Red blood cell osmotic fragility in chronically hemodialyzed patients.

abstract：:Serum specimens from 99 selected renal patients were examined over a 3-year period by both a hemagglutination technique (HA) and an indirect immunofluorescent (IIF) method for the presence of circulating antibody against tubular basement membrane (TBM). 11 patients were found with anti-TBM antibodies. 6 of them also h...

journal_title：Nephron

authors： Cattran DC

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION/AIMS:The Acute Kidney Injury Network classification is based on small increases in serum creatinine (sCr) for stage 1. This study investigated whether changes in the urinary concentration of neutrophil gelatinase-associated lipocalin (uNGAL) could predict small increases in sCr in patients undergoing coron...

journal_title：Nephron

authors： Souza DF,Reis SS,Botelho RV,Ferreira-Filho SR

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To develop and internally validate a multivariable prediction model based on simple clinical record data and laboratory tests and to estimate the probability of left-ventricular diastolic dysfunction (LVDD) in stable maintenance hemodialysis (MHD) patients without clinical heart failure. DESIGN:Cross-section...

journal_title：Nephron

authors： Sun L,Ji Y,Wang Y,Zhu D,Chen F,Zhang N,Shen E,Wang X

更新日期：2019-01-01 00:00:00

abstract：:Previous reports on the nephritogenic and immunological enhancing capacity of posttransplant circulating immune complexes (CICs) are conflicting and have been confined to the study of acute rejection episode (AR). This study was undertaken to assess the nephritogenicity of CICs in patients undergoing accelerated acute...

journal_title：Nephron

authors： Jordan SC,Sakai R,Ettenger RB,Fine RN

更新日期：1982-01-01 00:00:00

abstract：:Diabetic nephropathy (DN), a distinct manifestation of diabetic kidney disease, affects approximately 30% of patients with diabetes. While most attention has been focused on glomerular changes related to DN, there is growing evidence that tubulopathy is a key feature in the pathogenesis of this disease. The renal prox...

journal_title：Nephron

authors： Hinden L,Tam J

更新日期：2019-01-01 00:00:00

abstract：:A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...

journal_title：Nephron

authors： Takeuchi A,Yoshizawa N,Oshima S,Kubota T,Oshikawa Y,Akashi Y,Oda T,Niwa H,Imazeki N,Seno A

更新日期：1992-01-01 00:00:00

abstract：:Ischemic renal failure was produced in rabbits by occluding the renal arteries for 90 min. Group 1 (n = 8) received radiocontrast media at the time of occlusion, group 2 (n = 8) 24 h after occlusion, and group 3 (n = 8) 3 days after occlusion. Group 4 (n = 12) was subjected to ischemic injury alone, group 5 (n = 4) se...

journal_title：Nephron

authors： Schultz SG,Lavelle KJ,Swain R

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Scientists use preclinical models of acute kidney injury (AKI) to decipher mechanisms and develop therapy, but translation of therapies to patients remains poor. Models that better resemble patients, including those within clinical care, should be considered. SUMMARY:Mice provide many advantages to the stud...

journal_title：Nephron

authors： Billings FT 4th

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine dipstick albumin and CAC. The aim of this study is to investigate th...

journal_title：Nephron

authors： Song JJ,Lee KB,Hyun YY,Kim H

更新日期：2018-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:Renal biopsy specimens from 8 patients with IgA nephropathy (Berger's disease) were examined immunocytochemically at the light and electron microscopic levels with peroxidase-labeled antibodies to IgA, IgM, J chain and secretory component. In 2 of the 8 specimens heavy deposits of IgA, but no IgM, were found in the me...

journal_title：Nephron

authors： Komatsu N,Nagura H,Watanabe K,Nomoto Y,Kobayashi K

更新日期：1983-01-01 00:00:00

abstract：:Radial arterial spasm in uremic patients undergoing construction of internal arteriovenous (AV) dialysis fistulas was investigated transcutaneously using ultrasonic Doppler flowmetry. In 5 of 15 patients, radial arterial blood flow was significantly decreased 5 min after anastomosing the radial cephalic vein with the ...

