Technique for the performance of repeatable renal clearances in the conscious male dog.

abstract：BACKGROUND/AIM:Interleukin-6 (IL-6) promotes the growth of renal mesangial cells. IL-6 may play a major role in such mesangial proliferation, but there has been little research on IL-6 in relation to diabetic nephropathy because of the difficulty in measuring urinary and serum IL-6 levels. Using a newly developed, high...

journal_title：Nephron

authors： Shikano M,Sobajima H,Yoshikawa H,Toba T,Kushimoto H,Katsumata H,Tomita M,Kawashima S

更新日期：2000-05-01 00:00:00

abstract：:Hypertension secondary to renal transplantation was studied in our experimental model in the rat. In this model an intravenous injection of donor strain blood into recipients of allogeneic donor kidneys prior to transplantation was used to prolong the allograft survival. A reduced renal function associated with the hy...

journal_title：Nephron

authors： de Keijzer MH,Provoost AP,van Aken M,Kort WJ,Wolff ED,Molenaar JC

更新日期：1985-01-01 00:00:00

abstract：:Efficacy and safety of a low-molecular-weight heparin (LMWH) were studied in 33 stable maintenance hemodialysis patients who had a bleeding tendency on unfractionated heparin. The optimal dose of LMWH for each patient was titrated before the study; the mean total LMWH dosage was 1,152 +/- 574 IU. No major bleeding or ...

journal_title：Nephron

authors： Leu JG,Chiang SS,Lin SM,Pai JK,Jiang WW

更新日期：2000-12-01 00:00:00

abstract：:Mitochondria contain electron-dense particles, partly composed of an amorphous form of calcium phosphate. We have used electron microscopy from percutaneous renal biopsy material to analyze mitochondrial granulation in the proximal renal tubule of nonuremic and uremic children. Based on a technique of cutting mitochon...

journal_title：Nephron

authors： Whitney JO,Goodman JR,Piel CF

更新日期：1979-01-01 00:00:00

abstract：:A very simple analytical procedure with dimethylmethylene blue as photometric reagent was applied for the evaluation of glycosaminoglycan (GAG) urinary excretions and concentrations in both sexes, calcium oxalate stone formers, and a control group. The GAG concentrations varied significantly in stone formers (males an...

journal_title：Nephron

authors： Grases F,Llompart I,Conte A,Coll R,March JG

更新日期：1994-01-01 00:00:00

abstract：:This paper reviews the control of aldosterone secretion, including the role played by hepatic metabolic clearance, ACTH, and the renin-angiotensin system, and the interrelationships of aldosterone secretion with sodium and potassium metabolism. The physiological modulations of aldosterone secretion by the upright post...

journal_title：Nephron

authors： Chan JC

更新日期：1979-01-01 00:00:00

abstract：:Acute renal failure due to tubulo-interstitial nephritis developed in a 15-year-old girl. The disease was accompanied by uveitis and an inflammatory syndrome, consisting of a markedly increased erythrocyte sedimentation rate and high serum gamma globulin levels. The nephropathy as well as the inflammatory syndrome sub...

journal_title：Nephron

authors： Vanhaesebrouck P,Carton D,De Bel C,Praet M,Proesmans W

更新日期：1985-01-01 00:00:00

abstract：:The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...

journal_title：Nephron

authors： Zachée P,Daelemans R,Pollaris P,Boogaerts MA,Lins RL

更新日期：1994-01-01 00:00:00

abstract：AIMS:There is a trend toward deferring the initiation of chronic dialysis until absolutely indicated. This strategy, however, might lead to increased uncertainties in the timing of dialysis access creation prior to dialysis onset for patients approaching end-stage renal disease (ESRD), and the impact of which on hard e...

journal_title：Nephron

authors： Chen YM,Wang YC,Hwang SJ,Lin SH,Wu KD

更新日期：2016-01-01 00:00:00

abstract：:In Wistar rats V-U reflux with distilled water and sterile saline of varying osmolar strength produces scars in the perihilar region of the kidneys in 80% of animals. Using Indian ink as a marker, rupture of the forniceal epithelium regularly followed V-U reflux. Intrapelvic pressure rose to 120 mm Hg during the reflu...

