Lipoprotein and apolipoprotein losses during continuous ambulatory peritoneal dialysis.

abstract：:In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis ...

journal_title：Nephron

authors： Fuss M,De Backer M,Brauman J,Nijs-Dewolf N,Manderlier T,Brauman H,Corvilain J

更新日期：1976-01-01 00:00:00

abstract：:Dialysate effluent protein content was measured in 22 patients undergoing continuous ambulatory peritoneal dialysis (9 with and 13 without previous peritonitis). The average amount of protein in those patients without peritonitis was 1.3 g/2 liters exchanged over a 6-hour period, while that of patients with previous p...

journal_title：Nephron

authors： Katirtzoglou A,Oreopoulos DG,Husdan H,Leung M,Ogilvie R,Dombros N

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Previous studies showed that ceftriaxone can cause acute kidney injury (AKI) in the pediatric population. This study proposed a cellular model of crystalline nephropathy in ceftriaxone-associated AKI and explored the related pathophysiology by using a proteomic approach. METHODS:Ceftriaxone was crystallized...

journal_title：Nephron

authors： Chatchen S,Pongsakul N,Srisomsap C,Chiangjong W,Hongeng S,Svasti J,Chutipongtanate S

更新日期：2018-01-01 00:00:00

abstract：:Abnormalities in plasma composition of essential fatty acids (EFAs) may be associated with the etiology of pruritus and other skin problems in patients undergoing hemodialysis. To study whether an oral supplementation with omega-6 (n-6) EFAs would restore deranged plasma EFAs and ameliorate skin symptoms, 9 and 7 dial...

journal_title：Nephron

authors： Yoshimoto-Furuie K,Yoshimoto K,Tanaka T,Saima S,Kikuchi Y,Shay J,Horrobin DF,Echizen H

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND/AIMS:Children with a solitary functioning kidney have a risk of renal injury caused by hyperfiltration. Timely intervention with renin-angiotensin inhibitors may be beneficial. We examined whether trajectory of estimated glomerular filtration rate (eGFR) would predict renal injury, defined as microalbuminuri...

journal_title：Nephron

authors： Matsumura K,Sugii K,Awazu M

更新日期：2018-01-01 00:00:00

abstract：:Decreased serum levels of high-density lipoprotein cholesterol (HDL-C) are a well-known risk factor for coronary heart disease (CHD) in the general population and have been suggested as one of the best predictor of CHD after renal transplantation. However, very heterogeneous HDL-C levels have been reported in renal tr...

journal_title：Nephron

authors： Radeau T,Vohl MC,Houde I,Lachance JG,Noël R,Després JP,Douville P,Bergeron J

更新日期：2000-04-01 00:00:00

abstract：:The study aimed to evaluate the behavior of alpha-glutathione S-transferase (alpha-GST) in the serum of hemodialysis patients with hepatitis C virus (HCV) infection following treatment with high-dose IFN-alpha-2b. Ten patients with detected anti-HCV antibodies and HCV RNA by RT-PCR were selected and treated with high-...

journal_title：Nephron

authors： Boran M,Cetin S

更新日期：1999-01-01 00:00:00

abstract：:In pharmacologic doses E series prostaglandins attenuate the development of immune complex nephritis. We studied the effect of the dietary prostaglandin precursor linoleic acid on murine apoferritin-induced immune complex glomerulonephritis. High, normal, or low linoleic acid diets were fed to mice for 4 weeks prior t...

journal_title：Nephron

authors： Kher V,Barcelli U,Weiss M,Pollak VE

更新日期：1985-01-01 00:00:00

abstract：:Proteoglycans constitute a heterogenous group of complex macromolecules, consisting of a backbone core protein and a variable number of sulfated polysaccharide side chains covalently linked to the core. A dual function for these polyanionic glycosaminoglycans in kidney physiology has been proposed: to maintain a fixed...

journal_title：Nephron

authors： Pyke C,Kristensen P,Ostergaard PB,Oturai PS,Rømer J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this is not known. One clue might lie with pattern recognition receptors (PRRs), which are triggers of ischemic i...

