Urinary glycosaminoglycans in different phases of Balkan endemic nephropathy.

Abstract:

:The relationship between glycosaminoglycans and beta 2-microglobulin, glycosaminoglycans and N-acetyl-beta-D-glucosaminidase as well as the relationship between the chondroitin sulfate/heparan sulfate ratio and SDS electrophoresis in the urine of subjects from the endemic area of Balkan nephropathy was studied in order to establish a method for early detection of this disease. The results show an unquestionable increase in urinary excretion of total glycosaminoglycans in subjects with or suspected of having Balkan endemic nephropathy while the chondroitin sulfate/heparan sulfate ratio was not statistically different between the groups studied. Thus, the chondroitin sulfate/heparan sulfate ratio cannot be used as a cheap and quick semiquantitative method for the diagnosis of early tubular damage in Balkan endemic nephropathy. However, the determination of total glycosaminoglycans in the urine of subjects from endemic areas proved to be valuable additional information helping with the diagnosis of Balkan endemic nephropathy.

journal_name

Nephron

journal_title

Nephron

authors

Juretić D,Cvoriscec D,Vuković-Holjevac A,Benković J,Lipovac K,Stavljenić A

doi

10.1159/000187564

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

564-7

issue

4

eissn

1660-8151

issn

2235-3186

journal_volume

65

pub_type

杂志文章

相关文献

NEPHRON文献大全
  • Renal function impairment in workers previously exposed to cadmium.

    abstract::Cadmium-induced renal effects were followed (1989) in 16 workers previously exposed to cadmium, who had been shown 5 years earlier to have had tubular damage; all but 1 worker had persistent tubular damage (beta 2-microglobulin > 60 micrograms/mmol creatinine). The mean glomerular filtration rate (GFR) decreased from ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187282

    authors: Järup L,Persson B,Edling C,Elinder CG

    更新日期:1993-01-01 00:00:00

  • Comparison between mannitol and saline infusion in HgCl2-induced acute renal failure.

    abstract::The effect of isotonic mannitol and saline in the early phase of mercuric chloride-(HgCl2-)induced acute renal failure (ARF) in the dog was evaluated. During the first 3 h after HgCl2 alone, glomerular filtration rate (GFR) fell from 1.94 +/- 0.14 to 1.04 +/- 0.11 and renal blood flow (RBF) from 13.99 +/- 1.18 to 7.28...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000183307

    authors: Vanholder R,Leusen I,Lameire N

    更新日期:1984-01-01 00:00:00

  • IgA nephropathy. Evaluation of prognostic factors in patients with moderate disease.

    abstract::Previous studies of IgA nephropathy have demonstrated a number of prognostically significant clinical and pathological factors in groups of patients with the full histological spectrum of the disease. Whether these factors can be applied to a group of IgA nephropathy patients with disease of moderate degree is unknown...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000184518

    authors: Magil AB,Ballon HS

    更新日期:1987-01-01 00:00:00

  • Stimulation of polymorphonuclear leukocyte chemotaxis by cold precipitable complexes containing DNA-anti-DNA in active nephritis of systemic lupus erythematosus.

    abstract::DNA-anti-DNA cold precipitable complexes (CPC) isolated from 21 patients with systemic lupus erythematosus were tested for their ability to stimulate polymorphonuclear leukocyte (PMN) chemotaxis and to activate complement in vitro. The complexes activated complement in 20 out of 21 cases and stimulated PMN chemotaxis ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182509

    authors: Losito A,Cecchini C,Pittavini L,Zampi I

    更新日期:1982-01-01 00:00:00

  • Radial artery pseudoaneurysm complicating a Brescia-Cimino dialysis fistula.

    abstract::The authors describe an unusual case of radial artery pseudoaneurysm in a patient with a Brescia-Cimino fistula. Evaluation of a pulsatile mass on the patient's forearm which occurred after hemodialysis led to a nondiagnostic fistulogram. Color flow ultrasound was helpful in identifying the nature of the abnormality, ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000188958

    authors: Labus TP,Trerotola SO,Savader SJ

    更新日期:1996-01-01 00:00:00

  • The role of alpha-glutathione S-transferase in the monitoring of hemodialysis patients with hepatitis C virus infection undergoing high-dose interferon-alpha-2b therapy.

