Investigations into the effect of glyoxylate decarboxylation and transamination on oxalate formation in the rat.

abstract：:Platelet-activating factor (PAF) belongs to a new class of lipid chemical inflammatory mediators described as acetyl glyceryl ether phosphorylcholine. Although PAF has been implicated in kidney injury, its role in renal immune injury has not been clearly defined yet. We studied the levels of PAF in the plasma and urin...

journal_title：Nephron

authors： Iatrou C,Moustakas G,Antonopoulou S,Demopoulos CA,Ziroyiannis P

更新日期：1996-01-01 00:00:00

abstract：:Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign. We diagnosed Wilson's disease in a 17-year-old male patient 6 years after his first episode of gross hematuria and 2 years after detection of hypercalciuria and nephrocalcinos...

journal_title：Nephron

authors： Hoppe B,Neuhaus T,Superti-Furga A,Forster I,Leumann E

更新日期：1993-01-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：:Nephrotoxic agents such as puromycin aminonucleoside (PAN) and sodium maleate (MAL) have been used to induce experimental glomerular proteinuria and tubular disease, respectively. Current studies show that PAN caused a massive loss of albumin in the urine while not affecting the excretion of the smaller, sex-dependent...

journal_title：Nephron

authors： Neuhaus OW,Flory W,Biswas N,Hollerman CE

更新日期：1981-01-01 00:00:00

abstract：:To clarify the reliability of urinary trehalase activity as a marker of cellular proliferation and/or damage of renal proximal tubules, the activity was examined in healthy newborn infants or infants treated with tobramycin, a drug known as causing tubular cell damage. Eighty-one newborn infants (56 mature infants and...

journal_title：Nephron

authors： Sasai-Takedatsu M,Kojima T,Taketani S,Ono A,Kitamura N,Kobayashi Y

更新日期：1995-01-01 00:00:00

abstract：:A retrospective study of 100 patients followed for 1-4 years after successful renal transplantation was undertaken to assess the amelioration of previously present metabolic bone disease and to determine the risk factors associated with the development of osteonecrosis. 42% of patients showed some evidence of bony abn...

journal_title：Nephron

authors： Gottlieb MN,Stephens MK,Lowrie EG,Griffiths HJ,Kenzora J,Strom TB,Lazarus JM,Tilney NL,Merrill JP

更新日期：1978-01-01 00:00:00

abstract：:Hematuria and proteinuria in rheumatoid arthritis (RA) are commonly associated with drug therapy but occur independently of drugs, amyloid or urologic disorders. The latter occurrences suggest a primary renal lesion associated with RA. Review of reported renal biopsies identifies mesangial glomerulopathy as a common f...

journal_title：Nephron

authors： Pollet S,Depner T,Moore P,Olander H,Robbins D

更新日期：1989-01-01 00:00:00

abstract：:Here, we review the most recent findings on the effects of SARS-CoV-2 infection on kidney diseases, including acute kidney injury, and examine the potential effects of ARBs on the outcomes of patients with COVID-19. Lastly, we discuss the clinical management of COVID-19 patients with existing chronic renal disorders, ...

journal_title：Nephron

authors： Perico L,Benigni A,Remuzzi G

更新日期：2020-01-01 00:00:00

abstract：:A study was undertaken in 24 Chinese patients on maintenance continuous ambulatory peritoneal dialysis, using bezafibrate in its sustained-release form to correct lipid abnormalities. Six patients who received 400 mg/day developed severe muscle weakness with grossly elevated creatine phosphokinase activities within 3 ...

journal_title：Nephron

authors： Chan MK

更新日期：1990-01-01 00:00:00

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：:A 72-year-old non-diabetic uremic woman underwent right nephrectomy for urolithiasis at the age of 50. Because pyuria, fever, chilliness and left flank pain developed during preparing for arteriovenous fistula, she was admitted to National Cheng Kung University Hospital. Renal cell carcinoma (RCC) complicated with emp...

journal_title：Nephron

authors： Lin CH,Huang JJ,Liu HL,Lee SY,Hsieh RY,Tseng CC

更新日期：2002-09-01 00:00:00

abstract：:A 5-year-old Chinese girl had had absence seizures and received sodium valproate (VPA) treatment which provided good control. Six months later, she developed interstitial nephritis with proteinuria and microhematuria. Renal biopsy revealed interstitial nephritis with granular deposition of immunoglobulin G (IgG) and C...

journal_title：Nephron

authors： Lin CY,Chiang H

更新日期：1988-01-01 00:00:00

abstract：:The physicians in charge of 15 German hemodialysis units furnished data on 713 dialysis patients. Data relating to the vocational status were examined for 612 patients aged 60 years or below. It was found that the current working status varies with psychological and social factors. The data show that the vocational st...

journal_title：Nephron

authors： Tews HP,Schreiber WK,Huber W,Zelt J,Ritz E

更新日期：1980-01-01 00:00:00

abstract：:The effect of dilazep, an adenosine potentiator and platelet aggregation inhibitor, on experimental diabetic nephropathy was investigated in spontaneous diabetic Chinese hamster. Prediabetic animals, 8 weeks of age, were divided into two groups. In one group, 5 mg/kg dilazep was injected i.p. once a day. In the other ...

journal_title：Nephron

authors： Morikawa A,Eto M,Makino I

更新日期：1993-01-01 00:00:00

abstract：:A few cases of nephrotic syndrome with the glomerular deposition of an amyloid-like material which did not stain with Congo red have been documented. But extrarenal deposits have not been previously reported in this disease. We describe here a case of nephrotic syndrome associated with the deposition of an amyloid-lik...

