Redistribution of epidermal growth factor immunoreactivity in renal tissue after nephrotoxin-induced tubular injury.

abstract：:A gradual loss of cell viability was observed during in vitro incubation of peritoneal cells from chronically uremic mice in commercial peritoneal dialysis solutions. The magnitude of this cytotoxicity toward peritoneal cells harvested from uremic mice and controls was comparable. Resident peritoneal cells were always...

journal_title：Nephron

authors： Gallimore B,Gagnon RF,Stevenson MM

更新日期：1986-01-01 00:00:00

abstract：:The purpose of the study was to investigate the effects of parathyroid hormone (PTH) infusion on antioxidant enzyme activity and lipid peroxidation of erythrocytes in five-sixths nephrectomized (Nx) rats. Five-sixths Nx rats had a higher osmotic fragility in red blood cells (RBC). Thyroparathyroidectomy (TPTX) effecti...

journal_title：Nephron

authors： Chen SM,Young TK

更新日期：1996-01-01 00:00:00

abstract：:Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

journal_title：Nephron

authors： Kirschbaum BB

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The prevalence of subclinical atherosclerosis and the main predictors of progression of this condition in patients undergoing peritoneal dialysis (PD) have been insufficiently investigated. OBJECTIVES AND METHOD:Following a prospective, multicenter, observational design, we studied 237 patients who were tre...

journal_title：Nephron

authors： Pérez Fontán M,Borràs Sans M,Bajo Rubio MA,Rodriguez-Carmona A,Betriu A,Valdivielso JM,Fernández E,NEFRONA Study investigators.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:The renal prognosis of post-renal acute kidney injury (PoR-AKI) has not been verified so far. The objective of this study was to assess the association of baseline anemia with long-term renal prognosis in patients with PoR-AKI. METHODS:We performed a multicenter retrospective cohort study. Consecutive ...

journal_title：Nephron

authors： Sasaki S,Kawarazaki H,Hasegawa T,Shima H,Naganuma T,Shibagaki Y

更新日期：2017-01-01 00:00:00

abstract：:Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but ...

journal_title：Nephron

authors： Carrara C,Abbate M,Sabadini E,Remuzzi G

更新日期：2017-01-01 00:00:00

abstract：:The size distribution pattern of circulating rPRL was studied in intact control (C) rats and in three uremic models, namely urine autoinfusion (UA), bilateral ureteral ligation (BUL), and bilateral nephrectomy (BNx). Plasmas were chromatographed by gel filtration in Sephadex G-100. Rat PRL was measured by RIA. The rPR...

journal_title：Nephron

authors： Martin-Oar JE,Cachofeiro MV,Rodriguez-Puyol D,Hernando L,López-Novoa JM

更新日期：1984-01-01 00:00:00

abstract：:Hypokalemia and potassium depletion are frequent complications of amphotericin B therapy. Both ischemic and gentamicin-induced renal failure is potentiated by potassium depletion; it is, therefore, possible that amphotericin B nephrotoxicity is similarly influenced. This study evaluated whether the acute nephrotoxic r...

journal_title：Nephron

authors： Bernardo JF,Murakami S,Branch RA,Sabra R

更新日期：1995-01-01 00:00:00

abstract：:X-linked nephrogenic diabetes insipidus (NDI) is a rare disease caused by mutations in the vasopressin V2 receptor (AVPR2) gene. We analyzed the AVPR2 gene in 6 unrelated Korean families with X-linked NDI, and found 6 novel mutations. Two of them were missense point mutations, 2 were short deletions causing frameshift...

journal_title：Nephron

authors： Cheong HI,Park HW,Ha IS,Moon HN,Choi Y,Ko KW,Jun JK

更新日期：1997-01-01 00:00:00

abstract：:Here, we review the most recent findings on the effects of SARS-CoV-2 infection on kidney diseases, including acute kidney injury, and examine the potential effects of ARBs on the outcomes of patients with COVID-19. Lastly, we discuss the clinical management of COVID-19 patients with existing chronic renal disorders, ...

journal_title：Nephron

authors： Perico L,Benigni A,Remuzzi G

更新日期：2020-01-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) to undergo spontaneous and induced interleukin-1 (IL-1) production was examined in 10 healthy controls and in 10 patients undergoing intermittent hemodialysis (HD) using cuprophane membranes. Extracellular and cytoplasmic IL-1 activity was assayed by biologic a...

journal_title：Nephron

authors： Blumenstein M,Schmidt B,Ward RA,Ziegler-Heitbrock HW,Gurland HJ

更新日期：1988-01-01 00:00:00

abstract：:Hypouricemia seen with hyponatremia related to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) results from an increase in uric acid renal clearance. We studied the mechanism of the increase of uric acid excretion in 6 SIADH patients through pyrazinamide (PZA), which decreases tubular secretion...

journal_title：Nephron

authors： Decaux G,Dumont I,Waterlot Y,Hanson B

更新日期：1985-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:Cytomegalovirus is the most important viral infection in kidney transplants, but rarely affects the allograft after the sixth month posttransplantation. We present a patient who developed renal failure eighteen months posttransplant; a kidney biopsy showed cytomegalovirus inclusions, acute tubular necrosis and mild in...

journal_title：Nephron

authors： Trimarchi H,Jordan R,Iotti A,Forrester M,Iotti R,Freixas E,Martínez J,Schropp J,Pereyra H,Efrón E

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND/AIM:The ultrasonic transit time is currently the best method for measuring the blood flow rate in the extracorporeal hemodialysis circuit. The purpose of this study was to analyze the differences between blood flow as indicated by the hemodialysis blood roller pump (prescribed blood flow) and by an ultrasoni...

