Uremic pruritus and skin mast cells.

Abstract:

:The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group B, 12 patients without pruritus. Controls were 6 age- and sex-matched healthy subjects. In comparison with patients without pruritus, patients with pruritus had mainly degranulated, diffusely spread and more numerous mast cells in the skin; significantly higher levels of plasma middle molecular weight substances, serum histamine and PTH and significantly lower serum iron levels. However, no differences were noted in observed parameters between groups on different treatment modalities. Favorable therapeutic effects in patients with pruritus were achieved either with iron supplementation in those with hypoferremia or with antihistamines, mast cell membrane stabilizers and high-permeability membranes.

journal_name

Nephron

journal_title

Nephron

authors

Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

doi

10.1159/000186826

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

5-9

issue

1

eissn

1660-8151

issn

2235-3186

journal_volume

61

pub_type

杂志文章

相关文献

NEPHRON文献大全
  • Morphine modulates mesangial immunoglobulin G uptake in rats with antithymocyte serum-induced mesangial cell injury.

    abstract::The glomerular mesangium is an important site of activity in patients with heroin addiction. We studied the effect of morphine, a metabolite of heroin, on the mesangial immunoglobulin G aggregate uptake in a model of specific mesangial cell injury. Isolated specific mesangial cell injury was developed in Lewis rats by...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000189301

    authors: Singhal PC,Pan CQ,Sagar S,Valderrama E,Stahl RA

    更新日期:1996-01-01 00:00:00

  • Obesity and hypertension.

    abstract::Most hypertensive subjects are overweight, and as a consequence have an increased prevalence of hypercholesterolaemia, impaired glucose tolerance, and left ventricular hypertrophy. Reduction of the blood pressure by antihypertensive drugs without control of the obesity leaves these additional risk factors for cardiova...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000184543

    authors: Ramsay LE

    更新日期:1987-01-01 00:00:00

  • Receptor-mediated endocytosis of low-density lipoprotein by cultured human glomerular cells.

    abstract::Lipoproteins might be involved in the pathogenesis of glomerular damage. Uptake of low-density lipoprotein (LDL) by cultured human glomerular cells has been studied using LDL, labelled with the fluorescent probe 1,1'-dioctadecyl-3,3,3'3'-tetramethyl-indocarbocyanine perchlorate (diI). Cells have been characterised usi...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185978

    authors: Rayner HC,Horsburgh T,Brown SL,Lavender FL,Winder AF,Walls J

    更新日期:1990-01-01 00:00:00

  • Differences between blood flow as indicated by the hemodialysis blood roller pump and blood flow measured by an ultrasonic sensor.

    abstract:BACKGROUND/AIM:The ultrasonic transit time is currently the best method for measuring the blood flow rate in the extracorporeal hemodialysis circuit. The purpose of this study was to analyze the differences between blood flow as indicated by the hemodialysis blood roller pump (prescribed blood flow) and by an ultrasoni...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000045647

    authors: Teruel JL,Fernández Lucas M,Marcén R,Rodríguez JR,López Sánchez J,Rivera M,Liaño F,Ortuño J

    更新日期:2000-06-01 00:00:00

  • A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism.

    abstract::A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism, presenting severe hyponatremia, is described. A 57-year-old man complaining of nausea, vomiting and fatigability was admitted to our hospital because of hyponatremia (114 mEq/I). The low levels of serum cortisol and urinary 17-OHCS suggested gluc...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000189056

    authors: Okada K,Takahashi S

    更新日期:1996-01-01 00:00:00

  • High Serum Sclerostin Levels Are Associated with a Better Outcome in Haemodialysis Patients.

    abstract:BACKGROUND:Sclerostin is an osteocyte hormone that decreases osteoblastogenesis. Sclerostin may play a key role in osteoporosis and also in vascular calcification (VC). In chronic kidney disease and haemodialysis (HD) patients, serum sclerostin levels are high. AIM:To assess the correlation of serum sclerostin levels ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000443845

    authors: Jean G,Chazot C,Bresson E,Zaoui E,Cavalier E

    更新日期:2016-01-01 00:00:00

  • Blood and peritoneal levels of endothelin in continuous ambulatory peritoneal dialysis patients.

