Abstract:
:A very simple analytical procedure with dimethylmethylene blue as photometric reagent was applied for the evaluation of glycosaminoglycan (GAG) urinary excretions and concentrations in both sexes, calcium oxalate stone formers, and a control group. The GAG concentrations varied significantly in stone formers (males and females) and in the control group; moreover, in some individual cases, a deficit of urinary GAGs was clearly detected. Apart from important inhibitory effects of GAGs on heterogenous calcium oxalate nucleation, the low urinary GAG content could be the cause of a pathological epithelium, favoring stone formation. The dimethylmethylene blue method is recommended as a quick screening procedure to determine a GAG deficit.
journal_name
Nephronjournal_title
Nephronauthors
Grases F,Llompart I,Conte A,Coll R,March JGdoi
10.1159/000188306subject
Has Abstractpub_date
1994-01-01 00:00:00pages
449-53issue
4eissn
1660-8151issn
2235-3186journal_volume
68pub_type
杂志文章相关文献
NEPHRON文献大全abstract::As with many other amino acids the transport of cystine across the tubular epithelium is coupled to a parallel transport of sodium. We have studied the effect of a sodium-restricted diet on the urinary excretion of cystine in 13 patients with cystinuria, 7 of whom were treated with the SH compound tiopronin (2-mercapt...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000188760
更新日期:1995-01-01 00:00:00
abstract::Nephrotic range proteinuria occurred in a 60-year-old woman with renal artery stenosis and marked hyperreninemia. Treatment by nephrectomy produced resolution of both proteinuria and hypertension. The gradual resolution of the proteinuria postoperatively suggested the proteinuria, at least in part, came from the contr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182521
更新日期:1982-01-01 00:00:00
abstract::The physiologic action of prazosin in man was studied in 23 patients including 10 treated with prazosin plus polythiazide. Responders to prazosin alone (blood pressure fell greater than 10 mm Hg) had a decrease in peripheral resistance (p less than 0.02) and no significant change in plasma volume, while nonresponders'...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182245
更新日期:1981-01-01 00:00:00
abstract::Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000185040
更新日期:1988-01-01 00:00:00
abstract::Postnephrectomy serum has been proved to enhance proliferation of mesangial cells in culture. Studies in offspring to uninephrectomized (UNx) mothers indicate that it remains active for a long period following UNx. On the other hand, postnephrectomy renal compensatory growth in vivo is known to be completed within a s...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000044913
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000370276
更新日期:2015-01-01 00:00:00
abstract::Hypertension secondary to renal transplantation was studied in our experimental model in the rat. In this model an intravenous injection of donor strain blood into recipients of allogeneic donor kidneys prior to transplantation was used to prolong the allograft survival. A reduced renal function associated with the hy...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183428
更新日期:1985-01-01 00:00:00
abstract::Renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (RBF), glomerular filtration rate (GFR), sodium excretion (UNaV), and intrarenal distribution of blood ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000180454
更新日期:1975-01-01 00:00:00
abstract::This paper reviews the control of aldosterone secretion, including the role played by hepatic metabolic clearance, ACTH, and the renin-angiotensin system, and the interrelationships of aldosterone secretion with sodium and potassium metabolism. The physiological modulations of aldosterone secretion by the upright post...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181613
更新日期:1979-01-01 00:00:00
abstract::Serum and urinary concentrations of NCl, the non collagenous globular domain of collagen IV, were used as markers for turnover of basement membranes. NCl levels were studied in membranous glomerulonephritis and diabetic nephropathy. Thirteen patients with membranous glomerulonephritis and 8 insulin-dependent diabetic ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186511
更新日期:1991-01-01 00:00:00
abstract::HCV is seen as an emergent problem in Dialysis Units; in fact, the patients of these centers are at high risk for blood-transmitted infections, through coming microepidemies. For this reason and using the same method, we have studied the prevalence of anti-HCV and virus-derived hepatitis in a dialytic population of 10...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000186922
更新日期:1992-01-01 00:00:00
abstract::We followed renal function through the natriuretic phase of 6 occasions of drug-induced recovery from minimal lesions nephrotic syndrome (MLNS). Protein excretion started to fall 1-3 days prior to the start of the natriuresis. The natriuresis was accompanied by a rise in glomerular filtration rate (GFR, inulin clearan...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184486
更新日期:1987-01-01 00:00:00
abstract::To investigate autonomic mechanisms underlying persistent hypotension in long-term hemodialysis patients, high-frequency (HF, > 0.15 Hz) and low-frequency (LF, 0.04-0.15 Hz) components of heart rate variability and plasma noradrenaline were analyzed in 10 persistently hypotensive hemodialysis patients (group H), 11 no...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188906
更新日期:1996-01-01 00:00:00
abstract::Active (A) and inactive (I) plasma renin concentrations (PRC) were examined during haemodialysis in relation to blood pressure and body weight changes. Patients had either one (n = 15) or two (n = 51) remnant kidneys in situ, or were anephric (n = 4). 6 of the two remnant kidney patients had non-functioning renal allo...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182848
更新日期:1982-01-01 00:00:00
abstract::This report describes the case of a 50-year-old male with end-stage renal failure accompanied with congenital heart disease and polycythemia. After he had received continuous ambulatory peritoneal dialysis for 1 year, he still remained polycythemic and his serum erythropoietin titer, assayed using fetal mouse liver ce...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184292
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND/AIM:Our previous study with prevalent cases suggested that some genetic, immunological and lifestyle-related factors increased the risk of immunoglobulin A nephropathy (IgAN). To confirm this hypothesis, we conducted another case-control study. METHODS:The study included 116 incident cases and 276 sex-, age...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000046309
更新日期:2002-01-01 00:00:00
abstract::Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000182055
更新日期:1981-01-01 00:00:00
abstract::In this study we investigated the interactions between volume changes (body weight), plasma atrial natriuretic peptide (pANP) and ambulatory blood pressure (BP) in 10 patients with end-stage renal disease undergoing regular hemodialysis (HD) treatment three times weekly. Most patients retained their diurnal BP variati...
