Meshwork structures in bovine glomerular and tubular basement membrane as revealed by ultra-high-resolution scanning electron microscopy.

abstract：:A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibo...

journal_title：Nephron

authors： Mizuiri S,Hasegawa A,Kikuchi A,Amagasaki Y,Nakamura N,Sakaguchi H

更新日期：1993-01-01 00:00:00

abstract：:We have evaluated the effect of the antihyperlipidemic agent probucol on hyperlipidemia in patients with nephrotic syndrome. Twelve patients with long-standing nephrotic syndrome received 500 mg of probucol daily for 12 weeks. Serum total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol were significantl...

journal_title：Nephron

authors： Iida H,Izumino K,Asaka M,Fujita M,Nishino A,Sasayama S

更新日期：1987-01-01 00:00:00

abstract：:While the bulk of renal hypertrophy induced by contralateral nephrectomy or a high-protein diet consists of tubular cell growth, there is some evidence suggesting that mesangial cells play a role in this phenomenon. Previous data suggest that this role of mesangial cells is associated with their proliferation. We, the...

journal_title：Nephron

authors： Weissgarten J,Modai D,Berman S,Cohn M,Galperin E,Averbukh Z

更新日期：2000-07-01 00:00:00

abstract：:Mizoribine has been shown to possess an immunosuppressive action that inhibits the proliferation of lymphocytes selectively by interfering with inosine monophosphate dehydrogenase. Recent studies have demonstrated that mizoribine improves renal tubulointerstitial fibrosis in the rat model of unilateral ureteral obstru...

journal_title：Nephron

authors： Sato N,Shiraiwa K,Kai K,Watanabe A,Ogawa S,Kobayashi Y,Yamagishi-Imai H,Utsunomiya Y,Mitarai T

更新日期：2001-10-01 00:00:00

abstract：:Medullary sponge kidney was found in association with congenital absence of teeth (anodontia) in 3 siblings of a single family. Anodontia occurs in the rare familial syndrome of ectodermal dysplasia, but its association with a renal (mesodermal) anomaly is not known. The present report lends further support to a possi...

journal_title：Nephron

authors： Khoury Z,Brezis M,Mogle P

更新日期：1988-01-01 00:00:00

abstract：:The effect of imidazole-2-hydroxibenzoate on urinary excretion rates of glycosaminoglycans and albumin in 22 insulin-dependent diabetics with albumin excretion rates under 300 mg/day was evaluated in a 165-day double blind crossover study. Unlike placebo, the drug reduced glycosaminoglycan and albumin excretion rates ...

journal_title：Nephron

authors： Baggio B,Briani G,Cicerello E,Gambaro G,Giorato C,Iori E,Lavagnini T,Crepaldi G

更新日期：1988-01-01 00:00:00

abstract：:The clinical profile of a patient with a 15 years' evolution of acne conglobata developing systemic amyloidosis with severe renal involvement is described, and the possible influence of suppurative skin foci surgical excision on the rapid progression to terminal renal failure is discussed. This etiological cause of se...

journal_title：Nephron

authors： Naya MT,Soria C,Quereda C,Orte L,Romero R,Ortuño J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Idiopathic membranous nephropathy remains the leading cause of nephrotic syndrome in Caucasian adults. Immunosuppressive therapy with cyclosporine (CSA) is often successful in reducing proteinuria, but its use is associated with a high relapse rate. Rituximab, a monoclonal antibody that specifically targets ...

journal_title：Nephron

authors： Fervenza FC,Canetta PA,Barbour SJ,Lafayette RA,Rovin BH,Aslam N,Hladunewich MA,Irazabal MV,Sethi S,Gipson DS,Reich HN,Brenchley P,Kretzler M,Radhakrishnan J,Hebert LA,Gipson PE,Thomas LF,McCarthy ET,Appel GB,Jeffers

更新日期：2015-01-01 00:00:00

abstract：:Post-transplant cure tubular necrosis (ATN) represents the most frequent cause of delayed graft function in the immediate post-transplant period. Several causes have been associated with the development of post-transplant ATN such as donor and recipient ages, cold-warm ischemia times, HLA mismatches, and postoperative...

