High Prevalence of Diastolic Dysfunction in Incident Patients on Peritoneal Dialysis: Association with Low Thyroid Hormones.

abstract：:To clarify the reliability of urinary trehalase activity as a marker of cellular proliferation and/or damage of renal proximal tubules, the activity was examined in healthy newborn infants or infants treated with tobramycin, a drug known as causing tubular cell damage. Eighty-one newborn infants (56 mature infants and...

journal_title：Nephron

authors： Sasai-Takedatsu M,Kojima T,Taketani S,Ono A,Kitamura N,Kobayashi Y

更新日期：1995-01-01 00:00:00

abstract：:Previous reports on the nephritogenic and immunological enhancing capacity of posttransplant circulating immune complexes (CICs) are conflicting and have been confined to the study of acute rejection episode (AR). This study was undertaken to assess the nephritogenicity of CICs in patients undergoing accelerated acute...

journal_title：Nephron

authors： Jordan SC,Sakai R,Ettenger RB,Fine RN

更新日期：1982-01-01 00:00:00

abstract：:A gradual loss of cell viability was observed during in vitro incubation of peritoneal cells from chronically uremic mice in commercial peritoneal dialysis solutions. The magnitude of this cytotoxicity toward peritoneal cells harvested from uremic mice and controls was comparable. Resident peritoneal cells were always...

journal_title：Nephron

authors： Gallimore B,Gagnon RF,Stevenson MM

更新日期：1986-01-01 00:00:00

abstract：:We have previously documented the importance of tumor necrosis factor (TNF) alpha in the pathogenesis of nephrotoxic-serum nephritis in rats. In this study, we evaluated the possible relevance of the well-established cytocidal TNF activity to the mechanism of glomerular injury by assessing sensitivity of rat mesangial...

journal_title：Nephron

authors： Hruby ZW,Cybulsky AV,Lowry RP

更新日期：1990-01-01 00:00:00

abstract：:Urinary excretion of oxalate, calcium and urate has been investigated in 88 patients affected by idiopathic calcium oxalate stone disease and in 20 normal subjects. Of these ions, only oxalate was found significantly higher in stone formers. Defining hyperoxaluria as urinary oxalate excretion greater than 2 SD above n...

journal_title：Nephron

authors： Baggio B,Gambaro G,Favaro S,Borsatti A

更新日期：1983-01-01 00:00:00

abstract：CONTEXT:The widespread use of diuretics, potassium supplements, and medications that block renin angiotensin system puts the chronic kidney disease (CKD) population at high risk for dyskalemia, both hyperkalemia and hypokalemia. The optimal potassium level in a CKD patient is unknown. Subject of review: Two recent stud...

journal_title：Nephron

authors： Tandukar S,Fried LF

更新日期：2018-01-01 00:00:00

abstract：:The role of T cell-mediated immunity in the early phase of nephrotoxic serum nephritis (NTN) was examined by transfer of pan T, CD8-positive, and CD4-positive cells. The disease was induced by transferring rabbit gamma-globulin (RGG)-sensitized T cells to nude (rnu/rnu) rats pretreated with a subnephritogenic dose (a ...

journal_title：Nephron

authors： Kuroda T,Kawasaki K,Oite T,Arakawa M,Shimizu F

更新日期：1994-01-01 00:00:00

abstract：:The investigation of a sample of 99 women on maintenance hemodialysis has shown the presence of sexual disturbances to a great extent: the rate of sexual intercourse and the ability to reach orgasm were significantly lower than in age-matched control women. 80% declared a reduction in their sexual desire and the frequ...

journal_title：Nephron

authors： Mastrogiacomo I,De Besi L,Serafini E,Zussa S,Zucchetta P,Romagnoli GF,Saporiti E,Dean P,Ronco C,Adami A

更新日期：1984-01-01 00:00:00

abstract：:Previous work has shown that cigarette-smoking affects platelets and endothelium in men and women without renal failure. The present study compared 10 male habitual smokers receiving maintenance hemodialysis for chronic renal failure with 11 healthy male habitual smokers before and after controlled cigarette-smoking a...

