Peritoneal dialysis fluid inhibition of polymorphonuclear leukocyte respiratory burst activation is related to the lowering of intracellular pH.

abstract：:We investigated the best time of administration of desferrioxamine (DFO) with respect to the dialysis session, using the approach of the stochastic dynamic system, integrated with the classical pharmacokinetic models. In the 6 patients studied, the mean arrival times of DFO, aluminoxamine (AlO) and ferrioxamine (FO) w...

journal_title：Nephron

authors： Andriani M,Nordio M,Saporiti E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. METHODS:A home hemodialysis program was started in November 1998 in the University of Torino, Italy (2...

journal_title：Nephron

authors： Piccoli GB,Bermond F,Mezza E,Quaglia M,Pacitti A,Jeantet A,Segoloni GP

更新日期：2002-10-01 00:00:00

abstract：:To investigate autonomic mechanisms underlying persistent hypotension in long-term hemodialysis patients, high-frequency (HF, > 0.15 Hz) and low-frequency (LF, 0.04-0.15 Hz) components of heart rate variability and plasma noradrenaline were analyzed in 10 persistently hypotensive hemodialysis patients (group H), 11 no...

journal_title：Nephron

authors： Takahashi H,Matsuo S,Toriyama T,Kawahara H,Hayano J

更新日期：1996-01-01 00:00:00

abstract：:Previous reports on the nephritogenic and immunological enhancing capacity of posttransplant circulating immune complexes (CICs) are conflicting and have been confined to the study of acute rejection episode (AR). This study was undertaken to assess the nephritogenicity of CICs in patients undergoing accelerated acute...

journal_title：Nephron

authors： Jordan SC,Sakai R,Ettenger RB,Fine RN

更新日期：1982-01-01 00:00:00

abstract：:The physicians in charge of 15 German hemodialysis units furnished data on 713 dialysis patients. Data relating to the vocational status were examined for 612 patients aged 60 years or below. It was found that the current working status varies with psychological and social factors. The data show that the vocational st...

journal_title：Nephron

authors： Tews HP,Schreiber WK,Huber W,Zelt J,Ritz E

更新日期：1980-01-01 00:00:00

abstract：:In the present study the influence of a mixture of keto analogues/amino acids (KA) on PTH levels in 18 RDT patients was examined. Ten of them were treated with KA over a period of 3 months, while the other 8 patients served as control group. The KA-treated patients showed a significant fall in PTH and plasma phosphate...

journal_title：Nephron

authors： Lindenau K,Kokot F,Fröhling PT

更新日期：1986-01-01 00:00:00

abstract：:Diabetic nephropathy (DN), a distinct manifestation of diabetic kidney disease, affects approximately 30% of patients with diabetes. While most attention has been focused on glomerular changes related to DN, there is growing evidence that tubulopathy is a key feature in the pathogenesis of this disease. The renal prox...

journal_title：Nephron

authors： Hinden L,Tam J

更新日期：2019-01-01 00:00:00

abstract：:Diabetic nephropathy is the leading cause of kidney failure. Treatments with drugs that block the renin-angiotensin system have proven beneficial in slowing kidney disease progression among those with diabetes; their benefit is limited and they do not stop disease progression. Despite multiple clinical trials of vario...

journal_title：Nephron

authors： Toto RD

更新日期：2017-01-01 00:00:00

abstract：:The purpose of the study was to investigate the effects of parathyroid hormone (PTH) infusion on antioxidant enzyme activity and lipid peroxidation of erythrocytes in five-sixths nephrectomized (Nx) rats. Five-sixths Nx rats had a higher osmotic fragility in red blood cells (RBC). Thyroparathyroidectomy (TPTX) effecti...

journal_title：Nephron

authors： Chen SM,Young TK

更新日期：1996-01-01 00:00:00

abstract：:The efficacy of simvastatin, a competitive inhibitor of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, was investigated in 12 patients treated with continuous ambulatory peritoneal dialysis (CAPD), displaying hypercholesterolemia and moderate hypertriglyceridemia. After a 4-week placebo period, simvastatin was admi...

journal_title：Nephron

authors： Wanner C,Lubrich-Birkner I,Summ O,Wieland H,Schollmeyer P

更新日期：1992-01-01 00:00:00

abstract：:The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...

journal_title：Nephron

authors： Descamps-Latscha B,Goldfarb B,Nguyen AT,Landais P,London G,Haeffner-Cavaillon N,Jacquot C,Herbelin A,Kazatchkine M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...

journal_title：Nephron

authors： Shaw C,Steenkamp R,Davenport A

更新日期：2015-01-01 00:00:00

abstract：:Permanent loss of the ultrafiltration (UF) capacity of the peritoneum has been observed with an increasing frequency among our patients treated by long-term intermittent (IPD) and/or continuous ambulatory peritoneal dialysis (CAPD). The analysis of various characteristics of our PD population (patients age, dialysis t...

journal_title：Nephron

authors： Slingeneyer A,Canaud B,Mion C

更新日期：1983-01-01 00:00:00

abstract：:This study aims to raise the possibility of methylguanidine, a peroxidative product of creatinine, as a measure of the peroxidative state. As a known standard, we measured the inhibitory effect of uremic serum on the NADPH-dependent microsomal lipid peroxidation. This is an established method for evaluating the peroxi...

journal_title：Nephron

authors： Nagase S,Aoyagi K,Hirayama A,Gotoh M,Ueda A,Tomida C,Kikuchi H,Takemura K,Koyama A

更新日期：1996-01-01 00:00:00

abstract：:We have previously documented the importance of tumor necrosis factor (TNF) alpha in the pathogenesis of nephrotoxic-serum nephritis in rats. In this study, we evaluated the possible relevance of the well-established cytocidal TNF activity to the mechanism of glomerular injury by assessing sensitivity of rat mesangial...

