Urinary excretion rate of guanidinoacetic acid as a new marker in hypertensive renal damage.

abstract：:DNA-anti-DNA cold precipitable complexes (CPC) isolated from 21 patients with systemic lupus erythematosus were tested for their ability to stimulate polymorphonuclear leukocyte (PMN) chemotaxis and to activate complement in vitro. The complexes activated complement in 20 out of 21 cases and stimulated PMN chemotaxis ...

journal_title：Nephron

authors： Losito A,Cecchini C,Pittavini L,Zampi I

更新日期：1982-01-01 00:00:00

abstract：:The purpose of the study was to investigate the effects of parathyroid hormone (PTH) infusion on antioxidant enzyme activity and lipid peroxidation of erythrocytes in five-sixths nephrectomized (Nx) rats. Five-sixths Nx rats had a higher osmotic fragility in red blood cells (RBC). Thyroparathyroidectomy (TPTX) effecti...

journal_title：Nephron

authors： Chen SM,Young TK

更新日期：1996-01-01 00:00:00

abstract：:A modified sieving technique has been developed to isolate pure glomeruli from monkey, sheep, dog, rabbit and rat kidney. Glomeruli from all these species have been grown in tissue culture and the glomerular cell outgrowth studied by light microscopy and time-lapse cinemicroscopy. The pattern of growth was the same fo...

journal_title：Nephron

authors： Holdsworth SR,Glasgow EF,Atkins RC,Thomson NM

更新日期：1978-01-01 00:00:00

abstract：:Platelet-activating factor (PAF) belongs to a new class of lipid chemical inflammatory mediators described as acetyl glyceryl ether phosphorylcholine. Although PAF has been implicated in kidney injury, its role in renal immune injury has not been clearly defined yet. We studied the levels of PAF in the plasma and urin...

journal_title：Nephron

authors： Iatrou C,Moustakas G,Antonopoulou S,Demopoulos CA,Ziroyiannis P

更新日期：1996-01-01 00:00:00

abstract：:The glomerular mesangium is an important site of activity in patients with heroin addiction. We studied the effect of morphine, a metabolite of heroin, on the mesangial immunoglobulin G aggregate uptake in a model of specific mesangial cell injury. Isolated specific mesangial cell injury was developed in Lewis rats by...

journal_title：Nephron

authors： Singhal PC,Pan CQ,Sagar S,Valderrama E,Stahl RA

更新日期：1996-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:Diseases affecting both the lung and the kidney have grave prognosis and serious diagnostic and therapeutic consequences. Here, 3 cases of pulmonary-renal syndrome caused by antiphospholipid syndrome are reported. The patients presented with dyspnea, renal insufficiency, pulmonary infiltrates on chest X-ray and areas ...

journal_title：Nephron

authors： Henning BF,Gröne HJ,Tepel M,Büchner N,Kirchner J,Zidek W

更新日期：2002-07-01 00:00:00

abstract：:An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, theref...

journal_title：Nephron

authors： Ehrenfeld M,Licht A,Stessman J,Yanko L,Rosenmann E

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Episodes of acute kidney injury (AKI) have been associated with the development of chronic kidney disease (CKD). However, follow-up pathways for patients who have survived AKI complicating critical illness are not well established. We hypothesised that patients who had AKI requiring renal replacement therapy...

journal_title：Nephron

authors： Kirwan CJ,Blunden MJ,Dobbie H,James A,Nedungadi A,Prowle JR

更新日期：2015-01-01 00:00:00

abstract：:The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...

journal_title：Nephron

authors： Kang XX,Hirano T,Oka K,Tamaki T,Sakurai E,Kaji N,Yoshida M,Kozaki M

更新日期：1991-01-01 00:00:00

abstract：:The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...

journal_title：Nephron

authors： Goligorsky MS,Chaimovitz C,Rapoport J,Zevin L,Kiryati A,Lach S

更新日期：1983-01-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：:A preparation for performance of renal clearances in the conscious dog is described. The important aspect of the technique is the use of a Pavlov sling and a specially designed restraining apparatus. Of most importance is the use of a 7 French Swan-Ganz balloon-tipped catheter for urinary bladder catheterization. The ...

journal_title：Nephron

authors： Garner D,Laks MM

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the PTH-suppressive effect of intravenous calcitriol has already been demonstrated by various studies, the precise dose-response to calcitriol has not been fully determined for uremic secondary hyperparathyroidism (2HPT). In order to investigate in detail the dose-response of intravenous calcit...

journal_title：Nephron

authors： Koshikawa S,Akizawa T,Kurokawa K,Marumo F,Sakai O,Arakawa M,Morii H,Seino Y,Ogata E,Ohashi Y,Akiba T,Tsukamoto Y,Suzuki M

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) reduce proteinuria and slow renal disease progression more effectively than other therapies in patients with chronic kidney disease (CKD). However, differences regarding efficacy and safety between these therapies rem...

journal_title：Nephron

authors： Silvariño R,Rios P,Baldovinos G,Chichet MA,Perg N,Sola L,Saona G,De Souza N,Lamadrid V,Gadola L

更新日期：2019-01-01 00:00:00

abstract：:End-stage renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease (CKD). ESRD claims many lives every year. It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the future development of CKD and ESRD. While our understanding of the pathophysiolog...

journal_title：Nephron

authors： Ó hAinmhire E,Humphreys BD

更新日期：2017-01-01 00:00:00

abstract：:Renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (RBF), glomerular filtration rate (GFR), sodium excretion (UNaV), and intrarenal distribution of blood ...

journal_title：Nephron

authors： Katz MA,Shear L

更新日期：1975-01-01 00:00:00

abstract：:During hemodialysis therapy, a large amount of water is removed from the patient's blood in a short time; however, blood pressure remains stable in most patients. As water is removed, the circulating serum proteins become more concentrated, resulting in a marked increase in the driving force which pulls water from the...

