Is aluminum toxicity responsible for uremic pruritus in chronic hemodialysis patients?

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：:The authors describe an unusual case of radial artery pseudoaneurysm in a patient with a Brescia-Cimino fistula. Evaluation of a pulsatile mass on the patient's forearm which occurred after hemodialysis led to a nondiagnostic fistulogram. Color flow ultrasound was helpful in identifying the nature of the abnormality, ...

journal_title：Nephron

authors： Labus TP,Trerotola SO,Savader SJ

更新日期：1996-01-01 00:00:00

abstract：:In order to estimate a regenerative response in the early phase after renal ischemia-reperfusion in rat, we examined the time course of the activation of epidermal growth factor receptor (EGFR) as a response of signal transduction pathway after 45 min ischemia in kidney. The activation of EGFR was observed 5-30 min af...

journal_title：Nephron

authors： Yano T,Yazima S,Hagiwara K,Ozasa H,Ishizuka S,Horikawa S

更新日期：1999-02-01 00:00:00

abstract：:Chronic cyclosporine nephrotoxicity is characterized morphologically by cortical interstitial fibrosis. The most important collagens involved in renal fibrosis are collagen types I and III. In order to estimate the synthesis of type III and type I collagens, we analyzed serum levels of the amino-terminal propeptide of...

journal_title：Nephron

authors： Heickendorff L,Frost L,Madsen JK,Pedersen EB

更新日期：1994-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:The effect of water immersion to the neck on renal calcium and magnesium handling was studied in 11 nephrotic patients. There was an increase in the urinary excretion of both calcium and magnesium on immersion, and a return towards preimmersion control values in the hour following immersion. Clearances of calcium and ...

journal_title：Nephron

authors： Brown C,Sutton JV,Adler A,Feinroth MV,Feinroth M,Friedman EA,Berlyne GM

更新日期：1983-01-01 00:00:00

abstract：:Mitochondria contain electron-dense particles, partly composed of an amorphous form of calcium phosphate. We have used electron microscopy from percutaneous renal biopsy material to analyze mitochondrial granulation in the proximal renal tubule of nonuremic and uremic children. Based on a technique of cutting mitochon...

journal_title：Nephron

authors： Whitney JO,Goodman JR,Piel CF

更新日期：1979-01-01 00:00:00

abstract：:Serum concentrations of soluble interleukin 2 receptor (IL-2R) were measured in 65 hemodialysis patients and compared with serum levels of beta 2-microglobulin and tissue polypeptide antigen (TPA). Elevated IL-2R levels, found in 85% of examined patients, correlated with elevated TPA serum concentrations (p less than ...

journal_title：Nephron

authors： Walz G,Kunzendorf U,Josimovic-Alasevic O,Preuschoff L,Schwarz A,Keller F,Asmus G,Offermann G,Diamantstein T,Distler A

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Bleeding is the most frequent complication of kidney biopsy. Although bleeding risk in patients with AA amyloidosis after kidney biopsy has not been studied in a large population, AA amyloidosis has long been perceived as a risk factor for bleeding. The aim of the present study was to evaluate post-biopsy bl...

journal_title：Nephron

authors： Altindal M,Yildirim T,Turkmen E,Unal M,Boga I,Yilmaz R,Arici M,Altun B,Erdem Y

更新日期：2015-01-01 00:00:00

abstract：:This study was undertaken to test the hypothesis that ischemia prior to transplantation causes tubular damage without clinical evidence of graft dysfunction. The urinary excretion of fructose-1,6-bisphosphatase (EC 3.1.3.11, FBPase), a cytosolic enzyme located exclusively in the proximal tubules, and the lysosomal enz...

journal_title：Nephron

authors： Kotanko P,Margreiter R,Pfaller W

更新日期：1997-01-01 00:00:00

abstract：:We encountered 11 patients with aluminum-associated bone disease (AABD), and treated them with deferoxamine (DFO). In 3 patients, a second bone biopsy was done during DFO treatment. Clinical features of AABD were compared with surgically proven secondary hyperparathyroidism (2 degrees HPT) with osteitis fibrosa on X-r...

