Late-onset cytomegalovirus-associated interstitial nephritis in a kidney transplant.

abstract：:We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...

journal_title：Nephron

authors： Derbyshire ND,Asscher AW,Matthews PN

更新日期：1989-01-01 00:00:00

abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha) and its soluble TNF receptors 55 and 75 (sTNFR55, sTNFR75), interleukin-1 beta (IL-1BETA) and interleukin-6 (IL-6) were measured in plasma from 13 patients with the hemolytic uremic syndrome (HUS) on admission. No significant changes in the plasma levels of TNF-alp...

journal_title：Nephron

authors： van de Kar NC,Sauerwein RW,Demacker PN,Grau GE,van Hinsbergh VW,Monnens LA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：:Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination. ...

journal_title：Nephron

authors： Melappioni M,Baldassari M,Baldini S,Radicioni R,Panichi N

更新日期：1992-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:Inflammation is broadly recognized as an important factor in the pathogenesis of acute kidney injury (AKI), but pharmacological approaches to alleviate inflammation in AKI have been without success in clinical trials. Neuromodulation by nonpharmacological methods is emerging as a novel therapeutic strategy to treat in...

journal_title：Nephron

authors： Tanaka S,Inoue T,Hossack JA,Okusa MD

更新日期：2017-01-01 00:00:00

abstract：:The local cutaneous inflammatory response to DMCB sensitization was positive in only 35% of 20 uremic patients, and the delayed skin reaction was positive in only 15%. The reaction to DMCB challenge was markedly delayed in some patients. Improved response to DNCB re-challenge followed levamisole administration in only...

journal_title：Nephron

authors： Modai D,Sagi DB,Maor J

更新日期：1980-01-01 00:00:00

abstract：:Conglomerates of food and mucus or phytobezoars composed of vegetable matter are sometimes found in the stomach in the general population. Reports of phytobezoars in uremic patients are, however, scarce. Here we describe 2 uremic patients in which esophagogastroduodenoscopy was performed due to dyspepsia associated wi...

journal_title：Nephron

authors： Catalano C,Leone L,Fabbian F,Conz PA

更新日期：2002-03-01 00:00:00

abstract：:Calcitonin, whatever its origin, produces a decrease in the renal tubular reabsorption of sodium, phosphate and calcium in man and in the rat. Renal receptors for calcitonin have been demonstrated in the membranes of rat tubular cells using 125I salmon calcitonin as a tracer. Hormone-receptor interaction initiates the...

journal_title：Nephron

authors： Ardaillou R

更新日期：1975-01-01 00:00:00

abstract：:The decreases in serum osmolality as well as the rate of ultrafiltration during hemodialysis and the influence of each upon the side effects of this treatment were studied in 13 chronic stable dialysis patients. Mannitol (9 mosm/kg water) was infused in two out of four dialyses, in a double blind fashion. A solution o...

journal_title：Nephron

authors： Rosa AA,Shideman J,McHugh R,Duncan D,Kjellstrand CM

更新日期：1981-01-01 00:00:00

abstract：:The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...

journal_title：Nephron

authors： Kang XX,Hirano T,Oka K,Tamaki T,Sakurai E,Kaji N,Yoshida M,Kozaki M

更新日期：1991-01-01 00:00:00

abstract：:Mizoribine has been shown to possess an immunosuppressive action that inhibits the proliferation of lymphocytes selectively by interfering with inosine monophosphate dehydrogenase. Recent studies have demonstrated that mizoribine improves renal tubulointerstitial fibrosis in the rat model of unilateral ureteral obstru...

journal_title：Nephron

authors： Sato N,Shiraiwa K,Kai K,Watanabe A,Ogawa S,Kobayashi Y,Yamagishi-Imai H,Utsunomiya Y,Mitarai T

