Abstract:
:Hypertension secondary to renal transplantation was studied in our experimental model in the rat. In this model an intravenous injection of donor strain blood into recipients of allogeneic donor kidneys prior to transplantation was used to prolong the allograft survival. A reduced renal function associated with the hypertension was suggestive of incomplete prevention of the rejection process. We studied the effect of cyclosporin A, either alone or as adjuvant immunosuppressive therapy, on renal function and systolic blood pressure. Either way, cyclosporin A resulted in normotensive allograft recipients and in a better function of the graft when compared with recipients pretreated with donor strain blood only.
journal_name
Nephronjournal_title
Nephronauthors
de Keijzer MH,Provoost AP,van Aken M,Kort WJ,Wolff ED,Molenaar JCdoi
10.1159/000183428subject
Has Abstractpub_date
1985-01-01 00:00:00pages
57-62issue
1eissn
1660-8151issn
2235-3186journal_volume
40pub_type
杂志文章相关文献
NEPHRON文献大全abstract::The authors describe an unusual case of radial artery pseudoaneurysm in a patient with a Brescia-Cimino fistula. Evaluation of a pulsatile mass on the patient's forearm which occurred after hemodialysis led to a nondiagnostic fistulogram. Color flow ultrasound was helpful in identifying the nature of the abnormality, ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188958
更新日期:1996-01-01 00:00:00
abstract::Mean renal blood flow (MRBF), cortical blood flow (CBF), glomerular filtration rate (GFR), heart rate, arterial blood pressure, Na+ and K+ excretion were determined before and 10 min after intrarenal administration of dihydroergocristine (0.017 mg/kg b.w.) in 13 patients suffering from liver cirrhosis. Cardiac output ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182519
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND/AIMS:Cardiac surgery-associated severe acute kidney injury (SAKI) is associated with high mortality and poor quality of life. A prognostic score for SAKI may enable prevention of complications. METHODS:This observational study of 2,552 patients undergoing cardiac surgery from January 2006 to December 2011 i...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000499345
更新日期:2019-01-01 00:00:00
abstract::Hypouricemia seen with hyponatremia related to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) results from an increase in uric acid renal clearance. We studied the mechanism of the increase of uric acid excretion in 6 SIADH patients through pyrazinamide (PZA), which decreases tubular secretion...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183365
更新日期:1985-01-01 00:00:00
abstract::A reduction in the serum urate concentration in hyperuricemic subjects can be achieved by increasing the renal excretion of uric acid, by inhibiting its synthesis, or by a combination of both modalities. The three most commonly used hypouricemic drugs are probenecid, sulfinpyrazone and allopurinol. Each drug has been ...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000180439
更新日期:1975-01-01 00:00:00
abstract::Experiences with peritonitis in a continuous ambulatory peritoneal dialysis (CAPD) program at a single center over 8 years were reviewed. Home-acquired peritonitis rates have been less than 1 episode per patient year since 1982. Gram-positive organisms continue to account for most episodes in a similar proportion. Act...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183807
更新日期:1986-01-01 00:00:00
abstract::The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188255
更新日期:1994-01-01 00:00:00
abstract::An 'epidemic' of aseptic peritonitis occurred in our peritoneal dialysis unit, affecting 5 of 20 patients. Acute and convalescent viral titers were normal in all 5. The peritoneal fluid of the affected patients was not tested for endotoxin, but endotoxin was found in subsequent dialysis fluids from two machines in the...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181728
更新日期:1979-01-01 00:00:00
abstract::We present a 57-year-old man with end-stage renal failure due to chronic glomerulonephritis, who had been on hemodialysis for 13.5 years and had suffered from recurrent painful swelling of the left leg for 4.7 years. A diagnosis of deep venous thrombosis was made by the phlebography. Coagulation studies showed decreas...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187835
更新日期:1994-01-01 00:00:00
abstract::The Spanish brush goat (Capra hiricus) was studied as an animal model for the anephric state. This rugged animal has a hardy appetite and offers ready blood access for dialysis and sampling. BUN, plasma creatinine and potassium could be brought to normal values by daily hemodialysis. Continual weight loss, severe anem...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181750
更新日期:1980-01-01 00:00:00
abstract::The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...
journal_title:Nephron
pub_type: 杂志文章,多中心研究
doi:10.1159/000187095
更新日期:1992-01-01 00:00:00
abstract::A 16-year-old female with acro-renal-ocular syndrome complicated by ventricular septal defect is described. Renal biopsy was performed for the first time in this syndrome, and the results suggested that proteinuria and renal dysfunction were caused by chronic pyelonephritis secondary to malrotation of the kidney and a...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000185264
更新日期:1989-01-01 00:00:00
abstract::The present prospective study was conducted in order to establish the relationship between complement activation and stimulation of phagocyte oxidative metabolism observed in long-term hemodialysis (HD) patients during the early phase of dialysis with cellulosic membranes. Two groups of 10 randomized (HD) patients tre...