    abstract::We have determined the plasma levels of endothelin-1 (ET-1) in patients with end-stage renal disease treated with continuous ambulatory peritoneal dialysis (CAPD). In 10 CAPD patients mean plasma ET levels (7.01 +/- 0.5 pg/ml) were found higher than in normal subjects (3.6 +/- 0.6 pg/ml). Peritoneal clearance of ET-1 ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000188469

    authors: Vlassopoulos D,Deray G,Carayon A,Maistre G,Jacobs C

    更新日期:1995-01-01 00:00:00

  • Serum aluminium level in the veneto chronic haemodialysis population: cross-sectional study on 1,026 patients.

    abstract::A total of 1,026 patients undergoing haemodialysis as the only chronic treatment were studied in all the dialysis units of the Veneto region, Italy. Aluminium was determined in water, dialysis fluids, and patients' serum. Aluminium mean concentration was 9.1 micrograms/l in tap water and 13.3 and 15.7 micrograms/l in ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185381

    authors: Piccoli A,Andriani M,Mattiello G,Nordio M,Modena F,Dalla Rosa C

    更新日期:1989-01-01 00:00:00

  • Angiography with nonionic X-ray contrast media in severe chronic renal failure: renal function and contrast retention.

    abstract::The effects of contrast media on renal function and the cortical retention of contrast media after abdominal angiography were investigated. Sixteen nondiabetic patients with predialytic chronic renal failure received either the nonionic dimeric contrast medium iodixanol or the monomeric contrast medium iohexol in a do...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000189139

    authors: Jakobsen JA,Berg KJ,Kjaersgaard P,Kolmannskog F,Nordal KP,Nossen JO,Rootwelt K

    更新日期:1996-01-01 00:00:00

  • Multiple myeloma presenting as dense deposit disease. Light chain nephropathy.

    abstract::A 45-year-old male was admitted to the hospital because of polyuria and polydipsia. After admission, proteinuria and hematuria were found. The kidney function deteriorated and necessitated the initiation of chronic hemodialysis. Examination of the bone marrow revealed multiple myeloma and kappa light chains were found...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182980

    authors: Knobler H,Kopolovic J,Kleinman Y,Rubinger D,Silver J,Friedlaender MM,Popovtzer MM

    更新日期:1983-01-01 00:00:00

  • Serum glycoprotein: glycosyl transferase activity in patients with renal disease.

    abstract::Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000180711

    authors: Kirschbaum BB

    更新日期:1976-01-01 00:00:00

  • Association between Ultrafiltration Rate and Clinical Outcome Is Modified by Muscle Mass in Hemodialysis Patients.

    abstract:BACKGROUND:The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. METHODS:We performed an observational study on patients (≥18 years old) who had been on HD for ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000509350

    authors: Lim Y,Yang G,Cho S,Kim SR,Lee YJ

    更新日期:2020-01-01 00:00:00

  • A new kindred with hereditary hypophosphatemic rickets with hypercalciuria: implications for correct diagnosis and treatment.

    abstract::Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a new autosomal form of hypophosphatemic rickets, recently described. This disease is characterized, and differs from other forms of hereditary hypophosphatemic rickets and/or osteomalacia by increased serum levels of 1,25-dihydroxyvitamin D, hypercalci...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000187029

    authors: Tieder M,Arie R,Bab I,Maor J,Liberman UA

    更新日期:1992-01-01 00:00:00

  • Low molecular weight heparin in hemodialysis patients with a bleeding tendency.

    abstract::Efficacy and safety of a low-molecular-weight heparin (LMWH) were studied in 33 stable maintenance hemodialysis patients who had a bleeding tendency on unfractionated heparin. The optimal dose of LMWH for each patient was titrated before the study; the mean total LMWH dosage was 1,152 +/- 574 IU. No major bleeding or ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000045840

    authors: Leu JG,Chiang SS,Lin SM,Pai JK,Jiang WW

    更新日期:2000-12-01 00:00:00

  • Clinical features and severity of nonspecific symptoms in dialysis patients.

