Affinity binding of glycosaminoglycans with beta(2)-microglobulin.

abstract：BACKGROUND:A high prevalence of cardiovascular diseases (CVDs) and infections in patients with chronic kidney disease (CKD) arises partly due to a high inflammatory state and aberrations in immune cells function. Following in vitro stimulation of leukocytes with different T-cell mitogens, we observed a lower level of i...

journal_title：Nephron

authors： Mansouri L,Nopp A,Jacobson SH,Hylander B,Lundahl J

更新日期：2017-01-01 00:00:00

abstract：:The TINU syndrome (tubulointerstitial nephritis and uveitis) was first described by Dobrin et al. in 1975. Since then, more than 50 cases have been documented each with diverse immunopathogenetic and genetic characteristics. The aim of this report is to describe a case of TINU associated with reduced complement levels...

journal_title：Nephron

authors： Conz PA,Milan M,Bragantini L,La Greca G,Bevilacqua PA

更新日期：2001-11-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-...

journal_title：Nephron

authors： Elias AN,Vaziri ND,Pandian MR,Powers DR,Domurat E

更新日期：1988-01-01 00:00:00

abstract：:Permanent loss of the ultrafiltration (UF) capacity of the peritoneum has been observed with an increasing frequency among our patients treated by long-term intermittent (IPD) and/or continuous ambulatory peritoneal dialysis (CAPD). The analysis of various characteristics of our PD population (patients age, dialysis t...

journal_title：Nephron

authors： Slingeneyer A,Canaud B,Mion C

更新日期：1983-01-01 00:00:00

abstract：:5 cases of severe acute renal failure caused by ethyl alcohol-induced rhabdomyolysis are reviewed. 4 patients were dialyzed. All patients recovered completely from the renal failure. ...

journal_title：Nephron

authors： Haapanen E,Pellinen TJ,Partanen J

更新日期：1984-01-01 00:00:00

abstract：:A previous study from our laboratory has shown that erythropoietin (EPO), beside its traditional role in erythropoiesis, acts as an alleviator of oxidative stress and inflammation in chronic hemodialysis (HD) patients, conferred in part by activated polymorphonuclear leukocytes (PMNLs). To substantiate this phenomenon...

journal_title：Nephron

authors： Sela S,Shurtz-Swirski R,Sharon R,Manaster J,Chezar J,Shkolnik G,Shapiro G,Shasha SM,Merchav S,Kristal B

更新日期：2001-07-01 00:00:00

abstract：:A 37-year-old female presented with acute onset of glomerulonephritis 10 days following an upper respiratory infection. Serum complement components were depressed and proteinuria exceeded 3.0 g daily. Renal biopsy revealed granular staining of IgG and C3 along the basement membrane as well as small amounts of IgA in a...

journal_title：Nephron

authors： Yoshizawa N,McClung JA,Ohshima S,Takahashi K,Treser G

更新日期：1986-01-01 00:00:00

abstract：:Cyclosporine (CsA) nephrotoxicity is partially mediated by renal vasoconstriction due to an imbalance between vasodilator and vasoconstrictor eicosanoids. LSL 90202 is a purified lysine salt of eicosapentaenoic acid which is a known inhibitor of renal eicosanoid synthesis. The aim of the present work was to determine ...

journal_title：Nephron

authors： Torras J,Valles J,Sanchez J,Sabate I,Seron D,Carrera M,Castelao AM,Herrero I,Puig-Parellada P,Alsina J

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Evidence indicates that hyperthermia preconditioning (HP) can be protective in kidney transplantation, possibly through increased heat shock protein (HSP) expression. A detailed study about individual HSPs and functional preservation is lacking, however. Therefore, we studied the effects of HP on kidney graf...

journal_title：Nephron

authors： Redaelli CA,Tien YH,Kubulus D,Mazzucchelli L,Schilling MK,Wagner AC

更新日期：2002-04-01 00:00:00

abstract：:Gentamicin doses of 40 mg/kg body weight/day were administered intravenously to 62 Wistar rats. Nineteen animals were also treated orally with an NaHCO3 solution in place of water. The gentamicin-treated animals showed increased albuminuria immediately after the 3rd day of treatment. The fact that this increase was ma...

