The herbal medicine Sairei-to inhibits proliferation of rat mesangial cells.

abstract：BACKGROUND/AIMS:Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the FAM20A gene result in amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether ...

journal_title：Nephron

authors： Koruyucu M,Seymen F,Gencay G,Gencay K,Tuna EB,Shin TJ,Hyun HK,Kim YJ,Kim JW

更新日期：2018-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) is elevated in patients with chronic renal failure (CRF) and was suggested to be one of the factors responsible for the anemic syndrome of these patients because it raises the osmotic fragility of the red blood cells (RBC). In the present study, the youngest and oldest RBC were separated from...

journal_title：Nephron

authors： Malachi T,Bogin E,Gafter U,Levi J

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:In our earlier studies, we reported high concentrations of intra- and extracellular calcium ions (Ca2+) in the deeper epidermis of patients with chronic kidney disease (CKD) and associated pruritus. To determine the cause of this phenomenon, we measured total calcium (TCa) concentrations in the deeper e...

journal_title：Nephron

authors： Momose A,Shiraiwa Y,Narita S,Kusumi T,Goto S,Sera K

更新日期：2017-01-01 00:00:00

abstract：:ExHC rats were bred from the Sprague-Dawley strain and are highly susceptible to dietary hypercholesterolemic stimuli. Although chemical and histological examination of the aorta from ExHC rats fed a diet containing 3% cholesterol, 0.6% sodium cholate and 15% olive oil (high-cholesterol diet, HCD) has been reported, r...

journal_title：Nephron

authors： Hattori M,Yamaguchi Y,Kawaguchi H,Ito K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The prevalence of subclinical atherosclerosis and the main predictors of progression of this condition in patients undergoing peritoneal dialysis (PD) have been insufficiently investigated. OBJECTIVES AND METHOD:Following a prospective, multicenter, observational design, we studied 237 patients who were tre...

journal_title：Nephron

authors： Pérez Fontán M,Borràs Sans M,Bajo Rubio MA,Rodriguez-Carmona A,Betriu A,Valdivielso JM,Fernández E,NEFRONA Study investigators.

更新日期：2017-01-01 00:00:00

abstract：:Mysterious deaths of archeologists after opening Egyptian tombs have been suspected to be secondary to inhalation of mycotoxin, however, the hypothesis has never been verified. Recently, we observed a case of acute renal failure (ARF) undeniably due to inhalation of ochratoxin of Aspergillus ochraceus. After spending ...

journal_title：Nephron

authors： Di Paolo N,Guarnieri A,Loi F,Sacchi G,Mangiarotti AM,Di Paolo M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Complement factor H (hCFH) plays a key inhibitory role in the control of the alternative complement pathway. We examined whether urinary hCFH (U-hCFH) levels is useful as an indirect indicator of renal damage. METHODS:Urine samples were obtained from 104 patients with renal disease. Urine was collected with...

journal_title：Nephron

authors： Tamano M,Fuke Y,Endo M,Ohsawa I,Fujita T,Ohi H

更新日期：2002-01-01 00:00:00

abstract：:The effects of chronic ethanol ingestion on the rat kidney were studied. Rats were fed a liquid diet containing ethanol for 5 weeks to induce chronic alcoholism. Renal ischemia was introduced by clamping the renal artery and vein either for 10 or 20 min. The glomerular filtration rate (GFR) and the renal blood flow (R...

journal_title：Nephron

authors： Ishigami M,Ohnishi ST,Chan R,Shimada Y,Yabuki S

更新日期：1989-01-01 00:00:00

abstract：:Chronic cyclosporine nephrotoxicity is characterized morphologically by cortical interstitial fibrosis. The most important collagens involved in renal fibrosis are collagen types I and III. In order to estimate the synthesis of type III and type I collagens, we analyzed serum levels of the amino-terminal propeptide of...

journal_title：Nephron

authors： Heickendorff L,Frost L,Madsen JK,Pedersen EB

更新日期：1994-01-01 00:00:00

abstract：:The urinary transforming growth factor beta (TGF-beta) excretion was measured in 33 patients including 10 with systemic lupus erythematosus (SLE), 8 with focal glomerular sclerosis (FGS), 9 with IgA nephropathy (IgAN), and 6 with membranous nephropathy (MN), and in 7 healthy subjects by enzyme-linked immunosorbent ass...

