Abstract:
:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal fluorescein angiography did not demonstrate diabetic retinopathy. The kidney biopsy showed nodular diabetic nephropathy, with increased mesangial matrix, thickened glomerular basement membrane, and afferent and efferent glomerular arteriolar hyalinization. The diagnosis of nodular diabetic nephropathy was made in this patient in the absence of past or present or familial evidence of diabetes mellitus.
journal_name
Nephronjournal_title
Nephronauthors
da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig Idoi
10.1159/000187061subject
Has Abstractpub_date
1992-01-01 00:00:00pages
289-91issue
3eissn
1660-8151issn
2235-3186journal_volume
62pub_type
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