Cytotoxicity of commercial peritoneal dialysis solutions towards peritoneal cells of chronically uremic mice.

abstract：:Experiences with peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) program at a single center over 8 years were reviewed. Home-acquired peritonitis rates have been less than 1 episode per patient year since 1982. Gram-positive organisms continue to account for most episodes in a similar proportion. Act...

journal_title：Nephron

authors： Prowant B,Nolph K,Ryan L,Twardowski Z,Khanna R

更新日期：1986-01-01 00:00:00

abstract：:A 51-year-old man with diabetes mellitus and the nephrotic syndrome on renal biopsy was found to have diabetic glomerulosclerosis, amyloidosis and membranous glomerulopathy. The presence of three distinct glomerular diseases in the same patient is unique. Possible factors involved in their pathogenesis are discussed a...

journal_title：Nephron

authors： Bertani T,Olesnicky L,Abu-Regiaba S,Glasberg S,Pirani CL

更新日期：1983-01-01 00:00:00

abstract：:An 11-year-old boy developed Kaposi's sarcoma and progressive T lymphocyte deficiency 5 years after cadaveric kidney transplantation for end-stage renal disease. He had received 17 individual red blood cell transfusions prior to and during transplantation in 1980. Human immunodeficiency virus (HIV) was cultured from b...

journal_title：Nephron

authors： Malekzadeh MH,Church JA,Siegel SE,Mitchell WG,Opas L,Lieberman E

更新日期：1987-01-01 00:00:00

abstract：:Medullary sponge kidney was found in association with congenital absence of teeth (anodontia) in 3 siblings of a single family. Anodontia occurs in the rare familial syndrome of ectodermal dysplasia, but its association with a renal (mesodermal) anomaly is not known. The present report lends further support to a possi...

journal_title：Nephron

authors： Khoury Z,Brezis M,Mogle P

更新日期：1988-01-01 00:00:00

abstract：:Recent studies have revealed the potential importance of the extracellular matrix (ECM) in the modulation of mesangial cell (MC) function. Interleukin-6 (IL-6) is produced by MCs and was shown to induce MC proliferation, acting as an autocrine growth factor. Heparin is a known inhibitor of MC proliferation. It was sho...

journal_title：Nephron

authors： Benador NM,Girardin EP

更新日期：1997-01-01 00:00:00

abstract：:The effects of chronic ethanol ingestion on the rat kidney were studied. Rats were fed a liquid diet containing ethanol for 5 weeks to induce chronic alcoholism. Renal ischemia was introduced by clamping the renal artery and vein either for 10 or 20 min. The glomerular filtration rate (GFR) and the renal blood flow (R...

journal_title：Nephron

authors： Ishigami M,Ohnishi ST,Chan R,Shimada Y,Yabuki S

更新日期：1989-01-01 00:00:00

abstract：:A 64-year-old woman presenting with a history of increasing oedema was found to have nephrotic syndrome with a 24-hour urinary protein excretion of 20.7 g and renal impairment with an initial serum creatinine level of 197 mumol/l (2.16 mg/dl). A renal tumour was demonstrated by ultrasound scanning and subsequent nephr...

journal_title：Nephron

authors： Woodrow G,Innes A,Ansell ID,Burden RP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Anemia management in chronic hemodialysis (HD) has been affected by the implementation of the prospective payment system (PPS) and changes in clinical guidelines. These factors could impact red blood cell (RBC) transfusion in HD patients. Our distinctive care system contains complete records for all RBC tran...

journal_title：Nephron

authors： Albright RC Jr,Dillon JJ,Hocum CL,Stubbs JR,Johnson PM,Hickson LJ,Williams AW,Dingli D,McCarthy JT

更新日期：2016-01-01 00:00:00

abstract：:We measured peritoneal losses of the active vitamin D metabolites 1,25(OH)2D3 and 24,25(OH)2D3 in patients receiving continuous ambulatory peritoneal dialysis (CAPD). The serum concentration of 24,25(OH)2D3 was considerably lower than in hemodialysis patients. The serum concentration of 1,25(OH)2D3 was undetectable an...

