Activation of the classic complement pathway in patients with the C3 nephritic factor.

abstract：:We report a patient with compensated congestive heart failure who developed acute anuric renal failure immediately after indomethacin and triamterene had been added to the treatment regimen. Renal function failed to improve promptly with discontinuation of these medications, anuria persisting for 11 days. While it is ...

journal_title：Nephron

authors： Weinberg MS,Quigg RJ,Salant DJ,Bernard DB

更新日期：1985-01-01 00:00:00

abstract：:A few cases of nephrotic syndrome with the glomerular deposition of an amyloid-like material which did not stain with Congo red have been documented. But extrarenal deposits have not been previously reported in this disease. We describe here a case of nephrotic syndrome associated with the deposition of an amyloid-lik...

journal_title：Nephron

authors： Ozawa K,Yamabe H,Fukushi K,Osawa H,Chiba N,Miyata M,Seino S,Inuma H,Sasaki T,Yoshikawa S

更新日期：1991-01-01 00:00:00

abstract：:Pruritus is a common symptom among patients undergoing long-term hemodialysis. However, its etiology remains unclear. In an attempt to clarify its cause we tried to correlate pruritus and its intensity with several serological variables in 94 hemodialysis patients. Our results show that higher serum aluminum concentra...

journal_title：Nephron

authors： Friga V,Linos A,Linos DA

更新日期：1997-01-01 00:00:00

abstract：:Hemodynamic and hormonal actions of acute (50 mg) and chronic (150 mg/day) captopril were tested in 10 patients with essential hypertension. Under short-term conditions blood pressure was reduced, heart rate and plasma adrenaline did not change, plasma angiotensin II and plasma aldosterone decreased. Plasma renin acti...

journal_title：Nephron

authors： Stanek B,Silberbauer K

更新日期：1986-01-01 00:00:00

abstract：:The relationship between glycosaminoglycans and beta 2-microglobulin, glycosaminoglycans and N-acetyl-beta-D-glucosaminidase as well as the relationship between the chondroitin sulfate/heparan sulfate ratio and SDS electrophoresis in the urine of subjects from the endemic area of Balkan nephropathy was studied in orde...

journal_title：Nephron

authors： Juretić D,Cvoriscec D,Vuković-Holjevac A,Benković J,Lipovac K,Stavljenić A

更新日期：1993-01-01 00:00:00

abstract：:The feasibility of room temperature incubation of Microstix-3 specimens to detect urinary tract infection was studied. This procedure, if successful, would allow home monitoring of patients and eliminate the need for an incubator. Four Microstix-3 strips were dipped into each of 1,241 urine specimens and incubated at ...

journal_title：Nephron

authors： Akriotis VJ,Arbus GS

更新日期：1982-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：:Nonspecific symptoms are common in dialysis patients but few methods are available to measure their severity and their response to alteration in dialysis therapy. To determine the clinical features and measure the severity of the most important symptoms in end-stage renal disease (ESRD) patients, 97 dialysis patients ...

journal_title：Nephron

authors： Parfrey PS,Vavasour HM,Henry S,Bullock M,Gault MH

更新日期：1988-01-01 00:00:00

abstract：:A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism, presenting severe hyponatremia, is described. A 57-year-old man complaining of nausea, vomiting and fatigability was admitted to our hospital because of hyponatremia (114 mEq/I). The low levels of serum cortisol and urinary 17-OHCS suggested gluc...

journal_title：Nephron

authors： Okada K,Takahashi S

更新日期：1996-01-01 00:00:00

abstract：:The assessment of the hypothalamic-pituitary-adrenal axis in patients with chronic renal failure (CRF) on hemodialysis is often hampered by abnormal responses to the standard 1-mg dexamethasone suppression test. Various mechanisms have been proposed to explain this lack of suppressibility. The present study was design...

journal_title：Nephron

authors： Van Herle AJ,Birnbaum JA,Slomowitz LA,Mayes D,Chandler DW,Rosenblit PD,Nissenson A

