Abstract:
:The daily urinary excretion of oxalate has been found to be lower than normal in patients with renal failure and the decrease to be directly proportional to the impairment of renal function. It has also been found that the gut flora from uremic patients destroys oxalate 'in vitro' more efficiently than the gut flora from normal people. It is postulated that an adaptation occurs in the gut flora of uremics to 'metabolize' oxalate, and this enteric elimination may account for its decreased urinary excretion.
journal_name
Nephronjournal_title
Nephronauthors
Camici M,Balestri PL,Lupetti S,Colizzi V,Falcone Gdoi
10.1159/000182486subject
Has Abstractpub_date
1982-01-01 00:00:00pages
269-70issue
3eissn
1660-8151issn
2235-3186journal_volume
30pub_type
杂志文章相关文献
NEPHRON文献大全abstract::The mechanisms by which intercurrent bacterial infections are associated with increased tissue injury in some forms of glomerulonephritis may include complement activation by bacteria and subsequent increased glomerular neutrophil (PMN) infiltration. We have studied the effect of complement activation after cobra veno...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185578
更新日期:1989-01-01 00:00:00
abstract::Computerized tomography (CT) has the advantage of allowing the isolation of trabecular bone of the axial skeleton, which is the more sensitive to metabolic changes. By means of single-energy X-ray CT we have devised a method for assessing trabecular bone mass (TBM) at L-4 vertebral body, which has an acceptable reprod...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184007
更新日期:1986-01-01 00:00:00
abstract::The morphologic basis of proteinuria in experimental chronic serum sickness glomerulonephritis in rabbits was studied by light and electron microscopy using horseradish peroxidase (effective radius 30 A; mol. wt. 40,000) and ferritin (effective radius 60 A; mol. wt. 480,000) as protein tracers. It was found that more ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181260
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Cyst infection is a frequent and serious complication of autosomal dominant polycystic kidney disease (ADPKD) that is often difficult to treat. However, the factors influencing cyst infection are still unknown. Therefore, we investigated clinical factors related to the duration of hospitalization and death d...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000493806
更新日期:2019-01-01 00:00:00
abstract::The decarboxylation and transamination reactions of glyoxylate, which divert this precursor from oxalate formation, have been investigated. Decarboxylation of glyoxylate is synergistic with 2-oxoglutarate and catalysed by 2-oxoglutarate:glyoxylate carboligase which co-chromatographs with the 2-oxoglutarate dehydrogena...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186350
更新日期:1991-01-01 00:00:00
abstract::A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000180439
更新日期:1975-01-01 00:00:00
abstract:CONTEXT:The widespread use of diuretics, potassium supplements, and medications that block renin angiotensin system puts the chronic kidney disease (CKD) population at high risk for dyskalemia, both hyperkalemia and hypokalemia. The optimal potassium level in a CKD patient is unknown. Subject of review: Two recent stud...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000490008
更新日期:2018-01-01 00:00:00
abstract::In earlier studies, we have shown that induction of passive Heymann nephritis (PHN) by intrarenal infusion of anti-Fx1A antibodies provokes an immediate fall in renal blood flow (RBF) and glomerular filtration rate (GFR). This was probably mediated via the complement system, as infusion of the F(ab')2 fraction of anti...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186808
更新日期:1992-01-01 00:00:00
abstract::ExHC rats were bred from the Sprague-Dawley strain and are highly susceptible to dietary hypercholesterolemic stimuli. Although chemical and histological examination of the aorta from ExHC rats fed a diet containing 3% cholesterol, 0.6% sodium cholate and 15% olive oil (high-cholesterol diet, HCD) has been reported, r...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187216
更新日期:1993-01-01 00:00:00
abstract::A 64-year-old woman presenting with a history of increasing oedema was found to have nephrotic syndrome with a 24-hour urinary protein excretion of 20.7 g and renal impairment with an initial serum creatinine level of 197 mumol/l (2.16 mg/dl). A renal tumour was demonstrated by ultrasound scanning and subsequent nephr...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000188434
更新日期:1995-01-01 00:00:00
abstract::Serum concentrations of soluble interleukin 2 receptor (IL-2R) were measured in 65 hemodialysis patients and compared with serum levels of beta 2-microglobulin and tissue polypeptide antigen (TPA). Elevated IL-2R levels, found in 85% of examined patients, correlated with elevated TPA serum concentrations (p less than ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186125
更新日期:1990-01-01 00:00:00
abstract::In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187071
更新日期:1992-01-01 00:00:00
abstract::Gastrointestinal infection with verotoxin-producing Escherichia coli (VTEC) has been strongly implicated in the etiology of the hemolytic uremic syndrome (HUS), the leading cause of pediatric acute renal failure. The binding of fluorescein-conjugated VT1 overlaid on to frozen human renal sections has been examined. Se...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187761
更新日期:1994-01-01 00:00:00
abstract::Mixed IgM-IgG cryoglobulins were present in the serum of a patient with the nephrotic syndrome, recurrent purpura, chronic active hepatitis and ascites. A renal biopsy demonstrated deposition of IgM, IgG, and complement components C3 and C4 in intracapillary 'coagula' and glomerular capillary walls. No glomerular depo...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180591
更新日期:1976-01-01 00:00:00
abstract::The variations of ionized and total calcium concentrations were studied during haemodialysis with high flux membrane using dialysate calcium concentrations of 1.63 and 1.76 mmol/l. The changes in ionized and total calcium were related to the predialytic calcium concentration difference between plasma and dialysate. Th...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184951
更新日期:1988-01-01 00:00:00
abstract::Decreased serum levels of high-density lipoprotein cholesterol (HDL-C) are a well-known risk factor for coronary heart disease (CHD) in the general population and have been suggested as one of the best predictor of CHD after renal transplantation. However, very heterogeneous HDL-C levels have been reported in renal tr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045608
更新日期:2000-04-01 00:00:00
abstract::We describe a case, seemingly sporadic, in which ocular and acral malformations were associated with an interstitial nephropathy; we made a diagnosis of acro-renal-ocular syndrome. There was no stasis, reflux, or urinary tract infection in our patient. We believe that interstitial nephritis in acro-renal-ocular syndro...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187896
更新日期:1994-01-01 00:00:00
abstract::The decreases in serum osmolality as well as the rate of ultrafiltration during hemodialysis and the influence of each upon the side effects of this treatment were studied in 13 chronic stable dialysis patients. Mannitol (9 mosm/kg water) was infused in two out of four dialyses, in a double blind fashion. A solution o...
