Abstract:
:Diffuse crescentic glomerulonephritis was observed in a 40-year-old male patient who had a ventriculoatrial shunt implanted after a traffic accident 10 years previously. Immediately after treatment with immunosuppressants and plasma pheresis, signs of meningitis and septicemia developed. The responsible organism isolated was Staphylococcus albus. After the shunt was removed, clinical signs and renal function improved, associated with normalization of hypocomplementemia and disappearance of cryoglobulin and circulating immune complexes. Repeat renal biopsy performed 5 months after the removal of the shunt revealed mild mesangial proliferative and sclerotic glomerulonephritis with fibrous crescents. No apparent deposits observed in the initial biopsy were found on ultrastructural and immunofluorescent examinations. The reported cases with serial renal biopsies before and after the removal of the shunt were reviewed.
journal_name
Nephronjournal_title
Nephronauthors
Wakabayashi Y,Kobayashi Y,Shigematsu Hdoi
10.1159/000183441subject
Has Abstractpub_date
1985-01-01 00:00:00pages
111-7issue
1eissn
1660-8151issn
2235-3186journal_volume
40pub_type
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