journal_title：Nephron

authors： Tabei K,Nagashima H,Imura O,Sakurai T,Asano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Tolvaptan, a vasopressin V2 receptor antagonist, promotes the excretion of electrolyte-free water. Patients with heart failure or liver cirrhosis, whose urine osmolarity is high due to increased vasopressin, show a good response to tolvaptan; however, it remains dubious whether tolvaptan is also effecti...

journal_title：Nephron

authors： Iwatani H,Kawabata H,Sakaguchi Y,Yamamoto R,Hamano T,Rakugi H,Isaka Y

更新日期：2015-01-01 00:00:00

abstract：:Peritonitis has proven to be the major deterrent to the further growth of continuous ambulatory peritoneal dialysis (CAPD) as a treatment strategy for end-stage renal disease. The correct treatment of peritonitis remains unsettled as evidenced by the presence of advocates for oral, intravenous or intraperitoneal antib...

journal_title：Nephron

authors： Harford AM,Sica DA,Tartaglione T,Polk RE,Dalton HP,Poynor W

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:Albuminuria is a risk factor for coronary artery calcification (CAC) and cardiovascular disease (CVD). Although the urine dipstick test is widely used to screen albuminuria, little is known about the association between low-grade urine dipstick albumin and CAC. The aim of this study is to investigate th...

journal_title：Nephron

authors： Song JJ,Lee KB,Hyun YY,Kim H

更新日期：2018-01-01 00:00:00

abstract：:Postnephrectomy serum has been proved to enhance proliferation of mesangial cells in culture. Studies in offspring to uninephrectomized (UNx) mothers indicate that it remains active for a long period following UNx. On the other hand, postnephrectomy renal compensatory growth in vivo is known to be completed within a s...

journal_title：Nephron

authors： Weissgarten J,Modai D,Cohn M,Berman S,Averbukh Z

更新日期：1998-01-01 00:00:00

abstract：:Differences have been postulated for the mechanism of natriuresis due to atrial natriuretic peptide (ANP), salt loading with high salt diet (HS) and acute volume expansion (AcVE), in particular between AcVE and ANP based on the observed synergism between the two. Therefore the effects of and the interaction between th...

journal_title：Nephron

authors： Reddy S,Salipan-Moore N,Mildenberger S,Willis N,Györy AZ

更新日期：1998-01-01 00:00:00

abstract：:Hyaluronic acid (HA) is a ubiquitous component of extracellular matrix. After tissue injury, HA appears in greater abundance during the inflammatory response and the phase of clearance of cell and matrix debris, before collagen production and matrix degradation. The aim of this study was to examine whether normal rat ...

journal_title：Nephron

authors： Pedagogos E,Hewitson TD,Nicholls KM,Becker GJ

更新日期：2001-08-01 00:00:00

abstract：:The effects of contrast media on renal function and the cortical retention of contrast media after abdominal angiography were investigated. Sixteen nondiabetic patients with predialytic chronic renal failure received either the nonionic dimeric contrast medium iodixanol or the monomeric contrast medium iohexol in a do...

journal_title：Nephron

authors： Jakobsen JA,Berg KJ,Kjaersgaard P,Kolmannskog F,Nordal KP,Nossen JO,Rootwelt K

更新日期：1996-01-01 00:00:00

abstract：CONTEXT:The widespread use of diuretics, potassium supplements, and medications that block renin angiotensin system puts the chronic kidney disease (CKD) population at high risk for dyskalemia, both hyperkalemia and hypokalemia. The optimal potassium level in a CKD patient is unknown. Subject of review: Two recent stud...

journal_title：Nephron

authors： Tandukar S,Fried LF

更新日期：2018-01-01 00:00:00

abstract：:The serum levels of 25-hydroxycholecalciferol, 24,25-dihydroxycholecalciferol, and 1,25-dihydroxycholecalciferol were measured simultaneously in three groups of adults with different renal function: normal (n = 24), glomerular filtration rate (GFR) greater than 70 ml/min; moderately decreased (n = 15), GFR 5-35 ml/min...

journal_title：Nephron

authors： Rickers H,Christiansen C,Christensen P,Christensen M,Rødbro P

更新日期：1985-01-01 00:00:00

abstract：:The specific lipid alterations in plasma and four different tissues, as well as the activities of plasma lecithin-cholesterol acyltransferase (LCAT) and tissue lipolytic enzymes were determined in experimental nephrotic and control rats. In nephrotic rats, the cholesterol level in the heart was significantly increased...

journal_title：Nephron

authors： Agbedana ED,Yamamoto T,Moriwaki Y,Suda M,Takahashi S,Higashino K

更新日期：1993-01-01 00:00:00

abstract：:The course of left ventricular hypertrophy was investigated in anemic hemodialysis patients treated with recombinant human erythropoietin (r-huEPO). 12 patients, aged 60.8 +/- 9.9 years (mean +/- SD) were treated for 18.8 +/- 2.7 months. Left ventricular size was estimated by echocardiography performed before treatmen...

journal_title：Nephron

authors： Zehnder C,Zuber M,Sulzer M,Meyer B,Straumann E,Jenzer HR,Blumberg A

更新日期：1992-01-01 00:00:00

abstract：:We studied the effects of oral furosemide, 80 mg/day for 7 days, on the response of urinary excretion of phosphate and cyclic AMP to exogenous parathyroid extract (PTE) in 6 normal subjects. All 6 subjects had marked increases in urinary calcium and a significant increase in urinary cyclic AMP from the control to the ...

journal_title：Nephron

authors： Fujita T,Delea CS,Bartter FC

更新日期：1985-01-01 00:00:00