Preventive effect of ulinastatin on renal scarring in rat model of pyelonephritis induced by direct or ascending infection with Serratia marcescens or Escherichia coli.

abstract：:Severe erythrocytosis is associated with increased whole blood viscosity and impaired blood flow. Since a reduced blood flow will cause tissue hypoxia and since tissue hypoxia is associated with increased synthesis of erythropoietin, erythrocytosis per se should cause an increase in the rate of red cell production. Th...

journal_title：Nephron

authors： Erslev AJ,Caro J,Besarab A

更新日期：1985-01-01 00:00:00

abstract：:IgA nephropathy besides exhibiting a characteristic geographical distribution has been noted to have a low incidence in the blacks of the USA. There is a paucity of data on IgA nephropathy in the blacks of Africa. We report our findings among the blacks and compare these with Indians. An analysis of the primary glomer...

journal_title：Nephron

authors： Seedat YK,Nathoo BC,Parag KB,Naiker IP,Ramsaroop R

更新日期：1988-01-01 00:00:00

abstract：:A previous study from our laboratory has shown that erythropoietin (EPO), beside its traditional role in erythropoiesis, acts as an alleviator of oxidative stress and inflammation in chronic hemodialysis (HD) patients, conferred in part by activated polymorphonuclear leukocytes (PMNLs). To substantiate this phenomenon...

journal_title：Nephron

authors： Sela S,Shurtz-Swirski R,Sharon R,Manaster J,Chezar J,Shkolnik G,Shapiro G,Shasha SM,Merchav S,Kristal B

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Recently, two isoforms of cyclooxygenase (COX) have been identified, a constitutive form (COX-1) and a mitogen-inducible form (COX-2). Several studies have suggested that COX is activated in renal insufficiency, but little is known about the relationship between progression of renal insufficiency and the COX...

journal_title：Nephron

authors： Horiba N,Kumano E,Watanabe T,Shinkura H,Sugimoto T,Inoue M

更新日期：2002-05-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：:The recent experience of six large trials of antihypertensive therapy has not clearly demonstrated any beneficial effect on the prevention of coronary heart disease (CHD). The data from the HDFP study have been analyzed by three cholesterol strata at baseline. The higher the baseline cholesterol levels, the greater th...

journal_title：Nephron

authors： Schneider KA,Heyden S,Ford C

更新日期：1987-01-01 00:00:00

abstract：:The authors report on the presence of anti-HCV antibodies in a uremic chronic (UC) patient population after 6 months and 1 year with regard to certain selective preventive measures. The nonincreased number of HCV-positive subjects among the UC population could lead to the conclusion that the risk of environmental spre...

journal_title：Nephron

authors： Di Benedetto A,Bilotta E,Minale S,Tritto MC,Russo Spena S,Picardi E,Sorice P

更新日期：1992-01-01 00:00:00

abstract：:The 24-hour urinary excretion of kallikrein (K) and prostaglandin E2 (PGE2), which reflects their intrarenal synthesis, was measured in 7 normal women (NW), 10 women with essential hypertension (EH), 26 normal pregnant women (NP), 12 women with hypertension in pregnancy (HP), and 4 women with toxemia. All pregnant wom...

journal_title：Nephron

authors： Kovatz S,Arber I,Korzets Z,Rathaus M,Ben Aderet N,Bernheim J

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:There are no data available on the effects of intravenous (i.v.) methylcobalamin (Me-Cbl), the coenzymatically active form of vitamin B12 that acts as a cofactor for methionine synthase in the conversion of total homocysteine (tHcy) to methionine, with or without oral folic acid (FA) supplementation, on fast...

journal_title：Nephron

authors： Trimarchi H,Schiel A,Freixas E,Díaz M

更新日期：2002-05-01 00:00:00

abstract：:To reassess the reported protective effects of verapamil in renal ischaemia, we perfused the left kidney of uninephrectomized female Wistar rats with verapamil (0.1 and 1.0 mg/kg) immediately prior to clamping the renal artery for 60 min. When compared to controls, both doses of verapamil failed to afford protection w...

journal_title：Nephron

authors： Bock HA,Brunner FP,Torhorst J,Thiel G

更新日期：1991-01-01 00:00:00

abstract：:Radial arterial spasm in uremic patients undergoing construction of internal arteriovenous (AV) dialysis fistulas was investigated transcutaneously using ultrasonic Doppler flowmetry. In 5 of 15 patients, radial arterial blood flow was significantly decreased 5 min after anastomosing the radial cephalic vein with the ...

