Clinical Predictors of Response to Prednisone Plus Cyclophosphamide in Patients with Idiopathic Membranous Nephropathy.

abstract：:Chronic kidney disease (CKD) is a worldwide public health problem associated with a high prevalence of cardiovascular disease (CVD) and impaired quality of life. Previous research for preventing loss of glomerular filtration rate (GFR) has focused on reducing blood pressure (BP) and proteinuria. Angiotensin converting...

journal_title：Nephron

authors： Ahmed A,Jorna T,Bhandari S

更新日期：2016-01-01 00:00:00

abstract：:Parathyroidectomy was carried out in 26 patients over a 14-year period. Excellent results were obtained in patients with severe hyperparathyroidism. Vascular calcification, hypercalcaemia and pruritus did not justify surgery unless associated with unequivocal hyperparathyroidism. 13 patients required intravenous calci...

journal_title：Nephron

authors： Dawborn JK,Brown DJ,Douglas MC,Eddey HH,Heale WF,Thomas DP,Xipell JM

更新日期：1983-01-01 00:00:00

abstract：:In this study, we examined the hypothesis whether exogenous administration of L-lysine in drinking water would reduce nonenzymatic glycation of glomerular basement membrane (GBM) collagen and thus albuminuria in streptozotocin-diabetic rats. The rationale is that the administered lysine would combine with the circulat...

journal_title：Nephron

authors： Jyothirmayi GN,Modak R,Reddi AS

更新日期：2001-02-01 00:00:00

abstract：:We studied the effects of oral furosemide, 80 mg/day for 7 days, on the response of urinary excretion of phosphate and cyclic AMP to exogenous parathyroid extract (PTE) in 6 normal subjects. All 6 subjects had marked increases in urinary calcium and a significant increase in urinary cyclic AMP from the control to the ...

journal_title：Nephron

authors： Fujita T,Delea CS,Bartter FC

更新日期：1985-01-01 00:00:00

abstract：:In the present study, activity of polymorphonuclear leukocyte (PMNL) intracellular antioxidant enzymes, i.e. catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX), was assessed in CRF patients on hemodialysis (HD), or continuous ambulatory peritoneal dialysis (CAPD) and in healthy controls. The activit...

journal_title：Nephron

authors： Shurtz-Swirski R,Mashiach E,Kristal B,Shkolnik T,Shasha SM

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Bleeding is the most frequent complication of kidney biopsy. Although bleeding risk in patients with AA amyloidosis after kidney biopsy has not been studied in a large population, AA amyloidosis has long been perceived as a risk factor for bleeding. The aim of the present study was to evaluate post-biopsy bl...

journal_title：Nephron

authors： Altindal M,Yildirim T,Turkmen E,Unal M,Boga I,Yilmaz R,Arici M,Altun B,Erdem Y

更新日期：2015-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：:Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign. We diagnosed Wilson's disease in a 17-year-old male patient 6 years after his first episode of gross hematuria and 2 years after detection of hypercalciuria and nephrocalcinos...

journal_title：Nephron

authors： Hoppe B,Neuhaus T,Superti-Furga A,Forster I,Leumann E

更新日期：1993-01-01 00:00:00

abstract：:Obstructed shunt vessels were studied immunohistochemically to clarify the mechanism of shunt obstruction in hemodialysis patients. The subjects were 12 hemodialysis patients with shunt obstruction, and 8 patients newly started on hemodialysis were used as the controls. Cryosections of shunt tissue were prepared and s...

journal_title：Nephron

authors： Taniguchi Y,Yorioka N,Yamashita K,Masaki T,Yamakido M

更新日期：1999-01-01 00:00:00

abstract：:In order to elucidate the mechanism of peritoneal dialysis fluid inhibition of cell functions, laboratory-prepared fluids were used to investigate the specific influences of low pH and high lactate concentration on neutrophil viability, phagocytosis, respiratory burst activation and leukotriene B4 (LTB4) generation. I...

journal_title：Nephron

authors： Liberek T,Topley N,Jörres A,Petersen MM,Coles GA,Gahl GM,Williams JD

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Icodextrin, an effective osmotic substance that has been proposed as an alternative agent for peritoneal dialysis induces ultrafiltration over long dwells. This study examines the peritoneal transport after exposure to Icodextrin in rats. METHODS:Animals were divided in 4 groups and injected daily for 30 da...

journal_title：Nephron

authors： Frajewicki V,Kushnir D,Wajsbrot V,Kohan R,Shostak A,Gotloib L

更新日期：2002-09-01 00:00:00

abstract：:Previous work has shown that cigarette-smoking affects platelets and endothelium in men and women without renal failure. The present study compared 10 male habitual smokers receiving maintenance hemodialysis for chronic renal failure with 11 healthy male habitual smokers before and after controlled cigarette-smoking a...

journal_title：Nephron

authors： Davis JW,Arnold J,Wiegmann T

更新日期：1993-01-01 00:00:00

abstract：:This study sought to determine if low doses of ciclosporin (CS) designed to give fasting serum levels of 50-100 ng/ml achieve effective immunosuppression when used from the early postoperative period after renal transplantation. Ninety-four primary renal transplant recipients were studied. Group 1 patients were treate...

