Reversible uremia and its effect on the glomerular filtration rate.

abstract：BACKGROUND/AIMS:Renal function deteriorates with age, but a few studies have addressed this longitudinally in elderly women. Our objective was, using 5 estimated glomerular filtration rates (eGFR)-equations, to evaluate changes in renal function and association with adverse outcomes for a decade in 75-year-old women. ...

journal_title：Nephron

authors： Malmgren L,McGuigan FE,Berglundh S,Westman K,Christensson A,Åkesson K

更新日期：2015-01-01 00:00:00

abstract：:A critical survey of the literature suggests that elevated serum uric acid is definitely associated with hypertension and may function as an independent risk factor in the development of this disease. The possible role of an elevated serum uric acid as an independent risk factor for the development of ischemic heart d...

journal_title：Nephron

authors： Tweeddale MG,Fodor JG

更新日期：1979-01-01 00:00:00

abstract：:A 5-year-old Japanese boy showed nephritis similar to, but distinct from, that in Alport syndrome. Nephrotic syndrome without hematuria was noticed at age 2, although renal biopsy at age 4 revealed widespread irregular thickening of the glomerular basement membrane with splitting of the lamina densa on electron micros...

journal_title：Nephron

authors： Kawakami H,Murakami T,Murano I,Ushijima T,Taguchi T,Hattori S,Kajii T

更新日期：1990-01-01 00:00:00

abstract：:We investigated the incidence of painless (silent) myocardial ischemia, manifested as S-T segment deviation, by Holter ECG monitoring in patients with chronic renal failure undergoing regular hemodialysis. Forty-five patients underwent Holter ECG monitoring for a continuous 48-hour period covering dialysis and the int...

journal_title：Nephron

authors： Kremastinos D,Paraskevaidis I,Voudiklari S,Apostolou T,Kyriakides Z,Zirogiannis P,Toutouzas P

更新日期：1992-01-01 00:00:00

abstract：:In the present study, activity of polymorphonuclear leukocyte (PMNL) intracellular antioxidant enzymes, i.e. catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX), was assessed in CRF patients on hemodialysis (HD), or continuous ambulatory peritoneal dialysis (CAPD) and in healthy controls. The activit...

journal_title：Nephron

authors： Shurtz-Swirski R,Mashiach E,Kristal B,Shkolnik T,Shasha SM

更新日期：1995-01-01 00:00:00

abstract：:The methodology for the collection, extraction, separation and measurement of urinary angiotensin II [the octapeptide, ANG(1-8)] is described. To determine the origin of urinary ANG(1-8), mean arterial pressure, renal hemodynamics and the arterial, renal venous and urinary concentrations of ANG(1-8) were examined prio...

journal_title：Nephron

authors： Reams G,Villarreal D,Wu Z,Bauer JH

更新日期：1994-01-01 00:00:00

abstract：:The accumulation in blood plasma and efficiency of hemodialysis of pyrimidine compounds (orotic acid, orotidine, pseudouridine, uridine, thymine) as well as uric acid and creatinine in 23 patients with chronic renal failure (CRF) was investigated. As a reference, the analysis of the above metabolites in the plasma of ...

journal_title：Nephron

authors： Daniewska-Michalska D,Motyl T,Gellert R,Kukulska W,Podgurniak M,Opechowska-Pacocha E,Ostrowski K

更新日期：1993-01-01 00:00:00

abstract：:15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and p...

journal_title：Nephron

authors： Oh MS,Carroll HJ

更新日期：1978-01-01 00:00:00

abstract：:We encountered 11 patients with aluminum-associated bone disease (AABD), and treated them with deferoxamine (DFO). In 3 patients, a second bone biopsy was done during DFO treatment. Clinical features of AABD were compared with surgically proven secondary hyperparathyroidism (2 degrees HPT) with osteitis fibrosa on X-r...

journal_title：Nephron

authors： Iwamoto N,Ono T,Yamazaki S,Fukuda T,Kondo M,Yamamoto N,Hiratake Y,Masugi Y,Kubo Y,Hino M

更新日期：1986-01-01 00:00:00

abstract：:Glomerular morphological changes produced by 5-hour intravenous infusion of endotoxin (40 micrograms/kg/h) were studied in 57 rabbits. During endotoxin infusion all animals developed signs of endotoxemia, anemia, and transient leukopenia and thrombocytopenia. Acute renal failure also developed in all animals. By light...

