Parathyroidectomy in chronic renal failure.

Abstract:

:Parathyroidectomy was carried out in 26 patients over a 14-year period. Excellent results were obtained in patients with severe hyperparathyroidism. Vascular calcification, hypercalcaemia and pruritus did not justify surgery unless associated with unequivocal hyperparathyroidism. 13 patients required intravenous calcium infusion for up to 2 weeks to control post-operative hypocalcaemia. Calcium requirements could be predicted from the pre-operative plasma alkaline phosphatase level. Following operation continued treatment with vitamin D was necessary to prevent hypocalcaemia. Hyperparathyroidism recurred in 1 patient after 8 years and 4 patients developed osteomalacia. Since parathyroid hormone may have toxic effects other than those on bone, maintenance of normal levels should be a long-term objective in the treatment of patients with chronic renal failure. Where large parathyroid glands are present, surgical reduction in gland mass is a logical prelude to long-term suppression of parathyroid hormone with vitamin D and phosphate-binding agents.

journal_name

Nephron

journal_title

Nephron

authors

Dawborn JK,Brown DJ,Douglas MC,Eddey HH,Heale WF,Thomas DP,Xipell JM

doi

10.1159/000182921

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

100-5

issue

2

eissn

1660-8151

issn

2235-3186

journal_volume

33

pub_type

杂志文章

相关文献

NEPHRON文献大全
  • A blind controlled trial of phase-contrast microscopy by two observers for evaluating the source of haematuria.

    abstract::Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000184011

    authors: Venkat Raman G,Pead L,Lee HA,Maskell R

    更新日期:1986-01-01 00:00:00

  • Nephropathy and mixed cryoglobulinemia: evidence for an immune complex pathogenesis.

    abstract::Mixed IgM-IgG cryoglobulins were present in the serum of a patient with the nephrotic syndrome, recurrent purpura, chronic active hepatitis and ascites. A renal biopsy demonstrated deposition of IgM, IgG, and complement components C3 and C4 in intracapillary 'coagula' and glomerular capillary walls. No glomerular depo...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180591

    authors: Zimmerman SW,Dreher WH,Burkholder PM,Goldfarb S,Weinstein AB

    更新日期:1976-01-01 00:00:00

  • Effect of sodium bicarbonate preloading on ischemic renal failure.

    abstract::Rats pretreated with sodium bicarbonate were functionally protected from the damage of bilateral renal artery occlusion. The rise in serum creatinine (day 1 minus day 0) during the first 24 h after ischemia was 2.88 +/- 0.28 mg% in the bicarbonate-loaded animals versus 3.90 +/- 0.26 mg% in their matched controls (p le...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000183915

    authors: Atkins JL

    更新日期:1986-01-01 00:00:00

  • Blood leukocyte contribution to serum ferritin levels in patients on chronic hemodialysis.

    abstract::Serum ferritin level has been shown by many investigators to be a good indicator of bone marrow iron stores in normal subjects. Although this correlation may hold in some pathological situations, it is lost in others. In leukemia a dissociation has been observed between serum ferritin levels and bone marrow iron store...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000186241

    authors: Nuwayri-Salti N,Jabre F,Saab G,Daouk M,Salem Z

    更新日期:1991-01-01 00:00:00

  • Factors inducing post-obstructive diuresis in rats.

    abstract::1 day after bilateral ureteral occlusion (BUO), the extracellular fluid (ECF) volume of rats was increased by 2.8 ml/100 g body weight above those values observed after either a sham operation or after 1 day of unilateral ureteral occlusion (UUO). The plasma urea concentration of BUO rats averaged about five times the...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000183293

    authors: Sophasan S,Sorrasuchart S

    更新日期:1984-01-01 00:00:00

  • Urine osmolarity predicts the body weight-reduction response to tolvaptan in chronic kidney disease patients: a retrospective, observational study.

