Serum concentrations of vitamin D metabolites in different degrees of impaired renal function. Estimation of renal and extrarenal secretion rate of 24,25-dihydroxyvitamin D.

abstract：:A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...

journal_title：Nephron

authors： Takeuchi A,Yoshizawa N,Oshima S,Kubota T,Oshikawa Y,Akashi Y,Oda T,Niwa H,Imazeki N,Seno A

更新日期：1992-01-01 00:00:00

abstract：:The investigation of a sample of 99 women on maintenance hemodialysis has shown the presence of sexual disturbances to a great extent: the rate of sexual intercourse and the ability to reach orgasm were significantly lower than in age-matched control women. 80% declared a reduction in their sexual desire and the frequ...

journal_title：Nephron

authors： Mastrogiacomo I,De Besi L,Serafini E,Zussa S,Zucchetta P,Romagnoli GF,Saporiti E,Dean P,Ronco C,Adami A

更新日期：1984-01-01 00:00:00

abstract：:Plasma renin reactivity (PRR) is the in vitro rate of angiotensin generation after addition of exogenous renin to plasma. The purpose of the present study is to compare measurements of PRR in venous effluent from the involved and uninvolved kidneys in both experimental and clinical renovascular hypertension. A two-kid...

journal_title：Nephron

authors： Kotchen TA,Welch WJ,Daugherty M,Ernst CB

更新日期：1977-01-01 00:00:00

abstract：:During chronic chlorthalidone treatment of patients with essential hypertension, distal tubular sodium reabsorption is continuously inhibited. At the same time, sodium balance is maintained by an increase of the proximal tubular sodium reabsorption. In the present study, we investigated whether this increase is caused...

journal_title：Nephron

authors： van Schaik BA,Geyskes GG,Dorhout Mees EJ

更新日期：1987-01-01 00:00:00

abstract：:Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis. Five patients were studied before and after 1 week of dietary sodium restriction in order to examine the possibility that increased extrac...

journal_title：Nephron

authors： Schacht RG,Steele JM Jr,Lowenstein J,Baldwin DS

更新日期：1977-01-01 00:00:00

abstract：:In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...

journal_title：Nephron

authors： Lenz T,Thiede HM,Nussberger J,Atlas SA,Distler A,Schulte KL

更新日期：1992-01-01 00:00:00

abstract：:We reviewed the recommendations and outcomes for all patients with diabetes mellitus and end-stage renal disease referred to the Medical Center Hospital of Vermont from 1971 through December 1983. During this period, we recommended transplantation in 53 of 73 patients evaluated. Thirty-two transplants were performed i...

journal_title：Nephron

authors： Rimmer JM,Sussman M,Foster R,Gennari FJ

更新日期：1986-01-01 00:00:00

abstract：:A 55-year-old white male, with silicosis diagnosed 10 years earlier, presented massive proteinuria with microscopic hematuria, moderate renal failure and distal polyneuropathy. Bilateral renal angiography showed multiple intraparenchymal saccular aneurysms. Renal biopsy disclosed a focal segmental necrotizing glomerul...

journal_title：Nephron

authors： Arnalich F,Lahoz C,Picazo ML,Monereo A,Arribas JR,Martínez Ara J,Vázquez JJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND/AIMS:In our earlier studies, we reported high concentrations of intra- and extracellular calcium ions (Ca2+) in the deeper epidermis of patients with chronic kidney disease (CKD) and associated pruritus. To determine the cause of this phenomenon, we measured total calcium (TCa) concentrations in the deeper e...

journal_title：Nephron

authors： Momose A,Shiraiwa Y,Narita S,Kusumi T,Goto S,Sera K

更新日期：2017-01-01 00:00:00

abstract：:Dysfunction of the host defense against infection in hemodialysis (HD) patients has major clinical and socioeconomic implications. T helper type 1 (Th1) and type 2 (Th2) cytokines are implicated in regulating the immune responses and, therefore, may be involved in impaired status. The present study was designed to exa...

