Acute renal failure from inhalation of mycotoxins.

Abstract:

:Mysterious deaths of archeologists after opening Egyptian tombs have been suspected to be secondary to inhalation of mycotoxin, however, the hypothesis has never been verified. Recently, we observed a case of acute renal failure (ARF) undeniably due to inhalation of ochratoxin of Aspergillus ochraceus. After spending 8 h in a granary which had been closed for several months, a farmer and his wife suffered temporary respiratory distress; 24 h later, the woman developed nonoliguric ARF and biopsy revealed tubulonecrosis which healed in 24 days. Toxic substances were not found, but a strain of A. ochraceus producing ochratoxin was isolated from the wheat.

journal_name

Nephron

journal_title

Nephron

authors

Di Paolo N,Guarnieri A,Loi F,Sacchi G,Mangiarotti AM,Di Paolo M

doi

10.1159/000187411

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

621-5

issue

4

eissn

1660-8151

issn

2235-3186

journal_volume

64

pub_type

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