journal_title：Nephron

authors： Morgan M,Asscher AW,Moffat DB

更新日期：1976-01-01 00:00:00

abstract：:Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...

journal_title：Nephron

authors： Hsu CH,Kurtz TW

更新日期：1981-01-01 00:00:00

abstract：:A simple three-pump-based system for the performance of continuous venovenous haemodialysis is described. The method employs access to the circulation via a double-lumen catheter, and by means of a standard extracorporeal peristaltic pump the blood is circulated through a haemofiltration filter. Standard solutions for...

journal_title：Nephron

authors： Møller Jensen D,Bistrup C,Pedersen RS

更新日期：1996-01-01 00:00:00

abstract：:Tubular necrosis elicits a process of renal tissue repair characterized by an increase of cell turnover in tubular epithelium. The present study was undertaken to examine the distribution of epidermal growth factor (EGF) and/or of its larger precursor proEGF in the kidney undergoing tubular regeneration. Sprague-Dawle...

journal_title：Nephron

authors： Nonclercq D,Toubeau G,Lambricht P,Heuson-Stiennon JA,Laurent G

更新日期：1991-01-01 00:00:00

abstract：:A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...

journal_title：Nephron

authors： Kelley WN

更新日期：1975-01-01 00:00:00

abstract：:Chronic cyclosporine nephrotoxicity is characterized morphologically by cortical interstitial fibrosis. The most important collagens involved in renal fibrosis are collagen types I and III. In order to estimate the synthesis of type III and type I collagens, we analyzed serum levels of the amino-terminal propeptide of...

journal_title：Nephron

authors： Heickendorff L,Frost L,Madsen JK,Pedersen EB

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Progressive nephropathy is one of the main features of Fabry disease (FD). It has been supposed that an early phase, clinically silent disease occurs in childhood and adolescence and is characterized by glomerular hyperfiltration (HF). Surprisingly, although HF has been reported in several stu...

journal_title：Nephron

authors： Riccio E,Sabbatini M,Bruzzese D,Annicchiarico Petruzzelli L,Pellegrino A,Spinelli L,Esposito R,Imbriaco M,Feriozzi S,Pisani A,on behalf of AFFIINITY Group.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Although the PTH-suppressive effect of intravenous calcitriol has already been demonstrated by various studies, the precise dose-response to calcitriol has not been fully determined for uremic secondary hyperparathyroidism (2HPT). In order to investigate in detail the dose-response of intravenous calcit...

journal_title：Nephron

authors： Koshikawa S,Akizawa T,Kurokawa K,Marumo F,Sakai O,Arakawa M,Morii H,Seino Y,Ogata E,Ohashi Y,Akiba T,Tsukamoto Y,Suzuki M

更新日期：2002-04-01 00:00:00

abstract：:A 62-year-old woman gave clinical manifestation of liver cirrhosis. Urinary protein was false positive, no uremia was found and renal changes were entirely overlooked. Deposition of abundant lipids (globoside and ceramide trihexoside) was found in the kidneys; essentially degenerative changes of the tubular epithelia ...

journal_title：Nephron

authors： Miyasaki K

更新日期：1975-01-01 00:00:00

abstract：:Previously, we have shown that insulin binding (IB) to erythrocytes was decreased in uremic patients and that hemodialysis corrected the receptor defect. In the present study cross-incubation experiments were performed using uremic and control erythrocytes and plasma. Incubation of control erythrocytes with uremic pla...

journal_title：Nephron

authors： Milutinović S,Breyer D,Janković N,Molnar V,Stefović A,Rocić B

更新日期：1983-01-01 00:00:00

abstract：:Classic renal tubular acidosis is characterized by a primary defect in establishment of a large hydrogen ion gradient across the distal renal tubule. Thus the development of hyperchlorenic metabolic acidosis follows. In addition, hypokalemia results from renal potassium wasting secondary hyperaldosteronism from sodium...

