Serum apolipoproteins A and B, lecithin: cholesterol acyl transferase activities and urinary cholesterol levels in nephrotic syndrome patients before and during steroid treatment.

abstract：BACKGROUND:Sepsis and septic shock are life-threatening causes of acute kidney injury (AKI) frequently seen and managed in intensive care units (ICUs). Sepsis-associated AKI (SA-AKI) independently contributes to the mortality of sepsis. Understanding the potential factors involved in kidney function recovery may furthe...

journal_title：Nephron

authors： Chen JCY,Hu B,Frank RD,Kashani KB

更新日期：2020-01-01 00:00:00

abstract：:The possible role of altered renal prostaglandin metabolism in the generation of post-obstruction diuresis (POD) was examined in 16 adult male Sprague-Dawley rats. Inhibition of cyclooxygenase by the administration of a combination of two nonsteroidal anti-inflammatory drugs (NSAID), meclofenamate and indomethacin in ...

journal_title：Nephron

authors： Kauker ML,Zawada ET

更新日期：1992-01-01 00:00:00

abstract：:Animal models are essential tools to understand the mechanisms underlying the development and progression of renal disease and to study potential therapeutic approaches. Recently, interventional models suitable to induce acute and chronic kidney disease in the mouse have become a focus of interest due to the wide avai...

journal_title：Nephron

authors： Rabe M,Schaefer F

更新日期：2016-01-01 00:00:00

abstract：:Serum and urinary concentrations of NCl, the non collagenous globular domain of collagen IV, were used as markers for turnover of basement membranes. NCl levels were studied in membranous glomerulonephritis and diabetic nephropathy. Thirteen patients with membranous glomerulonephritis and 8 insulin-dependent diabetic ...

journal_title：Nephron

authors： Torffvit O,Agardh CD,Alm P,Wieslander J

更新日期：1991-01-01 00:00:00

abstract：:Interleukin-1 receptor antagonist (IL-1Ra) is a specific inhibitor of interleukin-1 (IL-1). It is structurally similar to IL-1 and binds to IL-1 cell surface receptors, but does not transduce a signal. To examine the relationship between the production of IL-1Ra and IL-1, we incubated peripheral blood mononuclear cell...

journal_title：Nephron

authors： Pereira BJ,King AJ,Falagas ME,Dinarello CA

更新日期：1994-01-01 00:00:00

abstract：:The authors analysed CD4+ subset populations and particularly subset killing in order to evaluate the presence of antilymphocyte antibody against CD4+ subsets in patients with IgA nephropathy (IgA N). This study was performed in 45 patients with IgA N, 30 patients with other forms of glomerulonephritis and 30 healthy ...

journal_title：Nephron

authors： Sato M,Kino K,Nabeshima K,Koshikawa S

更新日期：1992-01-01 00:00:00

abstract：:The role of renal hemodynamic alterations in the curtailment of renal functions was studied in uranyl acetate-induced oliguric (ORF) and nonoliguric (NORF) renal failures of rabbits. 5 days after drug injection, renal functional and morphological changes were most remarkable. A depression of Cin and elevation of serum...

journal_title：Nephron

authors： Sudo M,Honda N,Hishida A,Nagase M

更新日期：1980-01-01 00:00:00

abstract：:Renal biopsy specimens from 8 patients with IgA nephropathy (Berger's disease) were examined immunocytochemically at the light and electron microscopic levels with peroxidase-labeled antibodies to IgA, IgM, J chain and secretory component. In 2 of the 8 specimens heavy deposits of IgA, but no IgM, were found in the me...

journal_title：Nephron

authors： Komatsu N,Nagura H,Watanabe K,Nomoto Y,Kobayashi K

更新日期：1983-01-01 00:00:00

abstract：:In order to assess the effects of sodium depletion on tubular Na and H2O transport in man, renal clearance studies were performed under control conditions and after sodium depletion in 7 normal subjects. The control diet contained 250 mEq of Na daily. Sodium depletion was induced by placing subjects on a 20-mEq/day na...