    abstract:BACKGROUND/AIMS:Tolvaptan, a vasopressin V2 receptor antagonist, promotes the excretion of electrolyte-free water. Patients with heart failure or liver cirrhosis, whose urine osmolarity is high due to increased vasopressin, show a good response to tolvaptan; however, it remains dubious whether tolvaptan is also effecti...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000381859

    authors: Iwatani H,Kawabata H,Sakaguchi Y,Yamamoto R,Hamano T,Rakugi H,Isaka Y

    更新日期:2015-01-01 00:00:00

  • Circulating immune complexes during various forms of renal allograft rejection episodes.

    abstract::Previous reports on the nephritogenic and immunological enhancing capacity of posttransplant circulating immune complexes (CICs) are conflicting and have been confined to the study of acute rejection episode (AR). This study was undertaken to assess the nephritogenicity of CICs in patients undergoing accelerated acute...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182633

    authors: Jordan SC,Sakai R,Ettenger RB,Fine RN

    更新日期:1982-01-01 00:00:00

  • Response to parenteral iron with and without androgen therapy in patients undergoing regular haemodialysis.

    abstract::The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000180751

    authors: von Hartitzsch B,Kerr DN

    更新日期:1976-01-01 00:00:00

  • Glomerular deposition of alpha 2-macroglobulin in a child with steroid refractory nephrotic syndrome.

    abstract::A four-year-old male with steroid refractory nephrotic syndrome was found to have diffuse deposition of alpha 2-macroglobulin (alpha 2M) in the glomeruli which showed diffuse mesangial proliferation and partial hyalinization by light microscopy. Camostat mesylate, a commercially available synthetic proteinase inhibito...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000186874

    authors: Asami T,Ohsawa S,Tomisawa S,Hashimoto K,Toyabe S,Sakai K

    更新日期:1992-01-01 00:00:00

  • Cytoprotective effect of ulinastatin on LLC-PK1 cells treated with antimycin A, gentamicin, and cisplatin.

    abstract::The cytoprotective effect of ulinastatin was studied in LLC-PK1 cells treated with antimycin A, gentamicin, or cisplatin. All of the three agents induced a concentration-dependent increase in the release of lactate dehydrogenase and a decrease in the amount of remaining protein. In the cell injury models treated with ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000190195

    authors: Ishibashi M,Yamasaki F,Nakakuki M,Shinkawa T,Mizota M

    更新日期:1997-01-01 00:00:00

  • COVID-19 in Renal Transplant Recipients: Case Series and a Brief Review of Current Evidence.

    abstract::By April 26, 2020, infections related to coronavirus disease 2019 (COVID-19) affected people from 210 countries and caused 203,818 reported deaths worldwide. A few studies discussed the outcome of COVID-19 in kidney transplant recipients. This short series demonstrates our experience in managing COVID-19 disease in re...

    journal_title:Nephron

    pub_type:

    doi:10.1159/000512329

    authors: Elhadedy MA,Marie Y,Halawa A

    更新日期:2020-12-08 00:00:00

  • Renin release and the refractoriness to acute renal failure of rats recovering from prior renal failure.

    abstract::Renin substrate concentrations and the release of renin in response to the rapid removal of 15 ml/kg weight blood or subcutaneous administration of 500 microgram/kg body weight isoproterenol were measured in control rats and animals recovering from prior myohemoglobinuric acute renal failure (recovery rats). Blood for...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181429

    authors: Carvalho JS,Landwehr DM,Oken DE

    更新日期:1978-01-01 00:00:00

  • Hemodialysis Patients Display a Declined Proportion of Th2 and Regulatory T Cells in Parallel with a High Interferon-γ Profile.

    abstract:BACKGROUND:A high prevalence of cardiovascular diseases (CVDs) and infections in patients with chronic kidney disease (CKD) arises partly due to a high inflammatory state and aberrations in immune cells function. Following in vitro stimulation of leukocytes with different T-cell mitogens, we observed a lower level of i...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000471814

    authors: Mansouri L,Nopp A,Jacobson SH,Hylander B,Lundahl J

    更新日期:2017-01-01 00:00:00

  • Renal histologic and ultrastructural findings in psychogenic polydipsia and diabetes insipidus.