journal_title：Nephron

authors： Iwamoto N,Ono T,Yamazaki S,Fukuda T,Kondo M,Yamamoto N,Hiratake Y,Masugi Y,Kubo Y,Hino M

更新日期：1986-01-01 00:00:00

abstract：:A modified sieving technique has been developed to isolate pure glomeruli from monkey, sheep, dog, rabbit and rat kidney. Glomeruli from all these species have been grown in tissue culture and the glomerular cell outgrowth studied by light microscopy and time-lapse cinemicroscopy. The pattern of growth was the same fo...

journal_title：Nephron

authors： Holdsworth SR,Glasgow EF,Atkins RC,Thomson NM

更新日期：1978-01-01 00:00:00

abstract：:In order to evaluate effects of metabolic acidosis on glucose metabolism in uremia, we studied, by an intravenous glucose tolerance test (IVGTT), 46 patients with severe chronic renal failure divided into three groups according to their blood bicarbonate (BB) values: group A formed by 15 patients without or with light...

journal_title：Nephron

authors： Allegra V,Mengozzi G,Martimbianco L,Vasile A

更新日期：1993-01-01 00:00:00

abstract：:We determined the clinical and immunopathological effects of dilazep hydrochloride (dilazep) on IgA nephropathy of ddY mice. Group I (early-treatment group, n = 10) was orally treated with 300 mg/kg body weight of this drug from 12 weeks of age until 60 weeks of age, and group II (late-treatment group, n = 10) was als...

journal_title：Nephron

authors： Hayashi T,Kaneko S,Thang NT,Shou I,Shirato I,Tomino Y

更新日期：2000-11-01 00:00:00

abstract：:5 patients, including 4 with partial lipodystrophy and 1 with dense deposit disease (type II mesangiocapillary glomerulonephritis; MCGN), had positive C3 nephritic factor assays by both a crossed-gel immunoelectrophoretic and a magnesium-dependent hemolytic assay. One or more early classic complement component was sig...

journal_title：Nephron

authors： McLean RH,Siegel NJ,Kashgarian M

更新日期：1980-01-01 00:00:00

abstract：:Chyloperitoneum is a rare condition in patients undergoing peritoneal dialysis. We report here a patient who developed chylous ascites during the course of tuberculous peritonitis. The diagnosis was confirmed by cultures of dialysate and peritoneal biopsy, and laparoscopy revealed severe hyperemia and intestine adhesi...

journal_title：Nephron

authors： Huang CH,Chen HS,Chen YM,Tsai TJ

更新日期：1996-01-01 00:00:00

abstract：:The recent experience of six large trials of antihypertensive therapy has not clearly demonstrated any beneficial effect on the prevention of coronary heart disease (CHD). The data from the HDFP study have been analyzed by three cholesterol strata at baseline. The higher the baseline cholesterol levels, the greater th...

journal_title：Nephron

authors： Schneider KA,Heyden S,Ford C

更新日期：1987-01-01 00:00:00

abstract：:The urinary transforming growth factor beta (TGF-beta) excretion was measured in 33 patients including 10 with systemic lupus erythematosus (SLE), 8 with focal glomerular sclerosis (FGS), 9 with IgA nephropathy (IgAN), and 6 with membranous nephropathy (MN), and in 7 healthy subjects by enzyme-linked immunosorbent ass...

journal_title：Nephron

authors： Kanai H,Mitsuhashi H,Ono K,Yano S,Naruse T

更新日期：1994-01-01 00:00:00

abstract：:It is unknown whether continuous renal replacement techniques result in diminished morbidity and mortality when compared to conventional dialytic techniques. To investigate this issue a previously described, retrospectively studied group of critically ill patients with severe acute renal failure treated by conventiona...