journal_title：Nephron

authors： Bertani T,Abbate M,Zoja C,Corna D,Remuzzi G

更新日期：1989-01-01 00:00:00

abstract：:A previously described method for recovering a proximal renal tubular epitheal antigen (HRTE-1) from normal human kidney was modified by using ion-exchange and immunoaffinity chromatography in order to create easily reproducible conditions for antigen isolation. Radioiodinated HRTE-1 was then used to establish a 3-hou...

journal_title：Nephron

authors： Zager RA,Rubin NT,Ebert T,Maslov N

更新日期：1980-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:The clinical profile of a patient with a 15 years' evolution of acne conglobata developing systemic amyloidosis with severe renal involvement is described, and the possible influence of suppurative skin foci surgical excision on the rapid progression to terminal renal failure is discussed. This etiological cause of se...

journal_title：Nephron

authors： Naya MT,Soria C,Quereda C,Orte L,Romero R,Ortuño J

更新日期：1991-01-01 00:00:00

abstract：:We conducted a retrospective study with 750 peritoneal dialysis (PD) patients in a Spanish multicenter registry between 1993 and 1999 to analyze comorbidity and mortality in type 1 diabetes (T1D), type 2 diabetes (T2D) and nondiabetic (ND) patients. 163 patients (21.7%) were diabetic--96 T1D (58.8%) and 67 T2D (42.2%)...

journal_title：Nephron

authors： Miguel A,García-Ramón R,Pérez-Contreras J,Gómez-Roldán C,Alvariño J,Escobedo J,García H,Lanuza M,López-Menchero R,Olivares J,Tornero F,Albero D,Levante PD Multicenter group.

更新日期：2002-03-01 00:00:00

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:329 patients were evaluated from 1978 to 1990. 40 new cases of non-A non-B hepatitis were observed, all regarding patients on hemodialysis. Since the beginning of 1989, we introduced measures to limit the diffusion of the virus: reduction to a minimum of blood transfusions and a new disinfection protocol for monitors,...

journal_title：Nephron

authors： La Russa A,Bufano G,Cauzzi L,Pecchini P

更新日期：1992-01-01 00:00:00

abstract：:It is unknown whether continuous renal replacement techniques result in diminished morbidity and mortality when compared to conventional dialytic techniques. To investigate this issue a previously described, retrospectively studied group of critically ill patients with severe acute renal failure treated by conventiona...

journal_title：Nephron

authors： Bellomo R,Farmer M,Parkin G,Wright C,Boyce N

更新日期：1995-01-01 00:00:00

abstract：:The effect of the length of hemodialysis on the outcome of renal transplant was evaluated in 43 recipients of renal allograft. 22 out of 23 patients (95.7%) dialyzed for longer than one year had an excellent renal function at one year, while only 10 out of 20 patients (50%) dialyzed for less than one year had good ren...

journal_title：Nephron

authors： Rashid A,Sengar DP,Couture RA,Posen GA,Harris JE

更新日期：1975-01-01 00:00:00

abstract：:The effect of the antiplatelet agents, ticlopidine and dipyridamole, on nephrotoxic serum nephritis (NTN) was evaluated in rats. An accelerated form of NTN was induced with preimmunization of rabbit IgG 7 days before injection of rabbit antirat nephrotoxic serum. Twelve animals received a peroral dose of 20 mg of ticl...

journal_title：Nephron

authors： Izumino K,Iida H,Asaka M,Sasayama S

更新日期：1987-01-01 00:00:00

abstract：:The glomerular mesangium is an important site of activity in patients with heroin addiction. We studied the effect of morphine, a metabolite of heroin, on the mesangial immunoglobulin G aggregate uptake in a model of specific mesangial cell injury. Isolated specific mesangial cell injury was developed in Lewis rats by...

journal_title：Nephron

authors： Singhal PC,Pan CQ,Sagar S,Valderrama E,Stahl RA

更新日期：1996-01-01 00:00:00

abstract：:We report a case of visceral leishmaniasis in a 38-year-old renal transplant recipient living in an endemic country. Antimonial derivatives induced a rapid remission. A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases. We suggest that the specific immunosuppressi...

