Renal tubular sodium and water excretion in antibiotic-induced nephrotoxicity. Renal function in antibiotic nephrotoxicity.

abstract：:Circumstantial evidence that pIgA has a key role in glomerular injury of IgAN is now strong. Although the answers to the questions posed in this review are necessarily incomplete, they do indicate that (1) pIgA is a major component of mesangial IgA. (2) circulating pIgA is increased and this pIgA is particularly enhan...

journal_title：Nephron

authors： Harper SJ,Feehally J

更新日期：1993-01-01 00:00:00

abstract：:We measured levels of platelet-derived microparticles (PMP), which have coagulative activity and are produced by platelet activation or physical stimulation, and CD62P/CD63-positive platelets in patients with diabetes mellitus to determine their clinical significance and effects on complications of diabetes including ...

journal_title：Nephron

authors： Omoto S,Nomura S,Shouzu A,Hayakawa T,Shimizu H,Miyake Y,Yonemoto T,Nishikawa M,Fukuhara S,Inada M

更新日期：1999-01-01 00:00:00

abstract：:3-Deoxyglucosone (3-DG) has been identified as an intermediate of the Maillard reaction in vitro. We measured serum 3-DG levels using gas chromatography/mass spectrometry and found a marked elevation in serum 3-DG levels in uremic patients compared with healthy subjects. The uremic patients with diabetes showed signif...

journal_title：Nephron

authors： Niwa T,Takeda N,Miyazaki T,Yoshizumi H,Tatematsu A,Maeda K,Ohara M,Tomiyama S,Niimura K

更新日期：1995-01-01 00:00:00

abstract：:DNA-anti-DNA cold precipitable complexes (CPC) isolated from 21 patients with systemic lupus erythematosus were tested for their ability to stimulate polymorphonuclear leukocyte (PMN) chemotaxis and to activate complement in vitro. The complexes activated complement in 20 out of 21 cases and stimulated PMN chemotaxis ...

journal_title：Nephron

authors： Losito A,Cecchini C,Pittavini L,Zampi I

更新日期：1982-01-01 00:00:00

abstract：:The protective efficacy of three schedules of a recombinant hepatitis B vaccine was evaluated in 42 patients undergoing dialysis at a teaching hospital. The rate of seroconversion after vaccination was highest (82.3%) among the recipients of three 20-micrograms doses (i.e. double the conventional dose for healthy adul...

journal_title：Nephron

authors： Mitwalli A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Complete remission (CR) and partial remission (PR) are beneficial to the long-term outcome of patients with idiopathic membranous nephropathy (iMN). However, we are lacking in studies that evaluate the clinical predictors of response to treatment with prednisone plus cyclophosphamide (CP). The objectives of ...

journal_title：Nephron

authors： Li S,Wang L,Zhang M,Zhou W,Fang W,Wang Q,Qi C,Mou S,Shao X,Ni Z

更新日期：2017-01-01 00:00:00

abstract：:Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission ...

journal_title：Nephron

authors： Nair RB,Date A,Kirubakaran MG,Shastry JC

更新日期：1987-01-01 00:00:00

abstract：:Cadmium-induced renal effects were followed (1989) in 16 workers previously exposed to cadmium, who had been shown 5 years earlier to have had tubular damage; all but 1 worker had persistent tubular damage (beta 2-microglobulin > 60 micrograms/mmol creatinine). The mean glomerular filtration rate (GFR) decreased from ...

journal_title：Nephron

authors： Järup L,Persson B,Edling C,Elinder CG

更新日期：1993-01-01 00:00:00

abstract：:From July 1984 to December 1987, 9 patients with lupus nephritis did not respond to the administration of two courses of methylprednisolone pulse therapy and cyclophosphamide treatment for 56 days. Therefore, high-dose intravenous human gamma-globulin (IVIG) was administrated. Before IVIG therapy, renal biopsy showed ...

journal_title：Nephron

authors： Lin CY,Hsu HC,Chiang H

更新日期：1989-01-01 00:00:00

abstract：:Serum leptin concentrations in normal humans have been reported to correlate with the body mass index (BMI) as well as with the body fat mass. In this study, we measured serum leptin concentrations in 107 patients on hemodialysis, 30 of whom had diabetes mellitus as the cause, and examined the clinical significance. F...

