Unique glomerular lesion with spontaneous lipid deposition in glomerular capillary lumina in the NON strain of mice.

abstract：:Using a 2-hour 47Ca absorption test, significant depression of active calcium absorption was demonstrated in 48 vitamin D untreated haemodialysis patients. This malabsorption of calcium could be corrected by the daily oral administration of 1--2 microgram of 1alphaOHD3 and 1--1.5 microgram of 1,25(OH)2D3. 5 microgram ...

journal_title：Nephron

authors： Pierides AM,Aljama P,Kerr DN,Scott M,Norman AW

更新日期：1978-01-01 00:00:00

abstract：:In order to estimate a regenerative response in the early phase after renal ischemia-reperfusion in rat, we examined the time course of the activation of epidermal growth factor receptor (EGFR) as a response of signal transduction pathway after 45 min ischemia in kidney. The activation of EGFR was observed 5-30 min af...

journal_title：Nephron

authors： Yano T,Yazima S,Hagiwara K,Ozasa H,Ishizuka S,Horikawa S

更新日期：1999-02-01 00:00:00

abstract：:Urate deposits within microtophi were found in 8% of unselected autopsies in Brisbane, Australia. Significant association were demonstrated with (a) a history of gouty arthritis and (b) the existence of nitrogen retention and renal disease of apparently primary, but not gouty, origin. However, in 26% of the patients, ...

journal_title：Nephron

authors： Linnane JW,Burry AF,Emmerson BT

更新日期：1981-01-01 00:00:00

abstract：:Hypokalemia and potassium depletion are frequent complications of amphotericin B therapy. Both ischemic and gentamicin-induced renal failure is potentiated by potassium depletion; it is, therefore, possible that amphotericin B nephrotoxicity is similarly influenced. This study evaluated whether the acute nephrotoxic r...

journal_title：Nephron

authors： Bernardo JF,Murakami S,Branch RA,Sabra R

更新日期：1995-01-01 00:00:00

abstract：:We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...

journal_title：Nephron

authors： Derbyshire ND,Asscher AW,Matthews PN

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The herbal medicine Sairei-to is efficacious in renal diseases where mesangial proliferation is a key event. We examined whether Sairei-to inhibits proliferation of cultured rat mesangial cells and investigated its mechanism of action. METHODS:The effect of Sairei-to on [(3)H]-thymidine incorporation stimul...

journal_title：Nephron

authors： Awazu M,Fujita H,Omori S,Hida M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND/AIM:Our previous study with prevalent cases suggested that some genetic, immunological and lifestyle-related factors increased the risk of immunoglobulin A nephropathy (IgAN). To confirm this hypothesis, we conducted another case-control study. METHODS:The study included 116 incident cases and 276 sex-, age...

journal_title：Nephron

authors： Wakai K,Nakai S,Matsuo S,Kawamura T,Hotta N,Maeda K,Ohno Y,Research Group on IgA Nephropathy.

更新日期：2002-01-01 00:00:00

abstract：:A 45-year-old male was admitted to the hospital because of polyuria and polydipsia. After admission, proteinuria and hematuria were found. The kidney function deteriorated and necessitated the initiation of chronic hemodialysis. Examination of the bone marrow revealed multiple myeloma and kappa light chains were found...

journal_title：Nephron

authors： Knobler H,Kopolovic J,Kleinman Y,Rubinger D,Silver J,Friedlaender MM,Popovtzer MM

更新日期：1983-01-01 00:00:00

abstract：:We examined the types of guanine nucleotide-binding regulatory (G) protein subunits in isolated glomeruli, cortices excluding glomeruli and medullas of rat kidneys using bacterial toxin-catalyzed adenosine 5'-diphosphate (ADP) ribosylation and specific immunoblots. ADP ribosylation catalyzed by cholera or pertussis to...

journal_title：Nephron

authors： Yanagisawa H,Kurihara N,Klahr S,Morrissey J,Wada O

更新日期：1994-01-01 00:00:00

abstract：:The role of renal hemodynamic alterations in the curtailment of renal functions was studied in uranyl acetate-induced oliguric (ORF) and nonoliguric (NORF) renal failures of rabbits. 5 days after drug injection, renal functional and morphological changes were most remarkable. A depression of Cin and elevation of serum...