journal_title：Nephron

authors： Bellomo R,Farmer M,Parkin G,Wright C,Boyce N

更新日期：1995-01-01 00:00:00

abstract：:After successful renal transplantation there is continuing malabsorption of calcium and phosphorus. This is due in part to impaired glomerular filtration rate, and in part to the action of steroid on calcium and phosphorus absorption. The effect of steroids is most marked over the first 18 months after transplantation...

journal_title：Nephron

authors： Walker GS,Peacock M,Marshall DH,Giles GR,Davison AM

更新日期：1980-01-01 00:00:00

abstract：:A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...

journal_title：Nephron

authors： Kelley WN

更新日期：1975-01-01 00:00:00

abstract：:To explain the occurrence of tubular and glomerular proteinuria in patients with primarily tubular or glomerular dysfunction, it is usually assumed that the mechanisms responsible for the renal tubular transport of small and large proteins are different. The present in vivo study does not support this hypothesis since...

journal_title：Nephron

authors： Bernard A,Viau C,Ouled A,Lauwerys R

更新日期：1987-01-01 00:00:00

abstract：:The TINU syndrome (tubulointerstitial nephritis and uveitis) was first described by Dobrin et al. in 1975. Since then, more than 50 cases have been documented each with diverse immunopathogenetic and genetic characteristics. The aim of this report is to describe a case of TINU associated with reduced complement levels...

journal_title：Nephron

authors： Conz PA,Milan M,Bragantini L,La Greca G,Bevilacqua PA

更新日期：2001-11-01 00:00:00

abstract：:Permanent loss of the ultrafiltration (UF) capacity of the peritoneum has been observed with an increasing frequency among our patients treated by long-term intermittent (IPD) and/or continuous ambulatory peritoneal dialysis (CAPD). The analysis of various characteristics of our PD population (patients age, dialysis t...

journal_title：Nephron

authors： Slingeneyer A,Canaud B,Mion C

更新日期：1983-01-01 00:00:00

abstract：:The serum levels of 25-hydroxycholecalciferol, 24,25-dihydroxycholecalciferol, and 1,25-dihydroxycholecalciferol were measured simultaneously in three groups of adults with different renal function: normal (n = 24), glomerular filtration rate (GFR) greater than 70 ml/min; moderately decreased (n = 15), GFR 5-35 ml/min...

journal_title：Nephron

authors： Rickers H,Christiansen C,Christensen P,Christensen M,Rødbro P

更新日期：1985-01-01 00:00:00

abstract：:Tubular necrosis elicits a process of renal tissue repair characterized by an increase of cell turnover in tubular epithelium. The present study was undertaken to examine the distribution of epidermal growth factor (EGF) and/or of its larger precursor proEGF in the kidney undergoing tubular regeneration. Sprague-Dawle...

journal_title：Nephron

authors： Nonclercq D,Toubeau G,Lambricht P,Heuson-Stiennon JA,Laurent G

更新日期：1991-01-01 00:00:00

abstract：:By April 26, 2020, infections related to coronavirus disease 2019 (COVID-19) affected people from 210 countries and caused 203,818 reported deaths worldwide. A few studies discussed the outcome of COVID-19 in kidney transplant recipients. This short series demonstrates our experience in managing COVID-19 disease in re...

journal_title：Nephron

authors： Elhadedy MA,Marie Y,Halawa A

更新日期：2020-12-08 00:00:00

abstract：:In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...

journal_title：Nephron

authors： Lenz T,Thiede HM,Nussberger J,Atlas SA,Distler A,Schulte KL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:Diastolic dysfunction (DD) and low levels of thyroid hormones (TH) are frequent found in chronic kidney disease; both are associated with all-cause and cardiovascular mortality. However, a link between them has not yet been established. The aim of this study was to analyze DD as a surrogate marker of fi...

journal_title：Nephron

authors： Sánchez V,Paniagua R,Prado MD,Mora C,Orihuela O,Martínez-Baca F,Pérez EE,Calzada C,Romero R,Avila M

更新日期：2017-01-01 00:00:00