Abstract:
:The parathyroid gland responsiveness to hypocalcemia induced by short-term calcium-free hemodialysis in patients with insulin-dependent diabetes mellitus was investigated in comparison with 10 nondiabetic uremic patients and compared with test results from the autonomic nervous system. Diabetic patients had lower C-terminal parathyroid hormone (cPTH) levels before hemodialysis than uremic control patients and showed a significantly smaller increase in cPTH during hypocalcemia. The neurological tests revealed severe disturbances of the autonomic functions in the diabetic group. In conclusion, the disturbances observed in the parathyroid secretory pattern are probably caused by gland dysfunction; it is hypothesized that the defective autonomic nervous system has an additional effect on the development of this hormonal dysfunction.
journal_name
Nephronjournal_title
Nephronauthors
Heidbreder E,Götz R,Schafferhans K,Heidland Adoi
10.1159/000183689subject
Has Abstractpub_date
1986-01-01 00:00:00pages
285-9issue
4eissn
1660-8151issn
2235-3186journal_volume
42pub_type
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