journal_title：Nephron

authors： Sudo M,Honda N,Hishida A,Nagase M

更新日期：1980-01-01 00:00:00

abstract：:Although serologic studies have identified hantaviral infection in the United States, acute disease has not been recognized. This study describes 3 cases of domestically acquired hemorrhagic fever with renal syndrome (HFRS) in the United States. Infection was due to a local strain of Seoul virus (Baltimore rat virus)....

journal_title：Nephron

authors： Glass GE,Watson AJ,LeDuc JW,Childs JE

更新日期：1994-01-01 00:00:00

abstract：:A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism, presenting severe hyponatremia, is described. A 57-year-old man complaining of nausea, vomiting and fatigability was admitted to our hospital because of hyponatremia (114 mEq/I). The low levels of serum cortisol and urinary 17-OHCS suggested gluc...

journal_title：Nephron

authors： Okada K,Takahashi S

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The development of abnormalities in red blood cell (RBC) deformability in patients undergoing hemodialysis remains a major problem, because it is related to peripheral microcirculation, oxygen supply, and various complications in such patients. gamma-Linolenic acid (GLA; 18:3n-6), one of the polyunsaturated ...

journal_title：Nephron

authors： Iijima S,Otsuka F,Kikuchi H,Yamada K,Nakajima T,Yahiro K,Kondo A

更新日期：2000-10-01 00:00:00

abstract：:Fibrinogen fragments (X, Y, D and E) and fibrin fragments (D-dimer and E) were examined in the urine of 52 patients with various types of renal diseases. One or more of the fibrinogen fragments were detectable in all the urine specimens. D-Dimer together with fibrinogen fragments was found in 38 of the 52 patients. Th...

journal_title：Nephron

authors： Yoshioka K,Iseki T,Akano N,Uraoka Y,Miyata H,Maki S

更新日期：1982-01-01 00:00:00

abstract：:Deproteinized plasma from patients with renal failure had an inhibitory effect on Na,K ATPase activity measured in vitro by a linked-enzyme assay. No inhibitory effect was observed with plasma from normal subjects or from patients undergoing chronic ambulatory peritoneal dialysis. The inhibition of Na,K ATPase whether...

journal_title：Nephron

authors： Stokes GS,Norris LA,Marwood JF,Johnston H,Caterson RJ

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Diastolic dysfunction (DD) and low levels of thyroid hormones (TH) are frequent found in chronic kidney disease; both are associated with all-cause and cardiovascular mortality. However, a link between them has not yet been established. The aim of this study was to analyze DD as a surrogate marker of fi...

journal_title：Nephron

authors： Sánchez V,Paniagua R,Prado MD,Mora C,Orihuela O,Martínez-Baca F,Pérez EE,Calzada C,Romero R,Avila M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Increased susceptibility of the kidney to acute renal failure (ARF) in the setting of sepsis even in the absence of systemic hypotension is well known. In the hypothesis that the proinflammatory cytokines and lipopolysaccharide (LPS) in gram-negative sepsis can directly cause renal tubular cell apoptosi...

journal_title：Nephron

authors： Jo SK,Cha DR,Cho WY,Kim HK,Chang KH,Yun SY,Won NH

更新日期：2002-07-01 00:00:00

abstract：:Previously, we have shown that insulin binding (IB) to erythrocytes was decreased in uremic patients and that hemodialysis corrected the receptor defect. In the present study cross-incubation experiments were performed using uremic and control erythrocytes and plasma. Incubation of control erythrocytes with uremic pla...

journal_title：Nephron

authors： Milutinović S,Breyer D,Janković N,Molnar V,Stefović A,Rocić B

更新日期：1983-01-01 00:00:00

abstract：:Differences have been postulated for the mechanism of natriuresis due to atrial natriuretic peptide (ANP), salt loading with high salt diet (HS) and acute volume expansion (AcVE), in particular between AcVE and ANP based on the observed synergism between the two. Therefore the effects of and the interaction between th...

journal_title：Nephron

authors： Reddy S,Salipan-Moore N,Mildenberger S,Willis N,Györy AZ

更新日期：1998-01-01 00:00:00

abstract：:Hemodialysis (HD) prescription is usually based on the periodical measurement of the Kt/V achieved in a midweek dialysis session. The purpose of the study was to assess the duration of each HD session to achieve a target dose of dialysis. This allowed to determine whether a given dialysis session may be considered rep...

