Abstract:
:The size distribution pattern of circulating rPRL was studied in intact control (C) rats and in three uremic models, namely urine autoinfusion (UA), bilateral ureteral ligation (BUL), and bilateral nephrectomy (BNx). Plasmas were chromatographed by gel filtration in Sephadex G-100. Rat PRL was measured by RIA. The rPRL levels as well as the size distribution pattern of UA were similar to that of C. BUL and BNx showed a similar degree of hyperprolactinemia which corresponded to an increase in little rPRL. The results suggest that acute uremic hyperprolactinemia seems to be the result of accumulation of little rPRL. Acute uremia by itself does not increase rPRL plasma levels nor does it seem to affect the size distribution pattern of circulating rPRL.
journal_name
Nephronjournal_title
Nephronauthors
Martin-Oar JE,Cachofeiro MV,Rodriguez-Puyol D,Hernando L,López-Novoa JMdoi
10.1159/000183306subject
Has Abstractpub_date
1984-01-01 00:00:00pages
188-92issue
3eissn
1660-8151issn
2235-3186journal_volume
38pub_type
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