Abstract:
:In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of captopril further enhanced renin secretion, while her blood pressure improved. The patient became normokalemic following tumor removal, and her blood pressure decreased to normal levels with reestablishment of normal circadian blood pressure rhythm. This case demonstrates that, in the absence of renovascular or malignant hypertension, pheochromocytoma can be the underlying cause for the clinical syndrome of hypertension associated with severe hypokalemia and hyperreninemic hyperaldosteronism.
journal_name
Nephronjournal_title
Nephronauthors
Lenz T,Thiede HM,Nussberger J,Atlas SA,Distler A,Schulte KLdoi
10.1159/000187071subject
Has Abstractpub_date
1992-01-01 00:00:00pages
345-50issue
3eissn
1660-8151issn
2235-3186journal_volume
62pub_type
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