Vancomycin pharmacokinetics in continuous ambulatory peritoneal dialysis patients with peritonitis.

abstract：:29 patients receiving haemodialysis treatment for chronic renal failure were divided into two groups on the basis of the presence or absence of bone disease as defined by radiology and bone alkaline phosphatase. The group of patient with bone disease showed a significantly greater increase in protein-bound calcium dur...

journal_title：Nephron

authors： Gosling P,Naik RB,Price CP,Sammons HG,Robinson BH

更新日期：1979-01-01 00:00:00

abstract：:Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis. Five patients were studied before and after 1 week of dietary sodium restriction in order to examine the possibility that increased extrac...

journal_title：Nephron

authors： Schacht RG,Steele JM Jr,Lowenstein J,Baldwin DS

更新日期：1977-01-01 00:00:00

abstract：:Interleukin-6 (IL-6) was determined in serum and peritoneal dialysis effluent (PDE) of patients on chronic ambulatory peritoneal dialysis (CAPD) by a biological assay measuring the proliferation of the IL-6-dependent 7TD1 cell line. Six patients free of peritonitis displayed low but significant levels of IL-6 (mean +/...

journal_title：Nephron

authors： Goldman M,Vandenabeele P,Moulart J,Amraoui Z,Abramowicz D,Nortier J,Vanherweghem JL,Fiers W

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Scientists use preclinical models of acute kidney injury (AKI) to decipher mechanisms and develop therapy, but translation of therapies to patients remains poor. Models that better resemble patients, including those within clinical care, should be considered. SUMMARY:Mice provide many advantages to the stud...

journal_title：Nephron

authors： Billings FT 4th

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:De novo expression of CD44 is considered as a marker of parietal epithelial cell (PEC) activation. The aim of our study was to explore CD74 expression, which can form a complex with CD44, in PECs during the progression of focal segmental glomerulosclerosis (FSGS). To clarify the role of CD74 expression ...

journal_title：Nephron

authors： Yamazaki T,Sasaki S,Okamoto T,Sato Y,Hayashi A,Ariga T

更新日期：2016-01-01 00:00:00

abstract：:Proteoglycans constitute a heterogenous group of complex macromolecules, consisting of a backbone core protein and a variable number of sulfated polysaccharide side chains covalently linked to the core. A dual function for these polyanionic glycosaminoglycans in kidney physiology has been proposed: to maintain a fixed...

journal_title：Nephron

authors： Pyke C,Kristensen P,Ostergaard PB,Oturai PS,Rømer J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Chronic renal failure is commonly associated with disturbances in hypothalamic-pituitary-gonadal function. METHODS:The gonadotrophins, prolactin and estradiol or testosterone levels were measured immediately before renal transplantation, at discharge from the transplantation unit (19 +/- 8 days after Tx) an...

journal_title：Nephron

authors： Saha MT,Saha HH,Niskanen LK,Salmela KT,Pasternack AI

更新日期：2002-01-01 00:00:00

abstract：:From a review of the literature regarding kinetic models used for assessing the adequacy of hemodialysis, no definite conclusions can be drawn as to whether the classical urea kinetic model (UKM) or modified direct dialysis quantification (mDDQ) is more reliable. We compared mDDQ with classical UKM and with a modified...

journal_title：Nephron

authors： Bosticardo GM,Alloatti S

更新日期：1996-01-01 00:00:00

abstract：:The specific lipid alterations in plasma and four different tissues, as well as the activities of plasma lecithin-cholesterol acyltransferase (LCAT) and tissue lipolytic enzymes were determined in experimental nephrotic and control rats. In nephrotic rats, the cholesterol level in the heart was significantly increased...

journal_title：Nephron

authors： Agbedana ED,Yamamoto T,Moriwaki Y,Suda M,Takahashi S,Higashino K

更新日期：1993-01-01 00:00:00

abstract：:We present a 57-year-old man with end-stage renal failure due to chronic glomerulonephritis, who had been on hemodialysis for 13.5 years and had suffered from recurrent painful swelling of the left leg for 4.7 years. A diagnosis of deep venous thrombosis was made by the phlebography. Coagulation studies showed decreas...

