Abstract:
:A 65-year-old man with sclerosing mesenteritis developed the nephrotic syndrome. Percutaneous renal biopsy revealed classical histologic findings of minimal change nephropathy with a mild interstitial nephritis. Immunomodulation with prednisone led to a rapid and complete remission of the proteinuria but did not alter the course of the underlying sclerosing mesenteritis. The association of lymphomatous and nonlymphomatous neoplasms with minimal change nephropathy has been well-described. Our review of the literature indicates a parallel association of malignant lymphoma with sclerosing mesenteritis and a variety of disorders that constitute a spectrum of disease. The occurrence of this histopathologic form of renal injury and therapeutic response in the setting of a known lymphoreticular disorder suggests a role for a generalized alteration in cell-mediated immunity and not a tumor-induced elaboration of a factor(s) that directly damages the glomerular filtration barrier.
journal_name
Nephronjournal_title
Nephronauthors
Vernace MA,Bellucci AG,Mossey RT,Susin M,Mailloux LU,Wilkes BM,Katz S,Eskreis Ddoi
10.1159/000189113subject
Has Abstractpub_date
1996-01-01 00:00:00pages
473-6issue
3eissn
1660-8151issn
2235-3186journal_volume
73pub_type
杂志文章相关文献
NEPHRON文献大全abstract:BACKGROUND/AIM:Our previous study with prevalent cases suggested that some genetic, immunological and lifestyle-related factors increased the risk of immunoglobulin A nephropathy (IgAN). To confirm this hypothesis, we conducted another case-control study. METHODS:The study included 116 incident cases and 276 sex-, age...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000046309
更新日期:2002-01-01 00:00:00
abstract::A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia in the lower extremities and elevated serum aminotransferase levels. His viral markers and other factors that may cause myal...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000065439
更新日期:2002-12-01 00:00:00
abstract::The effect of treatment with 1 alpha-hydroxycholecalciferol (1 alpha-OH-D3) and different diets on uremic arterial disease was studied. Three groups of rabbits with chronic renal failure (CRF) were kept on three diets with a low, medium or high content of calcium and phosphate. Half the rabbits in each group were trea...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183007
更新日期:1983-01-01 00:00:00
abstract::The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186478
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To develop and internally validate a multivariable prediction model based on simple clinical record data and laboratory tests and to estimate the probability of left-ventricular diastolic dysfunction (LVDD) in stable maintenance hemodialysis (MHD) patients without clinical heart failure. DESIGN:Cross-section...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000499605
更新日期:2019-01-01 00:00:00
abstract::Chyloperitoneum is a rare condition in patients undergoing peritoneal dialysis. We report here a patient who developed chylous ascites during the course of tuberculous peritonitis. The diagnosis was confirmed by cultures of dialysate and peritoneal biopsy, and laparoscopy revealed severe hyperemia and intestine adhesi...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188969
更新日期:1996-01-01 00:00:00
abstract::A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187061
更新日期:1992-01-01 00:00:00
abstract::Efficacy and safety of a low-molecular-weight heparin (LMWH) were studied in 33 stable maintenance hemodialysis patients who had a bleeding tendency on unfractionated heparin. The optimal dose of LMWH for each patient was titrated before the study; the mean total LMWH dosage was 1,152 +/- 574 IU. No major bleeding or ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000045840
更新日期:2000-12-01 00:00:00
abstract::This study aims to raise the possibility of methylguanidine, a peroxidative product of creatinine, as a measure of the peroxidative state. As a known standard, we measured the inhibitory effect of uremic serum on the NADPH-dependent microsomal lipid peroxidation. This is an established method for evaluating the peroxi...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189451
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. METHODS:A home hemodialysis program was started in November 1998 in the University of Torino, Italy (2...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000063319
更新日期:2002-10-01 00:00:00
abstract::Severe erythrocytosis is associated with increased whole blood viscosity and impaired blood flow. Since a reduced blood flow will cause tissue hypoxia and since tissue hypoxia is associated with increased synthesis of erythropoietin, erythrocytosis per se should cause an increase in the rate of red cell production. Th...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183585
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Previous studies showed that ceftriaxone can cause acute kidney injury (AKI) in the pediatric population. This study proposed a cellular model of crystalline nephropathy in ceftriaxone-associated AKI and explored the related pathophysiology by using a proteomic approach. METHODS:Ceftriaxone was crystallized...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000486324
更新日期:2018-01-01 00:00:00
abstract::In kidney allografts, focal segmental glomerulosclerosis (FSGS) has been described as recurrent, de novo, or a histological variant of chronic transplant glomerulopathy. We describe a unique case of de novo FSGS in a renal transplant not accompanied by any feature of rejection in a patient who had not been immunosuppr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045412
更新日期:1999-01-01 00:00:00
abstract::The purpose of this study was to characterize renal cell carcinoma tissue by the measurement of microacoustic properties. A scanning acoustic microscope system operating in the frequency range of 100-200 MHz was employed and the attenuation constant and sound speed were measured on the two-dimensional distribution. Th...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189291
