Mizoribine ameliorates the tubulointerstitial fibrosis of obstructive nephropathy.

abstract：:Prolongation of repolarization dispersion (QT interval dispersion) measured from the 12-lead surface ECG has been associated with sudden cardiac death and ventricular tachyarrhythmias in a variety of cardiac disorders. The aim of our study was to assess the effects of hemodialysis (HD) and continuous ambulatory perito...

journal_title：Nephron

authors： Kantarci G,Ozener C,Tokay S,Bihorac A,Akoğlu E

更新日期：2002-08-01 00:00:00

abstract：:To explain the occurrence of tubular and glomerular proteinuria in patients with primarily tubular or glomerular dysfunction, it is usually assumed that the mechanisms responsible for the renal tubular transport of small and large proteins are different. The present in vivo study does not support this hypothesis since...

journal_title：Nephron

authors： Bernard A,Viau C,Ouled A,Lauwerys R

更新日期：1987-01-01 00:00:00

abstract：:Patients with familial lecithin-cholesterol acyltransferase (LCAT) deficiency very often show progressive glomerulosclerosis with evolution to end-stage disease. High levels of an abnormal lipoprotein (lipoprotein X) cause glomerular capillary endothelial damage. The ultrastructural study of renal biopsy specimens sho...

journal_title：Nephron

authors： Sessa A,Battini G,Meroni M,Daidone G,Carnera I,Brambilla PL,Viganò G,Giordano F,Pallotti F,Torri Tarelli L,Calabresi L,Rolleri M,Bertolini S

更新日期：2001-07-01 00:00:00

abstract：:Isolated hindquarters of bilaterally nephrectomized and sham-operated rats were perfused in the presence and absence of 14C-labelled serine, respectively. After a perfusion period of 30 min 14C-serine was 4,074 +/- 270 dpm/ml in the perfusion medium of sham-operated animals and decreased to 2,800 +/- 190 dpm/ml in the...

journal_title：Nephron

authors： Djovkar A,Hörl WH,Heidland A

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Acid-base disturbances are frequent in critically ill patients. Arterial blood gas (ABG) is the gold standard in the diagnosis of these disturbances, but it is invasive with potential hazards. For patients with a central venous catheter, venous blood gas (VBG) sampling may be an alternative, less-invasive di...

journal_title：Nephron

authors： Schrauben SJ,Negoianu D,Costa C,Cohen RM,Goldfarb S,Fuchs BD,Berns JS

更新日期：2018-01-01 00:00:00

abstract：:Fibrinogen fragments (X, Y, D and E) and fibrin fragments (D-dimer and E) were examined in the urine of 52 patients with various types of renal diseases. One or more of the fibrinogen fragments were detectable in all the urine specimens. D-Dimer together with fibrinogen fragments was found in 38 of the 52 patients. Th...

journal_title：Nephron

authors： Yoshioka K,Iseki T,Akano N,Uraoka Y,Miyata H,Maki S

更新日期：1982-01-01 00:00:00

abstract：:HCV is seen as an emergent problem in Dialysis Units; in fact, the patients of these centers are at high risk for blood-transmitted infections, through coming microepidemies. For this reason and using the same method, we have studied the prevalence of anti-HCV and virus-derived hepatitis in a dialytic population of 10...

journal_title：Nephron

authors： Scotto G,Savastano AM,Forcella M,Tantimonaco G,Amato G,Salatino G,Pappani A,Stella I

更新日期：1992-01-01 00:00:00

abstract：:Cyclosporine (CsA) nephrotoxicity is partially mediated by renal vasoconstriction due to an imbalance between vasodilator and vasoconstrictor eicosanoids. LSL 90202 is a purified lysine salt of eicosapentaenoic acid which is a known inhibitor of renal eicosanoid synthesis. The aim of the present work was to determine ...

journal_title：Nephron

authors： Torras J,Valles J,Sanchez J,Sabate I,Seron D,Carrera M,Castelao AM,Herrero I,Puig-Parellada P,Alsina J

