Control of aldosterone secretion.

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:A four-year-old male with steroid refractory nephrotic syndrome was found to have diffuse deposition of alpha 2-macroglobulin (alpha 2M) in the glomeruli which showed diffuse mesangial proliferation and partial hyalinization by light microscopy. Camostat mesylate, a commercially available synthetic proteinase inhibito...

journal_title：Nephron

authors： Asami T,Ohsawa S,Tomisawa S,Hashimoto K,Toyabe S,Sakai K

更新日期：1992-01-01 00:00:00

abstract：:The concentration changes, during hemodialysis treatment, of 18 characteristic uremia compounds, analyzed by high-pressure liquid chromatography in sera of renal patients were studied. Pre- to postdialysis concentration ratios (dialysis ratio, D) varied from 0.83 to 3.04 for the different solutes. A division into thre...

journal_title：Nephron

authors： Schoots AC,Peeters JA,Gerlag PG

更新日期：1989-01-01 00:00:00

abstract：:Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign. We diagnosed Wilson's disease in a 17-year-old male patient 6 years after his first episode of gross hematuria and 2 years after detection of hypercalciuria and nephrocalcinos...

journal_title：Nephron

authors： Hoppe B,Neuhaus T,Superti-Furga A,Forster I,Leumann E

更新日期：1993-01-01 00:00:00

abstract：:Mean renal blood flow (MRBF), cortical blood flow (CBF), glomerular filtration rate (GFR), heart rate, arterial blood pressure, Na+ and K+ excretion were determined before and 10 min after intrarenal administration of dihydroergocristine (0.017 mg/kg b.w.) in 13 patients suffering from liver cirrhosis. Cardiac output ...

journal_title：Nephron

authors： Gatta A,Merkel C,Grassetto M,Milani L,Zuin R,Ruol A

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Progressive nephropathy is one of the main features of Fabry disease (FD). It has been supposed that an early phase, clinically silent disease occurs in childhood and adolescence and is characterized by glomerular hyperfiltration (HF). Surprisingly, although HF has been reported in several stu...

journal_title：Nephron

authors： Riccio E,Sabbatini M,Bruzzese D,Annicchiarico Petruzzelli L,Pellegrino A,Spinelli L,Esposito R,Imbriaco M,Feriozzi S,Pisani A,on behalf of AFFIINITY Group.

更新日期：2019-01-01 00:00:00

abstract：:Mizoribine has been shown to possess an immunosuppressive action that inhibits the proliferation of lymphocytes selectively by interfering with inosine monophosphate dehydrogenase. Recent studies have demonstrated that mizoribine improves renal tubulointerstitial fibrosis in the rat model of unilateral ureteral obstru...

journal_title：Nephron

authors： Sato N,Shiraiwa K,Kai K,Watanabe A,Ogawa S,Kobayashi Y,Yamagishi-Imai H,Utsunomiya Y,Mitarai T

更新日期：2001-10-01 00:00:00

abstract：:In 25 patients with nephrotic syndromes of different origin, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion. This effect of indomethacin on GFR and proteinuria was more pronounced when the renin-angiotensin system was stimulated by a low-sodium diet and 50 m...

journal_title：Nephron

authors： Donker AJ,Brentjens JR,van der Hem GK,Arisz L

更新日期：1978-01-01 00:00:00

abstract：:The authors utilized two groups of adult male rats to study the effect of chronic-uremic toxemia on the synthesis of thyroid hormones. The control group was sham operated, while the other group had about 70--80% of the left kidney tissue surgically excised and a total right nephrectomy performed 10 days later. At the ...

journal_title：Nephron

authors： Costa e Silva A,Albuquerque RH,Santana JP

更新日期：1978-01-01 00:00:00

abstract：:In normal subjects, the gastric ionisation of calcium and phosphate seems to be a prerequisite for their intestinal absorption. We investigated the behavior of the plasma calcium and phosphate profile in 30 patients on regular dialysis treatment in the 6 h following a meal containing 1 g of calcium and 2 g of phosphat...

journal_title：Nephron

authors： Graziani G,Badalamenti S,Como G,Gallieni M,Finazzi S,Angelini C,Brancaccio D,Ponticelli C

更新日期：2002-07-01 00:00:00

abstract：:In an attempt to clarify the renal involvement induced by human parvovirus B19 (HPB19) infection, we investigated 6 adult patients with transient urinary abnormalities followed by erythema infectiosum. All patients had HPB19-specific IgM antibody and showed mild proteinuria of 0.2-1.2 g/day with or without microscopic...