journal_title：Nephron

authors： Owada A,Saito H,Mochizuki T,Tanaka M,Otsuka M,Yokoyama Y,Fukuda S

更新日期：1993-01-01 00:00:00

abstract：:In earlier studies, we have shown that induction of passive Heymann nephritis (PHN) by intrarenal infusion of anti-Fx1A antibodies provokes an immediate fall in renal blood flow (RBF) and glomerular filtration rate (GFR). This was probably mediated via the complement system, as infusion of the F(ab')2 fraction of anti...

journal_title：Nephron

authors： Sekse I,Iversen BM,Daha MR,Ofstad J

更新日期：1992-01-01 00:00:00

abstract：:During hemodialysis therapy, a large amount of water is removed from the patient's blood in a short time; however, blood pressure remains stable in most patients. As water is removed, the circulating serum proteins become more concentrated, resulting in a marked increase in the driving force which pulls water from the...

journal_title：Nephron

authors： Tabei K,Nagashima H,Imura O,Sakurai T,Asano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Sepsis and septic shock are life-threatening causes of acute kidney injury (AKI) frequently seen and managed in intensive care units (ICUs). Sepsis-associated AKI (SA-AKI) independently contributes to the mortality of sepsis. Understanding the potential factors involved in kidney function recovery may furthe...

journal_title：Nephron

authors： Chen JCY,Hu B,Frank RD,Kashani KB

更新日期：2020-01-01 00:00:00

abstract：:The serum levels of 25-hydroxycholecalciferol, 24,25-dihydroxycholecalciferol, and 1,25-dihydroxycholecalciferol were measured simultaneously in three groups of adults with different renal function: normal (n = 24), glomerular filtration rate (GFR) greater than 70 ml/min; moderately decreased (n = 15), GFR 5-35 ml/min...

journal_title：Nephron

authors： Rickers H,Christiansen C,Christensen P,Christensen M,Rødbro P

更新日期：1985-01-01 00:00:00

abstract：:The assessment of the hypothalamic-pituitary-adrenal axis in patients with chronic renal failure (CRF) on hemodialysis is often hampered by abnormal responses to the standard 1-mg dexamethasone suppression test. Various mechanisms have been proposed to explain this lack of suppressibility. The present study was design...

journal_title：Nephron

authors： Van Herle AJ,Birnbaum JA,Slomowitz LA,Mayes D,Chandler DW,Rosenblit PD,Nissenson A

更新日期：1998-09-01 00:00:00

abstract：:A long-term hemodialysis male patient was known to have systemic iron overload due to regular blood transfusions. As he was suspected to have aluminum overload, he received a single intravenous administration of desferrioxamine (that supported the hypothesis). Four days later, he became highly febrile with no focus of...

journal_title：Nephron

authors： Hoen B,Renoult E,Jonon B,Kessler M

更新日期：1988-01-01 00:00:00

abstract：:The effects of each of several tannins purified from Rhei Rhizoma on serum constituents were investigated in rats with adenine-induced renal failure. Blood levels of urea nitrogen, methylguanidine (MG), and guanidinosuccinic acid (GSA) were significantly decreased in rats given (-)-epicatechin 3-O-gallate at a dose of...

journal_title：Nephron

authors： Yokozawa T,Fujioka K,Oura H,Nonaka G,Nishioka I

更新日期：1991-01-01 00:00:00

abstract：:Cardiovascular disease is the major complication and cause of mortality in the dialysis population, accounting for about 40% of deaths. Oxidative stress has been strongly implicated in the pathogenesis of these events. As patients in end-stage renal disease (ESRD) are in a state of elevated free radical activity, the ...