journal_title:Nephron
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000186565
更新日期:1991-01-01 00:00:00
abstract::HLA antigens of Japanese patients with primary glomerulopathies were determined, and the frequency of each HLA antigen was compared with that of Japanese normal controls. IgA nephropathy with HLA-DR4, idiopathic membraneous glomerulopathy with DR2, lipoid nephrosis with DRw53 and poststreptococcal glomerulonephritis w...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184089
更新日期:1987-01-01 00:00:00
abstract::The daily loss of apolipoproteins into the dialysate from 5 patients on continuous ambulatory peritoneal dialysis (CAPD) was measured. The mean excretion of apolipoprotein (apo) AI and apo AII, major proteins of high-density lipoproteins (HDL), were 84 and 17 mg/day, respectively, while that of apo B, a major protein ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185289
更新日期:1989-01-01 00:00:00
abstract::The possible role of altered renal prostaglandin metabolism in the generation of post-obstruction diuresis (POD) was examined in 16 adult male Sprague-Dawley rats. Inhibition of cyclooxygenase by the administration of a combination of two nonsteroidal anti-inflammatory drugs (NSAID), meclofenamate and indomethacin in ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186766
更新日期:1992-01-01 00:00:00
abstract::The high blood flow rate/gram of kidney tissue supplies mainly the renal cortex. The net effect of the interaction of the renin-angiotensin system, the kallikrein-kinin system and prostaglandins is to autoregulate renal blood flow within a narrow range. Drugs and neurogenic factors also influence renal hemodynamics. T...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182057
更新日期:1981-01-01 00:00:00
abstract::Both the plasma determinations of erythropoietic (EPO) and transferrin receptor (TfR) would provide a good characterization of anemia especially when mixed erythron disorders underlie, such as in renal failure. Immunologic assays of EPO and TfR, as well as standard hematologic determinations (hematocrit, reticulocyte ...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000188938
更新日期:1996-01-01 00:00:00
abstract::351 sera from 27 human recipients of renal allografts and 21 healthy blood donors were assayed for circulating immune complexes by the Clq solid-phase radioimmune assay. Increased Clq-binding activity (Clq-BA) was detected in pretransplant sera from 5 patients with chronic pyelonephritis (PN) and 3 patients with chron...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182133
更新日期:1981-01-01 00:00:00
abstract::The effects of acute beta 2-type adrenoreceptor activation with intravenous albuterol on plasma and urinary sodium, potassium, calcium, magnesium, phosphate and lithium were investigated in 9 volunteers during acute hydration. When compared with the control infusion with inactive vehicle, beta 2-type adrenoreceptor ac...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187403
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Episodes of acute kidney injury (AKI) have been associated with the development of chronic kidney disease (CKD). However, follow-up pathways for patients who have survived AKI complicating critical illness are not well established. We hypothesised that patients who had AKI requiring renal replacement therapy...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000371448
更新日期:2015-01-01 00:00:00
abstract::A 58-year-old woman who suffered from a heterozygous Fabry's disease and immune complex crescentic glomerulonephritis (GN) is reviewed. The diagnosis was made on the basis of the pathologic findings and peripheral leukocyte alpha-galactosidase activity. Light microscopy revealed a vacuolization of epithelial cells and...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000063287
更新日期:2002-10-01 00:00:00
abstract::Pericardial drainage via percutaneous catheter placement and local nonabsorbable steroid instillation was employed as definitive therapy for uremic patients who had intractable pericardial effusions. Twelve patients are reported. Prior daily dialysis, and in one case systemic steroids, were not curative. 11 of 12 case...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180622
更新日期:1976-01-01 00:00:00
abstract::Malignant hypertension and high plasma renin activity was found in a 39-year-old woman with an aldosterone-producing adenoma. Only 3 similar cases have been previously reported, and all patients died before or after identification of the adenoma. The present paper documents the first reported case of a successfully ma...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185866
更新日期:1990-01-01 00:00:00
abstract::Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182848
更新日期:1982-01-01 00:00:00
abstract::The cytoprotective effect of ulinastatin was studied in LLC-PK1 cells treated with antimycin A, gentamicin, or cisplatin. All of the three agents induced a concentration-dependent increase in the release of lactate dehydrogenase and a decrease in the amount of remaining protein. In the cell injury models treated with ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000190195
更新日期:1997-01-01 00:00:00
abstract::329 patients were evaluated from 1978 to 1990. 40 new cases of non-A non-B hepatitis were observed, all regarding patients on hemodialysis. Since the beginning of 1989, we introduced measures to limit the diffusion of the virus: reduction to a minimum of blood transfusions and a new disinfection protocol for monitors,...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186929
更新日期:1992-01-01 00:00:00
abstract::Animal models are essential tools to understand the mechanisms underlying the development and progression of renal disease and to study potential therapeutic approaches. Recently, interventional models suitable to induce acute and chronic kidney disease in the mouse have become a focus of interest due to the wide avai...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000445171
更新日期:2016-01-01 00:00:00
abstract::In a 21-year-old Caucasian women with von Hippel-Lindau disease, norepinephrine-producing adrenal pheochromocytoma was identified as the underlying cause of severe hypertension. She was found to have extremely elevated levels of circulating renin and aldosterone, and she was markedly hypokalemic. Administration of cap...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187071
更新日期:1992-01-01 00:00:00
abstract::Propranolol-induced hypoglycemia in hemodialysis patients has been increasingly recognized. We studied the effects of a nonselective beta-blocker (propranolol) and a beta 1-selective-blocker (metoprolol) on glucose metabolism during pharmacologic hyperglucagonemia in these patients. cAMP and insulin responses to gluca...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183367
更新日期:1985-01-01 00:00:00