journal_title：Nephron

authors： Coimbra TM,Lachat JJ

更新日期：1988-01-01 00:00:00

abstract：:Clearance and in vitro microperfusion studies were performed in rabbits to determine the effect of cisplatin on proximal straight tubule transport of calcium and magnesium. Rabbits were injected with cisplatin (2.5 mg/kg i.p. once weekly) for 3 weeks, whereas control rabbits received normal saline solution which serve...

journal_title：Nephron

authors： Wong NL,Sutton RA,Dirks JH

更新日期：1988-01-01 00:00:00

abstract：:Fibrinogen fragments (X, Y, D and E) and fibrin fragments (D-dimer and E) were examined in the urine of 52 patients with various types of renal diseases. One or more of the fibrinogen fragments were detectable in all the urine specimens. D-Dimer together with fibrinogen fragments was found in 38 of the 52 patients. Th...

journal_title：Nephron

authors： Yoshioka K,Iseki T,Akano N,Uraoka Y,Miyata H,Maki S

更新日期：1982-01-01 00:00:00

abstract：:Hypouricemia seen with hyponatremia related to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) results from an increase in uric acid renal clearance. We studied the mechanism of the increase of uric acid excretion in 6 SIADH patients through pyrazinamide (PZA), which decreases tubular secretion...

journal_title：Nephron

authors： Decaux G,Dumont I,Waterlot Y,Hanson B

更新日期：1985-01-01 00:00:00

abstract：:Clearance techniques were used to evaluate renal tubular sodium and water excretion in 4 patients with antibiotic-induced acute renal failure (ARF). Creatinine clearances and maximal urine flow rates of patients with ARF (22.6 and 5.23 ml/min, respectively) were significantly lower than control values during hypotonic...

journal_title：Nephron

authors： Hsu CH,Maletz RM,Rozas VV,Kurtz TW

更新日期：1978-01-01 00:00:00

abstract：:We encountered 11 patients with aluminum-associated bone disease (AABD), and treated them with deferoxamine (DFO). In 3 patients, a second bone biopsy was done during DFO treatment. Clinical features of AABD were compared with surgically proven secondary hyperparathyroidism (2 degrees HPT) with osteitis fibrosa on X-r...

journal_title：Nephron

authors： Iwamoto N,Ono T,Yamazaki S,Fukuda T,Kondo M,Yamamoto N,Hiratake Y,Masugi Y,Kubo Y,Hino M

更新日期：1986-01-01 00:00:00

abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha) and its soluble TNF receptors 55 and 75 (sTNFR55, sTNFR75), interleukin-1 beta (IL-1BETA) and interleukin-6 (IL-6) were measured in plasma from 13 patients with the hemolytic uremic syndrome (HUS) on admission. No significant changes in the plasma levels of TNF-alp...

journal_title：Nephron

authors： van de Kar NC,Sauerwein RW,Demacker PN,Grau GE,van Hinsbergh VW,Monnens LA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Episodes of acute kidney injury (AKI) have been associated with the development of chronic kidney disease (CKD). However, follow-up pathways for patients who have survived AKI complicating critical illness are not well established. We hypothesised that patients who had AKI requiring renal replacement therapy...

journal_title：Nephron

authors： Kirwan CJ,Blunden MJ,Dobbie H,James A,Nedungadi A,Prowle JR

更新日期：2015-01-01 00:00:00

abstract：:To test the hypothesis that acute angiotensin-converting enzyme (ACE) inhibition might predict the postoperative blood pressure outcome, a single oral dose of captopril ranging from 12.5 to 100 mg, was given to 26 patients with renovascular disease and its hypotensive effect was compared with that of surgery (21 patie...

journal_title：Nephron

authors： Salvetti A,Arzilli F,Nuccorini A,Simonini N,Glorioso N,Dessì-Fulgheri P,Madeddu P,Rappelli A

更新日期：1986-01-01 00:00:00

abstract：:29 patients receiving haemodialysis treatment for chronic renal failure were divided into two groups on the basis of the presence or absence of bone disease as defined by radiology and bone alkaline phosphatase. The group of patient with bone disease showed a significantly greater increase in protein-bound calcium dur...

journal_title：Nephron

authors： Gosling P,Naik RB,Price CP,Sammons HG,Robinson BH

更新日期：1979-01-01 00:00:00

abstract：:The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with ...