journal_title：Nephron

authors： Kanai H,Mitsuhashi H,Ono K,Yano S,Naruse T

更新日期：1994-01-01 00:00:00

abstract：:We have previously documented the importance of tumor necrosis factor (TNF) alpha in the pathogenesis of nephrotoxic-serum nephritis in rats. In this study, we evaluated the possible relevance of the well-established cytocidal TNF activity to the mechanism of glomerular injury by assessing sensitivity of rat mesangial...

journal_title：Nephron

authors： Hruby ZW,Cybulsky AV,Lowry RP

更新日期：1990-01-01 00:00:00

abstract：:A preparation for performance of renal clearances in the conscious dog is described. The important aspect of the technique is the use of a Pavlov sling and a specially designed restraining apparatus. Of most importance is the use of a 7 French Swan-Ganz balloon-tipped catheter for urinary bladder catheterization. The ...

journal_title：Nephron

authors： Garner D,Laks MM

更新日期：1976-01-01 00:00:00

abstract：:We have previously reported that hyperoxalemia can be aggravated by vitamin C supplementation in regular hemodialysis patients. The present study was undertaken to examine the validity of this observation in an experimental setting. Fifty five-sixths nephrectomized rats were divided into two groups: 30 rats were allow...

journal_title：Nephron

authors： Ono K,Ono H,Ono T,Kikawa K,Oh Y

更新日期：1989-01-01 00:00:00

abstract：:A 2-year prospective study was done in 45 patients to see whether the FENa test, done at first nephrology consultation visit for acute renal failure, was useful in prognosticating whether patients would recover renal function spontaneously or need dialysis. Of 26 patients who recovered renal function spontaneously, 8 ...

journal_title：Nephron

authors： Pru C,Kjellstrand CM

更新日期：1984-01-01 00:00:00

abstract：:The use of antimitotic chemotherapy in hemodialysis patients is not yet well codified, and each individual decision remains difficult. We report the case of a 68-year-old hemodialyzed man who developed a squamous cell carcinoma of the upper third of the esophagus. Necessarily disabling surgery was rejected, and three ...

journal_title：Nephron

authors： Rebibou JM,Chauffert B,Dumas M,Mousson C,Bone MC,Tanter Y,Rifle G

更新日期：1996-01-01 00:00:00

abstract：:Sickle cell nephropathy characterized by proteinuria and predominantly glomerular lesions has not been studied as extensively as renal tubular alterations in sickle cell disease. We reviewed our experience with this entity over a 14-year period. Of 13 children with either proteinuria or the nephrotic syndrome, 8 showe...

journal_title：Nephron

authors： Tejani A,Phadke K,Adamson O,Nicastri A,Chen CK,Sen D

更新日期：1985-01-01 00:00:00

abstract：:Renal scarring is considered to be a characteristic of reflux nephropathy. The effects of ulinastatin, a strong inhibitor of polymorphonuclear leukocyte elastase, on renal scarring following direct parenchymal or intravesical ascending infection by Serratia marcescens or Escherichia coli were determined. Four days of ...

journal_title：Nephron

authors： Matsumoto T,Haraoka M,Mizunoe Y,Takahashi K,Kubo S,Sakumoto M,Tanaka M,Kumazawa J

更新日期：1995-01-01 00:00:00

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...

journal_title：Nephron

authors： Lenz T,Thiede HM,Nussberger J,Atlas SA,Distler A,Schulte KL

更新日期：1992-01-01 00:00:00

abstract：:Dialysate effluent protein content was measured in 22 patients undergoing continuous ambulatory peritoneal dialysis (9 with and 13 without previous peritonitis). The average amount of protein in those patients without peritonitis was 1.3 g/2 liters exchanged over a 6-hour period, while that of patients with previous p...

journal_title：Nephron

authors： Katirtzoglou A,Oreopoulos DG,Husdan H,Leung M,Ogilvie R,Dombros N

更新日期：1980-01-01 00:00:00

abstract：:Clearance and in vitro microperfusion studies were performed in rabbits to determine the effect of cisplatin on proximal straight tubule transport of calcium and magnesium. Rabbits were injected with cisplatin (2.5 mg/kg i.p. once weekly) for 3 weeks, whereas control rabbits received normal saline solution which serve...