journal_title：Nephron

authors： Davis JW,Arnold J,Wiegmann T

更新日期：1993-01-01 00:00:00

abstract：:Diseases affecting both the lung and the kidney have grave prognosis and serious diagnostic and therapeutic consequences. Here, 3 cases of pulmonary-renal syndrome caused by antiphospholipid syndrome are reported. The patients presented with dyspnea, renal insufficiency, pulmonary infiltrates on chest X-ray and areas ...

journal_title：Nephron

authors： Henning BF,Gröne HJ,Tepel M,Büchner N,Kirchner J,Zidek W

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) is a crucial event in the development of renal interstitial fibrosis (RIF). A growing body of evidence indicates that β-catenin plays an important role in various types of fibrosis. Although members of the microRNA (miRNA)-200 family have been suggested to suppress...

journal_title：Nephron

authors： Gong Y,Qin Z,Zhou B,Chen H,Shi Z,Zhang J

更新日期：2017-01-01 00:00:00

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:The local cutaneous inflammatory response to DMCB sensitization was positive in only 35% of 20 uremic patients, and the delayed skin reaction was positive in only 15%. The reaction to DMCB challenge was markedly delayed in some patients. Improved response to DNCB re-challenge followed levamisole administration in only...

journal_title：Nephron

authors： Modai D,Sagi DB,Maor J

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. METHODS:We performed an observational study on patients (≥18 years old) who had been on HD for ...

journal_title：Nephron

authors： Lim Y,Yang G,Cho S,Kim SR,Lee YJ

更新日期：2020-01-01 00:00:00

abstract：:A modified sieving technique has been developed to isolate pure glomeruli from monkey, sheep, dog, rabbit and rat kidney. Glomeruli from all these species have been grown in tissue culture and the glomerular cell outgrowth studied by light microscopy and time-lapse cinemicroscopy. The pattern of growth was the same fo...

journal_title：Nephron

authors： Holdsworth SR,Glasgow EF,Atkins RC,Thomson NM

更新日期：1978-01-01 00:00:00

abstract：:Patients with familial lecithin-cholesterol acyltransferase (LCAT) deficiency very often show progressive glomerulosclerosis with evolution to end-stage disease. High levels of an abnormal lipoprotein (lipoprotein X) cause glomerular capillary endothelial damage. The ultrastructural study of renal biopsy specimens sho...

journal_title：Nephron

authors： Sessa A,Battini G,Meroni M,Daidone G,Carnera I,Brambilla PL,Viganò G,Giordano F,Pallotti F,Torri Tarelli L,Calabresi L,Rolleri M,Bertolini S

更新日期：2001-07-01 00:00:00

abstract：:8 patients with thrombotic microangiopathy were treated with a new antithrombotic agent, defibrotide. This drug displays considerable fibrinolytic and antithrombotic activity, and induces generation and release of a prostacyclin-like substance from vascular tissue. At admission all patients presented severe renal invo...

journal_title：Nephron

authors： Bonomini V,Frascà GM,Raimondi C,Liviano D'arcangelo G,Vangelista A

更新日期：1985-01-01 00:00:00

abstract：:This study was undertaken to evaluate the relation between the urinary excretion of guanidinoacetic acid (GAA) and other substances in hypertensive patients (6 with borderline hypertension and 29 with hypertension) and 12 normal controls. In 10 of the hypertensive patients, GAA was measured before and after 4 weeks of...

journal_title：Nephron

authors： Takano Y,Aoike I,Gejyo F,Arakawa M

更新日期：1989-01-01 00:00:00

abstract：:Severe erythrocytosis is associated with increased whole blood viscosity and impaired blood flow. Since a reduced blood flow will cause tissue hypoxia and since tissue hypoxia is associated with increased synthesis of erythropoietin, erythrocytosis per se should cause an increase in the rate of red cell production. Th...

journal_title：Nephron

authors： Erslev AJ,Caro J,Besarab A

更新日期：1985-01-01 00:00:00

abstract：:The variations of ionized and total calcium concentrations were studied during haemodialysis with high flux membrane using dialysate calcium concentrations of 1.63 and 1.76 mmol/l. The changes in ionized and total calcium were related to the predialytic calcium concentration difference between plasma and dialysate. Th...