    abstract::The study aimed to evaluate the behavior of alpha-glutathione S-transferase (alpha-GST) in the serum of hemodialysis patients with hepatitis C virus (HCV) infection following treatment with high-dose IFN-alpha-2b. Ten patients with detected anti-HCV antibodies and HCV RNA by RT-PCR were selected and treated with high-...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045363

    authors: Boran M,Cetin S

    更新日期:1999-01-01 00:00:00

  • Renal hemodynamics in oliguric and nonoliguric acute renal failure of rabbits.

    abstract::The role of renal hemodynamic alterations in the curtailment of renal functions was studied in uranyl acetate-induced oliguric (ORF) and nonoliguric (NORF) renal failures of rabbits. 5 days after drug injection, renal functional and morphological changes were most remarkable. A depression of Cin and elevation of serum...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181771

    authors: Sudo M,Honda N,Hishida A,Nagase M

    更新日期:1980-01-01 00:00:00

  • Renal cell carcinoma presenting as nephrotic syndrome.

    abstract::A 64-year-old woman presenting with a history of increasing oedema was found to have nephrotic syndrome with a 24-hour urinary protein excretion of 20.7 g and renal impairment with an initial serum creatinine level of 197 mumol/l (2.16 mg/dl). A renal tumour was demonstrated by ultrasound scanning and subsequent nephr...

    journal_title:Nephron

    pub_type: 杂志文章,评审

    doi:10.1159/000188434

    authors: Woodrow G,Innes A,Ansell ID,Burden RP

    更新日期:1995-01-01 00:00:00

  • Minimal change nephropathy associated with sclerosing mesenteritis.

    abstract::A 65-year-old man with sclerosing mesenteritis developed the nephrotic syndrome. Percutaneous renal biopsy revealed classical histologic findings of minimal change nephropathy with a mild interstitial nephritis. Immunomodulation with prednisone led to a rapid and complete remission of the proteinuria but did not alter...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000189113

    authors: Vernace MA,Bellucci AG,Mossey RT,Susin M,Mailloux LU,Wilkes BM,Katz S,Eskreis D

    更新日期:1996-01-01 00:00:00

  • Potassium depletion potentiates amphotericin-B-induced toxicity to renal tubules.

    abstract::Hypokalemia and potassium depletion are frequent complications of amphotericin B therapy. Both ischemic and gentamicin-induced renal failure is potentiated by potassium depletion; it is, therefore, possible that amphotericin B nephrotoxicity is similarly influenced. This study evaluated whether the acute nephrotoxic r...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000188590

    authors: Bernardo JF,Murakami S,Branch RA,Sabra R

    更新日期:1995-01-01 00:00:00

  • Analysis of urinary albumin excretion in gentamicin-treated rats.

    abstract::Gentamicin doses of 40 mg/kg body weight/day were administered intravenously to 62 Wistar rats. Nineteen animals were also treated orally with an NaHCO3 solution in place of water. The gentamicin-treated animals showed increased albuminuria immediately after the 3rd day of treatment. The fact that this increase was ma...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185043

    authors: Coimbra TM,Lachat JJ

    更新日期:1988-01-01 00:00:00

  • Effect of neutral pH and low-glucose degradation product-containing peritoneal dialysis solution on residual renal function in peritoneal dialysis patients: a meta-analysis.

    abstract:BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

    journal_title:Nephron

    pub_type: 杂志文章,meta分析,评审

    doi:10.1159/000368235

    authors: Wang J,Zhu N,Yuan W

    更新日期:2015-01-01 00:00:00

  • MicroRNA-200a Inhibits Transforming Growth Factor β1-Induced Proximal Tubular Epithelial-Mesenchymal Transition by Targeting β-Catenin.

    abstract:BACKGROUND:The epithelial-mesenchymal transition (EMT) is a crucial event in the development of renal interstitial fibrosis (RIF). A growing body of evidence indicates that β-catenin plays an important role in various types of fibrosis. Although members of the microRNA (miRNA)-200 family have been suggested to suppress...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000479168

    authors: Gong Y,Qin Z,Zhou B,Chen H,Shi Z,Zhang J

    更新日期:2017-01-01 00:00:00

  • Mesangial glomerulopathy and IgM rheumatoid factor in rheumatoid arthritis.