    abstract::Nonspecific symptoms are common in dialysis patients but few methods are available to measure their severity and their response to alteration in dialysis therapy. To determine the clinical features and measure the severity of the most important symptoms in end-stage renal disease (ESRD) patients, 97 dialysis patients ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000185141

    authors: Parfrey PS,Vavasour HM,Henry S,Bullock M,Gault MH

    更新日期:1988-01-01 00:00:00

  • Hemodialysis-associated neutropenia and hypoxemia: the effect of dialyzer membrane materials.

    abstract::The fall in white blood cells (WBC) and arterial oxygen pressure that occurs during hemodialysis was investigated as a function of different dialysis membranes and different sterilization methods. 8 chronic hemodialysis patients were studied and each was dialyzed with three different membranes: cellulosic hollow fiber...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182728

    authors: Hakim RM,Lowrie EG

    更新日期:1982-01-01 00:00:00

  • Biochemistry and pathophysiology of vanadium.

    abstract::The biochemistry and function of vanadate and its possible role in health as well as in disease remains one of the most fascinating stories in biology. This review has surveyed the pertinent literature regarding its effect in the normal kidney and other tissues. While inhibition of the Na(+)-K+ ATPase enzyme was the f...

    journal_title:Nephron

    pub_type: 社论,评审

    doi:10.1159/000187913

    authors: Dafnis E,Sabatini S

    更新日期:1994-01-01 00:00:00

  • Relationship of sympathetic nervous system tone and blood pressure.

    abstract::Plasma concentrations of norepinephrine (NE) appear to reflect sympathetic nervous system (SNS) tone. Plasma NE increases substantially when the SNS is stressed by acute postural change or physical exercise. Standing up from the recumbent position elevates NE by about 90% in healthy normotensive and hypertensive subje...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181614

    authors: Lake CR

    更新日期:1979-01-01 00:00:00

  • Cell characteristics of cultured glomeruli from different animal species.

    abstract::A modified sieving technique has been developed to isolate pure glomeruli from monkey, sheep, dog, rabbit and rat kidney. Glomeruli from all these species have been grown in tissue culture and the glomerular cell outgrowth studied by light microscopy and time-lapse cinemicroscopy. The pattern of growth was the same fo...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181513

    authors: Holdsworth SR,Glasgow EF,Atkins RC,Thomson NM

    更新日期:1978-01-01 00:00:00

  • Parathyroid hormone plasma level in untreated chronic renal failure and in hemodialyzed patients.

    abstract::In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000180720

    authors: Fuss M,De Backer M,Brauman J,Nijs-Dewolf N,Manderlier T,Brauman H,Corvilain J

    更新日期:1976-01-01 00:00:00

  • 5-year follow-up of patients successfully transplanted after immunoadsorption to remove anti-HLA antibodies.

    abstract::The function of renal allografts in patients who had received pretransplant immunoadsorption in order to remove cytotoxic anti-HLA antibodies was studied. We reviewed 6 patients who received a graft which functioned beyond 3 months; the mean follow-up period was 76 (range 62-89) months. Two grafts have been lost from ...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000189281

    authors: Higgins RM,Bevan DJ,Vaughan RW,Phillips AO,Snowden S,Bewick M,Scoble JE,Hendry BM

    更新日期:1996-01-01 00:00:00

  • Urinary angiotensin II: a marker of renal tissue activity?

    abstract::The methodology for the collection, extraction, separation and measurement of urinary angiotensin II [the octapeptide, ANG(1-8)] is described. To determine the origin of urinary ANG(1-8), mean arterial pressure, renal hemodynamics and the arterial, renal venous and urinary concentrations of ANG(1-8) were examined prio...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000188215

    authors: Reams G,Villarreal D,Wu Z,Bauer JH

    更新日期:1994-01-01 00:00:00

  • C-reactive protein and interleukin-6 levels are related to renal function in predialytic chronic renal failure.