更新日期：1994-01-01 00:00:00

abstract：:To probe renal hemodynamic measurements in relation to simultaneous systemic hemodynamic measurements in normal, adult, conscious dogs on a magnesium-deficient diet, 6 experimental animals were given 4 weeks of a magnesium-deficient diet compared to 9 animals whose dietary magnesium was normal. Systemic hemodynamics w...

journal_title：Nephron

authors： Zawada ET Jr,TerWee JA,McClung DE

更新日期：1988-01-01 00:00:00

abstract：:Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...

journal_title：Nephron

authors： de Paoli Vitali E,Ricci G,Perini L,Malacarne F,Vedovato M,Guerra G,Dapporto M,Gilli P

更新日期：1996-01-01 00:00:00

abstract：:Cardiovascular disease is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Epidemiological and clinical studies have shown that this is most frequently related to damage of large conduit arteries. Macrovascular disease develops rapidly in uremic patients and is responsible for ...

journal_title：Nephron

authors： London GM

更新日期：2000-02-01 00:00:00

abstract：:Males on long-term dialysis tend to develop more severe forms of acquired cystic disease of the kidney than females. The severity of the disease is unaffected by therapeutic modality, either hemodialysis or CAPD, however, cystic transformation becomes less extensive after successful renal transplantation. The fundamen...

journal_title：Nephron

authors： Ishikawa I

更新日期：1991-01-01 00:00:00

abstract：:To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...

journal_title：Nephron

authors： Fukagawa M,Kitaoka M,Yi H,Fukuda N,Matsumoto T,Ogata E,Kurokawa K

更新日期：1994-01-01 00:00:00

abstract：:A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism, presenting severe hyponatremia, is described. A 57-year-old man complaining of nausea, vomiting and fatigability was admitted to our hospital because of hyponatremia (114 mEq/I). The low levels of serum cortisol and urinary 17-OHCS suggested gluc...

journal_title：Nephron

authors： Okada K,Takahashi S

更新日期：1996-01-01 00:00:00

abstract：:The techniques of bonding of anionic antibiotics by treatment with cationic surfactants were applied to continuous ambulatory peritoneal dialysis (CAPD) catheters. The elution of 14C-penicillin from tridodecylmethylammonium chloride (TDMAC) treated silicone elastomer catheters in dialysis solution was biphasic, with 9...

journal_title：Nephron

authors： Trooskin SZ,Donetz AP,Baxter J,Harvey RA,Greco RS

更新日期：1987-01-01 00:00:00

abstract：:Survival after serum creatinine exceeded 10.0 mg/100 ml was increased if one peritoneal dialysis was performed. After one peritoneal dialysis 'survival' of 62 patients to the present time, death or the next dialysis averaged 119 days; median survival was 28 days. Characteristics of prolonged survivors were persisten...

journal_title：Nephron

authors： Maher JF,Ahearn DJ,Bryan CW,Nolph KD

更新日期：1975-01-01 00:00:00

abstract：:To determine whether the chelation of aluminium enhances the haemopoietic response to recombinant human erythropoietin (r-HuEPO), desferrioxamine (DFO) at a dose of 20-30 mg/kg was given to 7 of 17 transfusion-dependent haemodialysis patients treated with r-HuEPO (40 units/kg/dialysis i.v.). The two randomly allocated...

journal_title：Nephron

authors： Roger SD,Stewart JH,Harris DC

更新日期：1991-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:To determine the role of vasoactive peptides such as endothelin (ET), calcitonin gene-related peptide (CGRP) and human atrial natriuretic peptide (hANP) in the regulation of blood pressure in uremic patients, and to determine the effect of various types of dialyzer membranes on hemodialysis (HD)-induced changes in pla...

journal_title：Nephron

authors： Niwa T,Fujishiro T,Uema K,Tsuzuki T,Tominaga Y,Emoto Y,Miyazaki T,Maeda K

更新日期：1993-01-01 00:00:00

abstract：:The biochemistry and function of vanadate and its possible role in health as well as in disease remains one of the most fascinating stories in biology. This review has surveyed the pertinent literature regarding its effect in the normal kidney and other tissues. While inhibition of the Na(+)-K+ ATPase enzyme was the f...