journal_title：Nephron

authors： Shany S,Rapoport J,Goligorsky M,Yankowitz N,Zuili I,Chaimovitz C

更新日期：1984-01-01 00:00:00

abstract：:From a review of the literature regarding kinetic models used for assessing the adequacy of hemodialysis, no definite conclusions can be drawn as to whether the classical urea kinetic model (UKM) or modified direct dialysis quantification (mDDQ) is more reliable. We compared mDDQ with classical UKM and with a modified...

journal_title：Nephron

authors： Bosticardo GM,Alloatti S

更新日期：1996-01-01 00:00:00

abstract：:Postnephrectomy serum has been proved to enhance proliferation of mesangial cells in culture. Studies in offspring to uninephrectomized (UNx) mothers indicate that it remains active for a long period following UNx. On the other hand, postnephrectomy renal compensatory growth in vivo is known to be completed within a s...

journal_title：Nephron

authors： Weissgarten J,Modai D,Cohn M,Berman S,Averbukh Z

更新日期：1998-01-01 00:00:00

abstract：:Sprague-Dawley rats given gentamicin from 10 to 70 mg/kg/day for 9 days showed a linear decrease in glomerular filtration rate with increasing dose, paralleled by histologic changes of acute tubular necrosis and cast formation only at the higher doses. Nephrotoxicity was correlated with the peak, rather than trough, s...

journal_title：Nephron

authors： Sugarman A,Brown RS,Silva P,Rosen S

更新日期：1983-01-01 00:00:00

abstract：:The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with ...

journal_title：Nephron

authors： von Hartitzsch B,Kerr DN

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) is a crucial event in the development of renal interstitial fibrosis (RIF). A growing body of evidence indicates that β-catenin plays an important role in various types of fibrosis. Although members of the microRNA (miRNA)-200 family have been suggested to suppress...

journal_title：Nephron

authors： Gong Y,Qin Z,Zhou B,Chen H,Shi Z,Zhang J

更新日期：2017-01-01 00:00:00

abstract：:Using a 2-hour 47Ca absorption test, significant depression of active calcium absorption was demonstrated in 48 vitamin D untreated haemodialysis patients. This malabsorption of calcium could be corrected by the daily oral administration of 1--2 microgram of 1alphaOHD3 and 1--1.5 microgram of 1,25(OH)2D3. 5 microgram ...

journal_title：Nephron

authors： Pierides AM,Aljama P,Kerr DN,Scott M,Norman AW

更新日期：1978-01-01 00:00:00

abstract：:The effects of a high-protein (HP) and low-protein (LP) meal on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and renal vascular resistance (RVR) were examined in conscious dogs. Ingestion of the HP and LP meal produced a temporary increase in systemic hemodynamic parameters due in part to a 'c...

journal_title：Nephron

authors： Zawada ET,Saelens DA,Alavi FK,Lembke JM

更新日期：1994-01-01 00:00:00

abstract：:A total of 1,026 patients undergoing haemodialysis as the only chronic treatment were studied in all the dialysis units of the Veneto region, Italy. Aluminium was determined in water, dialysis fluids, and patients' serum. Aluminium mean concentration was 9.1 micrograms/l in tap water and 13.3 and 15.7 micrograms/l in ...

journal_title：Nephron

authors： Piccoli A,Andriani M,Mattiello G,Nordio M,Modena F,Dalla Rosa C

更新日期：1989-01-01 00:00:00

abstract：:Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign. We diagnosed Wilson's disease in a 17-year-old male patient 6 years after his first episode of gross hematuria and 2 years after detection of hypercalciuria and nephrocalcinos...

journal_title：Nephron

authors： Hoppe B,Neuhaus T,Superti-Furga A,Forster I,Leumann E

更新日期：1993-01-01 00:00:00

abstract：:Renin substrate concentrations and the release of renin in response to the rapid removal of 15 ml/kg weight blood or subcutaneous administration of 500 microgram/kg body weight isoproterenol were measured in control rats and animals recovering from prior myohemoglobinuric acute renal failure (recovery rats). Blood for...

