.02) and no significant change in plasma volume, while nonresponders'...

journal_title：Nephron

authors： Blaufox MD,Ross L,Koshy K,Lee HB

更新日期：1981-01-01 00:00:00

abstract：:The effect of isotonic mannitol and saline in the early phase of mercuric chloride-(HgCl2-)induced acute renal failure (ARF) in the dog was evaluated. During the first 3 h after HgCl2 alone, glomerular filtration rate (GFR) fell from 1.94 +/- 0.14 to 1.04 +/- 0.11 and renal blood flow (RBF) from 13.99 +/- 1.18 to 7.28...

journal_title：Nephron

authors： Vanholder R,Leusen I,Lameire N

更新日期：1984-01-01 00:00:00

abstract：:We measured levels of platelet-derived microparticles (PMP), which have coagulative activity and are produced by platelet activation or physical stimulation, and CD62P/CD63-positive platelets in patients with diabetes mellitus to determine their clinical significance and effects on complications of diabetes including ...

journal_title：Nephron

authors： Omoto S,Nomura S,Shouzu A,Hayakawa T,Shimizu H,Miyake Y,Yonemoto T,Nishikawa M,Fukuhara S,Inada M

更新日期：1999-01-01 00:00:00

abstract：:We found a strain of nonobese, nondiabetic (NON) mice which has spontaneous lipid deposition in glomerular capillary lumina. This strain was developed together with a diabetic strain of nonobese diabetic (NOD) mice for the generation of mouse models of diabetes mellitus. In the NON strain, contrary to the name, impair...

journal_title：Nephron

authors： Watanabe Y,Itoh Y,Yoshida F,Koh N,Tamai H,Fukatsu A,Matsuo S,Hotta N,Sakamoto N

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Sepsis and septic shock are life-threatening causes of acute kidney injury (AKI) frequently seen and managed in intensive care units (ICUs). Sepsis-associated AKI (SA-AKI) independently contributes to the mortality of sepsis. Understanding the potential factors involved in kidney function recovery may furthe...

journal_title：Nephron

authors： Chen JCY,Hu B,Frank RD,Kashani KB

更新日期：2020-01-01 00:00:00

abstract：:Previously, we have shown that insulin binding (IB) to erythrocytes was decreased in uremic patients and that hemodialysis corrected the receptor defect. In the present study cross-incubation experiments were performed using uremic and control erythrocytes and plasma. Incubation of control erythrocytes with uremic pla...

journal_title：Nephron

authors： Milutinović S,Breyer D,Janković N,Molnar V,Stefović A,Rocić B

更新日期：1983-01-01 00:00:00

abstract：:The biochemistry and function of vanadate and its possible role in health as well as in disease remains one of the most fascinating stories in biology. This review has surveyed the pertinent literature regarding its effect in the normal kidney and other tissues. While inhibition of the Na(+)-K+ ATPase enzyme was the f...

journal_title：Nephron

authors： Dafnis E,Sabatini S

更新日期：1994-01-01 00:00:00

abstract：:CBA/CaH-kdkd mice develop hereditary tubulointerstitial disease with mononuclear cell infiltration and cyst formation, possibly representing a model of human nephronophthisis. The purpose of the present investigation was to examine the components of the fibrotic changes which typically develop in the kidneys of these ...

journal_title：Nephron

authors： Sibalic V,Sun L,Sibalic A,Oertli B,Ritthaler T,Wüthrich RP

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND/AIM:The impact of dialysis membrane permeability on neutrophil transmigration properties in vitro was examined in the present study. This issue has not been fully scrutinized before. METHODS:We studied the capacity of neutrophils collected from a group of dialysis patients randomly treated with cuprophan, l...

journal_title：Nephron

authors： Moshfegh A,Jacobson SH,Halldén G,Thylén P,Lundahl J

更新日期：2002-08-01 00:00:00

abstract：:The concentration of ionic calcium (Ca2+ in the smooth muscular cells of the resistance vessels is a determining factor of their contraction. It depends on the influx of Ca2+ to the interior of the cells through the calcium channels in the sarcolemma. The effect of a specific Ca2+-channel blocking agent - nifedipine -...

journal_title：Nephron

authors： Moreira J,Barata JD,Olias J

更新日期：1985-01-01 00:00:00

abstract：:We determined the clinical and immunopathological effects of dilazep hydrochloride (dilazep) on IgA nephropathy of ddY mice. Group I (early-treatment group, n = 10) was orally treated with 300 mg/kg body weight of this drug from 12 weeks of age until 60 weeks of age, and group II (late-treatment group, n = 10) was als...

journal_title：Nephron

authors： Hayashi T,Kaneko S,Thang NT,Shou I,Shirato I,Tomino Y

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The herbal medicine Sairei-to is efficacious in renal diseases where mesangial proliferation is a key event. We examined whether Sairei-to inhibits proliferation of cultured rat mesangial cells and investigated its mechanism of action. METHODS:The effect of Sairei-to on [(3)H]-thymidine incorporation stimul...

journal_title：Nephron

authors： Awazu M,Fujita H,Omori S,Hida M

更新日期：2002-01-01 00:00:00

abstract：:The effects of a high-protein (HP) and low-protein (LP) meal on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and renal vascular resistance (RVR) were examined in conscious dogs. Ingestion of the HP and LP meal produced a temporary increase in systemic hemodynamic parameters due in part to a 'c...