journal_title：Nephron

authors： Nakazono H,Nagake Y,Ichikawa H,Makino H

更新日期：1998-09-01 00:00:00

abstract：:Kidney biopsy remains the gold standard for uncovering the pathogenesis of acute and chronic kidney diseases. However, the ability to perform high resolution, quantitative, molecular and cellular interrogation of this precious tissue is still at a developing stage compared to other fields such as oncology. Here, we di...

journal_title：Nephron

authors： Winfree S,Dagher PC,Dunn KW,Eadon MT,Ferkowicz M,Barwinska D,Kelly KJ,Sutton TA,El-Achkar TM

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:In an attempt to decrease mortality in patients with end-stage renal disease, an increase in the lifetime of these patients without much focus on health-related quality of life (HRQOL) was pursued for a long period of time. However, lately, an improvement in the quality of this extended lifetime has focuse...

journal_title：Nephron

authors： Grincenkov FR,Fernandes N,Pereira Bdos S,Bastos K,Lopes AA,Finkelstein FO,Pecoits-Filho R,Qureshi AR,Divino-Filho JC,Bastos MG

更新日期：2015-01-01 00:00:00

abstract：:Glomerular morphological changes produced by 5-hour intravenous infusion of endotoxin (40 micrograms/kg/h) were studied in 57 rabbits. During endotoxin infusion all animals developed signs of endotoxemia, anemia, and transient leukopenia and thrombocytopenia. Acute renal failure also developed in all animals. By light...

journal_title：Nephron

authors： Bertani T,Abbate M,Zoja C,Corna D,Remuzzi G

更新日期：1989-01-01 00:00:00

abstract：:4 patients on regular dialysis were studied by the echocardiographic method during ultrafiltration and dialysis performed sequentially according to two different protocols. Blood pressure, heart rate, cardiac output, stroke volume, systolic and diastolic dimension of the left ventricle, systolic and diastolic volumes ...

journal_title：Nephron

authors： Cini G,Camici M,Pentimone F,Palla R

更新日期：1982-01-01 00:00:00

abstract：:IgA nephropathy besides exhibiting a characteristic geographical distribution has been noted to have a low incidence in the blacks of the USA. There is a paucity of data on IgA nephropathy in the blacks of Africa. We report our findings among the blacks and compare these with Indians. An analysis of the primary glomer...

journal_title：Nephron

authors： Seedat YK,Nathoo BC,Parag KB,Naiker IP,Ramsaroop R

更新日期：1988-01-01 00:00:00

abstract：:The present study was aimed to determine the effect of caffeine on the development of renal hypertension. Two-kidney, 1-clip (2K1C) hypertension and deoxycorticosterone acetate (DOCA, 200 mg/kg, subcutaneous implantation)-salt (0.9% NaCl drinking) hypertension were instituted in Sprague-Dawley rats. They were then gro...

journal_title：Nephron

authors： Choi KC,Lee J,Moon KH,Park KK,Kim SW,Kim NH

更新日期：1993-01-01 00:00:00

abstract：:It has been reported that calcium deposition and calcium content in cultured human aortic smooth muscle cells (SMC) increased when the cells are incubated in a medium with a high phosphate concentration (2 mM). To determine the cellular components or soluble factors contributing to the deposition, we cultured commerci...

journal_title：Nephron

authors： Watanabe Y,Suzuki M,Oyama Y,Kusano E,Tamba K,Iimura O,Ito C,Imai M,Asano Y

更新日期：2002-12-01 00:00:00

abstract：:To understand the regulation of vasopressin receptors in an animal model of hypertension, localization and age-related changes in renal arginine vasopressin (AVP) receptors in spontaneously hypertensive rats (SHR) were investigated using in vitro (macro) autoradiography and a radiolabeled receptor assay. Autoradiograp...

journal_title：Nephron

authors： Hosoya M,Ogura T,Watanabe H,Ota Z,Kageyama Z

更新日期：1996-01-01 00:00:00

abstract：:The ability of cultured peripheral-blood mononuclear cells (PBMC) to release interleukin-1 alpha and beta (IL-1 alpha, IL-1 beta) in response to concanavalin A (con A) was investigated in patients with chronic renal failure (CRF) and in renal transplant recipients. Mean IL-1 alpha level released by PBMC of healthy sub...

