Association of class II antigens of HLA with primary glomerulopathies.

abstract：:Rat sera, 10-30 h after unilateral nephrectomy (UNI), enhance 3H-thymidine ("3H-Tdr) incorporation into DNA of incubating renal tissue from control rats. Stimulation is even greater when extracts from remaining growing kidneys 20 h after UNI are combined with sera from rats after UNI. UNI extracts, i.e., extracts from...

journal_title：Nephron

authors： Castillo O,Robertson D,Goldin H,Preuss HG

更新日期：1980-01-01 00:00:00

abstract：:To estimate food sensitization, the human basophil degranulation test (HBDT), usually used for allergy diagnosis, was performed in 34 idiopathic nephrotic syndrome (INS) patients, classified as minimal change glomerular disease, with or without atopic manifestations, and in 19 blood donors; five food allergens (wheat ...

journal_title：Nephron

authors： Lagrue G,Heslan JM,Belghiti D,Sainte-Laudy J,Laurent J

更新日期：1986-01-01 00:00:00

abstract：:Gastrointestinal infection with verotoxin-producing Escherichia coli (VTEC) has been strongly implicated in the etiology of the hemolytic uremic syndrome (HUS), the leading cause of pediatric acute renal failure. The binding of fluorescein-conjugated VT1 overlaid on to frozen human renal sections has been examined. Se...

journal_title：Nephron

authors： Lingwood CA

更新日期：1994-01-01 00:00:00

abstract：:An animal model with experimental uremia is an important research tool for the study of the sequence of pathophysiological events taking place in the uremic syndrome. An appreciable number of animal models and methods for the induction of chronic uremia have been published. It is surprising that no such method has bee...

journal_title：Nephron

authors： Gabizon D,Goren E,Shaked U,Averbukh Z,Rosenmann E,Modai D

更新日期：1985-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:Experiments were conducted which revealed the renal transport mechanism(s) of oxypurines by employing uricosuric agents and pyrazinamide. All specimens being drawn from healthy, normal subjects, the data showed that probenecid increased fractional uric acid, fractional hypoxanthine and fractional xanthine clearance, 3...

journal_title：Nephron

authors： Yamamoto T,Moriwaki Y,Takahashi S,Hada T,Higashino K

更新日期：1988-01-01 00:00:00

abstract：:The relationship between glycosaminoglycans and beta 2-microglobulin, glycosaminoglycans and N-acetyl-beta-D-glucosaminidase as well as the relationship between the chondroitin sulfate/heparan sulfate ratio and SDS electrophoresis in the urine of subjects from the endemic area of Balkan nephropathy was studied in orde...

journal_title：Nephron

authors： Juretić D,Cvoriscec D,Vuković-Holjevac A,Benković J,Lipovac K,Stavljenić A

更新日期：1993-01-01 00:00:00

abstract：:In Wistar rats V-U reflux with distilled water and sterile saline of varying osmolar strength produces scars in the perihilar region of the kidneys in 80% of animals. Using Indian ink as a marker, rupture of the forniceal epithelium regularly followed V-U reflux. Intrapelvic pressure rose to 120 mm Hg during the reflu...

journal_title：Nephron

authors： Morgan M,Asscher AW,Moffat DB

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Evidence indicates that hyperthermia preconditioning (HP) can be protective in kidney transplantation, possibly through increased heat shock protein (HSP) expression. A detailed study about individual HSPs and functional preservation is lacking, however. Therefore, we studied the effects of HP on kidney graf...

journal_title：Nephron

authors： Redaelli CA,Tien YH,Kubulus D,Mazzucchelli L,Schilling MK,Wagner AC

更新日期：2002-04-01 00:00:00

abstract：:15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and p...

journal_title：Nephron

authors： Oh MS,Carroll HJ

更新日期：1978-01-01 00:00:00

abstract：:The efficacy of simvastatin, a competitive inhibitor of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, was investigated in 12 patients treated with continuous ambulatory peritoneal dialysis (CAPD), displaying hypercholesterolemia and moderate hypertriglyceridemia. After a 4-week placebo period, simvastatin was admi...

journal_title：Nephron

authors： Wanner C,Lubrich-Birkner I,Summ O,Wieland H,Schollmeyer P

更新日期：1992-01-01 00:00:00

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：:Thrombospondin (TSP) is a multifunctional glycoprotein that is synthesized by a variety of cells including mesangial cells (MCs). To clarify the effect of TSP on the pathogenesis of diabetic nephropathy, we studied the effect of glucose concentrations on TSP synthesis in cultured human MCs. Thereafter, the effects of ...

journal_title：Nephron

authors： Tada H,Isogai S

更新日期：1998-01-01 00:00:00

abstract：:Propranolol-induced hypoglycemia in hemodialysis patients has been increasingly recognized. We studied the effects of a nonselective beta-blocker (propranolol) and a beta 1-selective-blocker (metoprolol) on glucose metabolism during pharmacologic hyperglucagonemia in these patients. cAMP and insulin responses to gluca...

journal_title：Nephron

authors： Pun KK,Yeung CK,Yeung RT

更新日期：1985-01-01 00:00:00

abstract：:The authors report on the presence of anti-HCV antibodies in a uremic chronic (UC) patient population after 6 months and 1 year with regard to certain selective preventive measures. The nonincreased number of HCV-positive subjects among the UC population could lead to the conclusion that the risk of environmental spre...

journal_title：Nephron

authors： Di Benedetto A,Bilotta E,Minale S,Tritto MC,Russo Spena S,Picardi E,Sorice P