journal_title：Nephron

authors： Daichou Y,Kurashige S,Hashimoto S,Suzuki S

更新日期：1999-01-01 00:00:00

abstract：:351 sera from 27 human recipients of renal allografts and 21 healthy blood donors were assayed for circulating immune complexes by the Clq solid-phase radioimmune assay. Increased Clq-binding activity (Clq-BA) was detected in pretransplant sera from 5 patients with chronic pyelonephritis (PN) and 3 patients with chron...

journal_title：Nephron

authors： Kaden J,Falck P,Groth J,Mebel M

更新日期：1981-01-01 00:00:00

abstract：:A 4-year-old girl, who had been in perfect health, presented with the acute onset of renal failure and abdominal mass. Investigations revealed a solitary left kidney which on histology had the typical features of xanthogranulomatous pyelonephritis. The child had no previous history suggestive of chronic renal disease ...

journal_title：Nephron

authors： Noah M,Schoeneman MJ,Haycock G,Levitt SB,Bennett B,Greifer I

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Bleeding is the most frequent complication of kidney biopsy. Although bleeding risk in patients with AA amyloidosis after kidney biopsy has not been studied in a large population, AA amyloidosis has long been perceived as a risk factor for bleeding. The aim of the present study was to evaluate post-biopsy bl...

journal_title：Nephron

authors： Altindal M,Yildirim T,Turkmen E,Unal M,Boga I,Yilmaz R,Arici M,Altun B,Erdem Y

更新日期：2015-01-01 00:00:00

abstract：:The effect of treatment with 1 alpha-hydroxycholecalciferol (1 alpha-OH-D3) and different diets on uremic arterial disease was studied. Three groups of rabbits with chronic renal failure (CRF) were kept on three diets with a low, medium or high content of calcium and phosphate. Half the rabbits in each group were trea...

journal_title：Nephron

authors： Tvedegaard E,Ladefoged O,Nielsen M,Kamstrup O

更新日期：1983-01-01 00:00:00

abstract：:The daily urinary excretion of oxalate has been found to be lower than normal in patients with renal failure and the decrease to be directly proportional to the impairment of renal function. It has also been found that the gut flora from uremic patients destroys oxalate 'in vitro' more efficiently than the gut flora f...

journal_title：Nephron

authors： Camici M,Balestri PL,Lupetti S,Colizzi V,Falcone G

更新日期：1982-01-01 00:00:00

abstract：:Experiences with peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) program at a single center over 8 years were reviewed. Home-acquired peritonitis rates have been less than 1 episode per patient year since 1982. Gram-positive organisms continue to account for most episodes in a similar proportion. Act...

journal_title：Nephron

authors： Prowant B,Nolph K,Ryan L,Twardowski Z,Khanna R

更新日期：1986-01-01 00:00:00

abstract：:Cyclosporine (CsA) nephrotoxicity is partially mediated by renal vasoconstriction due to an imbalance between vasodilator and vasoconstrictor eicosanoids. LSL 90202 is a purified lysine salt of eicosapentaenoic acid which is a known inhibitor of renal eicosanoid synthesis. The aim of the present work was to determine ...

journal_title：Nephron

authors： Torras J,Valles J,Sanchez J,Sabate I,Seron D,Carrera M,Castelao AM,Herrero I,Puig-Parellada P,Alsina J

更新日期：1994-01-01 00:00:00

abstract：:We found a strain of nonobese, nondiabetic (NON) mice which has spontaneous lipid deposition in glomerular capillary lumina. This strain was developed together with a diabetic strain of nonobese diabetic (NOD) mice for the generation of mouse models of diabetes mellitus. In the NON strain, contrary to the name, impair...

journal_title：Nephron

authors： Watanabe Y,Itoh Y,Yoshida F,Koh N,Tamai H,Fukatsu A,Matsuo S,Hotta N,Sakamoto N

更新日期：1991-01-01 00:00:00

abstract：:We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...

journal_title：Nephron

authors： Derbyshire ND,Asscher AW,Matthews PN

更新日期：1989-01-01 00:00:00

abstract：:Recurrent intradialytic hypotension is probably the most severely disabling feature in dialysis patients and the etiology is multifactorial. We assessed the efficacy and safety of midodrine, a selective alpha1-adrenergic pressor agent in 12 patients with recurrent intradialytic hypotension. Symptomatic intradialytic h...

