Abstract:
:The effect of the length of hemodialysis on the outcome of renal transplant was evaluated in 43 recipients of renal allograft. 22 out of 23 patients (95.7%) dialyzed for longer than one year had an excellent renal function at one year, while only 10 out of 20 patients (50%) dialyzed for less than one year had good renal function at one year. Only one kidney (4.3%) was lost due to rejection in the first group, while 10 kidneys (50%) failed to function because of severe rejection in the second group. The length of hemodialysis appears to have a beneficial effect on graft survival, but the mechanism by which it exerts this effect is not clear.
journal_name
Nephronjournal_title
Nephronauthors
Rashid A,Sengar DP,Couture RA,Posen GA,Harris JEdoi
10.1159/000180475subject
Has Abstractpub_date
1975-01-01 00:00:00pages
413-20issue
6eissn
1660-8151issn
2235-3186journal_volume
14pub_type
杂志文章相关文献
NEPHRON文献大全abstract:BACKGROUND/AIMS:Glomerular basement membrane (GBM) thickening and mesangial matrix expansion are characteristic features of diabetic nephropathy. The present study investigates the role of endothelins (ETs) in the pathogenesis of such changes in diabetic nephropathy. METHODS:Diabetic (streptozotocin-induced, 65 mg/kg)...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000046319
更新日期:2002-01-01 00:00:00
abstract::Tissue fluid and plasma oncotic pressure levels were measured in an unselected group of 13 patients presenting with congestive heart failure. Patients had a mean serum albumin of 3.6 g/dl +/- (SD) 0.35; serum oncotic pressure was 22.23 +/- 1.8 mm Hg; tissue fluid (lower leg) oncotic pressure was 0.985 +/- 0.34 mm Hg. ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185804
更新日期:1990-01-01 00:00:00
abstract::Diabetic nephropathy (DN), a distinct manifestation of diabetic kidney disease, affects approximately 30% of patients with diabetes. While most attention has been focused on glomerular changes related to DN, there is growing evidence that tubulopathy is a key feature in the pathogenesis of this disease. The renal prox...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000494512
更新日期:2019-01-01 00:00:00
abstract::Computerized tomography (CT) has the advantage of allowing the isolation of trabecular bone of the axial skeleton, which is the more sensitive to metabolic changes. By means of single-energy X-ray CT we have devised a method for assessing trabecular bone mass (TBM) at L-4 vertebral body, which has an acceptable reprod...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184007
更新日期:1986-01-01 00:00:00
abstract::The urinary transforming growth factor beta (TGF-beta) excretion was measured in 33 patients including 10 with systemic lupus erythematosus (SLE), 8 with focal glomerular sclerosis (FGS), 9 with IgA nephropathy (IgAN), and 6 with membranous nephropathy (MN), and in 7 healthy subjects by enzyme-linked immunosorbent ass...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187852
更新日期:1994-01-01 00:00:00
abstract::Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000184011
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Acid-base disturbances are frequent in critically ill patients. Arterial blood gas (ABG) is the gold standard in the diagnosis of these disturbances, but it is invasive with potential hazards. For patients with a central venous catheter, venous blood gas (VBG) sampling may be an alternative, less-invasive di...
journal_title:Nephron
pub_type: 杂志文章,多中心研究
doi:10.1159/000488501
更新日期:2018-01-01 00:00:00
abstract:CONTEXT:The widespread use of diuretics, potassium supplements, and medications that block renin angiotensin system puts the chronic kidney disease (CKD) population at high risk for dyskalemia, both hyperkalemia and hypokalemia. The optimal potassium level in a CKD patient is unknown. Subject of review: Two recent stud...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000490008
更新日期:2018-01-01 00:00:00
abstract::A few cases of nephrotic syndrome with the glomerular deposition of an amyloid-like material which did not stain with Congo red have been documented. But extrarenal deposits have not been previously reported in this disease. We describe here a case of nephrotic syndrome associated with the deposition of an amyloid-lik...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186449
更新日期:1991-01-01 00:00:00
abstract::The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186478
更新日期:1991-01-01 00:00:00
abstract::Methylguanidine (MG), guanidinosuccinic acid (GSA) and creatinine (Cr), which accumulate in the body in parallel with the progress of renal failure after adenine administration, were given separately to rats in order to compare their toxicities. Food containing adenine was given to rats for 24 days to induce renal fai...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185328
更新日期:1989-01-01 00:00:00
abstract::We reviewed the recommendations and outcomes for all patients with diabetes mellitus and end-stage renal disease referred to the Medical Center Hospital of Vermont from 1971 through December 1983. During this period, we recommended transplantation in 53 of 73 patients evaluated. Thirty-two transplants were performed i...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183693
更新日期:1986-01-01 00:00:00
abstract::An animal model with experimental uremia is an important research tool for the study of the sequence of pathophysiological events taking place in the uremic syndrome. An appreciable number of animal models and methods for the induction of chronic uremia have been published. It is surprising that no such method has bee...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183491
更新日期:1985-01-01 00:00:00
abstract::In 2014 57.5% of HD patients and 62.7% of PD patients achieved the audit measure for phosphate. 29.0% of HD and 30.3% of PD patients had a serum phosphate above the audit standard range. 79.1% of HD and 79.7% of PD patients had adjusted calcium between 2.2–2.5 mmol/L. 57.4% of HD and 65.0% of PD patients had a serum P...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000444823
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000453005
更新日期:2017-01-01 00:00:00
abstract::Hyaluronic acid (HA) is a ubiquitous component of extracellular matrix. After tissue injury, HA appears in greater abundance during the inflammatory response and the phase of clearance of cell and matrix debris, before collagen production and matrix degradation. The aim of this study was to examine whether normal rat ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000046019
更新日期:2001-08-01 00:00:00
abstract::Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...
