Renal cell carcinoma complicated by emphysematous pyelonephritis in a non-diabetic patient with renal failure.

Abstract:

:A 72-year-old non-diabetic uremic woman underwent right nephrectomy for urolithiasis at the age of 50. Because pyuria, fever, chilliness and left flank pain developed during preparing for arteriovenous fistula, she was admitted to National Cheng Kung University Hospital. Renal cell carcinoma (RCC) complicated with emphysematous pyelonephritis (EPN) was diagnosed and immediately treated with antibiotics and CT-guided percutaneous catheter drainage. Cultures of pus and blood yielded Escherichia coli. She received left radical nephrectomy later for the control of persistent sepsis and removal of left renal tumor. The pathology of the tumor was composed of a glandular arrangement of granular cells with the occasional atypism, and renal parenchyma had been totally replaced by RCC. The non-tumor part of the kidney showed chronic pyelonephritis. Five months later, multiple metastases developed. We reported this first uremic case with EPN and RCC, but without diabetes mellitus and urinary tract obstruction. The gas formation may be due to large RCC, which caused impaired tissue perfusion and E. coli infection.

journal_name

Nephron

journal_title

Nephron

authors

Lin CH,Huang JJ,Liu HL,Lee SY,Hsieh RY,Tseng CC

doi

10.1159/000064452

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

227-9

issue

1

eissn

1660-8151

issn

2235-3186

pii

nef92227

journal_volume

92

pub_type

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