journal_title：Nephron

authors： Wang NP,Lim PS,Chen TT,Thien LM,Wang TH,Hsu WM

更新日期：2002-12-01 00:00:00

abstract：:Previously, we have shown that insulin binding (IB) to erythrocytes was decreased in uremic patients and that hemodialysis corrected the receptor defect. In the present study cross-incubation experiments were performed using uremic and control erythrocytes and plasma. Incubation of control erythrocytes with uremic pla...

journal_title：Nephron

authors： Milutinović S,Breyer D,Janković N,Molnar V,Stefović A,Rocić B

更新日期：1983-01-01 00:00:00

abstract：:Computerized tomography (CT) has the advantage of allowing the isolation of trabecular bone of the axial skeleton, which is the more sensitive to metabolic changes. By means of single-energy X-ray CT we have devised a method for assessing trabecular bone mass (TBM) at L-4 vertebral body, which has an acceptable reprod...

journal_title：Nephron

authors： Torres A,Lorenzo V,Gonzalez-Posada JM

更新日期：1986-01-01 00:00:00

abstract：:In 2014 57.5% of HD patients and 62.7% of PD patients achieved the audit measure for phosphate. 29.0% of HD and 30.3% of PD patients had a serum phosphate above the audit standard range. 79.1% of HD and 79.7% of PD patients had adjusted calcium between 2.2–2.5 mmol/L. 57.4% of HD and 65.0% of PD patients had a serum P...

journal_title：Nephron

authors： Nicholas J,Evans R,Shaw C,Dawnay A

更新日期：2016-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) is a histological pattern of podocyte and glomerulus injury. FSGS can be primary and secondary to other diseases or due to a genetic cause. Strikingly, genetic causes for adult-onset FSGS are often overlooked, likely because identifying patients with genetic forms of FSGS base...

journal_title：Nephron

authors： Snoek R,Nguyen TQ,van der Zwaag B,van Zuilen AD,Kruis HME,van Gils-Verrij LA,Goldschmeding R,Knoers NVAM,Rookmaaker MB,van Eerde AM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:At present, the determination of dry weight in patients on hemodialysis is largely made empirically by trial and error. Extracellular volume (ECV) assessment by bioimpedance analysis (BIA) is a preferable technique for determining dry weight, and it also provides useful data on body composition. METHODS:We ...

journal_title：Nephron

authors： Chen YC,Chen HH,Yeh JC,Chen SY

更新日期：2002-09-01 00:00:00

abstract：:A previously described method for recovering a proximal renal tubular epitheal antigen (HRTE-1) from normal human kidney was modified by using ion-exchange and immunoaffinity chromatography in order to create easily reproducible conditions for antigen isolation. Radioiodinated HRTE-1 was then used to establish a 3-hou...

journal_title：Nephron

authors： Zager RA,Rubin NT,Ebert T,Maslov N

更新日期：1980-01-01 00:00:00

abstract：:Pruritus is a common symptom among patients undergoing long-term hemodialysis. However, its etiology remains unclear. In an attempt to clarify its cause we tried to correlate pruritus and its intensity with several serological variables in 94 hemodialysis patients. Our results show that higher serum aluminum concentra...

journal_title：Nephron

authors： Friga V,Linos A,Linos DA

更新日期：1997-01-01 00:00:00

abstract：:The daily urinary excretion of oxalate has been found to be lower than normal in patients with renal failure and the decrease to be directly proportional to the impairment of renal function. It has also been found that the gut flora from uremic patients destroys oxalate 'in vitro' more efficiently than the gut flora f...

journal_title：Nephron

authors： Camici M,Balestri PL,Lupetti S,Colizzi V,Falcone G

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of treatment for renal anemia in patients with chronic kidney disease (CKD). This meta-analysis was designed to evaluate their efficacy and safety. METHOD:Eight databases were searched for randomized controlled trials (RCTs). ...

journal_title：Nephron

authors： Wen T,Zhang X,Wang Z,Zhou R

更新日期：2020-01-01 00:00:00