journal_title：Nephron

authors： Torregrosa JV,Campistol JM,Fenollosa B,Montesinos M,Romar A,Martinez de Osaba MJ

更新日期：1996-01-01 00:00:00

abstract：:5 patients, including 4 with partial lipodystrophy and 1 with dense deposit disease (type II mesangiocapillary glomerulonephritis; MCGN), had positive C3 nephritic factor assays by both a crossed-gel immunoelectrophoretic and a magnesium-dependent hemolytic assay. One or more early classic complement component was sig...

journal_title：Nephron

authors： McLean RH,Siegel NJ,Kashgarian M

更新日期：1980-01-01 00:00:00

abstract：:Pruritus is a common symptom among patients undergoing long-term hemodialysis. However, its etiology remains unclear. In an attempt to clarify its cause we tried to correlate pruritus and its intensity with several serological variables in 94 hemodialysis patients. Our results show that higher serum aluminum concentra...

journal_title：Nephron

authors： Friga V,Linos A,Linos DA

更新日期：1997-01-01 00:00:00

abstract：:Renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (RBF), glomerular filtration rate (GFR), sodium excretion (UNaV), and intrarenal distribution of blood ...

journal_title：Nephron

authors： Katz MA,Shear L

更新日期：1975-01-01 00:00:00

abstract：:Animal models are essential tools to understand the mechanisms underlying the development and progression of renal disease and to study potential therapeutic approaches. Recently, interventional models suitable to induce acute and chronic kidney disease in the mouse have become a focus of interest due to the wide avai...

journal_title：Nephron

authors： Rabe M,Schaefer F

更新日期：2016-01-01 00:00:00

abstract：:It is unknown whether continuous renal replacement techniques result in diminished morbidity and mortality when compared to conventional dialytic techniques. To investigate this issue a previously described, retrospectively studied group of critically ill patients with severe acute renal failure treated by conventiona...

journal_title：Nephron

authors： Bellomo R,Farmer M,Parkin G,Wright C,Boyce N

更新日期：1995-01-01 00:00:00

abstract：:Interleukin-1 receptor antagonist (IL-1Ra) is a specific inhibitor of interleukin-1 (IL-1). It is structurally similar to IL-1 and binds to IL-1 cell surface receptors, but does not transduce a signal. To examine the relationship between the production of IL-1Ra and IL-1, we incubated peripheral blood mononuclear cell...

journal_title：Nephron

authors： Pereira BJ,King AJ,Falagas ME,Dinarello CA

更新日期：1994-01-01 00:00:00

abstract：:We report two cases of patients with analgesic nephropathy presenting with the symptoms of hypercalcaemia, and who were found to have transitional cell carcinomas of the renal pelvis. On removal of the tumours, calcium levels fell to normal, indicating that a humoral factor produced by the tumour caused the hypercalca...

journal_title：Nephron

authors： Derbyshire ND,Asscher AW,Matthews PN

更新日期：1989-01-01 00:00:00

abstract：:Creatinine clearance has been repeatedly measured in three groups of chronic uremics. In the first control group (31 cases), following a conventional low-protein diet, creatinine clearance declined linearly with time. In the second group (12 cases), following very low nitrogen diet supplemented with essential amino ac...

journal_title：Nephron

authors： Barsotti G,Guiducci A,Ciardella F,Giovannetti S

更新日期：1981-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection has been associated with several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) were also described in several patients with overt AIDS. We describe a patient who presented with HUS and only subsequent investigation to find the caus...

journal_title：Nephron

authors： Badesha PS,Saklayen MG

更新日期：1996-01-01 00:00:00

abstract：:A critical survey of the literature suggests that elevated serum uric acid is definitely associated with hypertension and may function as an independent risk factor in the development of this disease. The possible role of an elevated serum uric acid as an independent risk factor for the development of ischemic heart d...