journal_title：Nephron

authors： Owada A,Saito H,Mochizuki T,Tanaka M,Otsuka M,Yokoyama Y,Fukuda S

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION/AIMS:The Acute Kidney Injury Network classification is based on small increases in serum creatinine (sCr) for stage 1. This study investigated whether changes in the urinary concentration of neutrophil gelatinase-associated lipocalin (uNGAL) could predict small increases in sCr in patients undergoing coron...

journal_title：Nephron

authors： Souza DF,Reis SS,Botelho RV,Ferreira-Filho SR

更新日期：2015-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a worldwide public health problem associated with a high prevalence of cardiovascular disease (CVD) and impaired quality of life. Previous research for preventing loss of glomerular filtration rate (GFR) has focused on reducing blood pressure (BP) and proteinuria. Angiotensin converting...

journal_title：Nephron

authors： Ahmed A,Jorna T,Bhandari S

更新日期：2016-01-01 00:00:00

abstract：:This report describes the case of a 50-year-old male with end-stage renal failure accompanied with congenital heart disease and polycythemia. After he had received continuous ambulatory peritoneal dialysis for 1 year, he still remained polycythemic and his serum erythropoietin titer, assayed using fetal mouse liver ce...

journal_title：Nephron

authors： Muto S,Asano Y,Hosoda S,Shionoya S,Miura Y,Urabe A,Takaku F

更新日期：1987-01-01 00:00:00

abstract：:The clinicopathological findings of isolated mesangial C3d deposition in the absence of other complement components or immunoglobulins are summarized. 55 out of 242 individual human renal biopsies examined by immunoperoxidase microscopy had isolated C3d deposition. This group consisted of 12 patients with chronic glom...

journal_title：Nephron

authors： Doi T,Kanatsu K,Suehiro F,Nagai H,Yoshida H,Hamashima Y

更新日期：1987-01-01 00:00:00

abstract：:The cytoprotective effect of ulinastatin was studied in LLC-PK1 cells treated with antimycin A, gentamicin, or cisplatin. All of the three agents induced a concentration-dependent increase in the release of lactate dehydrogenase and a decrease in the amount of remaining protein. In the cell injury models treated with ...

journal_title：Nephron

authors： Ishibashi M,Yamasaki F,Nakakuki M,Shinkawa T,Mizota M

更新日期：1997-01-01 00:00:00

abstract：:The role of T cell-mediated immunity in the early phase of nephrotoxic serum nephritis (NTN) was examined by transfer of pan T, CD8-positive, and CD4-positive cells. The disease was induced by transferring rabbit gamma-globulin (RGG)-sensitized T cells to nude (rnu/rnu) rats pretreated with a subnephritogenic dose (a ...

journal_title：Nephron

authors： Kuroda T,Kawasaki K,Oite T,Arakawa M,Shimizu F

更新日期：1994-01-01 00:00:00

abstract：:A previously described method for recovering a proximal renal tubular epitheal antigen (HRTE-1) from normal human kidney was modified by using ion-exchange and immunoaffinity chromatography in order to create easily reproducible conditions for antigen isolation. Radioiodinated HRTE-1 was then used to establish a 3-hou...

journal_title：Nephron

authors： Zager RA,Rubin NT,Ebert T,Maslov N

更新日期：1980-01-01 00:00:00

abstract：:The effects of acute beta 2-type adrenoreceptor activation with intravenous albuterol on plasma and urinary sodium, potassium, calcium, magnesium, phosphate and lithium were investigated in 9 volunteers during acute hydration. When compared with the control infusion with inactive vehicle, beta 2-type adrenoreceptor ac...

journal_title：Nephron

authors： Duss G,Bianchetti MG,Cattaneo FA,Mullis PE,Krämer R,Peheim E,Oetliker OH

更新日期：1993-01-01 00:00:00

abstract：:Diffuse crescentic glomerulonephritis was observed in a 40-year-old male patient who had a ventriculoatrial shunt implanted after a traffic accident 10 years previously. Immediately after treatment with immunosuppressants and plasma pheresis, signs of meningitis and septicemia developed. The responsible organism isola...

journal_title：Nephron

authors： Wakabayashi Y,Kobayashi Y,Shigematsu H

更新日期：1985-01-01 00:00:00

abstract：:A 5-year-old Chinese girl had had absence seizures and received sodium valproate (VPA) treatment which provided good control. Six months later, she developed interstitial nephritis with proteinuria and microhematuria. Renal biopsy revealed interstitial nephritis with granular deposition of immunoglobulin G (IgG) and C...

