Abstract:
:A 51-year-old man with diabetes mellitus and the nephrotic syndrome on renal biopsy was found to have diabetic glomerulosclerosis, amyloidosis and membranous glomerulopathy. The presence of three distinct glomerular diseases in the same patient is unique. Possible factors involved in their pathogenesis are discussed and the literature on concomitant glomerular diseases is reviewed.
journal_name
Nephronjournal_title
Nephronauthors
Bertani T,Olesnicky L,Abu-Regiaba S,Glasberg S,Pirani CLdoi
10.1159/000183026subject
Has Abstractpub_date
1983-01-01 00:00:00pages
260-6issue
4eissn
1660-8151issn
2235-3186journal_volume
34pub_type
杂志文章,评审相关文献
NEPHRON文献大全abstract:BACKGROUND/AIM:Acute renal failure (ARF) is one of the common problems associated with sepsis or multiple organ dysfunction syndrome (MODS). We have investigated the effects of inhibiting selectin-mediated cell adhesion on lipopolysaccharide-induced ARF in rabbits, using sialyl Lewis X oligosaccharide and PB1.3, an ant...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045942
更新日期:2001-04-01 00:00:00
abstract::Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045888
更新日期:2001-01-01 00:00:00
abstract::The capacity of peripheral blood mononuclear cells (PBMC) to undergo spontaneous and induced interleukin-1 (IL-1) production was examined in 10 healthy controls and in 10 patients undergoing intermittent hemodialysis (HD) using cuprophane membranes. Extracellular and cytoplasmic IL-1 activity was assayed by biologic a...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185187
更新日期:1988-01-01 00:00:00
abstract::A retrospective study of 100 patients followed for 1-4 years after successful renal transplantation was undertaken to assess the amelioration of previously present metabolic bone disease and to determine the risk factors associated with the development of osteonecrosis. 42% of patients showed some evidence of bony abn...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181455
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Urinary neutrophil gelatinase associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are markers of acute kidney injury. The albuminuria is a well-known abnormality after physical exercise. The aim of this study was to investigate changes in uNGAL and uKIM-1 after intensive exerc...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000481179
更新日期:2018-01-01 00:00:00
abstract::An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, theref...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180812
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:The development of abnormalities in red blood cell (RBC) deformability in patients undergoing hemodialysis remains a major problem, because it is related to peripheral microcirculation, oxygen supply, and various complications in such patients. gamma-Linolenic acid (GLA; 18:3n-6), one of the polyunsaturated ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000045729
更新日期:2000-10-01 00:00:00
abstract::The mechanisms by which intercurrent bacterial infections are associated with increased tissue injury in some forms of glomerulonephritis may include complement activation by bacteria and subsequent increased glomerular neutrophil (PMN) infiltration. We have studied the effect of complement activation after cobra veno...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185578
更新日期:1989-01-01 00:00:00
abstract::A 55-year-old white male, with silicosis diagnosed 10 years earlier, presented massive proteinuria with microscopic hematuria, moderate renal failure and distal polyneuropathy. Bilateral renal angiography showed multiple intraparenchymal saccular aneurysms. Renal biopsy disclosed a focal segmental necrotizing glomerul...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185391
更新日期:1989-01-01 00:00:00
abstract::To evaluate the patterns of renal images and the diagnostic value as a screening test of the whole-body bone and renal scintigraphy with technetium-99m-methylene diphosphonate (99mTc-MDP) or -pyrophosphate (99mTc-PYP), we performed bone scintigraphy in 6 patients with acute renal failure (ARF) with severe loin pain an...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186561
更新日期:1991-01-01 00:00:00
abstract::In this study we investigated the interactions between volume changes (body weight), plasma atrial natriuretic peptide (pANP) and ambulatory blood pressure (BP) in 10 patients with end-stage renal disease undergoing regular hemodialysis (HD) treatment three times weekly. Most patients retained their diurnal BP variati...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000189036
更新日期:1996-01-01 00:00:00
abstract::Serum concentrations of soluble interleukin 2 receptor (IL-2R) were measured in 65 hemodialysis patients and compared with serum levels of beta 2-microglobulin and tissue polypeptide antigen (TPA). Elevated IL-2R levels, found in 85% of examined patients, correlated with elevated TPA serum concentrations (p less than ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186125
更新日期:1990-01-01 00:00:00
abstract::We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183461
更新日期:1985-01-01 00:00:00
abstract::An autopsy case of membranous glomerulonephritis associated with enterococcal endocarditis was reported. Although enterococcal antigen was not identified in glomerular deposits, the eluate from the patient's renal tissue was shown to specifically recombine with cells of the enterococcus isolated from his own ante mort...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183435
更新日期:1985-01-01 00:00:00
abstract::Recent studies have shown that the mass transfer coefficients (MTC) for low- and middle-molecular-weight substances are maintained at medium terms in patients under continuous ambulatory peritoneal dialysis (CAPD) therapy. We have studied the MTC for parathormone (MW 5,500-6,000) in 29 patients under CAPD. 11 patients...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183201