journal_title：Nephron

authors： Carvalho JS,Landwehr DM,Oken DE

更新日期：1978-01-01 00:00:00

abstract：:A previous study from our laboratory has shown that erythropoietin (EPO), beside its traditional role in erythropoiesis, acts as an alleviator of oxidative stress and inflammation in chronic hemodialysis (HD) patients, conferred in part by activated polymorphonuclear leukocytes (PMNLs). To substantiate this phenomenon...

journal_title：Nephron

authors： Sela S,Shurtz-Swirski R,Sharon R,Manaster J,Chezar J,Shkolnik G,Shapiro G,Shasha SM,Merchav S,Kristal B

更新日期：2001-07-01 00:00:00

abstract：:The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group...

journal_title：Nephron

authors： Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

更新日期：1992-01-01 00:00:00

abstract：:In order to assess the effects of sodium depletion on tubular Na and H2O transport in man, renal clearance studies were performed under control conditions and after sodium depletion in 7 normal subjects. The control diet contained 250 mEq of Na daily. Sodium depletion was induced by placing subjects on a 20-mEq/day na...

journal_title：Nephron

authors： DiScala VA,Stein RM

更新日期：1982-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) is a histological pattern of podocyte and glomerulus injury. FSGS can be primary and secondary to other diseases or due to a genetic cause. Strikingly, genetic causes for adult-onset FSGS are often overlooked, likely because identifying patients with genetic forms of FSGS base...

journal_title：Nephron

authors： Snoek R,Nguyen TQ,van der Zwaag B,van Zuilen AD,Kruis HME,van Gils-Verrij LA,Goldschmeding R,Knoers NVAM,Rookmaaker MB,van Eerde AM

更新日期：2019-01-01 00:00:00

abstract：:Kidney biopsy remains the gold standard for uncovering the pathogenesis of acute and chronic kidney diseases. However, the ability to perform high resolution, quantitative, molecular and cellular interrogation of this precious tissue is still at a developing stage compared to other fields such as oncology. Here, we di...

journal_title：Nephron

authors： Winfree S,Dagher PC,Dunn KW,Eadon MT,Ferkowicz M,Barwinska D,Kelly KJ,Sutton TA,El-Achkar TM

更新日期：2018-01-01 00:00:00

abstract：:Propranolol-induced hypoglycemia in hemodialysis patients has been increasingly recognized. We studied the effects of a nonselective beta-blocker (propranolol) and a beta 1-selective-blocker (metoprolol) on glucose metabolism during pharmacologic hyperglucagonemia in these patients. cAMP and insulin responses to gluca...

journal_title：Nephron

authors： Pun KK,Yeung CK,Yeung RT

更新日期：1985-01-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：:In 92 renal transplant recipients, serum or plasma levels of neopterin were significantly elevated during pretransplant uremia, rejection, cyclosporin A induced nephrotoxicity and cytomegalovirus (CMV) infections. In patients with normal serum creatinine (less than 115 mumol/l) 71% had elevated serum neopterin levels....

journal_title：Nephron

authors： Bäckman L,Ringdén O,Björkhem I

更新日期：1987-01-01 00:00:00

abstract：:The present study was aimed to determine the effect of caffeine on the development of renal hypertension. Two-kidney, 1-clip (2K1C) hypertension and deoxycorticosterone acetate (DOCA, 200 mg/kg, subcutaneous implantation)-salt (0.9% NaCl drinking) hypertension were instituted in Sprague-Dawley rats. They were then gro...

journal_title：Nephron

authors： Choi KC,Lee J,Moon KH,Park KK,Kim SW,Kim NH

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:In the last decade, great advances have been made in the field of membranous nephropathy (MN). The autoimmune nature of the disease has been confirmed with the description of diverse antigens, and few but very important prospective trials regarding treatment alternatives have been published, changing profoun...

journal_title：Nephron

authors： Trujillo H,Alonso M,Praga M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Children with a solitary functioning kidney have a risk of renal injury caused by hyperfiltration. Timely intervention with renin-angiotensin inhibitors may be beneficial. We examined whether trajectory of estimated glomerular filtration rate (eGFR) would predict renal injury, defined as microalbuminuri...

journal_title：Nephron

authors： Matsumura K,Sugii K,Awazu M

更新日期：2018-01-01 00:00:00