Effect of 1 alpha-hydroxyvitamin D3 and dietary calcium and phosphate on the aortic mineral content in rabbits with mild azotemia.

abstract：:Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...

journal_title：Nephron

authors： Hsu CH,Kurtz TW

更新日期：1981-01-01 00:00:00

abstract：:To clarify the reliability of urinary trehalase activity as a marker of cellular proliferation and/or damage of renal proximal tubules, the activity was examined in healthy newborn infants or infants treated with tobramycin, a drug known as causing tubular cell damage. Eighty-one newborn infants (56 mature infants and...

journal_title：Nephron

authors： Sasai-Takedatsu M,Kojima T,Taketani S,Ono A,Kitamura N,Kobayashi Y

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND/AIMS:Glomerular basement membrane (GBM) thickening and mesangial matrix expansion are characteristic features of diabetic nephropathy. The present study investigates the role of endothelins (ETs) in the pathogenesis of such changes in diabetic nephropathy. METHODS:Diabetic (streptozotocin-induced, 65 mg/kg)...

journal_title：Nephron

authors： Chen S,Evans T,Deng D,Cukiernik M,Chakrabarti S

更新日期：2002-01-01 00:00:00

abstract：:Glomerulonephritis as well as kidney injury secondary to fulminant intravascular hemolysis are rare extrapulmonary manifestations of Mycoplasma pneumoniae infection. We describe a 50-year-old female diagnosed with M. pneumoniae infection-associated hemolytic anemia, characterized by negative cold agglutinin tests but ...

journal_title：Nephron

authors： Carrara C,Abbate M,Sabadini E,Remuzzi G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Progressive nephropathy is one of the main features of Fabry disease (FD). It has been supposed that an early phase, clinically silent disease occurs in childhood and adolescence and is characterized by glomerular hyperfiltration (HF). Surprisingly, although HF has been reported in several stu...

journal_title：Nephron

authors： Riccio E,Sabbatini M,Bruzzese D,Annicchiarico Petruzzelli L,Pellegrino A,Spinelli L,Esposito R,Imbriaco M,Feriozzi S,Pisani A,on behalf of AFFIINITY Group.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIM:Interleukin (IL)-17 is a newly discovered cytokine that is secreted by activated memory CD4+ T cells and modulated the early stage of immune response. To elucidate the pathophysiology of minimal-change nephrotic syndrome (MCNS), we focused on IL-17, which is one of the key factors in regulating an inflam...

journal_title：Nephron

authors： Matsumoto K,Kanmatsuse K

更新日期：2002-06-01 00:00:00

abstract：:329 patients were evaluated from 1978 to 1990. 40 new cases of non-A non-B hepatitis were observed, all regarding patients on hemodialysis. Since the beginning of 1989, we introduced measures to limit the diffusion of the virus: reduction to a minimum of blood transfusions and a new disinfection protocol for monitors,...

journal_title：Nephron

authors： La Russa A,Bufano G,Cauzzi L,Pecchini P

更新日期：1992-01-01 00:00:00

abstract：:The feasibility of room temperature incubation of Microstix-3 specimens to detect urinary tract infection was studied. This procedure, if successful, would allow home monitoring of patients and eliminate the need for an incubator. Four Microstix-3 strips were dipped into each of 1,241 urine specimens and incubated at ...

journal_title：Nephron

authors： Akriotis VJ,Arbus GS

更新日期：1982-01-01 00:00:00

abstract：:The methylenetetrahydrofolate reductase (MTHFR) gene polymorphism has been shown to be associated with cardiovascular disease in healthy subjects as well as in patients with end-stage renal disease (ESRD). In this study, we examined the allelic frequency and genotype distribution of the MTHFR gene in 151 Chinese ESRD ...

journal_title：Nephron

authors： Lim PS,Hung WR,Wei YH

更新日期：2001-03-01 00:00:00

abstract：:Human peritoneal mesothelial cells lie on a basement membrane-like material consisting of fibronectin (FN), type I collagen (CI), type III collagen (CIII) and laminin (LA). To understand how these extracellular matrix (ECM) proteins affect mesothelial cell behavior, we investigated their effect on the adhesion and pro...

journal_title：Nephron

authors： Yen CJ,Fang CC,Chen YM,Lin RH,Wu KD,Lee PH,Tsai TJ

更新日期：1997-01-01 00:00:00

abstract：:We examined the ultrastructure of the bovine glomerular basement membrane (GBM) and tubular basement membrane (TBM) using ultra-high-resolution scanning electron microscopy after conductive staining without metal coating. Purified basement membranes (BMs) were obtained by sonication and acellular BMs by detergent trea...

journal_title：Nephron

authors： Yamasaki Y,Makino H,Ota Z

更新日期：1994-01-01 00:00:00

abstract：:To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

journal_title：Nephron

authors： Duan SB,Wu HW,Luo JA,Liu FY

更新日期：1999-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:Changes in renal function and structure are frequently observed in patients with diabetes mellitus. In the early phases of the disease, alterations in glomerular filtration rate, renal plasma flow, glomerular permeability and tubular capacity for glucose reabsorption occur. In the late stages of juvenile onset diabete...

journal_title：Nephron

authors： Rubenstein AH,Mako ME,Horwitz DL

更新日期：1975-01-01 00:00:00

abstract：:Anderson-Fabry disease (AFd) is a rare X-linked disorder characterized by deficiency of alpha-galactosidase A that leads to systemic accumulation of neutral glycosphingolipids, predominantly globotriaosylceramide (Gb3), in body fluids and visceral tissues, including the kidney. End-stage renal failure is a common mani...

