Permanent loss of ultrafiltration capacity of the peritoneum in long-term peritoneal dialysis: an epidemiological study.

Abstract:

:Permanent loss of the ultrafiltration (UF) capacity of the peritoneum has been observed with an increasing frequency among our patients treated by long-term intermittent (IPD) and/or continuous ambulatory peritoneal dialysis (CAPD). The analysis of various characteristics of our PD population (patients age, dialysis techniques, peritoneal infection rate and treatment duration) indicates that the incidence of this complication increases exponentially with the duration of PD, the loss of UF capacity being observed after a shorter period in CAPD than in IPD. These observations suggest that long-term irrigation of the peritoneal cavity leads to a progressive deterioration of the peritoneum resulting in its altered permeability with loss of the ability to ultrafiltrate; the cause of this abnormality is as yet unknown.

journal_name

Nephron

journal_title

Nephron

authors

Slingeneyer A,Canaud B,Mion C

doi

10.1159/000182927

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

133-8

issue

2

eissn

1660-8151

issn

2235-3186

journal_volume

33

pub_type

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