    abstract:BACKGROUND:Several studies have provided convincing evidence that in apparently healthy subjects elevated serum levels of plasma C-reactive protein (CRP) are associated with an increased risk of experiencing myocardial infarction and sudden cardiac death. It has been claimed that, in dialytic patients, the hepatic synt...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000065018

    authors: Panichi V,Migliori M,De Pietro S,Taccola D,Bianchi AM,Giovannini L,Norpoth M,Metelli MR,Cristofani R,Bertelli AA,Sbragia G,Tetta C,Palla R,Colombo R

    更新日期:2002-08-01 00:00:00

  • Effect of 1alpha-hydroxycholecalciferol, 1,25-dihydroxycholecalciferol, 3 deoxy-1alpha-hydroxycholecalciferol, 24R, 25-dihydroxycholecalciferol and successful renal transplantation on calcium absorption in haemodialysis patients.

    abstract::Using a 2-hour 47Ca absorption test, significant depression of active calcium absorption was demonstrated in 48 vitamin D untreated haemodialysis patients. This malabsorption of calcium could be corrected by the daily oral administration of 1--2 microgram of 1alphaOHD3 and 1--1.5 microgram of 1,25(OH)2D3. 5 microgram ...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000181223

    authors: Pierides AM,Aljama P,Kerr DN,Scott M,Norman AW

    更新日期:1978-01-01 00:00:00

  • Reversible uremia and its effect on the glomerular filtration rate.

    abstract::As the nephron population diminishes and azotemia develops, each remaining nephron adapts and increases its function by as much as 80%. To determine whether this adaption is permanent or transient, a rat model utilizing one remnant kidney and one normal control kidney was used. In stage one, immediately after ligation...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000182879

    authors: Shankel SW,McDaniel J

    更新日期:1982-01-01 00:00:00

  • Assessment of renal function in the early stages of nephrotoxicity induced by iodinated contrast media.

    abstract::To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

    journal_title:Nephron

    pub_type: 临床试验,杂志文章

    doi:10.1159/000045488

    authors: Duan SB,Wu HW,Luo JA,Liu FY

    更新日期:1999-01-01 00:00:00

  • Blood leukocyte contribution to serum ferritin levels in patients on chronic hemodialysis.

    abstract::Serum ferritin level has been shown by many investigators to be a good indicator of bone marrow iron stores in normal subjects. Although this correlation may hold in some pathological situations, it is lost in others. In leukemia a dissociation has been observed between serum ferritin levels and bone marrow iron store...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000186241

    authors: Nuwayri-Salti N,Jabre F,Saab G,Daouk M,Salem Z

    更新日期:1991-01-01 00:00:00

  • Procainamide pharmacokinetics in patients on continuous ambulatory peritoneal dialysis.

    abstract::The pharmacokinetics of procainamide in patients on continuous ambulatory peritoneal dialysis have been studied. A mean peak plasma concentration of 3.2 +/- 0.6 microgram/ml was achieved about 2 h after a single 500-mg oral procainamide hydrochloride dose. The procainamide elimination half-life ranged from 6.1 to 15.3...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000183984

    authors: Raehl CL,Moorthy AV,Beirne GJ

    更新日期:1986-01-01 00:00:00

  • Averting the Legacy of Kidney Disease - Focus on Childhood.

    abstract::World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, wit...

    journal_title:Nephron

    pub_type: 杂志文章,评审

    doi:10.1159/000444461

    authors: Ingelfinger JR,Kalantar-Zadeh K,Schaefer F,World Kidney Day Steering Committee.

    更新日期:2016-01-01 00:00:00

  • Renal vein renin in renovascular hypertension: the experience of two Italian centers.

    abstract::A retrospective analysis of renal vein renin results has been done in 96 patients with renal artery stenosis and hypertension studied in two Italian centers (Sassari and Pisa) with respect to the outcome of either surgery or percutaneous transluminal angioplasty (PTA). In all patients the renal vein renin ratio and th...

    journal_title:Nephron

    pub_type: 杂志文章

    doi:10.1159/000184039

    authors: Rappelli A,Glorioso N,Madeddu P,Dessì-Fulgheri P,Leoni C,Fiori C,Manca GB,Sanna G,Arzilli F,Pedrinelli R

    更新日期:1986-01-01 00:00:00