journal_title：Nephron

authors： Tweeddale MG,Fodor JG

更新日期：1979-01-01 00:00:00

abstract：:329 patients were evaluated from 1978 to 1990. 40 new cases of non-A non-B hepatitis were observed, all regarding patients on hemodialysis. Since the beginning of 1989, we introduced measures to limit the diffusion of the virus: reduction to a minimum of blood transfusions and a new disinfection protocol for monitors,...

journal_title：Nephron

authors： La Russa A,Bufano G,Cauzzi L,Pecchini P

更新日期：1992-01-01 00:00:00

abstract：:Acute renal failure due to tubulo-interstitial nephritis developed in a 15-year-old girl. The disease was accompanied by uveitis and an inflammatory syndrome, consisting of a markedly increased erythrocyte sedimentation rate and high serum gamma globulin levels. The nephropathy as well as the inflammatory syndrome sub...

journal_title：Nephron

authors： Vanhaesebrouck P,Carton D,De Bel C,Praet M,Proesmans W

更新日期：1985-01-01 00:00:00

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:In February 2017, our laboratory implemented an electronic AKI flagging system for primary care using the NHS England AKI detection algorithm. Our study investigated the impact on patient follow-up, hospital admission, length of stay, and mortality. METHODS:Primary care results March 2017-February 2018...

journal_title：Nephron

authors： Barton AL,Williams SBM,Dickinson SJ,Parry RG,Pollard A

更新日期：2020-01-01 00:00:00

abstract：:A 5-year-old Japanese boy showed nephritis similar to, but distinct from, that in Alport syndrome. Nephrotic syndrome without hematuria was noticed at age 2, although renal biopsy at age 4 revealed widespread irregular thickening of the glomerular basement membrane with splitting of the lamina densa on electron micros...

journal_title：Nephron

authors： Kawakami H,Murakami T,Murano I,Ushijima T,Taguchi T,Hattori S,Kajii T

更新日期：1990-01-01 00:00:00

abstract：:The purpose of this study was to identify and characterize humic compounds in Anticolana Valley (Fiuggi) water. The capacity of this class of compounds to mobilize metals from solid phases could have an important role in calculi solubilization. Humic compounds were isolated, purified and characterised by FTIR, 1H-NMR ...

journal_title：Nephron

authors： Calace N,D'Ascenzo G,De Angelis Curtis S,Delfini M,Fraioli A,Petronio BM

更新日期：1999-01-01 00:00:00

abstract：:Cardiovascular disease remains the major cause of mortality in hemodialysis patients. Abnormal oxidative stress and impaired antioxidant defense may contribute to accelerated atherogenesis associated with uremia. As oxidative modification of lipids appears to be a prerequisite for the development of atherosclerotic le...

journal_title：Nephron

authors： Lim PS,Chan EC,Lu TC,Yu YL,Kuo SY,Wang TH,Wei YH

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...

journal_title：Nephron

authors： Shaw C,Steenkamp R,Davenport A

更新日期：2015-01-01 00:00:00

abstract：:Conjugated diene fatty acids (CDFA) were evaluated by second derivative spectrophotometry in the plasma and adipose tissue of 42 chronic renal failure (CFR) patients in conservative treatment, 40 patients treated by hemodialysis (HD) with cuprophane, cellulose acetate or hemophan, 29 treated by hemodiafiltration (HDF)...

journal_title：Nephron

authors： Lucchi L,Banni S,Botti B,Cappelli G,Medici G,Melis MP,Tomasi A,Vannini V,Lusvarghi E

更新日期：1993-01-01 00:00:00

abstract：:Deproteinized plasma from patients with renal failure had an inhibitory effect on Na,K ATPase activity measured in vitro by a linked-enzyme assay. No inhibitory effect was observed with plasma from normal subjects or from patients undergoing chronic ambulatory peritoneal dialysis. The inhibition of Na,K ATPase whether...

journal_title：Nephron

authors： Stokes GS,Norris LA,Marwood JF,Johnston H,Caterson RJ

更新日期：1990-01-01 00:00:00