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND/AIMS:Genetic cell ablation using the human diphtheria toxin receptor (hDTR) is a new strategy used for analysing cellular function. Diphtheria toxin (DT) is a cytotoxic protein that leaves mouse cells relatively unaffected, but upon binding to hDTR it ultimately leads to cell death. We used a podocyte-specif...

journal_title：Nephron

authors： Stevens M,Neal CR,Salmon AHJ,Bates DO,Harper SJ,Oltean S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Complement factor H (hCFH) plays a key inhibitory role in the control of the alternative complement pathway. We examined whether urinary hCFH (U-hCFH) levels is useful as an indirect indicator of renal damage. METHODS:Urine samples were obtained from 104 patients with renal disease. Urine was collected with...

journal_title：Nephron

authors： Tamano M,Fuke Y,Endo M,Ohsawa I,Fujita T,Ohi H

更新日期：2002-01-01 00:00:00

abstract：:Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...

journal_title：Nephron

authors： Lobo PI,Okusa MD

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Renal function deteriorates with age, but a few studies have addressed this longitudinally in elderly women. Our objective was, using 5 estimated glomerular filtration rates (eGFR)-equations, to evaluate changes in renal function and association with adverse outcomes for a decade in 75-year-old women. ...

journal_title：Nephron

authors： Malmgren L,McGuigan FE,Berglundh S,Westman K,Christensson A,Åkesson K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:A constant finding in beta (2)-microglobulin (beta 2m) amyloidosis is an increase in tissue heparan sulfate (HS) and chondroitin sulfate (CS) proteoglycans (PGs) at sites of amyloid deposits. However, the binding characteristics of PGs with beta 2m have not been elucidated yet. METHODS:Using affinity retard...

journal_title：Nephron

authors： Ohashi K,Kisilevsky R,Yanagishita M

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Haemophilus influenzae infection is a mild and self-limited disease in the healthy population. However, it may show an aggressive course in the immunocompromised state which underlines the importance of vaccination against this agent. On the other hand, posttranplant immunosuppression may impair immune respo...

journal_title：Nephron

authors： Sever MS,Yildiz A,Eraksoy H,Badur S,Yüksel-Onel D,Görçin B,Türk S,Erkoç R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIM:Acute renal failure (ARF) is one of the common problems associated with sepsis or multiple organ dysfunction syndrome (MODS). We have investigated the effects of inhibiting selectin-mediated cell adhesion on lipopolysaccharide-induced ARF in rabbits, using sialyl Lewis X oligosaccharide and PB1.3, an ant...

journal_title：Nephron

authors： Hayashi H,Imanishi N,Ohnishi M,Tojo SJ

更新日期：2001-04-01 00:00:00

abstract：:Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...

journal_title：Nephron

authors： Ishikawa I

更新日期：1991-01-01 00:00:00

abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha) and its soluble TNF receptors 55 and 75 (sTNFR55, sTNFR75), interleukin-1 beta (IL-1BETA) and interleukin-6 (IL-6) were measured in plasma from 13 patients with the hemolytic uremic syndrome (HUS) on admission. No significant changes in the plasma levels of TNF-alp...

journal_title：Nephron

authors： van de Kar NC,Sauerwein RW,Demacker PN,Grau GE,van Hinsbergh VW,Monnens LA

更新日期：1995-01-01 00:00:00

abstract：:HCV is seen as an emergent problem in Dialysis Units; in fact, the patients of these centers are at high risk for blood-transmitted infections, through coming microepidemies. For this reason and using the same method, we have studied the prevalence of anti-HCV and virus-derived hepatitis in a dialytic population of 10...

journal_title：Nephron

authors： Scotto G,Savastano AM,Forcella M,Tantimonaco G,Amato G,Salatino G,Pappani A,Stella I

更新日期：1992-01-01 00:00:00

abstract：:To eliminate the discomfort caused by surgical methods and the risks involved using the trocar, for 1 year we have been using a new technique for insertion of peritoneal catheters (PC). We devised a steel instrument, vaguely resembling a rhinoscope, composed of two semicones. The handles are connected by a screw to pe...

