Discordant evolution of asymptomatic proteinuria in identical twins.

abstract：:In order to elucidate the mechanism of peritoneal dialysis fluid inhibition of cell functions, laboratory-prepared fluids were used to investigate the specific influences of low pH and high lactate concentration on neutrophil viability, phagocytosis, respiratory burst activation and leukotriene B4 (LTB4) generation. I...

journal_title：Nephron

authors： Liberek T,Topley N,Jörres A,Petersen MM,Coles GA,Gahl GM,Williams JD

更新日期：1993-01-01 00:00:00

abstract：:Nephrotoxic agents such as puromycin aminonucleoside (PAN) and sodium maleate (MAL) have been used to induce experimental glomerular proteinuria and tubular disease, respectively. Current studies show that PAN caused a massive loss of albumin in the urine while not affecting the excretion of the smaller, sex-dependent...

journal_title：Nephron

authors： Neuhaus OW,Flory W,Biswas N,Hollerman CE

更新日期：1981-01-01 00:00:00

abstract：:Rats pretreated with sodium bicarbonate were functionally protected from the damage of bilateral renal artery occlusion. The rise in serum creatinine (day 1 minus day 0) during the first 24 h after ischemia was 2.88 +/- 0.28 mg% in the bicarbonate-loaded animals versus 3.90 +/- 0.26 mg% in their matched controls (p le...

journal_title：Nephron

authors： Atkins JL

更新日期：1986-01-01 00:00:00

abstract：:As the nephron population diminishes and azotemia develops, each remaining nephron adapts and increases its function by as much as 80%. To determine whether this adaption is permanent or transient, a rat model utilizing one remnant kidney and one normal control kidney was used. In stage one, immediately after ligation...

journal_title：Nephron

authors： Shankel SW,McDaniel J

更新日期：1982-01-01 00:00:00

abstract：:The protective efficacy of three schedules of a recombinant hepatitis B vaccine was evaluated in 42 patients undergoing dialysis at a teaching hospital. The rate of seroconversion after vaccination was highest (82.3%) among the recipients of three 20-micrograms doses (i.e. double the conventional dose for healthy adul...

journal_title：Nephron

authors： Mitwalli A

更新日期：1996-01-01 00:00:00

abstract：:There is already a considerable amount of evidence suggesting that fibronectin (Fn) plays an important role in the pathogenic process in some forms of glomerulonephritis (GN). It has been postulated that Fn may participate in the progression or regression of glomerular diseases. The Fn is presented in the kidney as a ...

journal_title：Nephron

authors： Altunkova I,Minkova V,Belovezhdov N

更新日期：1993-01-01 00:00:00

abstract：:We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

journal_title：Nephron

authors： Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

更新日期：1985-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...

journal_title：Nephron

authors： Shaw C,Steenkamp R,Davenport A

更新日期：2015-01-01 00:00:00

abstract：:The specific lipid alterations in plasma and four different tissues, as well as the activities of plasma lecithin-cholesterol acyltransferase (LCAT) and tissue lipolytic enzymes were determined in experimental nephrotic and control rats. In nephrotic rats, the cholesterol level in the heart was significantly increased...

journal_title：Nephron

authors： Agbedana ED,Yamamoto T,Moriwaki Y,Suda M,Takahashi S,Higashino K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. METHODS:A home hemodialysis program was started in November 1998 in the University of Torino, Italy (2...

journal_title：Nephron

authors： Piccoli GB,Bermond F,Mezza E,Quaglia M,Pacitti A,Jeantet A,Segoloni GP

更新日期：2002-10-01 00:00:00

abstract：:Renal biopsy specimens obtained from patients with various chronic nephropathies were studied by immunofluorescence (IF), electron and light microscopy. Of 49 biopsies studied by IF, 22 had granular deposits of IgG and/or C3 along the basement membranes of proximal tubules while 14 had linear and 13 both linear and gr...

journal_title：Nephron

authors： Orfila C,Rakotoarivony J,Durand D,Suc JM

更新日期：1979-01-01 00:00:00

abstract：:Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...

journal_title：Nephron

authors： de Paoli Vitali E,Ricci G,Perini L,Malacarne F,Vedovato M,Guerra G,Dapporto M,Gilli P

更新日期：1996-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：:Cerebral salt-wasting syndrome (CSWS) has been regarded as a misnomer of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). We take the position that CSWS does exist and might be more common than SIADH. Differentiation between groups has been difficult because of overlapping signs, symptoms, and ...

journal_title：Nephron

authors： Maesaka JK,Gupta S,Fishbane S

更新日期：1999-06-01 00:00:00

abstract：:Dysfunction of the host defense against infection in hemodialysis (HD) patients has major clinical and socioeconomic implications. T helper type 1 (Th1) and type 2 (Th2) cytokines are implicated in regulating the immune responses and, therefore, may be involved in impaired status. The present study was designed to exa...

journal_title：Nephron

authors： Daichou Y,Kurashige S,Hashimoto S,Suzuki S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Recently, two isoforms of cyclooxygenase (COX) have been identified, a constitutive form (COX-1) and a mitogen-inducible form (COX-2). Several studies have suggested that COX is activated in renal insufficiency, but little is known about the relationship between progression of renal insufficiency and the COX...

journal_title：Nephron

authors： Horiba N,Kumano E,Watanabe T,Shinkura H,Sugimoto T,Inoue M

更新日期：2002-05-01 00:00:00

abstract：:Increasing urinary net acid (titratable acid + NH4 - HCO-3) excretion is accompanied by an increased urinary Ca excretion because of reduced renal tubular reabsorption of filtered Ca. The relationships between urinary Ca excretion rates and urinary net acid excretion rates are reviewed for data: (1) among healthy adul...