journal_title：Nephron

authors： Moulin B,Ollier J,Bouchouareb D,Purgus R,Olmer M

更新日期：1992-01-01 00:00:00

abstract：:Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign. We diagnosed Wilson's disease in a 17-year-old male patient 6 years after his first episode of gross hematuria and 2 years after detection of hypercalciuria and nephrocalcinos...

journal_title：Nephron

authors： Hoppe B,Neuhaus T,Superti-Furga A,Forster I,Leumann E

更新日期：1993-01-01 00:00:00

abstract：:Renal scarring is considered to be a characteristic of reflux nephropathy. The effects of ulinastatin, a strong inhibitor of polymorphonuclear leukocyte elastase, on renal scarring following direct parenchymal or intravesical ascending infection by Serratia marcescens or Escherichia coli were determined. Four days of ...

journal_title：Nephron

authors： Matsumoto T,Haraoka M,Mizunoe Y,Takahashi K,Kubo S,Sakumoto M,Tanaka M,Kumazawa J

更新日期：1995-01-01 00:00:00

abstract：:The assessment of the hypothalamic-pituitary-adrenal axis in patients with chronic renal failure (CRF) on hemodialysis is often hampered by abnormal responses to the standard 1-mg dexamethasone suppression test. Various mechanisms have been proposed to explain this lack of suppressibility. The present study was design...

journal_title：Nephron

authors： Van Herle AJ,Birnbaum JA,Slomowitz LA,Mayes D,Chandler DW,Rosenblit PD,Nissenson A

更新日期：1998-09-01 00:00:00

abstract：:Because of the great problem of viral hepatitis in hemodialysis patients, the Italian Society of Nephrology decided to perform a national epidemiologic survey. We contacted 467 nephrological centers by a questionnaire which let us have information on 25,746 uremic patients: 18,338 on HD, 2,250 on PD and 5,176 with kid...

journal_title：Nephron

authors： Mioli VA,Balestra E,Bibiano L,Carletti P,Della Bella S,Fanciulli E,Gaffi G,Marinelli R,Perilli R,Ricciatti AM

更新日期：1992-01-01 00:00:00

abstract：:A 64-year-old woman presenting with a history of increasing oedema was found to have nephrotic syndrome with a 24-hour urinary protein excretion of 20.7 g and renal impairment with an initial serum creatinine level of 197 mumol/l (2.16 mg/dl). A renal tumour was demonstrated by ultrasound scanning and subsequent nephr...

journal_title：Nephron

authors： Woodrow G,Innes A,Ansell ID,Burden RP

更新日期：1995-01-01 00:00:00

abstract：:We describe a case of nephrotic syndrome (idiopathic membranous glomerulonephropathy) with high serum HDL cholesterol (91 mg/100 ml) which increased to 240 mg/100 ml following steroid therapy. The increase in HDL was mainly a result of increased HDL2 and increased plasma apolipoprotein A-I. ...

journal_title：Nephron

authors： Sasaki J,Hara F,Motooka T,Naito S,Arakawa K

更新日期：1985-01-01 00:00:00

abstract：:Previous work has shown that cigarette-smoking affects platelets and endothelium in men and women without renal failure. The present study compared 10 male habitual smokers receiving maintenance hemodialysis for chronic renal failure with 11 healthy male habitual smokers before and after controlled cigarette-smoking a...

journal_title：Nephron

authors： Davis JW,Arnold J,Wiegmann T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Scientists use preclinical models of acute kidney injury (AKI) to decipher mechanisms and develop therapy, but translation of therapies to patients remains poor. Models that better resemble patients, including those within clinical care, should be considered. SUMMARY:Mice provide many advantages to the stud...

journal_title：Nephron

authors： Billings FT 4th

更新日期：2019-01-01 00:00:00

abstract：:It has been assumed, but not documented, that hypercalcemia induces an appreciable reduction in the serum anion gap (AG) because it represents an increase in the level of unmeasured cations. To test this question, we retrospectively compared the data of 59 hypercalcemic patients with malignancy [group 1, serum Ca 13.3...

journal_title：Nephron

authors： Oster JR,Gutierrez R,Schlessinger FB,Taylor A,Federman DG,Vaamonde CA

更新日期：1990-01-01 00:00:00