journal_title：Nephron

authors： Di Paolo N,Manganelli A,Strappaveccia F,De Mia M,Gaggiotti E

更新日期：1985-01-01 00:00:00

abstract：:End-stage renal disease (ESRD) is common, costly, and it results from progressive chronic kidney disease (CKD). ESRD claims many lives every year. It is increasingly recognized that episodes of acute kidney injury (AKI) predispose to the future development of CKD and ESRD. While our understanding of the pathophysiolog...

journal_title：Nephron

authors： Ó hAinmhire E,Humphreys BD

更新日期：2017-01-01 00:00:00

abstract：:Increased plasma and red blood cell concentrations of riboflavin have been reported in uremia. The possible role of altered intestinal absorption of riboflavin in the genesis of this abnormality is not known. For this reason we examined the intestinal absorption of riboflavin in rats made uremic by subtotal nephrectom...

journal_title：Nephron

authors： Vaziri ND,Said HM,Hollander D,Barbari A,Patel N,Dang D,Kariger R

更新日期：1985-01-01 00:00:00

abstract：:Most hypertensive subjects are overweight, and as a consequence have an increased prevalence of hypercholesterolaemia, impaired glucose tolerance, and left ventricular hypertrophy. Reduction of the blood pressure by antihypertensive drugs without control of the obesity leaves these additional risk factors for cardiova...

journal_title：Nephron

authors： Ramsay LE

更新日期：1987-01-01 00:00:00

abstract：:The incidence of acute tubular necrosis (need for hemodialysis immediately after transplantation) and its severity (the number of days dialysis was needed) were studied in 299 patients who were randomized prior to transplantation into undergoing splenectomy or not having splenectomy. There was no difference in the inc...

journal_title：Nephron

authors： Pru CE,Fryd DS,Kjellstrand CM

更新日期：1984-01-01 00:00:00

abstract：:A 55-year-old white male, with silicosis diagnosed 10 years earlier, presented massive proteinuria with microscopic hematuria, moderate renal failure and distal polyneuropathy. Bilateral renal angiography showed multiple intraparenchymal saccular aneurysms. Renal biopsy disclosed a focal segmental necrotizing glomerul...

journal_title：Nephron

authors： Arnalich F,Lahoz C,Picazo ML,Monereo A,Arribas JR,Martínez Ara J,Vázquez JJ

更新日期：1989-01-01 00:00:00

abstract：:The concentration changes, during hemodialysis treatment, of 18 characteristic uremia compounds, analyzed by high-pressure liquid chromatography in sera of renal patients were studied. Pre- to postdialysis concentration ratios (dialysis ratio, D) varied from 0.83 to 3.04 for the different solutes. A division into thre...

journal_title：Nephron

authors： Schoots AC,Peeters JA,Gerlag PG

更新日期：1989-01-01 00:00:00

abstract：:Chromoblastomycosis is a rare, deep mycosis seen mostly in tropical and subtropical regions. We have encountered a kidney transplant recipient with this subcutaneous mycosis developing as an asymptomatic mass in the right forearm. The lesion recurred after an initial local excision, but it is now apparently cured 10 m...

journal_title：Nephron

authors： Morales LA,González ZA,Santiago-Delpín EA

更新日期：1985-01-01 00:00:00

abstract：:We report a case of visceral leishmaniasis in a 38-year-old renal transplant recipient living in an endemic country. Antimonial derivatives induced a rapid remission. A review of the literature disclosed 8 cases of this association with a fatal fulminant outcome in 5 cases. We suggest that the specific immunosuppressi...

journal_title：Nephron

authors： Moulin B,Ollier J,Bouchouareb D,Purgus R,Olmer M

更新日期：1992-01-01 00:00:00

abstract：:The mitochondrial DNA mutation mt.3243A>G is most commonly associated with maternally inherited diabetes and deafness (MIM 52,000), but it has protean phenotypes including renal disease due to focal segmental glomerulosclerosis. We describe monozygotic twins who both harboured this mutation and developed ESRD. Althoug...

journal_title：Nephron

authors： Shand JAD,Potter HC,Pilmore HL,Cundy T,Murphy R

更新日期：2020-01-01 00:00:00