journal_title：Nephron

authors： Hruby ZW,Cybulsky AV,Lowry RP

更新日期：1990-01-01 00:00:00

abstract：:The incidence of acute tubular necrosis (need for hemodialysis immediately after transplantation) and its severity (the number of days dialysis was needed) were studied in 299 patients who were randomized prior to transplantation into undergoing splenectomy or not having splenectomy. There was no difference in the inc...

journal_title：Nephron

authors： Pru CE,Fryd DS,Kjellstrand CM

更新日期：1984-01-01 00:00:00

abstract：:Malignant hypertension and high plasma renin activity was found in a 39-year-old woman with an aldosterone-producing adenoma. Only 3 similar cases have been previously reported, and all patients died before or after identification of the adenoma. The present paper documents the first reported case of a successfully ma...

journal_title：Nephron

authors： Ideishi M,Kishikawa K,Kinoshita A,Sasaguri M,Ikeda M,Takebayashi S,Arakawa K

更新日期：1990-01-01 00:00:00

abstract：AIMS:There is a trend toward deferring the initiation of chronic dialysis until absolutely indicated. This strategy, however, might lead to increased uncertainties in the timing of dialysis access creation prior to dialysis onset for patients approaching end-stage renal disease (ESRD), and the impact of which on hard e...

journal_title：Nephron

authors： Chen YM,Wang YC,Hwang SJ,Lin SH,Wu KD

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...

journal_title：Nephron

authors： Ghouti-Terki L,Chasseuil E,Rabot N,Paintaud G,François M,Birmelé B,Darrouzain F,Büchler M,Halimi JM,Ternant D

更新日期：2017-01-01 00:00:00

abstract：:A study was conducted to determine whether intraperitoneal and oral administration of formalin-fixed gram-negative bacteria induced immunohistologically and ultrastructurally evident glomerular deposition of IgA and C3 in C3H/HeN mice. Separate treatments with strains of Pseudomonas aeruginosa, Escherichia coli, Haemo...

journal_title：Nephron

authors： Endo Y,Kanbayashi H,Hara M

更新日期：1993-01-01 00:00:00

abstract：:We have determined the plasma levels of endothelin-1 (ET-1) in patients with end-stage renal disease treated with continuous ambulatory peritoneal dialysis (CAPD). In 10 CAPD patients mean plasma ET levels (7.01 +/- 0.5 pg/ml) were found higher than in normal subjects (3.6 +/- 0.6 pg/ml). Peritoneal clearance of ET-1 ...

journal_title：Nephron

authors： Vlassopoulos D,Deray G,Carayon A,Maistre G,Jacobs C

更新日期：1995-01-01 00:00:00

abstract：:Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...

journal_title：Nephron

authors： Venkat Raman G,Pead L,Lee HA,Maskell R

更新日期：1986-01-01 00:00:00

abstract：:We examined the ultrastructure of the bovine glomerular basement membrane (GBM) and tubular basement membrane (TBM) using ultra-high-resolution scanning electron microscopy after conductive staining without metal coating. Purified basement membranes (BMs) were obtained by sonication and acellular BMs by detergent trea...

journal_title：Nephron

authors： Yamasaki Y,Makino H,Ota Z

更新日期：1994-01-01 00:00:00

abstract：:The techniques of bonding of anionic antibiotics by treatment with cationic surfactants were applied to continuous ambulatory peritoneal dialysis (CAPD) catheters. The elution of 14C-penicillin from tridodecylmethylammonium chloride (TDMAC) treated silicone elastomer catheters in dialysis solution was biphasic, with 9...

journal_title：Nephron

authors： Trooskin SZ,Donetz AP,Baxter J,Harvey RA,Greco RS

更新日期：1987-01-01 00:00:00

abstract：:Hyperparathyroidism is a common problem for patients on renal replacement therapy programs. Many long-term dialysis patients require parathyroidectomy while on dialysis. Some patients, however, despite severe renal osteodystrophy, are transplanted, and in these a large proportion show a slow resolution of bony problem...

journal_title：Nephron

authors： Goldsmith D,Owen WJ

更新日期：2001-09-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：:We report a case of graft intolerance syndrome in which transplant nephrectomy was performed 11 years after kidney transplantation. A 46-year-old man was admitted to our hospital in February 2018 with a mild fever, left lower abdominal pain, and gross hematuria with enlargement of the transplanted kidney. Urinary trac...

journal_title：Nephron

authors： Tomonari M,Kobayashi A,Yamamoto I,Hatanaka S,Kawabe M,Yamakawa T,Katsumata H,Katsuma A,Mafune A,Nakada Y,Koike Y,Miki J,Kimura T,Tanno Y,Yamamoto H,Yokoo T

更新日期：2020-01-01 00:00:00

abstract：:A new case of acute renal failure after rifampicin is presented, together with a review of the 36 similar cases published up to date in the literature. Evidence is provided that irregularities in drug intake, either as true intermittent treatment or as discontinuation of continuous therapy, play an important role in t...

journal_title：Nephron

authors： Nessi R,Bonoldi GL,Redaelli B,di Filippo G

更新日期：1976-01-01 00:00:00

abstract：:Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...

journal_title：Nephron

authors： Thatcher R,Whitworth JA,Skinner SL

更新日期：1982-01-01 00:00:00

abstract：:Dysfunction of the host defense against infection in hemodialysis (HD) patients has major clinical and socioeconomic implications. T helper type 1 (Th1) and type 2 (Th2) cytokines are implicated in regulating the immune responses and, therefore, may be involved in impaired status. The present study was designed to exa...

journal_title：Nephron

authors： Daichou Y,Kurashige S,Hashimoto S,Suzuki S

更新日期：1999-01-01 00:00:00