更新日期：2001-10-01 00:00:00

abstract：AIM:To clarify the role of leukocyte subsets in the development of glomerulosclerosis (GS) and interstitial lesions which may contribute to the prognosis of membranous nephropathy (MN), we investigated infiltrating cells in both glomeruli and interstitium in biopsy specimens. METHODS:Forty-one cases of MN were divided...

journal_title：Nephron

authors： Saito T,Yusa A,Soma J,Ootaka T,Sato H,Ito S

更新日期：1998-12-01 00:00:00

abstract：:Cadmium-induced renal effects were followed (1989) in 16 workers previously exposed to cadmium, who had been shown 5 years earlier to have had tubular damage; all but 1 worker had persistent tubular damage (beta 2-microglobulin > 60 micrograms/mmol creatinine). The mean glomerular filtration rate (GFR) decreased from ...

journal_title：Nephron

authors： Järup L,Persson B,Edling C,Elinder CG

更新日期：1993-01-01 00:00:00

abstract：:In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis ...

journal_title：Nephron

authors： Fuss M,De Backer M,Brauman J,Nijs-Dewolf N,Manderlier T,Brauman H,Corvilain J

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND/AIMS:Renal function deteriorates with age, but a few studies have addressed this longitudinally in elderly women. Our objective was, using 5 estimated glomerular filtration rates (eGFR)-equations, to evaluate changes in renal function and association with adverse outcomes for a decade in 75-year-old women. ...

journal_title：Nephron

authors： Malmgren L,McGuigan FE,Berglundh S,Westman K,Christensson A,Åkesson K

更新日期：2015-01-01 00:00:00

abstract：:Nonspecific symptoms are common in dialysis patients but few methods are available to measure their severity and their response to alteration in dialysis therapy. To determine the clinical features and measure the severity of the most important symptoms in end-stage renal disease (ESRD) patients, 97 dialysis patients ...

journal_title：Nephron

authors： Parfrey PS,Vavasour HM,Henry S,Bullock M,Gault MH

更新日期：1988-01-01 00:00:00

abstract：:Renal handling of urate, xanthine and hypoxanthine was studied in a hypouricemic patient who had increased plasma concentrations of xanthine and hypoxanthine. The patient, a 50-year-old man, had been suffering from Parkinson's disease, while neither systemic disorders nor particular renal diseases known to affect plas...

journal_title：Nephron

authors： Kawachi M,Kono N,Kiyokawa H,Mineo I,Nakajima H,Shimizu T,Yorifuji S,Kuwajima M,Tarui S

更新日期：1992-01-01 00:00:00

abstract：:To verify the action of heparin on peritoneal transport, we selected 20 patients on acute peritoneal dialysis and performed two 2-hour cycles with 2,000 cm3 of a 1.5% solution, adding 2,000 units of heparin to the second cycle. The patients were also randomized into 2 groups: group A, adding 1.5 mg gentamycin/kg to th...

journal_title：Nephron

authors： Ponce SP,Barata JD,Santos JR

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Complete remission (CR) and partial remission (PR) are beneficial to the long-term outcome of patients with idiopathic membranous nephropathy (iMN). However, we are lacking in studies that evaluate the clinical predictors of response to treatment with prednisone plus cyclophosphamide (CP). The objectives of ...

journal_title：Nephron

authors： Li S,Wang L,Zhang M,Zhou W,Fang W,Wang Q,Qi C,Mou S,Shao X,Ni Z

更新日期：2017-01-01 00:00:00

abstract：:The size distribution pattern of circulating rPRL was studied in intact control (C) rats and in three uremic models, namely urine autoinfusion (UA), bilateral ureteral ligation (BUL), and bilateral nephrectomy (BNx). Plasmas were chromatographed by gel filtration in Sephadex G-100. Rat PRL was measured by RIA. The rPR...