更新日期：1992-01-01 00:00:00

abstract：:Cardiovascular disease is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Epidemiological and clinical studies have shown that this is most frequently related to damage of large conduit arteries. Macrovascular disease develops rapidly in uremic patients and is responsible for ...

journal_title：Nephron

authors： London GM

更新日期：2000-02-01 00:00:00

abstract：:We have previously reported that hyperoxalemia can be aggravated by vitamin C supplementation in regular hemodialysis patients. The present study was undertaken to examine the validity of this observation in an experimental setting. Fifty five-sixths nephrectomized rats were divided into two groups: 30 rats were allow...

journal_title：Nephron

authors： Ono K,Ono H,Ono T,Kikawa K,Oh Y

更新日期：1989-01-01 00:00:00

abstract：:Inflammation is broadly recognized as an important factor in the pathogenesis of acute kidney injury (AKI), but pharmacological approaches to alleviate inflammation in AKI have been without success in clinical trials. Neuromodulation by nonpharmacological methods is emerging as a novel therapeutic strategy to treat in...

journal_title：Nephron

authors： Tanaka S,Inoue T,Hossack JA,Okusa MD

更新日期：2017-01-01 00:00:00

abstract：:We attempted to treat 5 patients on CAPD with fungal peritonitis without removing the catheter. In 1 case, amphotericin B caused a severe chemical peritonitis. The other 4 patients received amphotericin B intravenously and miconazole or flucytosine intraperitoneally. Recovery was obtained in 3 cases without removing t...

journal_title：Nephron

authors： Benevent D,Peyronnet P,Lagarde C,Leroux-Robert C

更新日期：1985-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：:A preparation for performance of renal clearances in the conscious dog is described. The important aspect of the technique is the use of a Pavlov sling and a specially designed restraining apparatus. Of most importance is the use of a 7 French Swan-Ganz balloon-tipped catheter for urinary bladder catheterization. The ...

journal_title：Nephron

authors： Garner D,Laks MM

更新日期：1976-01-01 00:00:00

abstract：:The clinicopathological findings of isolated mesangial C3d deposition in the absence of other complement components or immunoglobulins are summarized. 55 out of 242 individual human renal biopsies examined by immunoperoxidase microscopy had isolated C3d deposition. This group consisted of 12 patients with chronic glom...

journal_title：Nephron

authors： Doi T,Kanatsu K,Suehiro F,Nagai H,Yoshida H,Hamashima Y

更新日期：1987-01-01 00:00:00

abstract：:Lipoproteins might be involved in the pathogenesis of glomerular damage. Uptake of low-density lipoprotein (LDL) by cultured human glomerular cells has been studied using LDL, labelled with the fluorescent probe 1,1'-dioctadecyl-3,3,3'3'-tetramethyl-indocarbocyanine perchlorate (diI). Cells have been characterised usi...

journal_title：Nephron

authors： Rayner HC,Horsburgh T,Brown SL,Lavender FL,Winder AF,Walls J

更新日期：1990-01-01 00:00:00

abstract：:Urate deposits within microtophi were found in 8% of unselected autopsies in Brisbane, Australia. Significant association were demonstrated with (a) a history of gouty arthritis and (b) the existence of nitrogen retention and renal disease of apparently primary, but not gouty, origin. However, in 26% of the patients, ...

journal_title：Nephron

authors： Linnane JW,Burry AF,Emmerson BT

更新日期：1981-01-01 00:00:00

abstract：:The specific lipid alterations in plasma and four different tissues, as well as the activities of plasma lecithin-cholesterol acyltransferase (LCAT) and tissue lipolytic enzymes were determined in experimental nephrotic and control rats. In nephrotic rats, the cholesterol level in the heart was significantly increased...

journal_title：Nephron

authors： Agbedana ED,Yamamoto T,Moriwaki Y,Suda M,Takahashi S,Higashino K

更新日期：1993-01-01 00:00:00

abstract：:To reassess the reported protective effects of verapamil in renal ischaemia, we perfused the left kidney of uninephrectomized female Wistar rats with verapamil (0.1 and 1.0 mg/kg) immediately prior to clamping the renal artery for 60 min. When compared to controls, both doses of verapamil failed to afford protection w...

journal_title：Nephron

authors： Bock HA,Brunner FP,Torhorst J,Thiel G

更新日期：1991-01-01 00:00:00

abstract：:Hyperparathyroidism is a common problem for patients on renal replacement therapy programs. Many long-term dialysis patients require parathyroidectomy while on dialysis. Some patients, however, despite severe renal osteodystrophy, are transplanted, and in these a large proportion show a slow resolution of bony problem...

journal_title：Nephron

authors： Goldsmith D,Owen WJ

更新日期：2001-09-01 00:00:00

abstract：:An 'epidemic' of aseptic peritonitis occurred in our peritoneal dialysis unit, affecting 5 of 20 patients. Acute and convalescent viral titers were normal in all 5. The peritoneal fluid of the affected patients was not tested for endotoxin, but endotoxin was found in subsequent dialysis fluids from two machines in the...

journal_title：Nephron

authors： Gandhi VC,Kamadana MR,Ing TS,Daugirdas JT,Viol GW,Robinson JA,Geis WP,Hano JE

更新日期：1979-01-01 00:00:00

abstract：:Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...

journal_title：Nephron

authors： de Paoli Vitali E,Ricci G,Perini L,Malacarne F,Vedovato M,Guerra G,Dapporto M,Gilli P

更新日期：1996-01-01 00:00:00

abstract：:A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...

journal_title：Nephron

authors： Kelley WN

更新日期：1975-01-01 00:00:00