journal_title：Nephron

authors： von Hartitzsch B,Kerr DN

更新日期：1976-01-01 00:00:00

abstract：:In this study, we examined the hypothesis whether exogenous administration of L-lysine in drinking water would reduce nonenzymatic glycation of glomerular basement membrane (GBM) collagen and thus albuminuria in streptozotocin-diabetic rats. The rationale is that the administered lysine would combine with the circulat...

journal_title：Nephron

authors： Jyothirmayi GN,Modak R,Reddi AS

更新日期：2001-02-01 00:00:00

abstract：:In 25 patients with nephrotic syndromes of different origin, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion. This effect of indomethacin on GFR and proteinuria was more pronounced when the renin-angiotensin system was stimulated by a low-sodium diet and 50 m...

journal_title：Nephron

authors： Donker AJ,Brentjens JR,van der Hem GK,Arisz L

更新日期：1978-01-01 00:00:00

abstract：:The authors utilized two groups of adult male rats to study the effect of chronic-uremic toxemia on the synthesis of thyroid hormones. The control group was sham operated, while the other group had about 70--80% of the left kidney tissue surgically excised and a total right nephrectomy performed 10 days later. At the ...

journal_title：Nephron

authors： Costa e Silva A,Albuquerque RH,Santana JP

更新日期：1978-01-01 00:00:00

abstract：:We measured peritoneal losses of the active vitamin D metabolites 1,25(OH)2D3 and 24,25(OH)2D3 in patients receiving continuous ambulatory peritoneal dialysis (CAPD). The serum concentration of 24,25(OH)2D3 was considerably lower than in hemodialysis patients. The serum concentration of 1,25(OH)2D3 was undetectable an...

journal_title：Nephron

authors： Shany S,Rapoport J,Goligorsky M,Yankowitz N,Zuili I,Chaimovitz C

更新日期：1984-01-01 00:00:00

abstract：:We describe a pair of 17-year-old identical twin brothers with asymptomatic proteinuria, one of whom showed focal segmental glomerulosclerosis (FSGS) while the other showed immunoglobulin M (IgM) nephropathy. For each twin, audiological examination was normal. There was no family history of renal failure, deafness, or...

journal_title：Nephron

authors： Kim HY,Oh H,Lee YH,Huh W,Kim YG,Kim DJ,Ko YH,Kim MK

更新日期：1999-06-01 00:00:00

abstract：:In the present study the influence of a mixture of keto analogues/amino acids (KA) on PTH levels in 18 RDT patients was examined. Ten of them were treated with KA over a period of 3 months, while the other 8 patients served as control group. The KA-treated patients showed a significant fall in PTH and plasma phosphate...

journal_title：Nephron

authors： Lindenau K,Kokot F,Fröhling PT

更新日期：1986-01-01 00:00:00

abstract：:The number of mast cells in the skin was evaluated in 25 patients with end-stage renal failure on different treatment modality (conservative, hemodialysis and peritoneal dialysis). According to the presence of pruritus, uremic patients were divided into two groups: group A, 13 patients with diffuse pruritus, and group...

journal_title：Nephron

authors： Dimković N,Djukanović L,Radmilović A,Bojić P,Juloski T

更新日期：1992-01-01 00:00:00

abstract：:A case of inferior vena caval compression by hepatic cysts as a complication of adult polycystic kidney disease is presented and its management is discussed. ...

journal_title：Nephron

authors： Yaqoob M,Saffman C,Finn R,Carty AT

更新日期：1990-01-01 00:00:00

abstract：:A 65-year-old man with sclerosing mesenteritis developed the nephrotic syndrome. Percutaneous renal biopsy revealed classical histologic findings of minimal change nephropathy with a mild interstitial nephritis. Immunomodulation with prednisone led to a rapid and complete remission of the proteinuria but did not alter...

journal_title：Nephron

authors： Vernace MA,Bellucci AG,Mossey RT,Susin M,Mailloux LU,Wilkes BM,Katz S,Eskreis D

更新日期：1996-01-01 00:00:00

abstract：:CBA/CaH-kdkd mice develop hereditary tubulointerstitial disease with mononuclear cell infiltration and cyst formation, possibly representing a model of human nephronophthisis. The purpose of the present investigation was to examine the components of the fibrotic changes which typically develop in the kidneys of these ...

journal_title：Nephron

authors： Sibalic V,Sun L,Sibalic A,Oertli B,Ritthaler T,Wüthrich RP

更新日期：1998-11-01 00:00:00