journal_title:Nephron
pub_type: 临床试验,杂志文章
doi:10.1159/000189036
更新日期:1996-01-01 00:00:00
abstract::In order to assess the effects of sodium depletion on tubular Na and H2O transport in man, renal clearance studies were performed under control conditions and after sodium depletion in 7 normal subjects. The control diet contained 250 mEq of Na daily. Sodium depletion was induced by placing subjects on a 20-mEq/day na...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000182635
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:In the last decade, great advances have been made in the field of membranous nephropathy (MN). The autoimmune nature of the disease has been confirmed with the description of diverse antigens, and few but very important prospective trials regarding treatment alternatives have been published, changing profoun...
journal_title:Nephron
pub_type: 杂志文章,评审
doi:10.1159/000506948
更新日期:2020-01-01 00:00:00
abstract::Cadmium-induced renal effects were followed (1989) in 16 workers previously exposed to cadmium, who had been shown 5 years earlier to have had tubular damage; all but 1 worker had persistent tubular damage (beta 2-microglobulin > 60 micrograms/mmol creatinine). The mean glomerular filtration rate (GFR) decreased from ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000187282
更新日期:1993-01-01 00:00:00
abstract::To clarify whether the changes of parathyroid size have any correlations with the long-term prognosis of calcitriol pulse therapy, we examined the time course of serum levels of parathyroid hormone (PTH) and size of parathyroid glands in 14 chronic dialysis patients during and after the oral calcitriol pulse therapy. ...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188261
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000453005
更新日期:2017-01-01 00:00:00
abstract::The 24-hour urinary excretion of kallikrein (K) and prostaglandin E2 (PGE2), which reflects their intrarenal synthesis, was measured in 7 normal women (NW), 10 women with essential hypertension (EH), 26 normal pregnant women (NP), 12 women with hypertension in pregnancy (HP), and 4 women with toxemia. All pregnant wom...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000183426
更新日期:1985-01-01 00:00:00
abstract::29 patients receiving haemodialysis treatment for chronic renal failure were divided into two groups on the basis of the presence or absence of bone disease as defined by radiology and bone alkaline phosphatase. The group of patient with bone disease showed a significantly greater increase in protein-bound calcium dur...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181632
更新日期:1979-01-01 00:00:00
abstract::Hypokalemia and potassium depletion are frequent complications of amphotericin B therapy. Both ischemic and gentamicin-induced renal failure is potentiated by potassium depletion; it is, therefore, possible that amphotericin B nephrotoxicity is similarly influenced. This study evaluated whether the acute nephrotoxic r...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000188590
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND/AIMS:In February 2017, our laboratory implemented an electronic AKI flagging system for primary care using the NHS England AKI detection algorithm. Our study investigated the impact on patient follow-up, hospital admission, length of stay, and mortality. METHODS:Primary care results March 2017-February 2018...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000509855
更新日期:2020-01-01 00:00:00
abstract::The clinicopathological findings of isolated mesangial C3d deposition in the absence of other complement components or immunoglobulins are summarized. 55 out of 242 individual human renal biopsies examined by immunoperoxidase microscopy had isolated C3d deposition. This group consisted of 12 patients with chronic glom...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000184339
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) patients who experience superimposed acute kidney injury (AKI) have been shown to be at higher risk of long-term sequelae of AKI when compared to those who do not experience AKI. It remains unclear whether the need for temporary dialysis intervention following superimposed AKI in...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000455749
更新日期:2017-01-01 00:00:00
abstract::Dialysate effluent protein content was measured in 22 patients undergoing continuous ambulatory peritoneal dialysis (9 with and 13 without previous peritonitis). The average amount of protein in those patients without peritonitis was 1.3 g/2 liters exchanged over a 6-hour period, while that of patients with previous p...
journal_title:Nephron
pub_type: 杂志文章
doi:10.1159/000181990
更新日期:1980-01-01 00:00:00