journal_title：Nephron

authors： Hernandez-Herrera G,Martin-Malo A,Rodriguez M,Aljama P

更新日期：2001-09-01 00:00:00

abstract：:We studied the effects of mid-term enalapril administration on protein-load-induced renal responses in 10 patients with early chronic renal failure (serum creatinine 2.70 +/- 1.0 mg/dl). The oral protein load was performed twice, before and after a 10-day therapy with enalapril. Glomerular filtration rate (125I-iothal...

journal_title：Nephron

authors： Oldrizzi L,Rugiu C,Maschio G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:At present, the determination of dry weight in patients on hemodialysis is largely made empirically by trial and error. Extracellular volume (ECV) assessment by bioimpedance analysis (BIA) is a preferable technique for determining dry weight, and it also provides useful data on body composition. METHODS:We ...

journal_title：Nephron

authors： Chen YC,Chen HH,Yeh JC,Chen SY

更新日期：2002-09-01 00:00:00

abstract：:A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...

journal_title：Nephron

authors： Kelley WN

更新日期：1975-01-01 00:00:00

abstract：:In this study, we examined the hypothesis whether exogenous administration of L-lysine in drinking water would reduce nonenzymatic glycation of glomerular basement membrane (GBM) collagen and thus albuminuria in streptozotocin-diabetic rats. The rationale is that the administered lysine would combine with the circulat...

journal_title：Nephron

authors： Jyothirmayi GN,Modak R,Reddi AS

更新日期：2001-02-01 00:00:00

abstract：:The authors describe an unusual case of radial artery pseudoaneurysm in a patient with a Brescia-Cimino fistula. Evaluation of a pulsatile mass on the patient's forearm which occurred after hemodialysis led to a nondiagnostic fistulogram. Color flow ultrasound was helpful in identifying the nature of the abnormality, ...

journal_title：Nephron

authors： Labus TP,Trerotola SO,Savader SJ

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Several studies have provided convincing evidence that in apparently healthy subjects elevated serum levels of plasma C-reactive protein (CRP) are associated with an increased risk of experiencing myocardial infarction and sudden cardiac death. It has been claimed that, in dialytic patients, the hepatic synt...

journal_title：Nephron

authors： Panichi V,Migliori M,De Pietro S,Taccola D,Bianchi AM,Giovannini L,Norpoth M,Metelli MR,Cristofani R,Bertelli AA,Sbragia G,Tetta C,Palla R,Colombo R

更新日期：2002-08-01 00:00:00

abstract：:To avoid the use of aluminium as a phosphate binder, patients on CAPD who were stable were dialysed against a peritoneal dialysis fluid which was magnesium free. A mixture of calcium and magnesium carbonate was used as a phosphate binder over a period in excess of 1 year. Vitamin D analogues were used in the majority....

journal_title：Nephron

authors： Parsons V,Baldwin D,Moniz C,Marsden J,Ball E,Rifkin I

更新日期：1993-01-01 00:00:00

abstract：:Experiences with peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) program at a single center over 8 years were reviewed. Home-acquired peritonitis rates have been less than 1 episode per patient year since 1982. Gram-positive organisms continue to account for most episodes in a similar proportion. Act...

journal_title：Nephron

authors： Prowant B,Nolph K,Ryan L,Twardowski Z,Khanna R

更新日期：1986-01-01 00:00:00

abstract：:We have previously documented the importance of tumor necrosis factor (TNF) alpha in the pathogenesis of nephrotoxic-serum nephritis in rats. In this study, we evaluated the possible relevance of the well-established cytocidal TNF activity to the mechanism of glomerular injury by assessing sensitivity of rat mesangial...

journal_title：Nephron

authors： Hruby ZW,Cybulsky AV,Lowry RP

更新日期：1990-01-01 00:00:00

abstract：:Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...

journal_title：Nephron

authors： de Paoli Vitali E,Ricci G,Perini L,Malacarne F,Vedovato M,Guerra G,Dapporto M,Gilli P

更新日期：1996-01-01 00:00:00