journal_title：Nephron

authors： Sessa A,Meroni M,Battini G,Maglio A,Nebuloni M,Tosoni A,Panichi V,Bertagnolio B

更新日期：2002-06-01 00:00:00

abstract：:Prolongation of repolarization dispersion (QT interval dispersion) measured from the 12-lead surface ECG has been associated with sudden cardiac death and ventricular tachyarrhythmias in a variety of cardiac disorders. The aim of our study was to assess the effects of hemodialysis (HD) and continuous ambulatory perito...

journal_title：Nephron

authors： Kantarci G,Ozener C,Tokay S,Bihorac A,Akoğlu E

更新日期：2002-08-01 00:00:00

abstract：:Cardiovascular complications seriously affect posttransplant survival in patients after successful renal transplantation. Abnormalities in blood rheology may contribute to these complications. Therefore, we studied the blood rheology before and during a 1-year observation period after grafting in 9 patients by serial ...

journal_title：Nephron

authors： Koppensteiner R,Derfler K,Ehringer H

更新日期：1996-01-01 00:00:00

abstract：:Mean renal blood flow (MRBF), cortical blood flow (CBF), glomerular filtration rate (GFR), heart rate, arterial blood pressure, Na+ and K+ excretion were determined before and 10 min after intrarenal administration of dihydroergocristine (0.017 mg/kg b.w.) in 13 patients suffering from liver cirrhosis. Cardiac output ...

journal_title：Nephron

authors： Gatta A,Merkel C,Grassetto M,Milani L,Zuin R,Ruol A

更新日期：1982-01-01 00:00:00

abstract：:Effect of the immunosuppressive agent, ciclosporin (CS), on bovine serum albumin (BSA) nephritis in rats was evaluated. Eight weeks after immunization, 19 male Wistar rats received a daily intravenous dose of BSA (2 mg). Two weeks later, 11 rats received BSA and an oral dose of CS (10 mg/kg), and 8 rats received only ...

journal_title：Nephron

authors： Fujita M,Iida H,Asaka M,Izumino K,Takata M,Sasayama S

更新日期：1991-01-01 00:00:00

abstract：:Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission ...

journal_title：Nephron

authors： Nair RB,Date A,Kirubakaran MG,Shastry JC

更新日期：1987-01-01 00:00:00

abstract：:A modified sieving technique has been developed to isolate pure glomeruli from monkey, sheep, dog, rabbit and rat kidney. Glomeruli from all these species have been grown in tissue culture and the glomerular cell outgrowth studied by light microscopy and time-lapse cinemicroscopy. The pattern of growth was the same fo...

journal_title：Nephron

authors： Holdsworth SR,Glasgow EF,Atkins RC,Thomson NM

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of treatment for renal anemia in patients with chronic kidney disease (CKD). This meta-analysis was designed to evaluate their efficacy and safety. METHOD:Eight databases were searched for randomized controlled trials (RCTs). ...

journal_title：Nephron

authors： Wen T,Zhang X,Wang Z,Zhou R

更新日期：2020-01-01 00:00:00

abstract：:Fifteen patients with advanced renal failure (creatinine clearance less than 25 ml/mn) and with severe albuminuria (greater than 1.5 g/24 h) were put on a low-protein (0.3 g/kg body weight), low-phosphorus (5-7 mg/kg body weight) diet supplemented with essential amino acids and ketoanalogues. During the 6-month follow...

journal_title：Nephron

authors： Aparicio M,Bouchet JL,Gin H,Potaux L,Morel D,de Precigout V,Lifermann F,Gonzalez R

更新日期：1988-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination. ...

journal_title：Nephron

authors： Melappioni M,Baldassari M,Baldini S,Radicioni R,Panichi N

更新日期：1992-01-01 00:00:00

abstract：:Plasma and urine beta-2-microglobulin (B2m) were measured in 37 renal transplant recipients and 34 healthy subjects. Serum B2m was found to be a more sensitive index of renal function than serum creatinine. Renal transplant recipients had significantly higher urine B2m when compared with normal controls. Normal subjec...

journal_title：Nephron

authors： Woo KT,Lee EJ,Lau YK,Lim CH

更新日期：1985-01-01 00:00:00

abstract：:A 37-year-old female presented with acute onset of glomerulonephritis 10 days following an upper respiratory infection. Serum complement components were depressed and proteinuria exceeded 3.0 g daily. Renal biopsy revealed granular staining of IgG and C3 along the basement membrane as well as small amounts of IgA in a...

journal_title：Nephron

authors： Yoshizawa N,McClung JA,Ohshima S,Takahashi K,Treser G

更新日期：1986-01-01 00:00:00

abstract：:An 11-year-old boy developed Kaposi's sarcoma and progressive T lymphocyte deficiency 5 years after cadaveric kidney transplantation for end-stage renal disease. He had received 17 individual red blood cell transfusions prior to and during transplantation in 1980. Human immunodeficiency virus (HIV) was cultured from b...

journal_title：Nephron

authors： Malekzadeh MH,Church JA,Siegel SE,Mitchell WG,Opas L,Lieberman E

更新日期：1987-01-01 00:00:00

abstract：:The effects of a high-protein (HP) and low-protein (LP) meal on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and renal vascular resistance (RVR) were examined in conscious dogs. Ingestion of the HP and LP meal produced a temporary increase in systemic hemodynamic parameters due in part to a 'c...

journal_title：Nephron

authors： Zawada ET,Saelens DA,Alavi FK,Lembke JM

更新日期：1994-01-01 00:00:00