journal_title：Nephron

authors： Maruyama H,Gejyo F,Hanano M,Arakawa M

更新日期：1994-01-01 00:00:00

abstract：:Using immunofluorescence, we studied 19 patients with IgA nephropathy to determine whether the expression of intercellular adhesion molecule (ICAM)-1 in glomeruli might reflect the disease activity. The relationship between the expression of ICAM-1 and the infiltration of lymphocytes, monocytes and polymorphonuclear l...

journal_title：Nephron

authors： Tomino Y,Ohmuro H,Kuramoto T,Shirato I,Eguchi K,Sakai H,Okumura K,Koide H

更新日期：1994-01-01 00:00:00

abstract：:136 patients on hemodialysis, 89 males and 47 females, were studied; we evaluated the index of hepatic function (SGOT and SGPT) and antibodies against HCV. We observed 42 cases of increased transaminases classified as non-A, non-B (NANB) hepatitis. Antibodies against HCV were present in 40 patients. Among 42 patients ...

journal_title：Nephron

authors： La Russa A,Bufano G,Cauzzi L,Pecchini P

更新日期：1992-01-01 00:00:00

abstract：:Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) anti-leucocyte autoantibo...

journal_title：Nephron

authors： Lobo PI,Okusa MD

更新日期：2019-01-01 00:00:00

abstract：:To understand the regulation of vasopressin receptors in an animal model of hypertension, localization and age-related changes in renal arginine vasopressin (AVP) receptors in spontaneously hypertensive rats (SHR) were investigated using in vitro (macro) autoradiography and a radiolabeled receptor assay. Autoradiograp...

journal_title：Nephron

authors： Hosoya M,Ogura T,Watanabe H,Ota Z,Kageyama Z

更新日期：1996-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection has been associated with several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) were also described in several patients with overt AIDS. We describe a patient who presented with HUS and only subsequent investigation to find the caus...

journal_title：Nephron

authors： Badesha PS,Saklayen MG

更新日期：1996-01-01 00:00:00

abstract：:The effect of intravenous 1 alpha(OH)D3 on circulating intact parathyroid hormone (PTH) and COOH-terminal immunoreactive PTH was examined in 21 patients on chronic hemodialysis. The patients were treated for 3 months with increasing doses of 1 alpha(OH)D3 under careful control of serum Ca2+. 1 alpha(OH)D3 was given in...

journal_title：Nephron

authors： Brandi L,Daugaard H,Tvedegaard E,Storm T,Olgaard K

更新日期：1989-01-01 00:00:00

abstract：:Norepinephrine (NE) content, release and uptake by brain synaptosomes are reduced in chronic renal failure (CRF), and this has been attributed to the state of secondary hyperparathyroidism. The decrease in NE content in CRF could not be explained by changes in NE uptake or release since in normal circumstances, NE con...

journal_title：Nephron

authors： Islam A,Smorgorzewski M,Zayed MA,Massry SG

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Vancomycin is usually administered after the dialysis sessions to patients undergoing hemodialysis. Administration of vancomycin during (as opposed to after) sessions would save time, and would be more acceptable to patients and staff, but may lead to vancomycin underexposure. The aim of this study was to pr...

journal_title：Nephron

authors： Ghouti-Terki L,Chasseuil E,Rabot N,Paintaud G,François M,Birmelé B,Darrouzain F,Büchler M,Halimi JM,Ternant D

更新日期：2017-01-01 00:00:00

abstract：:We have studied the interaction of the Gal-GalNAc-reactive champedak lectin-C with neuraminidase-treated and untreated IgA1 from IgA nephropathy patients. The binding ability of the lectin to untreated IgA1 from IgA nephropathy patients was significantly lower as compared to the untreated IgA1 from normal controls. Th...

journal_title：Nephron

authors： Hashim OH,Shuib AS,Chua CT

更新日期：2001-12-01 00:00:00

abstract：:Survival after serum creatinine exceeded 10.0 mg/100 ml was increased if one peritoneal dialysis was performed. After one peritoneal dialysis 'survival' of 62 patients to the present time, death or the next dialysis averaged 119 days; median survival was 28 days. Characteristics of prolonged survivors were persisten...