journal_title：Nephron

authors： DiScala VA,Stein RM

更新日期：1982-01-01 00:00:00

abstract：:Gastrointestinal infection with verotoxin-producing Escherichia coli (VTEC) has been strongly implicated in the etiology of the hemolytic uremic syndrome (HUS), the leading cause of pediatric acute renal failure. The binding of fluorescein-conjugated VT1 overlaid on to frozen human renal sections has been examined. Se...

journal_title：Nephron

authors： Lingwood CA

更新日期：1994-01-01 00:00:00

abstract：:A simple three-pump-based system for the performance of continuous venovenous haemodialysis is described. The method employs access to the circulation via a double-lumen catheter, and by means of a standard extracorporeal peristaltic pump the blood is circulated through a haemofiltration filter. Standard solutions for...

journal_title：Nephron

authors： Møller Jensen D,Bistrup C,Pedersen RS

更新日期：1996-01-01 00:00:00

abstract：:The effect of the antiplatelet agents, ticlopidine and dipyridamole, on nephrotoxic serum nephritis (NTN) was evaluated in rats. An accelerated form of NTN was induced with preimmunization of rabbit IgG 7 days before injection of rabbit antirat nephrotoxic serum. Twelve animals received a peroral dose of 20 mg of ticl...

journal_title：Nephron

authors： Izumino K,Iida H,Asaka M,Sasayama S

更新日期：1987-01-01 00:00:00

abstract：:During the 12 weeks following 5/6 nephrectomy in rats with moderate uremia (creatinine 0.7-1.2 mg/100 ml, BUN 53-89 mg/100 ml), no significant increases in total soft tissue calcification were observed. The calcium concentration of skeletal muscle remained unchanged at 4, 8, and 12 weeks after surgery. A slight but no...

journal_title：Nephron

authors： Ellis KJ,Martino A,Yasumura S,Brook D,Cohn SH,Letteri JM

更新日期：1977-01-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：:Dopexamine hydrochloride is a synthetic dopamine analogue recently developed to improve myocardial and renal performance in patients suffering from low cardiac output states. The present study was designed to assess the pharmacological profile and the anatomical localization of [3H]-dopexamine binding sites within the...

journal_title：Nephron

authors： Napoleone P,Cavallotti C,Ricci A,Amenta F

更新日期：1993-01-01 00:00:00

abstract：:Previous work has shown that cigarette-smoking affects platelets and endothelium in men and women without renal failure. The present study compared 10 male habitual smokers receiving maintenance hemodialysis for chronic renal failure with 11 healthy male habitual smokers before and after controlled cigarette-smoking a...

journal_title：Nephron

authors： Davis JW,Arnold J,Wiegmann T

更新日期：1993-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) is a histological pattern of podocyte and glomerulus injury. FSGS can be primary and secondary to other diseases or due to a genetic cause. Strikingly, genetic causes for adult-onset FSGS are often overlooked, likely because identifying patients with genetic forms of FSGS base...

journal_title：Nephron

authors： Snoek R,Nguyen TQ,van der Zwaag B,van Zuilen AD,Kruis HME,van Gils-Verrij LA,Goldschmeding R,Knoers NVAM,Rookmaaker MB,van Eerde AM

更新日期：2019-01-01 00:00:00

abstract：:Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...

journal_title：Nephron

authors： David-Walek T,Niederstadt C,Rob PM,Fricke L,Latta K,Steinhoff J,Stange EF

更新日期：2001-01-01 00:00:00

abstract：:Recent studies have revealed the potential importance of the extracellular matrix (ECM) in the modulation of mesangial cell (MC) function. Interleukin-6 (IL-6) is produced by MCs and was shown to induce MC proliferation, acting as an autocrine growth factor. Heparin is a known inhibitor of MC proliferation. It was sho...