journal_title:Nephron
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000182039
更新日期:1981-01-01 00:00:00
abstract::This study was conducted to test the hypothesis that the margin of safe fluoride exposure is narrowed in rats that are physiologically compromised by renal dysfunction. The study objective was to determine whether increases in fluoride retention and tissue fluoride levels in rats with surgically induced renal insuffic...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000044888
更新日期:1998-01-01 00:00:00
abstract::We measured peritoneal losses of the active vitamin D metabolites 1,25(OH)2D3 and 24,25(OH)2D3 in patients receiving continuous ambulatory peritoneal dialysis (CAPD). The serum concentration of 24,25(OH)2D3 was considerably lower than in hemodialysis patients. The serum concentration of 1,25(OH)2D3 was undetectable an...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183128
更新日期:1984-01-01 00:00:00
abstract::The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188255
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND/AIMS:Diastolic dysfunction (DD) and low levels of thyroid hormones (TH) are frequent found in chronic kidney disease; both are associated with all-cause and cardiovascular mortality. However, a link between them has not yet been established. The aim of this study was to analyze DD as a surrogate marker of fi...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000452342
更新日期:2017-01-01 00:00:00
abstract::Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a new autosomal form of hypophosphatemic rickets, recently described. This disease is characterized, and differs from other forms of hereditary hypophosphatemic rickets and/or osteomalacia by increased serum levels of 1,25-dihydroxyvitamin D, hypercalci...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187029
更新日期:1992-01-01 00:00:00
abstract::A 57-year-old man with renal cell carcinoma associated with membranous glomerulonephropathy (MGN) developed a transient amelioration of the nephrotic syndrome after excision of the tumor. We tried to identify a nephritogenic tumor antigen using the immunoblotting technique in this patient with MGN, since previous stud...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000049047
更新日期:2002-02-01 00:00:00
abstract::An 11-year-old boy developed Kaposi's sarcoma and progressive T lymphocyte deficiency 5 years after cadaveric kidney transplantation for end-stage renal disease. He had received 17 individual red blood cell transfusions prior to and during transplantation in 1980. Human immunodeficiency virus (HIV) was cultured from b...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184458
更新日期:1987-01-01 00:00:00
abstract::In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180720
更新日期:1976-01-01 00:00:00
abstract::A 5-year-old Japanese boy showed nephritis similar to, but distinct from, that in Alport syndrome. Nephrotic syndrome without hematuria was noticed at age 2, although renal biopsy at age 4 revealed widespread irregular thickening of the glomerular basement membrane with splitting of the lamina densa on electron micros...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186136
更新日期:1990-01-01 00:00:00
abstract::The present study was conducted to examine potassium lowering effect of exogenous mineralocorticoid (fludrocortisone acetate; FCA) administration to the patients with chronic renal failure undergoing hemodialysis. Fifteen patients on hemodialysis receiving FCA with its dosage gradually increased from 0 to 0.20 mg/day ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000064116
更新日期:2002-01-01 00:00:00
abstract::An 'epidemic' of aseptic peritonitis occurred in our peritoneal dialysis unit, affecting 5 of 20 patients. Acute and convalescent viral titers were normal in all 5. The peritoneal fluid of the affected patients was not tested for endotoxin, but endotoxin was found in subsequent dialysis fluids from two machines in the...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181728
更新日期:1979-01-01 00:00:00
abstract::A 4-year-old girl, who had been in perfect health, presented with the acute onset of renal failure and abdominal mass. Investigations revealed a solitary left kidney which on histology had the typical features of xanthogranulomatous pyelonephritis. The child had no previous history suggestive of chronic renal disease ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181387
更新日期:1978-01-01 00:00:00