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Peritoneal dialysis (PD) is an ideal model for testing remote monitoring (RM). In this study, we evaluated the RM application longitudinally in stable patients undergoing automated PD (APD). METHODS:This was an observational study, comparing outcomes in patients with (current patients) and without (historic...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000496182
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND/AIM:Interleukin (IL)-17 is a newly discovered cytokine that is secreted by activated memory CD4+ T cells and modulated the early stage of immune response. To elucidate the pathophysiology of minimal-change nephrotic syndrome (MCNS), we focused on IL-17, which is one of the key factors in regulating an inflam...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000058399
更新日期:2002-06-01 00:00:00
abstract::Decreased serum levels of high-density lipoprotein cholesterol (HDL-C) are a well-known risk factor for coronary heart disease (CHD) in the general population and have been suggested as one of the best predictor of CHD after renal transplantation. However, very heterogeneous HDL-C levels have been reported in renal tr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045608
更新日期:2000-04-01 00:00:00
abstract::8 patients who developed proteinuria whilst receiving penicillamine for rheumatoid arthritis have been studied. Light microscopy of renal biopsy specimens showed evidence of an extramembranous nephropathy in 6 cases, with epimembranous spikes infrequently described previously in association with penicillamine. ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181984
更新日期:1980-01-01 00:00:00
abstract::The sera of 64 patients with extracapillary glomerulonephritis were investigated by enzyme-linked immunosorbent assay for the presence of antibody to human neutrophil myeloperoxidase (MPO). In all, circulating anti-MPO were found in 30% and antineutrophil cytoplasm antibodies (ANCA) detected by indirect immunofluoresc...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186124
更新日期:1990-01-01 00:00:00
abstract::Conjugated diene fatty acids (CDFA) were evaluated by second derivative spectrophotometry in the plasma and adipose tissue of 42 chronic renal failure (CFR) patients in conservative treatment, 40 patients treated by hemodialysis (HD) with cuprophane, cellulose acetate or hemophan, 29 treated by hemodiafiltration (HDF)...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187520
更新日期:1993-01-01 00:00:00
abstract::This paper reviews the control of aldosterone secretion, including the role played by hepatic metabolic clearance, ACTH, and the renin-angiotensin system, and the interrelationships of aldosterone secretion with sodium and potassium metabolism. The physiological modulations of aldosterone secretion by the upright post...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181613
更新日期:1979-01-01 00:00:00
abstract::The study aimed to evaluate the behavior of alpha-glutathione S-transferase (alpha-GST) in the serum of hemodialysis patients with hepatitis C virus (HCV) infection following treatment with high-dose IFN-alpha-2b. Ten patients with detected anti-HCV antibodies and HCV RNA by RT-PCR were selected and treated with high-...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045363
更新日期:1999-01-01 00:00:00
abstract::29 patients receiving haemodialysis treatment for chronic renal failure were divided into two groups on the basis of the presence or absence of bone disease as defined by radiology and bone alkaline phosphatase. The group of patient with bone disease showed a significantly greater increase in protein-bound calcium dur...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181632
更新日期:1979-01-01 00:00:00
abstract::The effect of water immersion to the neck on renal calcium and magnesium handling was studied in 11 nephrotic patients. There was an increase in the urinary excretion of both calcium and magnesium on immersion, and a return towards preimmersion control values in the hour following immersion. Clearances of calcium and ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182897
更新日期:1983-01-01 00:00:00
abstract::The present study was conducted to examine potassium lowering effect of exogenous mineralocorticoid (fludrocortisone acetate; FCA) administration to the patients with chronic renal failure undergoing hemodialysis. Fifteen patients on hemodialysis receiving FCA with its dosage gradually increased from 0 to 0.20 mg/day ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000064116
更新日期:2002-01-01 00:00:00
abstract::A 58-year-old woman who suffered from a heterozygous Fabry's disease and immune complex crescentic glomerulonephritis (GN) is reviewed. The diagnosis was made on the basis of the pathologic findings and peripheral leukocyte alpha-galactosidase activity. Light microscopy revealed a vacuolization of epithelial cells and...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000063287
更新日期:2002-10-01 00:00:00
abstract::Using a 2-hour 47Ca absorption test, significant depression of active calcium absorption was demonstrated in 48 vitamin D untreated haemodialysis patients. This malabsorption of calcium could be corrected by the daily oral administration of 1--2 microgram of 1alphaOHD3 and 1--1.5 microgram of 1,25(OH)2D3. 5 microgram ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181223
更新日期:1978-01-01 00:00:00
abstract::Diffuse crescentic glomerulonephritis was observed in a 40-year-old male patient who had a ventriculoatrial shunt implanted after a traffic accident 10 years previously. Immediately after treatment with immunosuppressants and plasma pheresis, signs of meningitis and septicemia developed. The responsible organism isola...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183441
更新日期:1985-01-01 00:00:00
abstract::Chronic cyclosporine nephrotoxicity is characterized morphologically by cortical interstitial fibrosis. The most important collagens involved in renal fibrosis are collagen types I and III. In order to estimate the synthesis of type III and type I collagens, we analyzed serum levels of the amino-terminal propeptide of...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187929
更新日期:1994-01-01 00:00:00