journal_title：Nephron

authors： Brady HR,Kamel KS,Harding ME,Cook GT,deVeber GA,Cardella CJ

更新日期：1990-01-01 00:00:00

abstract：:A gradual loss of cell viability was observed during in vitro incubation of peritoneal cells from chronically uremic mice in commercial peritoneal dialysis solutions. The magnitude of this cytotoxicity toward peritoneal cells harvested from uremic mice and controls was comparable. Resident peritoneal cells were always...

journal_title：Nephron

authors： Gallimore B,Gagnon RF,Stevenson MM

更新日期：1986-01-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) to undergo spontaneous and induced interleukin-1 (IL-1) production was examined in 10 healthy controls and in 10 patients undergoing intermittent hemodialysis (HD) using cuprophane membranes. Extracellular and cytoplasmic IL-1 activity was assayed by biologic a...

journal_title：Nephron

authors： Blumenstein M,Schmidt B,Ward RA,Ziegler-Heitbrock HW,Gurland HJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：:We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

journal_title：Nephron

authors： Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. METHODS:We performed an observational study on patients (≥18 years old) who had been on HD for ...

journal_title：Nephron

authors： Lim Y,Yang G,Cho S,Kim SR,Lee YJ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of treatment for renal anemia in patients with chronic kidney disease (CKD). This meta-analysis was designed to evaluate their efficacy and safety. METHOD:Eight databases were searched for randomized controlled trials (RCTs). ...

journal_title：Nephron

authors： Wen T,Zhang X,Wang Z,Zhou R

更新日期：2020-01-01 00:00:00

abstract：:We report a case of visceral leishmaniasis in a 38-year-old renal transplant recipient living in an endemic country. Antimonial derivatives induced a rapid remission. A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases. We suggest that the specific immunosuppressi...

journal_title：Nephron

authors： Moulin B,Ollier J,Bouchouareb D,Purgus R,Olmer M

更新日期：1992-01-01 00:00:00

abstract：:Renin substrate concentrations and the release of renin in response to the rapid removal of 15 ml/kg weight blood or subcutaneous administration of 500 microgram/kg body weight isoproterenol were measured in control rats and animals recovering from prior myohemoglobinuric acute renal failure (recovery rats). Blood for...

journal_title：Nephron

authors： Carvalho JS,Landwehr DM,Oken DE

更新日期：1978-01-01 00:00:00

abstract：INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...

journal_title：Nephron

authors： Covic AC,Sprague SM,Rastogi A,Ketteler M,Walpen S,Perrin A,Floege J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the FAM20A gene result in amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether ...

journal_title：Nephron

authors： Koruyucu M,Seymen F,Gencay G,Gencay K,Tuna EB,Shin TJ,Hyun HK,Kim YJ,Kim JW

更新日期：2018-01-01 00:00:00

abstract：:Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...

journal_title：Nephron

authors： Ishikawa I

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIM:The impact of dialysis membrane permeability on neutrophil transmigration properties in vitro was examined in the present study. This issue has not been fully scrutinized before. METHODS:We studied the capacity of neutrophils collected from a group of dialysis patients randomly treated with cuprophan, l...

journal_title：Nephron

authors： Moshfegh A,Jacobson SH,Halldén G,Thylén P,Lundahl J

更新日期：2002-08-01 00:00:00

abstract：:Prolongation of repolarization dispersion (QT interval dispersion) measured from the 12-lead surface ECG has been associated with sudden cardiac death and ventricular tachyarrhythmias in a variety of cardiac disorders. The aim of our study was to assess the effects of hemodialysis (HD) and continuous ambulatory perito...

journal_title：Nephron

authors： Kantarci G,Ozener C,Tokay S,Bihorac A,Akoğlu E

更新日期：2002-08-01 00:00:00

abstract：:To reassess the reported protective effects of verapamil in renal ischaemia, we perfused the left kidney of uninephrectomized female Wistar rats with verapamil (0.1 and 1.0 mg/kg) immediately prior to clamping the renal artery for 60 min. When compared to controls, both doses of verapamil failed to afford protection w...

journal_title：Nephron

authors： Bock HA,Brunner FP,Torhorst J,Thiel G

更新日期：1991-01-01 00:00:00

abstract：:In an attempt to clarify the renal involvement induced by human parvovirus B19 (HPB19) infection, we investigated 6 adult patients with transient urinary abnormalities followed by erythema infectiosum. All patients had HPB19-specific IgM antibody and showed mild proteinuria of 0.2-1.2 g/day with or without microscopic...

journal_title：Nephron

authors： Takeda S,Takaeda C,Takazakura E,Haratake J

更新日期：2001-11-01 00:00:00

abstract：:Ischemic renal failure was produced in rabbits by occluding the renal arteries for 90 min. Group 1 (n = 8) received radiocontrast media at the time of occlusion, group 2 (n = 8) 24 h after occlusion, and group 3 (n = 8) 3 days after occlusion. Group 4 (n = 12) was subjected to ischemic injury alone, group 5 (n = 4) se...

journal_title：Nephron

authors： Schultz SG,Lavelle KJ,Swain R

更新日期：1982-01-01 00:00:00

abstract：:The effect of water immersion to the neck on renal calcium and magnesium handling was studied in 11 nephrotic patients. There was an increase in the urinary excretion of both calcium and magnesium on immersion, and a return towards preimmersion control values in the hour following immersion. Clearances of calcium and ...

journal_title：Nephron

authors： Brown C,Sutton JV,Adler A,Feinroth MV,Feinroth M,Friedman EA,Berlyne GM

更新日期：1983-01-01 00:00:00