journal_title：Nephron

authors： Martin-Oar JE,Cachofeiro MV,Rodriguez-Puyol D,Hernando L,López-Novoa JM

更新日期：1984-01-01 00:00:00

abstract：:Increased free-radical production leading to oxidative stress may contribute to the development of cardiovascular complications in haemodialysis patients. The ferroxidase activity of caeruloplasmin forms an important component of antioxidant defences in body fluids. The aim of this study was to assess ferroxidase acti...

journal_title：Nephron

authors： Roxborough HE,Mercer C,McMaster D,Maxwell AP,Young IS

更新日期：2000-03-01 00:00:00

abstract：:The mechanisms by which intercurrent bacterial infections are associated with increased tissue injury in some forms of glomerulonephritis may include complement activation by bacteria and subsequent increased glomerular neutrophil (PMN) infiltration. We have studied the effect of complement activation after cobra veno...

journal_title：Nephron

authors： Savige JA,Dash AC,Rees AJ

更新日期：1989-01-01 00:00:00

abstract：:Dysfunction of the host defense against infection in hemodialysis (HD) patients has major clinical and socioeconomic implications. T helper type 1 (Th1) and type 2 (Th2) cytokines are implicated in regulating the immune responses and, therefore, may be involved in impaired status. The present study was designed to exa...

journal_title：Nephron

authors： Daichou Y,Kurashige S,Hashimoto S,Suzuki S

更新日期：1999-01-01 00:00:00

abstract：:Cardiovascular complications seriously affect posttransplant survival in patients after successful renal transplantation. Abnormalities in blood rheology may contribute to these complications. Therefore, we studied the blood rheology before and during a 1-year observation period after grafting in 9 patients by serial ...

journal_title：Nephron

authors： Koppensteiner R,Derfler K,Ehringer H

更新日期：1996-01-01 00:00:00

abstract：:We report a case of rapidly progressive glomerulonephritis due to antiglomerular basement membrane (anti-GBM) antibodies that progressed to end-stage renal disease in a 35-year-old man who used intranasal cocaine on an occasional basis. In contrast to many prior reports of acute renal failure occurring with cocaine-as...

journal_title：Nephron

authors： Peces R,Navascués RA,Baltar J,Seco M,Alvarez J

更新日期：1999-01-01 00:00:00

abstract：:Renin substrate concentrations and the release of renin in response to the rapid removal of 15 ml/kg weight blood or subcutaneous administration of 500 microgram/kg body weight isoproterenol were measured in control rats and animals recovering from prior myohemoglobinuric acute renal failure (recovery rats). Blood for...

journal_title：Nephron

authors： Carvalho JS,Landwehr DM,Oken DE

更新日期：1978-01-01 00:00:00

abstract：:The effects of contrast media on renal function and the cortical retention of contrast media after abdominal angiography were investigated. Sixteen nondiabetic patients with predialytic chronic renal failure received either the nonionic dimeric contrast medium iodixanol or the monomeric contrast medium iohexol in a do...

journal_title：Nephron

authors： Jakobsen JA,Berg KJ,Kjaersgaard P,Kolmannskog F,Nordal KP,Nossen JO,Rootwelt K

更新日期：1996-01-01 00:00:00

abstract：:It has been generally accepted that acidosis results in hyperkalemia because of shifts of potassium from the intracellular to the extracellular compartment. There is ample clinical and experimental evidence, however, to support the conclusion that uncomplicated organic acidemias do not produce hyperkalemia. In acidosi...

journal_title：Nephron

authors： Perez GO,Oster JR,Vaamonde CA

更新日期：1981-01-01 00:00:00

abstract：:As with many other amino acids the transport of cystine across the tubular epithelium is coupled to a parallel transport of sodium. We have studied the effect of a sodium-restricted diet on the urinary excretion of cystine in 13 patients with cystinuria, 7 of whom were treated with the SH compound tiopronin (2-mercapt...

journal_title：Nephron

authors： Lindell A,Denneberg T,Edholm E,Jeppsson JO

更新日期：1995-01-01 00:00:00