journal_title：Nephron

authors： Benador NM,Girardin EP

更新日期：1997-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：:HLA antigens of Japanese patients with primary glomerulopathies were determined, and the frequency of each HLA antigen was compared with that of Japanese normal controls. IgA nephropathy with HLA-DR4, idiopathic membraneous glomerulopathy with DR2, lipoid nephrosis with DRw53 and poststreptococcal glomerulonephritis w...

journal_title：Nephron

authors： Naito S,Kohara M,Arakawa K

更新日期：1987-01-01 00:00:00

abstract：:Effect of the immunosuppressive agent, ciclosporin (CS), on bovine serum albumin (BSA) nephritis in rats was evaluated. Eight weeks after immunization, 19 male Wistar rats received a daily intravenous dose of BSA (2 mg). Two weeks later, 11 rats received BSA and an oral dose of CS (10 mg/kg), and 8 rats received only ...

journal_title：Nephron

authors： Fujita M,Iida H,Asaka M,Izumino K,Takata M,Sasayama S

更新日期：1991-01-01 00:00:00

abstract：:Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...

journal_title：Nephron

authors： Venkat Raman G,Pead L,Lee HA,Maskell R

更新日期：1986-01-01 00:00:00

abstract：:To test the hypothesis that acute angiotensin-converting enzyme (ACE) inhibition might predict the postoperative blood pressure outcome, a single oral dose of captopril ranging from 12.5 to 100 mg, was given to 26 patients with renovascular disease and its hypotensive effect was compared with that of surgery (21 patie...

journal_title：Nephron

authors： Salvetti A,Arzilli F,Nuccorini A,Simonini N,Glorioso N,Dessì-Fulgheri P,Madeddu P,Rappelli A

更新日期：1986-01-01 00:00:00

abstract：:Cardiovascular disease remains the major cause of mortality in hemodialysis patients. Abnormal oxidative stress and impaired antioxidant defense may contribute to accelerated atherogenesis associated with uremia. As oxidative modification of lipids appears to be a prerequisite for the development of atherosclerotic le...

journal_title：Nephron

authors： Lim PS,Chan EC,Lu TC,Yu YL,Kuo SY,Wang TH,Wei YH

更新日期：2000-12-01 00:00:00

abstract：:During hemodialysis, platelets are activated across a dialyzer. Soluble P-selectin (sP-selectin) is a form of P-selectin which is a glycoprotein relocated from secretory granules to the surfaces of platelets and endothelial cells after these cells have been physiologically activated. To investigate whether sP-selectin...

journal_title：Nephron

authors： Kawabata K,Nagake Y,Shikata K,Fukuda S,Nakazono H,Takahashi M,Ichikawa H,Makino H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Peritoneal dialysis (PD) is an ideal model for testing remote monitoring (RM). In this study, we evaluated the RM application longitudinally in stable patients undergoing automated PD (APD). METHODS:This was an observational study, comparing outcomes in patients with (current patients) and without (historic...

journal_title：Nephron

authors： Milan Manani S,Rosner MH,Virzì GM,Giuliani A,Berti S,Crepaldi C,Ronco C

更新日期：2019-01-01 00:00:00

abstract：:Rat sera, 10-30 h after unilateral nephrectomy (UNI), enhance 3H-thymidine ("3H-Tdr) incorporation into DNA of incubating renal tissue from control rats. Stimulation is even greater when extracts from remaining growing kidneys 20 h after UNI are combined with sera from rats after UNI. UNI extracts, i.e., extracts from...

journal_title：Nephron

authors： Castillo O,Robertson D,Goldin H,Preuss HG

更新日期：1980-01-01 00:00:00

abstract：:The effects of a high-protein (HP) and low-protein (LP) meal on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and renal vascular resistance (RVR) were examined in conscious dogs. Ingestion of the HP and LP meal produced a temporary increase in systemic hemodynamic parameters due in part to a 'c...

journal_title：Nephron

authors： Zawada ET,Saelens DA,Alavi FK,Lembke JM

更新日期：1994-01-01 00:00:00