journal_title：Nephron

authors： DeWolf SE,Shigeoka AA,Scheinok A,Kasimsetty SG,Welch AK,McKay DB

更新日期：2017-01-01 00:00:00

abstract：:In 92 renal transplant recipients, serum or plasma levels of neopterin were significantly elevated during pretransplant uremia, rejection, cyclosporin A induced nephrotoxicity and cytomegalovirus (CMV) infections. In patients with normal serum creatinine (less than 115 mumol/l) 71% had elevated serum neopterin levels....

journal_title：Nephron

authors： Bäckman L,Ringdén O,Björkhem I

更新日期：1987-01-01 00:00:00

abstract：:The present study was aimed to determine the effect of caffeine on the development of renal hypertension. Two-kidney, 1-clip (2K1C) hypertension and deoxycorticosterone acetate (DOCA, 200 mg/kg, subcutaneous implantation)-salt (0.9% NaCl drinking) hypertension were instituted in Sprague-Dawley rats. They were then gro...

journal_title：Nephron

authors： Choi KC,Lee J,Moon KH,Park KK,Kim SW,Kim NH

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Glomerular hyperfiltration (GH) is a hallmark of renal dysfunction in diabetes and obesity. Recent clinical trials demonstrated that SGLT2 inhibitors are renoprotective, possibly by abating hyperfiltration. The present review considers the current evidence for a cause-to-effect relationship between hyperfilt...

journal_title：Nephron

authors： Chagnac A,Zingerman B,Rozen-Zvi B,Herman-Edelstein M

更新日期：2019-01-01 00:00:00

abstract：:The three-dimensional ultrastructure of glomerular basement membrane (GBM) in surgically resected human kidneys was observed by the quick-freezing and deep-etching method. In three layers of human GBM, the middle layer exhibited polygonal meshwork structures, which were composed of fine fibrils. In addition, the outer...

journal_title：Nephron

authors： Moriya T,Ohno S,Yajima Y

更新日期：1995-01-01 00:00:00

abstract：:To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

journal_title：Nephron

authors： Duan SB,Wu HW,Luo JA,Liu FY

更新日期：1999-01-01 00:00:00

abstract：:The effect of ischemia on renal blood flow (RBF) in the rat has been an unsettled question. This study used a totally extractable indicator, radioactive microspheres, with a reference arterial sample, to study RBF quantitatively 10 and 60 min after 1 h of unilateral renal artery clamping in anesthetized, heparinized r...

journal_title：Nephron

authors： Riley AL

更新日期：1978-01-01 00:00:00

abstract：:An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, theref...

journal_title：Nephron

authors： Ehrenfeld M,Licht A,Stessman J,Yanko L,Rosenmann E

更新日期：1977-01-01 00:00:00

abstract：:Radial arterial spasm in uremic patients undergoing construction of internal arteriovenous (AV) dialysis fistulas was investigated transcutaneously using ultrasonic Doppler flowmetry. In 5 of 15 patients, radial arterial blood flow was significantly decreased 5 min after anastomosing the radial cephalic vein with the ...

journal_title：Nephron

authors： Owada A,Saito H,Mochizuki T,Tanaka M,Otsuka M,Yokoyama Y,Fukuda S

更新日期：1993-01-01 00:00:00

abstract：:To determine the cytokines responsible for the increase in production of IgA in patients with IgA nephropathy (IgAN), the roles of interleukin-4 (IL-4) and soluble CD23 (sCD23) were examined. Peripheral blood mononuclear cells (PBMCs) and serum were obtained from 24 patients with IgAN and 14 patients with non-IgA prol...

journal_title：Nephron

authors： Yano N,Endoh M,Takemura F,Naka R,Kashem A,Nomoto Y,Sakai H

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...

journal_title：Nephron

authors： Covic AC,Sprague SM,Rastogi A,Ketteler M,Walpen S,Perrin A,Floege J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Haemophilus influenzae infection is a mild and self-limited disease in the healthy population. However, it may show an aggressive course in the immunocompromised state which underlines the importance of vaccination against this agent. On the other hand, posttranplant immunosuppression may impair immune respo...

journal_title：Nephron

authors： Sever MS,Yildiz A,Eraksoy H,Badur S,Yüksel-Onel D,Görçin B,Türk S,Erkoç R