journal_title：Nephron

authors： Lin CY,Chiang H

更新日期：1988-01-01 00:00:00

abstract：:Cadmium-induced renal effects were followed (1989) in 16 workers previously exposed to cadmium, who had been shown 5 years earlier to have had tubular damage; all but 1 worker had persistent tubular damage (beta 2-microglobulin > 60 micrograms/mmol creatinine). The mean glomerular filtration rate (GFR) decreased from ...

journal_title：Nephron

authors： Järup L,Persson B,Edling C,Elinder CG

更新日期：1993-01-01 00:00:00

abstract：:We studied the effects of mid-term enalapril administration on protein-load-induced renal responses in 10 patients with early chronic renal failure (serum creatinine 2.70 +/- 1.0 mg/dl). The oral protein load was performed twice, before and after a 10-day therapy with enalapril. Glomerular filtration rate (125I-iothal...

journal_title：Nephron

authors： Oldrizzi L,Rugiu C,Maschio G

更新日期：1989-01-01 00:00:00

abstract：:The effect of treatment with 1 alpha-hydroxycholecalciferol (1 alpha-OH-D3) and different diets on uremic arterial disease was studied. Three groups of rabbits with chronic renal failure (CRF) were kept on three diets with a low, medium or high content of calcium and phosphate. Half the rabbits in each group were trea...

journal_title：Nephron

authors： Tvedegaard E,Ladefoged O,Nielsen M,Kamstrup O

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Cyst infection is one of the complications of autosomal dominant polycystic kidney disease and polycystic liver disease. The diagnosis is typically made on a mix of clinical, laboratory and imaging abnormalities but the importance of individual items is uncertain. We aimed to perform a Delphi survey amongst ...

journal_title：Nephron

authors： Lantinga MA,Darding AJ,de Sévaux RG,Alam A,Bleeker-Rovers CP,Bobot M,Cornec-Le Gall E,Gevers TJ,Hassoun Z,Meijer E,Mrug M,Nevens F,Onuchic LF,Pei Y,Piccoli GB,Pirson Y,Rangan GK,Torra R,Visser FW,Jouret F,Kanaan N

更新日期：2016-01-01 00:00:00

abstract：:Conglomerates of food and mucus or phytobezoars composed of vegetable matter are sometimes found in the stomach in the general population. Reports of phytobezoars in uremic patients are, however, scarce. Here we describe 2 uremic patients in which esophagogastroduodenoscopy was performed due to dyspepsia associated wi...

journal_title：Nephron

authors： Catalano C,Leone L,Fabbian F,Conz PA

更新日期：2002-03-01 00:00:00

abstract：:During hemodialysis, platelets are activated across a dialyzer. Soluble P-selectin (sP-selectin) is a form of P-selectin which is a glycoprotein relocated from secretory granules to the surfaces of platelets and endothelial cells after these cells have been physiologically activated. To investigate whether sP-selectin...

journal_title：Nephron

authors： Kawabata K,Nagake Y,Shikata K,Fukuda S,Nakazono H,Takahashi M,Ichikawa H,Makino H

更新日期：1998-01-01 00:00:00

abstract：:Micropuncture studies were performed in intact and thyroparathyroidectomized (TPTX) dogs to evaluate the relationship between the absolute level of serum ultrafilterable phosphate concentration (SUFP) and proximal bicarbonate reabsorption. In both groups of animals, a reverse linear relationship was noted between the ...

journal_title：Nephron

authors： Puschett JB,Fernandez PC

更新日期：1977-01-01 00:00:00

abstract：:Renal handling of urate, xanthine and hypoxanthine was studied in a hypouricemic patient who had increased plasma concentrations of xanthine and hypoxanthine. The patient, a 50-year-old man, had been suffering from Parkinson's disease, while neither systemic disorders nor particular renal diseases known to affect plas...

journal_title：Nephron

authors： Kawachi M,Kono N,Kiyokawa H,Mineo I,Nakajima H,Shimizu T,Yorifuji S,Kuwajima M,Tarui S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:In the last decade, great advances have been made in the field of membranous nephropathy (MN). The autoimmune nature of the disease has been confirmed with the description of diverse antigens, and few but very important prospective trials regarding treatment alternatives have been published, changing profoun...

journal_title：Nephron

authors： Trujillo H,Alonso M,Praga M

更新日期：2020-01-01 00:00:00