journal_title：Nephron

authors： Wong NL,Sutton RA,Dirks JH

更新日期：1988-01-01 00:00:00

abstract：:A critical survey of the literature suggests that elevated serum uric acid is definitely associated with hypertension and may function as an independent risk factor in the development of this disease. The possible role of an elevated serum uric acid as an independent risk factor for the development of ischemic heart d...

journal_title：Nephron

authors： Tweeddale MG,Fodor JG

更新日期：1979-01-01 00:00:00

abstract：:Serum concentrations of soluble interleukin 2 receptor (IL-2R) were measured in 65 hemodialysis patients and compared with serum levels of beta 2-microglobulin and tissue polypeptide antigen (TPA). Elevated IL-2R levels, found in 85% of examined patients, correlated with elevated TPA serum concentrations (p less than ...

journal_title：Nephron

authors： Walz G,Kunzendorf U,Josimovic-Alasevic O,Preuschoff L,Schwarz A,Keller F,Asmus G,Offermann G,Diamantstein T,Distler A

更新日期：1990-01-01 00:00:00

abstract：:Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination. ...

journal_title：Nephron

authors： Melappioni M,Baldassari M,Baldini S,Radicioni R,Panichi N

更新日期：1992-01-01 00:00:00

abstract：:Following successful kidney transplantation, renal anemia is gradually corrected during the first 3-4 months. Serum erythropoietin (EPO) levels are increased after the first postoperative day following grafting. In this study, the serum EPO levels in the early posttransplant phase were investigated in 8 living-donor a...

journal_title：Nephron

authors： Goch J,Birgegård G,Wikström B,Tufveson G,Danielson BG

更新日期：1992-01-01 00:00:00

abstract：:Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but ...

journal_title：Nephron

authors： Carrara C,Abbate M,Sabadini E,Remuzzi G

更新日期：2017-01-01 00:00:00

abstract：:CBA/CaH-kdkd mice develop hereditary tubulointerstitial disease with mononuclear cell infiltration and cyst formation, possibly representing a model of human nephronophthisis. The purpose of the present investigation was to examine the components of the fibrotic changes which typically develop in the kidneys of these ...

journal_title：Nephron

authors： Sibalic V,Sun L,Sibalic A,Oertli B,Ritthaler T,Wüthrich RP

更新日期：1998-11-01 00:00:00

abstract：:Cyclosporine (CsA) nephrotoxicity is partially mediated by renal vasoconstriction due to an imbalance between vasodilator and vasoconstrictor eicosanoids. LSL 90202 is a purified lysine salt of eicosapentaenoic acid which is a known inhibitor of renal eicosanoid synthesis. The aim of the present work was to determine ...

journal_title：Nephron

authors： Torras J,Valles J,Sanchez J,Sabate I,Seron D,Carrera M,Castelao AM,Herrero I,Puig-Parellada P,Alsina J

更新日期：1994-01-01 00:00:00

abstract：:To test the hypothesis that acute angiotensin-converting enzyme (ACE) inhibition might predict the postoperative blood pressure outcome, a single oral dose of captopril ranging from 12.5 to 100 mg, was given to 26 patients with renovascular disease and its hypotensive effect was compared with that of surgery (21 patie...

journal_title：Nephron

authors： Salvetti A,Arzilli F,Nuccorini A,Simonini N,Glorioso N,Dessì-Fulgheri P,Madeddu P,Rappelli A

更新日期：1986-01-01 00:00:00

abstract：:We conducted a retrospective study with 750 peritoneal dialysis (PD) patients in a Spanish multicenter registry between 1993 and 1999 to analyze comorbidity and mortality in type 1 diabetes (T1D), type 2 diabetes (T2D) and nondiabetic (ND) patients. 163 patients (21.7%) were diabetic--96 T1D (58.8%) and 67 T2D (42.2%)...

journal_title：Nephron

authors： Miguel A,García-Ramón R,Pérez-Contreras J,Gómez-Roldán C,Alvariño J,Escobedo J,García H,Lanuza M,López-Menchero R,Olivares J,Tornero F,Albero D,Levante PD Multicenter group.

更新日期：2002-03-01 00:00:00