    abstract::Hematuria and proteinuria in rheumatoid arthritis (RA) are commonly associated with drug therapy but occur independently of drugs, amyloid or urologic disorders. The latter occurrences suggest a primary renal lesion associated with RA. Review of reported renal biopsies identifies mesangial glomerulopathy as a common f...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185262

    authors: Pollet S,Depner T,Moore P,Olander H,Robbins D

    更新日期:1989-01-01 00:00:00

  • Effects of chronic sodium depletion on renal tubular sodium and water reabsorption in man.

    abstract::In order to assess the effects of sodium depletion on tubular Na and H2O transport in man, renal clearance studies were performed under control conditions and after sodium depletion in 7 normal subjects. The control diet contained 250 mEq of Na daily. Sodium depletion was induced by placing subjects on a 20-mEq/day na...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182635

    authors: DiScala VA,Stein RM

    更新日期:1982-01-01 00:00:00

  • Effect of hypercalcemia on the anion gap.

    abstract::It has been assumed, but not documented, that hypercalcemia induces an appreciable reduction in the serum anion gap (AG) because it represents an increase in the level of unmeasured cations. To test this question, we retrospectively compared the data of 59 hypercalcemic patients with malignancy [group 1, serum Ca 13.3...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185946

    authors: Oster JR,Gutierrez R,Schlessinger FB,Taylor A,Federman DG,Vaamonde CA

    更新日期:1990-01-01 00:00:00

  • Interstitial nephritis with reversible renal failure due to a copper-containing intrauterine contraceptive device.

    abstract::A 41-year-old woman was admitted to the hospital because of renal failure requiring hemodialysis treatment. Renal biopsy revealed active chronic interstitial nephritis. Renal function nearly normalized after removal of a copper-containing intrauterine device (IUCD). We conclude that copper-IUCDs may lead to renal fail...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000186847

    authors: Hocher B,Keller F,Krause PH,Gollnick H,Oelkers W

    更新日期:1992-01-01 00:00:00

  • Factors influencing the intestinal absorption of calcium and phosphorus following renal transplantation.

    abstract::After successful renal transplantation there is continuing malabsorption of calcium and phosphorus. This is due in part to impaired glomerular filtration rate, and in part to the action of steroid on calcium and phosphorus absorption. The effect of steroids is most marked over the first 18 months after transplantation...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181989

    authors: Walker GS,Peacock M,Marshall DH,Giles GR,Davison AM

    更新日期:1980-01-01 00:00:00

  • Beneficial effect of hemodialysis on renal allograft survival.

    abstract::The effect of the length of hemodialysis on the outcome of renal transplant was evaluated in 43 recipients of renal allograft. 22 out of 23 patients (95.7%) dialyzed for longer than one year had an excellent renal function at one year, while only 10 out of 20 patients (50%) dialyzed for less than one year had good ren...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180475

    authors: Rashid A,Sengar DP,Couture RA,Posen GA,Harris JE

    更新日期:1975-01-01 00:00:00

  • Failure of sodium restriction to abolish exaggerated natriuresis in poststreptococcal glomerulonephritis.

    abstract::Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis. Five patients were studied before and after 1 week of dietary sodium restriction in order to examine the possibility that increased extrac...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180852

    authors: Schacht RG,Steele JM Jr,Lowenstein J,Baldwin DS

    更新日期:1977-01-01 00:00:00

  • Echocardiographic hemodynamic study during ultrafiltration sequential dialysis.

    abstract::4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182448

    authors: Cini G,Camici M,Pentimone F,Palla R

    更新日期:1982-01-01 00:00:00

  • Hemodialysis Patients Display a Declined Proportion of Th2 and Regulatory T Cells in Parallel with a High Interferon-γ Profile.

    abstract:BACKGROUND:A high prevalence of cardiovascular diseases (CVDs) and infections in patients with chronic kidney disease (CKD) arises partly due to a high inflammatory state and aberrations in immune cells function. Following in vitro stimulation of leukocytes with different T-cell mitogens, we observed a lower level of i...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000471814

    authors: Mansouri L,Nopp A,Jacobson SH,Hylander B,Lundahl J

    更新日期:2017-01-01 00:00:00

  • High-renin malignant hypertension secondary to an aldosterone-producing adenoma.