journal_title：Nephron

authors： Lim PS,Yang CC,Li HP,Lim YT,Yeh CH

更新日期：1997-01-01 00:00:00

abstract：:To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

journal_title：Nephron

authors： Duan SB,Wu HW,Luo JA,Liu FY

更新日期：1999-01-01 00:00:00

abstract：:Proteoglycans constitute a heterogenous group of complex macromolecules, consisting of a backbone core protein and a variable number of sulfated polysaccharide side chains covalently linked to the core. A dual function for these polyanionic glycosaminoglycans in kidney physiology has been proposed: to maintain a fixed...

journal_title：Nephron

authors： Pyke C,Kristensen P,Ostergaard PB,Oturai PS,Rømer J

更新日期：1997-01-01 00:00:00

abstract：:The clinical profile of a patient with a 15 years' evolution of acne conglobata developing systemic amyloidosis with severe renal involvement is described, and the possible influence of suppurative skin foci surgical excision on the rapid progression to terminal renal failure is discussed. This etiological cause of se...

journal_title：Nephron

authors： Naya MT,Soria C,Quereda C,Orte L,Romero R,Ortuño J

更新日期：1991-01-01 00:00:00

abstract：:To clarify the reliability of urinary trehalase activity as a marker of cellular proliferation and/or damage of renal proximal tubules, the activity was examined in healthy newborn infants or infants treated with tobramycin, a drug known as causing tubular cell damage. Eighty-one newborn infants (56 mature infants and...

journal_title：Nephron

authors： Sasai-Takedatsu M,Kojima T,Taketani S,Ono A,Kitamura N,Kobayashi Y

更新日期：1995-01-01 00:00:00

abstract：:Since 1987, we have experienced 11 children with acute renal failure (ARF) associated with Yersinia pseudotuberculosis (YP) infection. The illness began with the sudden onset of high fever, skin rash and gastrointestinal symptoms. Later in the course, periungual desquamation developed, mimicking Kawasaki disease. Elev...

journal_title：Nephron

authors： Cheong HI,Choi EH,Ha IS,Lee HJ,Choi Y

更新日期：1995-01-01 00:00:00

abstract：:A previous study from our laboratory has shown that erythropoietin (EPO), beside its traditional role in erythropoiesis, acts as an alleviator of oxidative stress and inflammation in chronic hemodialysis (HD) patients, conferred in part by activated polymorphonuclear leukocytes (PMNLs). To substantiate this phenomenon...

journal_title：Nephron

authors： Sela S,Shurtz-Swirski R,Sharon R,Manaster J,Chezar J,Shkolnik G,Shapiro G,Shasha SM,Merchav S,Kristal B

更新日期：2001-07-01 00:00:00

abstract：:We examined the types of guanine nucleotide-binding regulatory (G) protein subunits in isolated glomeruli, cortices excluding glomeruli and medullas of rat kidneys using bacterial toxin-catalyzed adenosine 5'-diphosphate (ADP) ribosylation and specific immunoblots. ADP ribosylation catalyzed by cholera or pertussis to...

journal_title：Nephron

authors： Yanagisawa H,Kurihara N,Klahr S,Morrissey J,Wada O

更新日期：1994-01-01 00:00:00

abstract：CONTEXT:Soluble urokinase-type plasminogen activator -(suPAR) is an inflammatory signal with pleiotropic biological effects depending on context and post-translational modifications. Recently, [Hayek, et al: Nat Med 2017; 23: 945-953] it has been found that there is a link between suPAR and renal disease in several gui...

journal_title：Nephron

authors： Saleem MA

更新日期：2018-01-01 00:00:00

abstract：:A 2-year prospective study was done in 45 patients to see whether the FENa test, done at first nephrology consultation visit for acute renal failure, was useful in prognosticating whether patients would recover renal function spontaneously or need dialysis. Of 26 patients who recovered renal function spontaneously, 8 ...

journal_title：Nephron

authors： Pru C,Kjellstrand CM

更新日期：1984-01-01 00:00:00

abstract：:The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...

journal_title：Nephron

authors： Zachée P,Daelemans R,Pollaris P,Boogaerts MA,Lins RL

更新日期：1994-01-01 00:00:00