journal_title：Nephron

authors： Lemann J Jr

更新日期：1999-01-01 00:00:00

abstract：:The nature of uremic nephrocalcinosis was studied by means of X-ray microanalysis in 5/6 nephrectomized rats. The data show that calcified deposits in the renal parenchyma of uremic rats contained substantial amounts of calcium, magnesium, aluminum and silicon. Since calcificates did not reveal a uniform composition t...

journal_title：Nephron

authors： Goligorsky MS,Chaimovitz C,Rapoport J,Zevin L,Kiryati A,Lach S

更新日期：1983-01-01 00:00:00

abstract：:Hypokalemia and potassium depletion are frequent complications of amphotericin B therapy. Both ischemic and gentamicin-induced renal failure is potentiated by potassium depletion; it is, therefore, possible that amphotericin B nephrotoxicity is similarly influenced. This study evaluated whether the acute nephrotoxic r...

journal_title：Nephron

authors： Bernardo JF,Murakami S,Branch RA,Sabra R

更新日期：1995-01-01 00:00:00

abstract：:A total of 1,026 patients undergoing haemodialysis as the only chronic treatment were studied in all the dialysis units of the Veneto region, Italy. Aluminium was determined in water, dialysis fluids, and patients' serum. Aluminium mean concentration was 9.1 micrograms/l in tap water and 13.3 and 15.7 micrograms/l in ...

journal_title：Nephron

authors： Piccoli A,Andriani M,Mattiello G,Nordio M,Modena F,Dalla Rosa C

更新日期：1989-01-01 00:00:00

abstract：:The mitochondrial DNA mutation mt.3243A>G is most commonly associated with maternally inherited diabetes and deafness (MIM 52,000), but it has protean phenotypes including renal disease due to focal segmental glomerulosclerosis. We describe monozygotic twins who both harboured this mutation and developed ESRD. Althoug...

journal_title：Nephron

authors： Shand JAD,Potter HC,Pilmore HL,Cundy T,Murphy R

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The herbal medicine Sairei-to is efficacious in renal diseases where mesangial proliferation is a key event. We examined whether Sairei-to inhibits proliferation of cultured rat mesangial cells and investigated its mechanism of action. METHODS:The effect of Sairei-to on [(3)H]-thymidine incorporation stimul...

journal_title：Nephron

authors： Awazu M,Fujita H,Omori S,Hida M

更新日期：2002-01-01 00:00:00

abstract：:Blood eosinophils were counted by the counting-chamber method in 21 regular hemodialysis patients. Before dialysis, eosinophil counts were within the normal range in all patients (mean 98 cells/mm3, range 6-350). After the first 15 min of hemodialysis, with not reused coils or hollow-fiber dialysers, a significant dro...

journal_title：Nephron

authors： Bodner G,Peer G,Zakuth V,Spirer ZH,Aviram A

更新日期：1982-01-01 00:00:00

abstract：:Rat sera, 10-30 h after unilateral nephrectomy (UNI), enhance 3H-thymidine ("3H-Tdr) incorporation into DNA of incubating renal tissue from control rats. Stimulation is even greater when extracts from remaining growing kidneys 20 h after UNI are combined with sera from rats after UNI. UNI extracts, i.e., extracts from...

journal_title：Nephron

authors： Castillo O,Robertson D,Goldin H,Preuss HG

更新日期：1980-01-01 00:00:00

abstract：:Previous work has shown that cigarette-smoking affects platelets and endothelium in men and women without renal failure. The present study compared 10 male habitual smokers receiving maintenance hemodialysis for chronic renal failure with 11 healthy male habitual smokers before and after controlled cigarette-smoking a...

journal_title：Nephron

authors： Davis JW,Arnold J,Wiegmann T

更新日期：1993-01-01 00:00:00

abstract：:This study was undertaken to evaluate the relation between the urinary excretion of guanidinoacetic acid (GAA) and other substances in hypertensive patients (6 with borderline hypertension and 29 with hypertension) and 12 normal controls. In 10 of the hypertensive patients, GAA was measured before and after 4 weeks of...

journal_title：Nephron

authors： Takano Y,Aoike I,Gejyo F,Arakawa M

更新日期：1989-01-01 00:00:00

abstract：:In order to evaluate effects of metabolic acidosis on glucose metabolism in uremia, we studied, by an intravenous glucose tolerance test (IVGTT), 46 patients with severe chronic renal failure divided into three groups according to their blood bicarbonate (BB) values: group A formed by 15 patients without or with light...

journal_title：Nephron

authors： Allegra V,Mengozzi G,Martimbianco L,Vasile A

更新日期：1993-01-01 00:00:00

abstract：:Human peritoneal mesothelial cells lie on a basement membrane-like material consisting of fibronectin (FN), type I collagen (CI), type III collagen (CIII) and laminin (LA). To understand how these extracellular matrix (ECM) proteins affect mesothelial cell behavior, we investigated their effect on the adhesion and pro...

journal_title：Nephron

authors： Yen CJ,Fang CC,Chen YM,Lin RH,Wu KD,Lee PH,Tsai TJ

更新日期：1997-01-01 00:00:00

abstract：:Spontaneous allograft rupture after kidney transplantation is a rare complication usually due to an acute rejection of the interstitial type. In a 32-year-old man kidney transplantation was performed under immunosuppression with prednisolone and ciclosporin (CS). The dose of CS was 5 mg/kg body weight intravenously fo...

journal_title：Nephron

authors： Biesenbach G,Zazgornik J,Kaiser W,Grafinger P,Stuby U,Gross C,Hartl P,Brücke P

更新日期：1992-01-01 00:00:00