journal_title：Nephron

authors： Kancir CB,Wanscher M,Petersen PH

更新日期：1988-01-01 00:00:00

abstract：:It has been reported that calcium deposition and calcium content in cultured human aortic smooth muscle cells (SMC) increased when the cells are incubated in a medium with a high phosphate concentration (2 mM). To determine the cellular components or soluble factors contributing to the deposition, we cultured commerci...

journal_title：Nephron

authors： Watanabe Y,Suzuki M,Oyama Y,Kusano E,Tamba K,Iimura O,Ito C,Imai M,Asano Y

更新日期：2002-12-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) to undergo spontaneous and induced interleukin-1 (IL-1) production was examined in 10 healthy controls and in 10 patients undergoing intermittent hemodialysis (HD) using cuprophane membranes. Extracellular and cytoplasmic IL-1 activity was assayed by biologic a...

journal_title：Nephron

authors： Blumenstein M,Schmidt B,Ward RA,Ziegler-Heitbrock HW,Gurland HJ

更新日期：1988-01-01 00:00:00

abstract：:Changes in renal function and structure are frequently observed in patients with diabetes mellitus. In the early phases of the disease, alterations in glomerular filtration rate, renal plasma flow, glomerular permeability and tubular capacity for glucose reabsorption occur. In the late stages of juvenile onset diabete...

journal_title：Nephron

authors： Rubenstein AH,Mako ME,Horwitz DL

更新日期：1975-01-01 00:00:00

abstract：:Nephrotoxic agents such as puromycin aminonucleoside (PAN) and sodium maleate (MAL) have been used to induce experimental glomerular proteinuria and tubular disease, respectively. Current studies show that PAN caused a massive loss of albumin in the urine while not affecting the excretion of the smaller, sex-dependent...

journal_title：Nephron

authors： Neuhaus OW,Flory W,Biswas N,Hollerman CE

更新日期：1981-01-01 00:00:00

abstract：:Serial changes in plasma of renin concentration (PRC), renin-substrate concentration (PSC) and renin activity (PRA) were followed in rats during glycerol-induced acute renal failure. There was an early but transient increase in PRC and a more delayed and prolonged rise in PSC. PRA began to rise a few hours after glyce...

journal_title：Nephron

authors： Carvalho JS,Page LB

更新日期：1978-01-01 00:00:00

abstract：:Chromoblastomycosis is a rare, deep mycosis seen mostly in tropical and subtropical regions. We have encountered a kidney transplant recipient with this subcutaneous mycosis developing as an asymptomatic mass in the right forearm. The lesion recurred after an initial local excision, but it is now apparently cured 10 m...

journal_title：Nephron

authors： Morales LA,González ZA,Santiago-Delpín EA

更新日期：1985-01-01 00:00:00

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:Cytomegalovirus is the most important viral infection in kidney transplants, but rarely affects the allograft after the sixth month posttransplantation. We present a patient who developed renal failure eighteen months posttransplant; a kidney biopsy showed cytomegalovirus inclusions, acute tubular necrosis and mild in...

journal_title：Nephron

authors： Trimarchi H,Jordan R,Iotti A,Forrester M,Iotti R,Freixas E,Martínez J,Schropp J,Pereyra H,Efrón E

更新日期：2002-10-01 00:00:00

abstract：:In 2014 57.5% of HD patients and 62.7% of PD patients achieved the audit measure for phosphate. 29.0% of HD and 30.3% of PD patients had a serum phosphate above the audit standard range. 79.1% of HD and 79.7% of PD patients had adjusted calcium between 2.2–2.5 mmol/L. 57.4% of HD and 65.0% of PD patients had a serum P...

journal_title：Nephron

authors： Nicholas J,Evans R,Shaw C,Dawnay A

更新日期：2016-01-01 00:00:00

abstract：:Renal biopsy specimens obtained from patients with various chronic nephropathies were studied by immunofluorescence (IF), electron and light microscopy. Of 49 biopsies studied by IF, 22 had granular deposits of IgG and/or C3 along the basement membranes of proximal tubules while 14 had linear and 13 both linear and gr...

journal_title：Nephron

authors： Orfila C,Rakotoarivony J,Durand D,Suc JM

更新日期：1979-01-01 00:00:00