journal_title：Nephron

authors： Takeda S,Takaeda C,Takazakura E,Haratake J

更新日期：2001-11-01 00:00:00

abstract：:Dialysate effluent protein content was measured in 22 patients undergoing continuous ambulatory peritoneal dialysis (9 with and 13 without previous peritonitis). The average amount of protein in those patients without peritonitis was 1.3 g/2 liters exchanged over a 6-hour period, while that of patients with previous p...

journal_title：Nephron

authors： Katirtzoglou A,Oreopoulos DG,Husdan H,Leung M,Ogilvie R,Dombros N

更新日期：1980-01-01 00:00:00

abstract：:We examined the types of guanine nucleotide-binding regulatory (G) protein subunits in isolated glomeruli, cortices excluding glomeruli and medullas of rat kidneys using bacterial toxin-catalyzed adenosine 5'-diphosphate (ADP) ribosylation and specific immunoblots. ADP ribosylation catalyzed by cholera or pertussis to...

journal_title：Nephron

authors： Yanagisawa H,Kurihara N,Klahr S,Morrissey J,Wada O

更新日期：1994-01-01 00:00:00

abstract：AIM:To clarify the role of leukocyte subsets in the development of glomerulosclerosis (GS) and interstitial lesions which may contribute to the prognosis of membranous nephropathy (MN), we investigated infiltrating cells in both glomeruli and interstitium in biopsy specimens. METHODS:Forty-one cases of MN were divided...

journal_title：Nephron

authors： Saito T,Yusa A,Soma J,Ootaka T,Sato H,Ito S

更新日期：1998-12-01 00:00:00

abstract：:Blood eosinophils were counted by the counting-chamber method in 21 regular hemodialysis patients. Before dialysis, eosinophil counts were within the normal range in all patients (mean 98 cells/mm3, range 6-350). After the first 15 min of hemodialysis, with not reused coils or hollow-fiber dialysers, a significant dro...

journal_title：Nephron

authors： Bodner G,Peer G,Zakuth V,Spirer ZH,Aviram A

更新日期：1982-01-01 00:00:00

abstract：:The pharmacokinetics of procainamide in patients on continuous ambulatory peritoneal dialysis have been studied. A mean peak plasma concentration of 3.2 +/- 0.6 microgram/ml was achieved about 2 h after a single 500-mg oral procainamide hydrochloride dose. The procainamide elimination half-life ranged from 6.1 to 15.3...

journal_title：Nephron

authors： Raehl CL,Moorthy AV,Beirne GJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:The renal prognosis of post-renal acute kidney injury (PoR-AKI) has not been verified so far. The objective of this study was to assess the association of baseline anemia with long-term renal prognosis in patients with PoR-AKI. METHODS:We performed a multicenter retrospective cohort study. Consecutive ...

journal_title：Nephron

authors： Sasaki S,Kawarazaki H,Hasegawa T,Shima H,Naganuma T,Shibagaki Y

更新日期：2017-01-01 00:00:00

abstract：:Copper (Cu) and zinc (Zn) were measured in urine, serum and tissues from rats with nephrotic syndrome (NS) induced with a single subcutaneous dose of puromycin aminonucleoside (PAN; 15 mg/100 g BW). Control animals were pair-fed. Urine was collected daily, and the rats were sacrificed on day 10. PAN-nephrotic rats had...

journal_title：Nephron

authors： Pedraza-Chaverrí J,Torres-Rodríguez GA,Cruz C,Mainero A,Tapia E,Ibarra-Rubio ME,Silencio JL

更新日期：1994-01-01 00:00:00

abstract：:The effect of ischemia on renal blood flow (RBF) in the rat has been an unsettled question. This study used a totally extractable indicator, radioactive microspheres, with a reference arterial sample, to study RBF quantitatively 10 and 60 min after 1 h of unilateral renal artery clamping in anesthetized, heparinized r...

journal_title：Nephron

authors： Riley AL

更新日期：1978-01-01 00:00:00

abstract：:The kinetics of bromosulfophthalein clearance from plasma, secretion into bile, and, by difference, storage in hepatic cells, were determined, using normal livers and blood from normal rats in the isolated perfused rat liver system. Two suspected uremic 'toxins', urea and guanidinosuccinic acid, were then administered...