更新日期：1999-01-01 00:00:00

abstract：:Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a new autosomal form of hypophosphatemic rickets, recently described. This disease is characterized, and differs from other forms of hereditary hypophosphatemic rickets and/or osteomalacia by increased serum levels of 1,25-dihydroxyvitamin D, hypercalci...

journal_title：Nephron

authors： Tieder M,Arie R,Bab I,Maor J,Liberman UA

更新日期：1992-01-01 00:00:00

abstract：:The clinicopathological findings of isolated mesangial C3d deposition in the absence of other complement components or immunoglobulins are summarized. 55 out of 242 individual human renal biopsies examined by immunoperoxidase microscopy had isolated C3d deposition. This group consisted of 12 patients with chronic glom...

journal_title：Nephron

authors： Doi T,Kanatsu K,Suehiro F,Nagai H,Yoshida H,Hamashima Y

更新日期：1987-01-01 00:00:00

abstract：:3-Deoxyglucosone (3-DG) has been identified as an intermediate of the Maillard reaction in vitro. We measured serum 3-DG levels using gas chromatography/mass spectrometry and found a marked elevation in serum 3-DG levels in uremic patients compared with healthy subjects. The uremic patients with diabetes showed signif...

journal_title：Nephron

authors： Niwa T,Takeda N,Miyazaki T,Yoshizumi H,Tatematsu A,Maeda K,Ohara M,Tomiyama S,Niimura K

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND/AIM:The impact of dialysis membrane permeability on neutrophil transmigration properties in vitro was examined in the present study. This issue has not been fully scrutinized before. METHODS:We studied the capacity of neutrophils collected from a group of dialysis patients randomly treated with cuprophan, l...

journal_title：Nephron

authors： Moshfegh A,Jacobson SH,Halldén G,Thylén P,Lundahl J

更新日期：2002-08-01 00:00:00

abstract：:Efficacy and safety of a low-molecular-weight heparin (LMWH) were studied in 33 stable maintenance hemodialysis patients who had a bleeding tendency on unfractionated heparin. The optimal dose of LMWH for each patient was titrated before the study; the mean total LMWH dosage was 1,152 +/- 574 IU. No major bleeding or ...

journal_title：Nephron

authors： Leu JG,Chiang SS,Lin SM,Pai JK,Jiang WW

更新日期：2000-12-01 00:00:00

abstract：:X-linked nephrogenic diabetes insipidus (NDI) is a rare disease caused by mutations in the vasopressin V2 receptor (AVPR2) gene. We analyzed the AVPR2 gene in 6 unrelated Korean families with X-linked NDI, and found 6 novel mutations. Two of them were missense point mutations, 2 were short deletions causing frameshift...

journal_title：Nephron

authors： Cheong HI,Park HW,Ha IS,Moon HN,Choi Y,Ko KW,Jun JK

更新日期：1997-01-01 00:00:00

abstract：:Classic renal tubular acidosis is characterized by a primary defect in establishment of a large hydrogen ion gradient across the distal renal tubule. Thus the development of hyperchlorenic metabolic acidosis follows. In addition, hypokalemia results from renal potassium wasting secondary hyperaldosteronism from sodium...

journal_title：Nephron

authors： Chan JC

更新日期：1979-01-01 00:00:00

abstract：:The effect of changes in the dialysate calcium concentration on calcium fractions and parathyroid hormone species in plasma during hemodialysis has been examined. C-terminal immunoreactive parathyroid hormone was suppressed when plasma calcium increased by greater than 25% whereas N-terminal fragments demonstrated an ...

journal_title：Nephron

authors： McIntosh CH,Fuchs C,Dorn D,Quellhorst E,Henning HV,Hesch RD,Scheler F

更新日期：1977-01-01 00:00:00

abstract：:This report describes the case of a 50-year-old male with end-stage renal failure accompanied with congenital heart disease and polycythemia. After he had received continuous ambulatory peritoneal dialysis for 1 year, he still remained polycythemic and his serum erythropoietin titer, assayed using fetal mouse liver ce...

journal_title：Nephron

authors： Muto S,Asano Y,Hosoda S,Shionoya S,Miura Y,Urabe A,Takaku F

更新日期：1987-01-01 00:00:00