journal_title：Nephron

authors： Zawada ET,Saelens DA,Alavi FK,Lembke JM

更新日期：1994-01-01 00:00:00

abstract：:Since 1987, we have experienced 11 children with acute renal failure (ARF) associated with Yersinia pseudotuberculosis (YP) infection. The illness began with the sudden onset of high fever, skin rash and gastrointestinal symptoms. Later in the course, periungual desquamation developed, mimicking Kawasaki disease. Elev...

journal_title：Nephron

authors： Cheong HI,Choi EH,Ha IS,Lee HJ,Choi Y

更新日期：1995-01-01 00:00:00

abstract：:Sickle cell nephropathy characterized by proteinuria and predominantly glomerular lesions has not been studied as extensively as renal tubular alterations in sickle cell disease. We reviewed our experience with this entity over a 14-year period. Of 13 children with either proteinuria or the nephrotic syndrome, 8 showe...

journal_title：Nephron

authors： Tejani A,Phadke K,Adamson O,Nicastri A,Chen CK,Sen D

更新日期：1985-01-01 00:00:00

abstract：:The effect of treatment with 1 alpha-hydroxycholecalciferol (1 alpha-OH-D3) and different diets on uremic arterial disease was studied. Three groups of rabbits with chronic renal failure (CRF) were kept on three diets with a low, medium or high content of calcium and phosphate. Half the rabbits in each group were trea...

journal_title：Nephron

authors： Tvedegaard E,Ladefoged O,Nielsen M,Kamstrup O

更新日期：1983-01-01 00:00:00

abstract：:Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...

journal_title：Nephron

authors： David-Walek T,Niederstadt C,Rob PM,Fricke L,Latta K,Steinhoff J,Stange EF

更新日期：2001-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：INTRODUCTION:Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) reduce proteinuria and slow renal disease progression more effectively than other therapies in patients with chronic kidney disease (CKD). However, differences regarding efficacy and safety between these therapies rem...

journal_title：Nephron

authors： Silvariño R,Rios P,Baldovinos G,Chichet MA,Perg N,Sola L,Saona G,De Souza N,Lamadrid V,Gadola L

更新日期：2019-01-01 00:00:00

abstract：:Hypertension secondary to renal transplantation was studied in our experimental model in the rat. In this model an intravenous injection of donor strain blood into recipients of allogeneic donor kidneys prior to transplantation was used to prolong the allograft survival. A reduced renal function associated with the hy...

journal_title：Nephron

authors： de Keijzer MH,Provoost AP,van Aken M,Kort WJ,Wolff ED,Molenaar JC

更新日期：1985-01-01 00:00:00

abstract：:Serum ferritin level has been shown by many investigators to be a good indicator of bone marrow iron stores in normal subjects. Although this correlation may hold in some pathological situations, it is lost in others. In leukemia a dissociation has been observed between serum ferritin levels and bone marrow iron store...

journal_title：Nephron

authors： Nuwayri-Salti N,Jabre F,Saab G,Daouk M,Salem Z

更新日期：1991-01-01 00:00:00

abstract：:15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and p...

journal_title：Nephron

authors： Oh MS,Carroll HJ

更新日期：1978-01-01 00:00:00

abstract：INTRODUCTION:In an attempt to decrease mortality in patients with end-stage renal disease, an increase in the lifetime of these patients without much focus on health-related quality of life (HRQOL) was pursued for a long period of time. However, lately, an improvement in the quality of this extended lifetime has focuse...

journal_title：Nephron

authors： Grincenkov FR,Fernandes N,Pereira Bdos S,Bastos K,Lopes AA,Finkelstein FO,Pecoits-Filho R,Qureshi AR,Divino-Filho JC,Bastos MG

更新日期：2015-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：:We have previously reported that hyperoxalemia can be aggravated by vitamin C supplementation in regular hemodialysis patients. The present study was undertaken to examine the validity of this observation in an experimental setting. Fifty five-sixths nephrectomized rats were divided into two groups: 30 rats were allow...

journal_title：Nephron

authors： Ono K,Ono H,Ono T,Kikawa K,Oh Y

更新日期：1989-01-01 00:00:00

abstract：:Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

journal_title：Nephron

authors： Kirschbaum BB

更新日期：1976-01-01 00:00:00

abstract：:Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but ...

journal_title：Nephron

authors： Carrara C,Abbate M,Sabadini E,Remuzzi G

更新日期：2017-01-01 00:00:00

abstract：:In kidney allografts, focal segmental glomerulosclerosis (FSGS) has been described as recurrent, de novo, or a histological variant of chronic transplant glomerulopathy. We describe a unique case of de novo FSGS in a renal transplant not accompanied by any feature of rejection in a patient who had not been immunosuppr...

journal_title：Nephron

authors： Trimarchi HM,Gonzalez JM,Truong LD,Brennan TS,Barrios R,Suki WN

更新日期：1999-01-01 00:00:00

abstract：:Parathyroidectomy was carried out in 26 patients over a 14-year period. Excellent results were obtained in patients with severe hyperparathyroidism. Vascular calcification, hypercalcaemia and pruritus did not justify surgery unless associated with unequivocal hyperparathyroidism. 13 patients required intravenous calci...

journal_title：Nephron

authors： Dawborn JK,Brown DJ,Douglas MC,Eddey HH,Heale WF,Thomas DP,Xipell JM

更新日期：1983-01-01 00:00:00

abstract：:Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission ...

journal_title：Nephron

authors： Nair RB,Date A,Kirubakaran MG,Shastry JC

更新日期：1987-01-01 00:00:00