    abstract::The renal biopsies of 15 patients affected by polydipsia syndromes were examined under light and electron microscopes. The authors contend that the observed renal lesions (dilatation of the glomerular loops, tubular hypertrophy and vacuolization, and basal membrane swelling) are the morphologic result of tubular hyper...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180606

    authors: Naccarato R,Rizzo A,Sirigu F,Bertaglia E,Previato G,Fiaschi E

    更新日期:1976-01-01 00:00:00

  • Effect of dialysis on circulating Na,K ATPase inhibitor in uremic patients.

    abstract::Deproteinized plasma from patients with renal failure had an inhibitory effect on Na,K ATPase activity measured in vitro by a linked-enzyme assay. No inhibitory effect was observed with plasma from normal subjects or from patients undergoing chronic ambulatory peritoneal dialysis. The inhibition of Na,K ATPase whether...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185832

    authors: Stokes GS,Norris LA,Marwood JF,Johnston H,Caterson RJ

    更新日期:1990-01-01 00:00:00

  • Hypomagnesemia following the diuresis of post-renal obstruction and renal transplant.

    abstract::Three unusual cases are described which demonstrated hypomagnesemia and symptoms resembling magnesium deficiency syndrome. The hypomagnesemia was most likely secondary to urinary losses from diuresis following release of post-renal obstruction and renal homotransplantation. Heretofore, this association has not been de...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180457

    authors: Davis BB,Preuss HG,Murdaugh HV Jr

    更新日期:1975-01-01 00:00:00

  • Onset, time course, and persistence of increased haemodialysis-induced breath isoprene emission.

    abstract::Recent findings of increased isoprene emission in the exhaled breath of patients undergoing haemodialysis and experimental evidence of the potential toxic and cancerogenic effects of isoprene hydrocarbon led us to assess how long haemodialysis patients are exposed to how much isoprene after a single haemodialysis sess...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045958

    authors: Trovarelli G,Brunori F,De Medio GE,Timio M,Lippi G,Pelli MA,Capodicasa E

    更新日期:2001-05-01 00:00:00

  • Effect of fructose and mannitol on dog renal cortical adenine nucleotide content, in vivo.

    abstract::The renal cortex of anesthetized dogs was found to contain per gram lyophilized dry weight 9.5+/-0.6 micronmol ATP, 3.2+/-0.5 MICRONMOL ADP, 0.68+/-0.3 MICRONMOL AMP, and 22.5+/-4.4 micronmol Pi. These amounts were unchanged by the administration of moderate amounts of saline or hypertonic mannitol in load doses of ab...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180833

    authors: Urbaitis BK,Blake WD

    更新日期:1977-01-01 00:00:00

  • Effects of incubation at various 'room' temperatures on the sensitivity and specificity of Microstix-3.

    abstract::The feasibility of room temperature incubation of Microstix-3 specimens to detect urinary tract infection was studied. This procedure, if successful, would allow home monitoring of patients and eliminate the need for an incubator. Four Microstix-3 strips were dipped into each of 1,241 urine specimens and incubated at ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182640

    authors: Akriotis VJ,Arbus GS

    更新日期:1982-01-01 00:00:00

  • Proliferative glomerulonephritis in monoclonal gammopathy.

    abstract::A 62-year-old white male suffering from plasmacytosis with monoclonal gammopathy developed gastrointestinal bleeding, microscopic hematuria, proteinuria and progressive azotemia. A renal biopsy demonstrated capillary wall thickening, mesangial hyperplasia, crescent formation and subepithelial humps. Serum immunoglobul...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180902

    authors: Dhar SK,Smith EC,Fresco R

    更新日期:1977-01-01 00:00:00

  • Exercise renal rehabilitation program: psychosocial effects.

    abstract::The aim of this study was to assess the psychosocial effects of exercise training on hemodialysis (HD) patients. Thirty-one uremic patients, aged 50.6+/-11.6 years, on maintenance HD were studied. Twenty patients were selected at random for a 6-month exercise renal rehabilitation program (ERRP) consisting of 3 weekly ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000190266

    authors: Kouidi E,Iacovides A,Iordanidis P,Vassiliou S,Deligiannis A,Ierodiakonou C,Tourkantonis A