journal_title：Nephron

authors： Teruel JL,Fernández Lucas M,Marcén R,Rodríguez JR,López Sánchez J,Rivera M,Liaño F,Ortuño J

更新日期：2000-06-01 00:00:00

abstract：:An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, theref...

journal_title：Nephron

authors： Ehrenfeld M,Licht A,Stessman J,Yanko L,Rosenmann E

更新日期：1977-01-01 00:00:00

abstract：:Serum and urinary concentrations of NCl, the non collagenous globular domain of collagen IV, were used as markers for turnover of basement membranes. NCl levels were studied in membranous glomerulonephritis and diabetic nephropathy. Thirteen patients with membranous glomerulonephritis and 8 insulin-dependent diabetic ...

journal_title：Nephron

authors： Torffvit O,Agardh CD,Alm P,Wieslander J

更新日期：1991-01-01 00:00:00

abstract：:This prospective study was designed to evaluate the eventual correction of anemia and iron status in 39 iron-deficient uremics starting hemodialysis. Nine patients (control group) had no iron supplementation, 10 had oral ferrous iron, and 20 were treated with intravenous iron gluconate. Follow-up periods were 12 month...

journal_title：Nephron

authors： Fudin R,Jaichenko J,Shostak A,Bennett M,Gotloib L

更新日期：1998-01-01 00:00:00

abstract：:From a review of the literature regarding kinetic models used for assessing the adequacy of hemodialysis, no definite conclusions can be drawn as to whether the classical urea kinetic model (UKM) or modified direct dialysis quantification (mDDQ) is more reliable. We compared mDDQ with classical UKM and with a modified...

journal_title：Nephron

authors： Bosticardo GM,Alloatti S

更新日期：1996-01-01 00:00:00

abstract：:To investigate autonomic mechanisms underlying persistent hypotension in long-term hemodialysis patients, high-frequency (HF, > 0.15 Hz) and low-frequency (LF, 0.04-0.15 Hz) components of heart rate variability and plasma noradrenaline were analyzed in 10 persistently hypotensive hemodialysis patients (group H), 11 no...

journal_title：Nephron

authors： Takahashi H,Matsuo S,Toriyama T,Kawahara H,Hayano J

更新日期：1996-01-01 00:00:00

abstract：:Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...

journal_title：Nephron

authors： Hsu CH,Kurtz TW

更新日期：1981-01-01 00:00:00

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：:A 5-year-old Chinese girl had had absence seizures and received sodium valproate (VPA) treatment which provided good control. Six months later, she developed interstitial nephritis with proteinuria and microhematuria. Renal biopsy revealed interstitial nephritis with granular deposition of immunoglobulin G (IgG) and C...

journal_title：Nephron

authors： Lin CY,Chiang H

更新日期：1988-01-01 00:00:00

abstract：:Lipoproteins might be involved in the pathogenesis of glomerular damage. Uptake of low-density lipoprotein (LDL) by cultured human glomerular cells has been studied using LDL, labelled with the fluorescent probe 1,1'-dioctadecyl-3,3,3'3'-tetramethyl-indocarbocyanine perchlorate (diI). Cells have been characterised usi...

journal_title：Nephron

authors： Rayner HC,Horsburgh T,Brown SL,Lavender FL,Winder AF,Walls J

更新日期：1990-01-01 00:00:00

abstract：:Methylguanidine (MG), guanidinosuccinic acid (GSA) and creatinine (Cr), which accumulate in the body in parallel with the progress of renal failure after adenine administration, were given separately to rats in order to compare their toxicities. Food containing adenine was given to rats for 24 days to induce renal fai...

journal_title：Nephron

authors： Yokozawa T,Mo ZL,Oura H

更新日期：1989-01-01 00:00:00

abstract：:Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination. ...

journal_title：Nephron

authors： Melappioni M,Baldassari M,Baldini S,Radicioni R,Panichi N

更新日期：1992-01-01 00:00:00

abstract：:The fall in white blood cells (WBC) and arterial oxygen pressure that occurs during hemodialysis was investigated as a function of different dialysis membranes and different sterilization methods. 8 chronic hemodialysis patients were studied and each was dialyzed with three different membranes: cellulosic hollow fiber...

journal_title：Nephron

authors： Hakim RM,Lowrie EG

更新日期：1982-01-01 00:00:00

abstract：:End-stage renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease (CKD). ESRD claims many lives every year. It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the future development of CKD and ESRD. While our understanding of the pathophysiolog...

journal_title：Nephron

authors： Ó hAinmhire E,Humphreys BD

更新日期：2017-01-01 00:00:00

abstract：:The porphyrin status of 38 renal transplant patients was investigated using a sensitive thin-layer chromatographic assay. Abnormalities of porphyrin synthesis observed in patients on hemodialysis were generally reversed on receipt of a transplant with sustained good renal function. Urinary coproporphyrin levels and th...

journal_title：Nephron

authors： Day RS,Eales L

更新日期：1982-01-01 00:00:00

abstract：:Obstructed shunt vessels were studied immunohistochemically to clarify the mechanism of shunt obstruction in hemodialysis patients. The subjects were 12 hemodialysis patients with shunt obstruction, and 8 patients newly started on hemodialysis were used as the controls. Cryosections of shunt tissue were prepared and s...

journal_title：Nephron

authors： Taniguchi Y,Yorioka N,Yamashita K,Masaki T,Yamakido M

更新日期：1999-01-01 00:00:00