A longitudinal study of bone disease after successful renal transplantation.

Abstract:

:A retrospective study of 100 patients followed for 1-4 years after successful renal transplantation was undertaken to assess the amelioration of previously present metabolic bone disease and to determine the risk factors associated with the development of osteonecrosis. 42% of patients showed some evidence of bony abnormality. Following transplantation, there was slow but progressive resolution in the X-ray changes of hyperparathyroidism but not of osteoporosis. 14% of patients developed osteonecrosis in the posttransplant period with the femoral head the most common site involved (72% of patients). Osteonecrosis could not be related to average steroid dose, number of steroid pulses, or the preexistence of metabolic bone disease.

journal_name

Nephron

journal_title

Nephron

authors

Gottlieb MN,Stephens MK,Lowrie EG,Griffiths HJ,Kenzora J,Strom TB,Lazarus JM,Tilney NL,Merrill JP

doi

10.1159/000181455

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

239-48

issue

1-3

eissn

1660-8151

issn

2235-3186

journal_volume

22

pub_type

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