    更新日期:1997-01-01 00:00:00

  • Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.

    abstract::The methylenetetrahydrofolate reductase (MTHFR) gene polymorphism has been shown to be associated with cardiovascular disease in healthy subjects as well as in patients with end-stage renal disease (ESRD). In this study, we examined the allelic frequency and genotype distribution of the MTHFR gene in 151 Chinese ESRD ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045922

    authors: Lim PS,Hung WR,Wei YH

    更新日期:2001-03-01 00:00:00

  • Role of secondary hyperparathyroidism in the development of post-transplant acute tubular necrosis.

    abstract::Post-transplant cure tubular necrosis (ATN) represents the most frequent cause of delayed graft function in the immediate post-transplant period. Several causes have been associated with the development of post-transplant ATN such as donor and recipient ages, cold-warm ischemia times, HLA mismatches, and postoperative...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000189002

    authors: Torregrosa JV,Campistol JM,Fenollosa B,Montesinos M,Romar A,Martinez de Osaba MJ

    更新日期:1996-01-01 00:00:00

  • Failure of sodium restriction to abolish exaggerated natriuresis in poststreptococcal glomerulonephritis.

    abstract::Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis. Five patients were studied before and after 1 week of dietary sodium restriction in order to examine the possibility that increased extrac...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180852

    authors: Schacht RG,Steele JM Jr,Lowenstein J,Baldwin DS

    更新日期:1977-01-01 00:00:00

  • Uremic pruritus and skin mast cells.

    abstract::The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000186826

    authors: Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

    更新日期:1992-01-01 00:00:00

  • Urinary excretion rate of guanidinoacetic acid as a new marker in hypertensive renal damage.

    abstract::This study was undertaken to evaluate the relation between the urinary excretion of guanidinoacetic acid (GAA) and other substances in hypertensive patients (6 with borderline hypertension and 29 with hypertension) and 12 normal controls. In 10 of the hypertensive patients, GAA was measured before and after 4 weeks of...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185656

    authors: Takano Y,Aoike I,Gejyo F,Arakawa M

    更新日期:1989-01-01 00:00:00

  • Total Calcium and Albumin Are Decreased in the Deeper Epidermis of Patients with Chronic Kidney Disease-Associated Pruritus.

    abstract:BACKGROUND/AIMS:In our earlier studies, we reported high concentrations of intra- and extracellular calcium ions (Ca2+) in the deeper epidermis of patients with chronic kidney disease (CKD) and associated pruritus. To determine the cause of this phenomenon, we measured total calcium (TCa) concentrations in the deeper e...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000458417

    authors: Momose A,Shiraiwa Y,Narita S,Kusumi T,Goto S,Sera K

    更新日期:2017-01-01 00:00:00

  • The importance of osmolality fall and ultrafiltration rate on hemodialysis side effects. Influence of intravenous mannitol.

    abstract::The decreases in serum osmolality as well as the rate of ultrafiltration during hemodialysis and the influence of each upon the side effects of this treatment were studied in 13 chronic stable dialysis patients. Mannitol (9 mosm/kg water) was infused in two out of four dialyses, in a double blind fashion. A solution o...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000182039

    authors: Rosa AA,Shideman J,McHugh R,Duncan D,Kjellstrand CM

    更新日期:1981-01-01 00:00:00

  • Minimal-change nephrotic syndrome in adults treated with alternate-day steroids.

    abstract::Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000184494

    authors: Nair RB,Date A,Kirubakaran MG,Shastry JC

    更新日期:1987-01-01 00:00:00

  • Kidney and calcitonin.

    abstract::Calcitonin, whatever its origin, produces a decrease in the renal tubular reabsorption of sodium, phosphate and calcium in man and in the rat. Renal receptors for calcitonin have been demonstrated in the membranes of rat tubular cells using 125I salmon calcitonin as a tracer. Hormone-receptor interaction initiates the...

    journal_title:Nephron

    pub_type: 杂志文章,评审

    doi:10.1159/000180515

    authors: Ardaillou R

    更新日期:1975-01-01 00:00:00