journal_title：Nephron

authors： Liang MY,Toporek M,Schepartz B

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Idiopathic membranous nephropathy remains the leading cause of nephrotic syndrome in Caucasian adults. Immunosuppressive therapy with cyclosporine (CSA) is often successful in reducing proteinuria, but its use is associated with a high relapse rate. Rituximab, a monoclonal antibody that specifically targets ...

journal_title：Nephron

authors： Fervenza FC,Canetta PA,Barbour SJ,Lafayette RA,Rovin BH,Aslam N,Hladunewich MA,Irazabal MV,Sethi S,Gipson DS,Reich HN,Brenchley P,Kretzler M,Radhakrishnan J,Hebert LA,Gipson PE,Thomas LF,McCarthy ET,Appel GB,Jeffers

更新日期：2015-01-01 00:00:00

abstract：:The serum levels of 25-hydroxycholecalciferol, 24,25-dihydroxycholecalciferol, and 1,25-dihydroxycholecalciferol were measured simultaneously in three groups of adults with different renal function: normal (n = 24), glomerular filtration rate (GFR) greater than 70 ml/min; moderately decreased (n = 15), GFR 5-35 ml/min...

journal_title：Nephron

authors： Rickers H,Christiansen C,Christensen P,Christensen M,Rødbro P

更新日期：1985-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:The clinicopathological findings of isolated mesangial C3d deposition in the absence of other complement components or immunoglobulins are summarized. 55 out of 242 individual human renal biopsies examined by immunoperoxidase microscopy had isolated C3d deposition. This group consisted of 12 patients with chronic glom...

journal_title：Nephron

authors： Doi T,Kanatsu K,Suehiro F,Nagai H,Yoshida H,Hamashima Y

更新日期：1987-01-01 00:00:00

abstract：:The effect of uremia upon the hepatic clearance rate of prednisone was studied in isolated perfused livers of normal and uremic female rats. The perfusion rate was kept at a constant flow rate of 25 ml/min. In order to induce uremia, one group of rats was 5/6 nephrectomized 3 weeks prior to the perfusions. The concent...

journal_title：Nephron

authors： Egfjord W,Langhoff E,Daugaard H,Olgaard K

更新日期：1987-01-01 00:00:00

abstract：:The frequency of thrombocytopenia in patients with chronic renal failure (CRF) is controversial. This study was undertaken to investigate the platelet count in 55 patients with end-stage renal disease on maintenance hemodialysis and in 19 patients with CRF before hemodialysis had begun. In both groups platelet counts ...

journal_title：Nephron

authors： Gafter U,Bessler H,Malachi T,Zevin D,Djaldetti M,Levi J

更新日期：1987-01-01 00:00:00

abstract：:A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia in the lower extremities and elevated serum aminotransferase levels. His viral markers and other factors that may cause myal...

journal_title：Nephron

authors： Caglar K,Safali M,Yavuz I,Odabaşi Z,Yenicesu M,Vural A

更新日期：2002-12-01 00:00:00

abstract：:The course of left ventricular hypertrophy was investigated in anemic hemodialysis patients treated with recombinant human erythropoietin (r-huEPO). 12 patients, aged 60.8 +/- 9.9 years (mean +/- SD) were treated for 18.8 +/- 2.7 months. Left ventricular size was estimated by echocardiography performed before treatmen...

journal_title：Nephron

authors： Zehnder C,Zuber M,Sulzer M,Meyer B,Straumann E,Jenzer HR,Blumberg A

更新日期：1992-01-01 00:00:00

abstract：:The recent experience of six large trials of antihypertensive therapy has not clearly demonstrated any beneficial effect on the prevention of coronary heart disease (CHD). The data from the HDFP study have been analyzed by three cholesterol strata at baseline. The higher the baseline cholesterol levels, the greater th...

journal_title：Nephron

authors： Schneider KA,Heyden S,Ford C

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Urinary neutrophil gelatinase associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are markers of acute kidney injury. The albuminuria is a well-known abnormality after physical exercise. The aim of this study was to investigate changes in uNGAL and uKIM-1 after intensive exerc...

journal_title：Nephron

authors： Wołyniec W,Ratkowski W,Urbański R,Bartoszewicz M,Siluk D,Wołyniec Z,Kasprowicz K,Zorena K,Renke M

更新日期：2018-01-01 00:00:00