journal_title：Nephron

authors： Maher JF,Ahearn DJ,Bryan CW,Nolph KD

更新日期：1975-01-01 00:00:00

abstract：:Decreased serum levels of high-density lipoprotein cholesterol (HDL-C) are a well-known risk factor for coronary heart disease (CHD) in the general population and have been suggested as one of the best predictor of CHD after renal transplantation. However, very heterogeneous HDL-C levels have been reported in renal tr...

journal_title：Nephron

authors： Radeau T,Vohl MC,Houde I,Lachance JG,Noël R,Després JP,Douville P,Bergeron J

更新日期：2000-04-01 00:00:00

abstract：:Epidermal nevus syndrome is an unusual neurocutaneous disorder in which epidermal nevi are associated with abnormalities of the skeleton and central nervous system, including the eyes and somtimes the cardiovascular system. We treated a patient in whom the latter included renal artery stenosis. An 18-year-old man with...

journal_title：Nephron

authors： Aizawa K,Nakamura T,Ohyama Y,Saito Y,Hoshino J,Kanda T,Sumino H,Nagai R

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Progressive nephropathy is one of the main features of Fabry disease (FD). It has been supposed that an early phase, clinically silent disease occurs in childhood and adolescence and is characterized by glomerular hyperfiltration (HF). Surprisingly, although HF has been reported in several stu...

journal_title：Nephron

authors： Riccio E,Sabbatini M,Bruzzese D,Annicchiarico Petruzzelli L,Pellegrino A,Spinelli L,Esposito R,Imbriaco M,Feriozzi S,Pisani A,on behalf of AFFIINITY Group.

更新日期：2019-01-01 00:00:00

abstract：:The purpose of this study was to characterize renal cell carcinoma tissue by the measurement of microacoustic properties. A scanning acoustic microscope system operating in the frequency range of 100-200 MHz was employed and the attenuation constant and sound speed were measured on the two-dimensional distribution. Th...

journal_title：Nephron

authors： Sasaki H,Tanaka M,Saijo Y,Okawai H,Terasawa Y,Nitta S,Suzuki K

更新日期：1996-01-01 00:00:00

abstract：:The TINU syndrome (tubulointerstitial nephritis and uveitis) was first described by Dobrin et al. in 1975. Since then, more than 50 cases have been documented each with diverse immunopathogenetic and genetic characteristics. The aim of this report is to describe a case of TINU associated with reduced complement levels...

journal_title：Nephron

authors： Conz PA,Milan M,Bragantini L,La Greca G,Bevilacqua PA

更新日期：2001-11-01 00:00:00

abstract：:In order to clarify cellular responses in dilated renal tubules in the acute and chronic phase of ureteral obstruction, we investigated the expression of proliferating cell nuclear antigen and osteopontin (OPN) in unilateral ureteral obstruction (UUO)-treated rat kidneys. The results showed that renal epithelial cells...

journal_title：Nephron

authors： Sakai T,Tanaka H,Shirasawa T

更新日期：1997-01-01 00:00:00

abstract：:Creatinine clearance has been repeatedly measured in three groups of chronic uremics. In the first control group (31 cases), following a conventional low-protein diet, creatinine clearance declined linearly with time. In the second group (12 cases), following very low nitrogen diet supplemented with essential amino ac...

journal_title：Nephron

authors： Barsotti G,Guiducci A,Ciardella F,Giovannetti S

更新日期：1981-01-01 00:00:00

abstract：:Cardiovascular disease is the major complication and cause of mortality in the dialysis population, accounting for about 40% of deaths. Oxidative stress has been strongly implicated in the pathogenesis of these events. As patients in end-stage renal disease (ESRD) are in a state of elevated free radical activity, the ...

journal_title：Nephron

authors： Wang NP,Lim PS,Chen TT,Thien LM,Wang TH,Hsu WM

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...

journal_title：Nephron

authors： Shaw C,Steenkamp R,Davenport A

更新日期：2015-01-01 00:00:00

abstract：:The effect of ischemia on renal blood flow (RBF) in the rat has been an unsettled question. This study used a totally extractable indicator, radioactive microspheres, with a reference arterial sample, to study RBF quantitatively 10 and 60 min after 1 h of unilateral renal artery clamping in anesthetized, heparinized r...

journal_title：Nephron

authors： Riley AL

更新日期：1978-01-01 00:00:00