journal_title：Nephron

authors： Kang XX,Hirano T,Oka K,Tamaki T,Sakurai E,Kaji N,Yoshida M,Kozaki M

更新日期：1991-01-01 00:00:00

abstract：:To estimate food sensitization, the human basophil degranulation test (HBDT), usually used for allergy diagnosis, was performed in 34 idiopathic nephrotic syndrome (INS) patients, classified as minimal change glomerular disease, with or without atopic manifestations, and in 19 blood donors; five food allergens (wheat ...

journal_title：Nephron

authors： Lagrue G,Heslan JM,Belghiti D,Sainte-Laudy J,Laurent J

更新日期：1986-01-01 00:00:00

abstract：:Mitochondria contain electron-dense particles, partly composed of an amorphous form of calcium phosphate. We have used electron microscopy from percutaneous renal biopsy material to analyze mitochondrial granulation in the proximal renal tubule of nonuremic and uremic children. Based on a technique of cutting mitochon...

journal_title：Nephron

authors： Whitney JO,Goodman JR,Piel CF

更新日期：1979-01-01 00:00:00

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:Platelet-activating factor (PAF) belongs to a new class of lipid chemical inflammatory mediators described as acetyl glyceryl ether phosphorylcholine. Although PAF has been implicated in kidney injury, its role in renal immune injury has not been clearly defined yet. We studied the levels of PAF in the plasma and urin...

journal_title：Nephron

authors： Iatrou C,Moustakas G,Antonopoulou S,Demopoulos CA,Ziroyiannis P

更新日期：1996-01-01 00:00:00

abstract：:Serum prolactin levels were elevated in male Sprague-Dawley rats with acute renal failure induced by glycerol administration. Specific prolactin binding to kidney membrane preparations was reduced in glycerol and antirat glomerular basement membrane serum-treated rats, after morphological and biochemical acute renal f...

journal_title：Nephron

authors： Dobbie JW,Mountjoy K,Cowden EA,Allison ME,Ratcliffe JG

更新日期：1981-01-01 00:00:00

abstract：:Diabetic nephropathy is the leading cause of kidney failure. Treatments with drugs that block the renin-angiotensin system have proven beneficial in slowing kidney disease progression among those with diabetes; their benefit is limited and they do not stop disease progression. Despite multiple clinical trials of vario...

journal_title：Nephron

authors： Toto RD

更新日期：2017-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：:Human peritoneal mesothelial cells lie on a basement membrane-like material consisting of fibronectin (FN), type I collagen (CI), type III collagen (CIII) and laminin (LA). To understand how these extracellular matrix (ECM) proteins affect mesothelial cell behavior, we investigated their effect on the adhesion and pro...

journal_title：Nephron

authors： Yen CJ,Fang CC,Chen YM,Lin RH,Wu KD,Lee PH,Tsai TJ

更新日期：1997-01-01 00:00:00

abstract：:Pericardial drainage via percutaneous catheter placement and local nonabsorbable steroid instillation was employed as definitive therapy for uremic patients who had intractable pericardial effusions. Twelve patients are reported. Prior daily dialysis, and in one case systemic steroids, were not curative. 11 of 12 case...

journal_title：Nephron

authors： Buselmeier TJ,Simmons RL,Najarian JS,Mauer SM,Matas AJ,Kjellstrand CM

更新日期：1976-01-01 00:00:00

abstract：:We studied the expression of Mac-1 on granulocytes (flow cytometry) from 9 patients (27 examinations) during hemodialysis with cuprophane membranes (CuM). Samples were drawn before dialysis and from the arterial and venous lines at 5, 15 and 180 min. Granulocytopenia was most pronounced after 15 min of treatment. Mac-...

journal_title：Nephron

authors： Lundahl J,Hed J,Jacobson SH

更新日期：1992-01-01 00:00:00

abstract：:The effects of free radicals on the development of crystals attached to the living epithelium have been studied using an experimental model that enables close simulation of the conditions prevailing in the kidney. The results obtained clearly demonstrate that free radical-damaged cells produce a favorable environment ...

journal_title：Nephron

authors： Grases F,García-Ferragut L,Costa-Bauzá A

更新日期：1998-01-01 00:00:00