journal_title：Nephron

authors： Ozawa K,Yamabe H,Fukushi K,Osawa H,Chiba N,Miyata M,Seino S,Inuma H,Sasaki T,Yoshikawa S

更新日期：1991-01-01 00:00:00

abstract：:Three unusual cases are described which demonstrated hypomagnesemia and symptoms resembling magnesium deficiency syndrome. The hypomagnesemia was most likely secondary to urinary losses from diuresis following release of post-renal obstruction and renal homotransplantation. Heretofore, this association has not been de...

journal_title：Nephron

authors： Davis BB,Preuss HG,Murdaugh HV Jr

更新日期：1975-01-01 00:00:00

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:The role of renal hemodynamic alterations in the curtailment of renal functions was studied in uranyl acetate-induced oliguric (ORF) and nonoliguric (NORF) renal failures of rabbits. 5 days after drug injection, renal functional and morphological changes were most remarkable. A depression of Cin and elevation of serum...

journal_title：Nephron

authors： Sudo M,Honda N,Hishida A,Nagase M

更新日期：1980-01-01 00:00:00

abstract：:A 16-year-old female with acro-renal-ocular syndrome complicated by ventricular septal defect is described. Renal biopsy was performed for the first time in this syndrome, and the results suggested that proteinuria and renal dysfunction were caused by chronic pyelonephritis secondary to malrotation of the kidney and a...

journal_title：Nephron

authors： Naito T,Kida H,Yokoyama H,Abe T,Takeda S,Uno D,Hattori N

更新日期：1989-01-01 00:00:00

abstract：:We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

journal_title：Nephron

authors： Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

更新日期：1985-01-01 00:00:00

abstract：:The Spanish brush goat (Capra hiricus) was studied as an animal model for the anephric state. This rugged animal has a hardy appetite and offers ready blood access for dialysis and sampling. BUN, plasma creatinine and potassium could be brought to normal values by daily hemodialysis. Continual weight loss, severe anem...

journal_title：Nephron

authors： Bower JD,Holbert RD,Pearson JE,Jones Q,Bengis R,Berndt WO

更新日期：1980-01-01 00:00:00

abstract：:Kidney biopsy remains the gold standard for uncovering the pathogenesis of acute and chronic kidney diseases. However, the ability to perform high resolution, quantitative, molecular and cellular interrogation of this precious tissue is still at a developing stage compared to other fields such as oncology. Here, we di...

journal_title：Nephron

authors： Winfree S,Dagher PC,Dunn KW,Eadon MT,Ferkowicz M,Barwinska D,Kelly KJ,Sutton TA,El-Achkar TM

更新日期：2018-01-01 00:00:00

abstract：:We investigated the incidence of painless (silent) myocardial ischemia, manifested as S-T segment deviation, by Holter ECG monitoring in patients with chronic renal failure undergoing regular hemodialysis. Forty-five patients underwent Holter ECG monitoring for a continuous 48-hour period covering dialysis and the int...

journal_title：Nephron

authors： Kremastinos D,Paraskevaidis I,Voudiklari S,Apostolou T,Kyriakides Z,Zirogiannis P,Toutouzas P

更新日期：1992-01-01 00:00:00

abstract：:Using immunofluorescence, we studied 19 patients with IgA nephropathy to determine whether the expression of intercellular adhesion molecule (ICAM)-1 in glomeruli might reflect the disease activity. The relationship between the expression of ICAM-1 and the infiltration of lymphocytes, monocytes and polymorphonuclear l...

journal_title：Nephron

authors： Tomino Y,Ohmuro H,Kuramoto T,Shirato I,Eguchi K,Sakai H,Okumura K,Koide H

更新日期：1994-01-01 00:00:00

abstract：:We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...

journal_title：Nephron

authors： Derbyshire ND,Asscher AW,Matthews PN

更新日期：1989-01-01 00:00:00

abstract：:The study aimed to evaluate the behavior of alpha-glutathione S-transferase (alpha-GST) in the serum of hemodialysis patients with hepatitis C virus (HCV) infection following treatment with high-dose IFN-alpha-2b. Ten patients with detected anti-HCV antibodies and HCV RNA by RT-PCR were selected and treated with high-...

journal_title：Nephron

authors： Boran M,Cetin S

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION/AIMS:The Acute Kidney Injury Network classification is based on small increases in serum creatinine (sCr) for stage 1. This study investigated whether changes in the urinary concentration of neutrophil gelatinase-associated lipocalin (uNGAL) could predict small increases in sCr in patients undergoing coron...

journal_title：Nephron

authors： Souza DF,Reis SS,Botelho RV,Ferreira-Filho SR

更新日期：2015-01-01 00:00:00

abstract：:The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with ...

journal_title：Nephron

authors： von Hartitzsch B,Kerr DN

更新日期：1976-01-01 00:00:00

abstract：:We report a case of rapidly progressive glomerulonephritis due to antiglomerular basement membrane (anti-GBM) antibodies that progressed to end-stage renal disease in a 35-year-old man who used intranasal cocaine on an occasional basis. In contrast to many prior reports of acute renal failure occurring with cocaine-as...

journal_title：Nephron

authors： Peces R,Navascués RA,Baltar J,Seco M,Alvarez J

更新日期：1999-01-01 00:00:00

abstract：:Rat sera, 10-30 h after unilateral nephrectomy (UNI), enhance 3H-thymidine ("3H-Tdr) incorporation into DNA of incubating renal tissue from control rats. Stimulation is even greater when extracts from remaining growing kidneys 20 h after UNI are combined with sera from rats after UNI. UNI extracts, i.e., extracts from...

journal_title：Nephron

authors： Castillo O,Robertson D,Goldin H,Preuss HG

更新日期：1980-01-01 00:00:00