更新日期:1996-01-01 00:00:00
abstract::Assessment of kidney function is primarily based on urine output and Creatinine (Cr)-based methods to estimate glomerular filtration rate (GFR). The latter is confounded as Cr is not exclusively filtered by the kidney and rises relatively late after the onset of acute kidney injury (AKI). This leads to delays in recog...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000509352
更新日期:2020-01-01 00:00:00
abstract::Pulmonary calcifications are known to occur in patients with chronic renal failure. Recently, scintigrams with bone-seeking radionuclides have been used to detect subclinical pulmonary calcium deposits. We studied 18 children on maintenance dialysis without evidence of pulmonary calcification on chest X-ray. Four chil...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183911
更新日期:1986-01-01 00:00:00
abstract::Inflammation is broadly recognized as an important factor in the pathogenesis of acute kidney injury (AKI), but pharmacological approaches to alleviate inflammation in AKI have been without success in clinical trials. Neuromodulation by nonpharmacological methods is emerging as a novel therapeutic strategy to treat in...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000477218
更新日期:2017-01-01 00:00:00
abstract::The concentration changes, during hemodialysis treatment, of 18 characteristic uremia compounds, analyzed by high-pressure liquid chromatography in sera of renal patients were studied. Pre- to postdialysis concentration ratios (dialysis ratio, D) varied from 0.83 to 3.04 for the different solutes. A division into thre...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185746
更新日期:1989-01-01 00:00:00
abstract::Clearance and in vitro microperfusion studies were performed in rabbits to determine the effect of cisplatin on proximal straight tubule transport of calcium and magnesium. Rabbits were injected with cisplatin (2.5 mg/kg i.p. once weekly) for 3 weeks, whereas control rabbits received normal saline solution which serve...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184988
更新日期:1988-01-01 00:00:00
abstract::To verify the action of heparin on peritoneal transport, we selected 20 patients on acute peritoneal dialysis and performed two 2-hour cycles with 2,000 cm3 of a 1.5% solution, adding 2,000 units of heparin to the second cycle. The patients were also randomized into 2 groups: group A, adding 1.5 mg gentamycin/kg to th...
journal_title:Nephron
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000183336
更新日期:1985-01-01 00:00:00
abstract::X-linked nephrogenic diabetes insipidus (NDI) is a rare disease caused by mutations in the vasopressin V2 receptor (AVPR2) gene. We analyzed the AVPR2 gene in 6 unrelated Korean families with X-linked NDI, and found 6 novel mutations. Two of them were missense point mutations, 2 were short deletions causing frameshift...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189581
更新日期:1997-01-01 00:00:00
abstract::In 25 patients with nephrotic syndromes of different origin, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion. This effect of indomethacin on GFR and proteinuria was more pronounced when the renin-angiotensin system was stimulated by a low-sodium diet and 50 m...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181478
更新日期:1978-01-01 00:00:00
abstract::Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000182055
更新日期:1981-01-01 00:00:00
abstract::A 64-year-old woman presenting with a history of increasing oedema was found to have nephrotic syndrome with a 24-hour urinary protein excretion of 20.7 g and renal impairment with an initial serum creatinine level of 197 mumol/l (2.16 mg/dl). A renal tumour was demonstrated by ultrasound scanning and subsequent nephr...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000188434
更新日期:1995-01-01 00:00:00
abstract::The study aimed to evaluate the behavior of alpha-glutathione S-transferase (alpha-GST) in the serum of hemodialysis patients with hepatitis C virus (HCV) infection following treatment with high-dose IFN-alpha-2b. Ten patients with detected anti-HCV antibodies and HCV RNA by RT-PCR were selected and treated with high-...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000045363
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000453005
更新日期:2017-01-01 00:00:00
abstract::During hemodialysis therapy, a large amount of water is removed from the patient's blood in a short time; however, blood pressure remains stable in most patients. As water is removed, the circulating serum proteins become more concentrated, resulting in a marked increase in the driving force which pulls water from the...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189320
更新日期:1996-01-01 00:00:00
abstract::The effects of each of several tannins purified from Rhei Rhizoma on serum constituents were investigated in rats with adenine-induced renal failure. Blood levels of urea nitrogen, methylguanidine (MG), and guanidinosuccinic acid (GSA) were significantly decreased in rats given (-)-epicatechin 3-O-gallate at a dose of...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186406
更新日期:1991-01-01 00:00:00
abstract::Pruritus is a common symptom among patients undergoing long-term hemodialysis. However, its etiology remains unclear. In an attempt to clarify its cause we tried to correlate pruritus and its intensity with several serological variables in 94 hemodialysis patients. Our results show that higher serum aluminum concentra...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000189499
更新日期:1997-01-01 00:00:00
abstract::ExHC rats were bred from the Sprague-Dawley strain and are highly susceptible to dietary hypercholesterolemic stimuli. Although chemical and histological examination of the aorta from ExHC rats fed a diet containing 3% cholesterol, 0.6% sodium cholate and 15% olive oil (high-cholesterol diet, HCD) has been reported, r...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187216
更新日期:1993-01-01 00:00:00