    abstract::Malignant hypertension and high plasma renin activity was found in a 39-year-old woman with an aldosterone-producing adenoma. Only 3 similar cases have been previously reported, and all patients died before or after identification of the adenoma. The present paper documents the first reported case of a successfully ma...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185866

    authors: Ideishi M,Kishikawa K,Kinoshita A,Sasaguri M,Ikeda M,Takebayashi S,Arakawa K

    更新日期:1990-01-01 00:00:00

  • Differences between blood flow as indicated by the hemodialysis blood roller pump and blood flow measured by an ultrasonic sensor.

    abstract:BACKGROUND/AIM:The ultrasonic transit time is currently the best method for measuring the blood flow rate in the extracorporeal hemodialysis circuit. The purpose of this study was to analyze the differences between blood flow as indicated by the hemodialysis blood roller pump (prescribed blood flow) and by an ultrasoni...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045647

    authors: Teruel JL,Fernández Lucas M,Marcén R,Rodríguez JR,López Sánchez J,Rivera M,Liaño F,Ortuño J

    更新日期:2000-06-01 00:00:00

  • Expression of TLR2, NOD1, and NOD2 and the NLRP3 Inflammasome in Renal Tubular Epithelial Cells of Male versus Female Mice.

    abstract:BACKGROUND:Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this is not known. One clue might lie with pattern recognition receptors (PRRs), which are triggers of ischemic i...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000456016

    authors: DeWolf SE,Shigeoka AA,Scheinok A,Kasimsetty SG,Welch AK,McKay DB

    更新日期:2017-01-01 00:00:00

  • Reduced collagenolytic activity of rat kidneys with steptozotocin diabetes.

    abstract::Collagenolytic activity of rat kidneys with streptozotocin diabetes was estimated by means of a biological collagenase assay and compared to healthy controls. Collagenolytic activity was found significantly decreased in rat kidneys with diabetes correlating with blood glucose levels (r = -0.82, p less than 0.001). Ele...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182517

    authors: Lubec G,Leban J,Peyroux J,Sternberg M,Pollak A,Latzka U,Coradello H

    更新日期:1982-01-01 00:00:00

  • Urinary fibrinogen and fibrin fragments in children with renal disease.

    abstract::Fibrinogen fragments (X, Y, D and E) and fibrin fragments (D-dimer and E) were examined in the urine of 52 patients with various types of renal diseases. One or more of the fibrinogen fragments were detectable in all the urine specimens. D-Dimer together with fibrinogen fragments was found in 38 of the 52 patients. Th...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182833

    authors: Yoshioka K,Iseki T,Akano N,Uraoka Y,Miyata H,Maki S

    更新日期:1982-01-01 00:00:00

  • Membranous glomerulonephritis associated with renal cell carcinoma: failure to detect a nephritogenic tumor antigen.

    abstract::A 57-year-old man with renal cell carcinoma associated with membranous glomerulonephropathy (MGN) developed a transient amelioration of the nephrotic syndrome after excision of the tumor. We tried to identify a nephritogenic tumor antigen using the immunoblotting technique in this patient with MGN, since previous stud...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000049047

    authors: Togawa A,Yamamoto T,Suzuki H,Watanabe K,Matsui K,Nagase M,Hishida A

    更新日期:2002-02-01 00:00:00

  • Combined chemotherapy and radiotherapy for esophageal carcinoma in a hemodialyzed patient. Long-term survival.

    abstract::The use of antimitotic chemotherapy in hemodialysis patients is not yet well codified, and each individual decision remains difficult. We report the case of a 68-year-old hemodialyzed man who developed a squamous cell carcinoma of the upper third of the esophagus. Necessarily disabling surgery was rejected, and three ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000189461

    authors: Rebibou JM,Chauffert B,Dumas M,Mousson C,Bone MC,Tanter Y,Rifle G

    更新日期:1996-01-01 00:00:00

  • Effect of dialysate calcium concentration on plasma parathyroid hormone during hemodialysis.

    abstract::The effect of changes in the dialysate calcium concentration on calcium fractions and parathyroid hormone species in plasma during hemodialysis has been examined. C-terminal immunoreactive parathyroid hormone was suppressed when plasma calcium increased by greater than 25% whereas N-terminal fragments demonstrated an ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180870

    authors: McIntosh CH,Fuchs C,Dorn D,Quellhorst E,Henning HV,Hesch RD,Scheler F

    更新日期:1977-01-01 00:00:00