journal_title：Nephron

authors： Chan JC

更新日期：1979-01-01 00:00:00

abstract：:Renal hemodynamics and sodium excretion were determined before and during infusion of dopamine in doses ranging from 0.25 to 8 micrograms/kg/min in healthy volunteers (n = 15) and in patients with renal disease and moderately impaired renal function (n = 21, baseline glomerular filtration rate 34-85 ml/min). While in ...

journal_title：Nephron

authors： Smit AJ,Meijer S,Wesseling H,Reitsma WD,Donker AJ

更新日期：1989-01-01 00:00:00

abstract：:Sprague-Dawley rats given gentamicin from 10 to 70 mg/kg/day for 9 days showed a linear decrease in glomerular filtration rate with increasing dose, paralleled by histologic changes of acute tubular necrosis and cast formation only at the higher doses. Nephrotoxicity was correlated with the peak, rather than trough, s...

journal_title：Nephron

authors： Sugarman A,Brown RS,Silva P,Rosen S

更新日期：1983-01-01 00:00:00

abstract：:The biochemistry and function of vanadate and its possible role in health as well as in disease remains one of the most fascinating stories in biology. This review has surveyed the pertinent literature regarding its effect in the normal kidney and other tissues. While inhibition of the Na(+)-K+ ATPase enzyme was the f...

journal_title：Nephron

authors： Dafnis E,Sabatini S

更新日期：1994-01-01 00:00:00

abstract：:HLA antigens of Japanese patients with primary glomerulopathies were determined, and the frequency of each HLA antigen was compared with that of Japanese normal controls. IgA nephropathy with HLA-DR4, idiopathic membraneous glomerulopathy with DR2, lipoid nephrosis with DRw53 and poststreptococcal glomerulonephritis w...

journal_title：Nephron

authors： Naito S,Kohara M,Arakawa K

更新日期：1987-01-01 00:00:00

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:Nonspecific symptoms are common in dialysis patients but few methods are available to measure their severity and their response to alteration in dialysis therapy. To determine the clinical features and measure the severity of the most important symptoms in end-stage renal disease (ESRD) patients, 97 dialysis patients ...

journal_title：Nephron

authors： Parfrey PS,Vavasour HM,Henry S,Bullock M,Gault MH

更新日期：1988-01-01 00:00:00

abstract：:Familial lecithin-cholesterol acyltransferase deficiency is a hereditary disorder of lipid metabolism. Lipid material is deposited in the kidneys, the glomerular capillary basement membrane is irregularly thickened, detachment and even loss of endothelial cells are seen in the glomeruli. Proteinuria was present in 8 o...

journal_title：Nephron

authors： Myhre E,Gjone E,Flatmark A,Hovig T

更新日期：1977-01-01 00:00:00

abstract：:Lipoproteins might be involved in the pathogenesis of glomerular damage. Uptake of low-density lipoprotein (LDL) by cultured human glomerular cells has been studied using LDL, labelled with the fluorescent probe 1,1'-dioctadecyl-3,3,3'3'-tetramethyl-indocarbocyanine perchlorate (diI). Cells have been characterised usi...

journal_title：Nephron

authors： Rayner HC,Horsburgh T,Brown SL,Lavender FL,Winder AF,Walls J

更新日期：1990-01-01 00:00:00

abstract：:The parathyroid gland responsiveness to hypocalcemia induced by short-term calcium-free hemodialysis in patients with insulin-dependent diabetes mellitus was investigated in comparison with 10 nondiabetic uremic patients and compared with test results from the autonomic nervous system. Diabetic patients had lower C-te...

journal_title：Nephron

authors： Heidbreder E,Götz R,Schafferhans K,Heidland A

更新日期：1986-01-01 00:00:00

abstract：:The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

journal_title：Nephron

authors： Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

更新日期：1991-01-01 00:00:00