journal_title:Nephron
pub_type: 社论
doi:10.1159/000186434
更新日期:1991-01-01 00:00:00
abstract::The techniques of bonding of anionic antibiotics by treatment with cationic surfactants were applied to continuous ambulatory peritoneal dialysis (CAPD) catheters. The elution of 14C-penicillin from tridodecylmethylammonium chloride (TDMAC) treated silicone elastomer catheters in dialysis solution was biphasic, with 9...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184366
更新日期:1987-01-01 00:00:00
abstract::The methodology for the collection, extraction, separation and measurement of urinary angiotensin II [the octapeptide, ANG(1-8)] is described. To determine the origin of urinary ANG(1-8), mean arterial pressure, renal hemodynamics and the arterial, renal venous and urinary concentrations of ANG(1-8) were examined prio...
journal_title:Nephron
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000188215
更新日期:1994-01-01 00:00:00
abstract::Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000501639
更新日期:2019-01-01 00:00:00
abstract::Serum leptin concentrations in normal humans have been reported to correlate with the body mass index (BMI) as well as with the body fat mass. In this study, we measured serum leptin concentrations in 107 patients on hemodialysis, 30 of whom had diabetes mellitus as the cause, and examined the clinical significance. F...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045122
更新日期:1998-09-01 00:00:00
abstract::The present study was conducted to examine potassium lowering effect of exogenous mineralocorticoid (fludrocortisone acetate; FCA) administration to the patients with chronic renal failure undergoing hemodialysis. Fifteen patients on hemodialysis receiving FCA with its dosage gradually increased from 0 to 0.20 mg/day ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000064116
更新日期:2002-01-01 00:00:00
abstract::In kidney allografts, focal segmental glomerulosclerosis (FSGS) has been described as recurrent, de novo, or a histological variant of chronic transplant glomerulopathy. We describe a unique case of de novo FSGS in a renal transplant not accompanied by any feature of rejection in a patient who had not been immunosuppr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045412
更新日期:1999-01-01 00:00:00
abstract::We investigated the incidence of painless (silent) myocardial ischemia, manifested as S-T segment deviation, by Holter ECG monitoring in patients with chronic renal failure undergoing regular hemodialysis. Forty-five patients underwent Holter ECG monitoring for a continuous 48-hour period covering dialysis and the int...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186733
更新日期:1992-01-01 00:00:00
abstract::A 72-year-old non-diabetic uremic woman underwent right nephrectomy for urolithiasis at the age of 50. Because pyuria, fever, chilliness and left flank pain developed during preparing for arteriovenous fistula, she was admitted to National Cheng Kung University Hospital. Renal cell carcinoma (RCC) complicated with emp...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000064452
更新日期:2002-09-01 00:00:00
abstract::Because of the great problem of viral hepatitis in hemodialysis patients, the Italian Society of Nephrology decided to perform a national epidemiologic survey. We contacted 467 nephrological centers by a questionnaire which let us have information on 25,746 uremic patients: 18,338 on HD, 2,250 on PD and 5,176 with kid...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186905
更新日期:1992-01-01 00:00:00
abstract::We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185586
更新日期:1989-01-01 00:00:00
abstract::We investigated changes in the levels of mRNA transcripts encoding types I and IV collagen in the kidney following the administration of ciclosporin (CS) in mice. Daily doses of CS increased the levels of mRNAs encoding collagen types I and IV in whole kidneys harvested 4 weeks after treatment. At this time point, nei...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186710
更新日期:1992-01-01 00:00:00
abstract::A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia in the lower extremities and elevated serum aminotransferase levels. His viral markers and other factors that may cause myal...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000065439
更新日期:2002-12-01 00:00:00
abstract::In earlier studies, we have shown that induction of passive Heymann nephritis (PHN) by intrarenal infusion of anti-Fx1A antibodies provokes an immediate fall in renal blood flow (RBF) and glomerular filtration rate (GFR). This was probably mediated via the complement system, as infusion of the F(ab')2 fraction of anti...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186808
更新日期:1992-01-01 00:00:00