journal_title：Nephron

authors： Dafnis E,Sabatini S

更新日期：1994-01-01 00:00:00

abstract：:The relationship between glycosaminoglycans and beta 2-microglobulin, glycosaminoglycans and N-acetyl-beta-D-glucosaminidase as well as the relationship between the chondroitin sulfate/heparan sulfate ratio and SDS electrophoresis in the urine of subjects from the endemic area of Balkan nephropathy was studied in orde...

journal_title：Nephron

authors： Juretić D,Cvoriscec D,Vuković-Holjevac A,Benković J,Lipovac K,Stavljenić A

更新日期：1993-01-01 00:00:00

abstract：:Three unusual cases are described which demonstrated hypomagnesemia and symptoms resembling magnesium deficiency syndrome. The hypomagnesemia was most likely secondary to urinary losses from diuresis following release of post-renal obstruction and renal homotransplantation. Heretofore, this association has not been de...

journal_title：Nephron

authors： Davis BB,Preuss HG,Murdaugh HV Jr

更新日期：1975-01-01 00:00:00

abstract：:Pulmonary calcifications are known to occur in patients with chronic renal failure. Recently, scintigrams with bone-seeking radionuclides have been used to detect subclinical pulmonary calcium deposits. We studied 18 children on maintenance dialysis without evidence of pulmonary calcification on chest X-ray. Four chil...

journal_title：Nephron

authors： Drachman R,Baillet G,Gagnadoux MF,de Vernejoul P,Broyer M

更新日期：1986-01-01 00:00:00

abstract：:Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...

journal_title：Nephron

authors： David-Walek T,Niederstadt C,Rob PM,Fricke L,Latta K,Steinhoff J,Stange EF

更新日期：2001-01-01 00:00:00

abstract：:Serial changes in plasma of renin concentration (PRC), renin-substrate concentration (PSC) and renin activity (PRA) were followed in rats during glycerol-induced acute renal failure. There was an early but transient increase in PRC and a more delayed and prolonged rise in PSC. PRA began to rise a few hours after glyce...

journal_title：Nephron

authors： Carvalho JS,Page LB

更新日期：1978-01-01 00:00:00

abstract：:In pharmacologic doses E series prostaglandins attenuate the development of immune complex nephritis. We studied the effect of the dietary prostaglandin precursor linoleic acid on murine apoferritin-induced immune complex glomerulonephritis. High, normal, or low linoleic acid diets were fed to mice for 4 weeks prior t...

journal_title：Nephron

authors： Kher V,Barcelli U,Weiss M,Pollak VE

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:Non-alcoholic fatty liver disease (NAFLD) is recognised to be a strong risk factor for causing cardiovascular disease (CVD) and chronic kidney disease (CKD), independent of the presence of diabetes mellitus. The association of NAFLD with outcomes in patients with diabetic kidney disease (DKD) has been v...

journal_title：Nephron

authors： Chinnadurai R,Chrysochou C,Kalra PA

更新日期：2019-01-01 00:00:00

abstract：:The renal cortex of anesthetized dogs was found to contain per gram lyophilized dry weight 9.5+/-0.6 micronmol ATP, 3.2+/-0.5 MICRONMOL ADP, 0.68+/-0.3 MICRONMOL AMP, and 22.5+/-4.4 micronmol Pi. These amounts were unchanged by the administration of moderate amounts of saline or hypertonic mannitol in load doses of ab...

journal_title：Nephron

authors： Urbaitis BK,Blake WD

更新日期：1977-01-01 00:00:00

abstract：:Dopexamine hydrochloride is a synthetic dopamine analogue recently developed to improve myocardial and renal performance in patients suffering from low cardiac output states. The present study was designed to assess the pharmacological profile and the anatomical localization of [3H]-dopexamine binding sites within the...

journal_title：Nephron

authors： Napoleone P,Cavallotti C,Ricci A,Amenta F

更新日期：1993-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a worldwide public health problem associated with a high prevalence of cardiovascular disease (CVD) and impaired quality of life. Previous research for preventing loss of glomerular filtration rate (GFR) has focused on reducing blood pressure (BP) and proteinuria. Angiotensin converting...

journal_title：Nephron

authors： Ahmed A,Jorna T,Bhandari S

更新日期：2016-01-01 00:00:00