A rare cause of pulmonary-renal syndrome.

abstract：:Glycoprotein: galactosyl and glycoprotein: sialic acid transferase activities were measured in the serum of patients with minimal lesion nephrotic syndrome, acute renal failure, and chronic renal insufficiency of varying severity. The activity of galactosyl transferase was elevated in all patients but one. Sialic acid...

journal_title：Nephron

authors： Kirschbaum BB

更新日期：1976-01-01 00:00:00

abstract：:A gradual loss of cell viability was observed during in vitro incubation of peritoneal cells from chronically uremic mice in commercial peritoneal dialysis solutions. The magnitude of this cytotoxicity toward peritoneal cells harvested from uremic mice and controls was comparable. Resident peritoneal cells were always...

journal_title：Nephron

authors： Gallimore B,Gagnon RF,Stevenson MM

更新日期：1986-01-01 00:00:00

abstract：:Like other biguanide agents, metformin is an anti-hyperglycemic agent with lower tendency towards hypoglycemia compared to other anti-diabetic drugs. Given its favorable effects on serum lipids, obese body habitus, cardiovascular disease, and mortality, metformin is recommended as the first-line pharmacologic agent fo...

journal_title：Nephron

authors： Rhee CM,Kovesdy CP,Kalantar-Zadeh K

更新日期：2017-01-01 00:00:00

abstract：:Thrombospondin (TSP) is a multifunctional glycoprotein that is synthesized by a variety of cells including mesangial cells (MCs). To clarify the effect of TSP on the pathogenesis of diabetic nephropathy, we studied the effect of glucose concentrations on TSP synthesis in cultured human MCs. Thereafter, the effects of ...

journal_title：Nephron

authors： Tada H,Isogai S

更新日期：1998-01-01 00:00:00

abstract：:3-Deoxyglucosone (3-DG) has been identified as an intermediate of the Maillard reaction in vitro. We measured serum 3-DG levels using gas chromatography/mass spectrometry and found a marked elevation in serum 3-DG levels in uremic patients compared with healthy subjects. The uremic patients with diabetes showed signif...

journal_title：Nephron

authors： Niwa T,Takeda N,Miyazaki T,Yoshizumi H,Tatematsu A,Maeda K,Ohara M,Tomiyama S,Niimura K

更新日期：1995-01-01 00:00:00

abstract：:In order to evaluate effects of metabolic acidosis on glucose metabolism in uremia, we studied, by an intravenous glucose tolerance test (IVGTT), 46 patients with severe chronic renal failure divided into three groups according to their blood bicarbonate (BB) values: group A formed by 15 patients without or with light...

journal_title：Nephron

authors： Allegra V,Mengozzi G,Martimbianco L,Vasile A

更新日期：1993-01-01 00:00:00

abstract：:Complement factor D, a complement system serine protease, circulating in vivo as its active form, accumulates in patients with chronic renal failure. The pathophysiological role of this active protease in these patients was examined by studies on activities of excess factor D on 10 synthetic peptide substrates for som...

journal_title：Nephron

authors： Inagi R,Miyata T,Oda O,Maeda K,Inoue K

更新日期：1994-01-01 00:00:00

abstract：:351 sera from 27 human recipients of renal allografts and 21 healthy blood donors were assayed for circulating immune complexes by the Clq solid-phase radioimmune assay. Increased Clq-binding activity (Clq-BA) was detected in pretransplant sera from 5 patients with chronic pyelonephritis (PN) and 3 patients with chron...

journal_title：Nephron

authors： Kaden J,Falck P,Groth J,Mebel M

更新日期：1981-01-01 00:00:00

abstract：:A 57-year-old man with renal cell carcinoma associated with membranous glomerulonephropathy (MGN) developed a transient amelioration of the nephrotic syndrome after excision of the tumor. We tried to identify a nephritogenic tumor antigen using the immunoblotting technique in this patient with MGN, since previous stud...

journal_title：Nephron

authors： Togawa A,Yamamoto T,Suzuki H,Watanabe K,Matsui K,Nagase M,Hishida A

更新日期：2002-02-01 00:00:00

abstract：:Plasma levels of granulocyte lactoferrin, granulocyte myeloperoxidase and granulocyte elastase in complex with alpha 1-proteinase inhibitor were investigated during hemodialysis in oliguric patients following cadaveric renal transplantation (CRT). The results were compared with those of patients undergoing regular hem...

journal_title：Nephron

authors： Riegel W,Leverenz K,Schollmeyer P,Wilms H,Hörl WH

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historical...

journal_title：Nephron

authors： Shaw C,Steenkamp R,Davenport A

更新日期：2015-01-01 00:00:00

abstract：:Classic renal tubular acidosis is characterized by a primary defect in establishment of a large hydrogen ion gradient across the distal renal tubule. Thus the development of hyperchlorenic metabolic acidosis follows. In addition, hypokalemia results from renal potassium wasting secondary hyperaldosteronism from sodium...

journal_title：Nephron

authors： Chan JC

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Anemia management in chronic hemodialysis (HD) has been affected by the implementation of the prospective payment system (PPS) and changes in clinical guidelines. These factors could impact red blood cell (RBC) transfusion in HD patients. Our distinctive care system contains complete records for all RBC tran...

journal_title：Nephron

authors： Albright RC Jr,Dillon JJ,Hocum CL,Stubbs JR,Johnson PM,Hickson LJ,Williams AW,Dingli D,McCarthy JT

更新日期：2016-01-01 00:00:00

abstract：:This study was undertaken to evaluate the relation between the urinary excretion of guanidinoacetic acid (GAA) and other substances in hypertensive patients (6 with borderline hypertension and 29 with hypertension) and 12 normal controls. In 10 of the hypertensive patients, GAA was measured before and after 4 weeks of...

journal_title：Nephron

authors： Takano Y,Aoike I,Gejyo F,Arakawa M

更新日期：1989-01-01 00:00:00

abstract：:The mitochondrial DNA mutation mt.3243A>G is most commonly associated with maternally inherited diabetes and deafness (MIM 52,000), but it has protean phenotypes including renal disease due to focal segmental glomerulosclerosis. We describe monozygotic twins who both harboured this mutation and developed ESRD. Althoug...

journal_title：Nephron

authors： Shand JAD,Potter HC,Pilmore HL,Cundy T,Murphy R

更新日期：2020-01-01 00:00:00

abstract：:A simple three-pump-based system for the performance of continuous venovenous haemodialysis is described. The method employs access to the circulation via a double-lumen catheter, and by means of a standard extracorporeal peristaltic pump the blood is circulated through a haemofiltration filter. Standard solutions for...

journal_title：Nephron

authors： Møller Jensen D,Bistrup C,Pedersen RS

更新日期：1996-01-01 00:00:00

abstract：:To determine whether there are early renal function parameters (RFP) which can be monitored to rapidly detect nephrotoxicity induced by contrast media (CM), we observed RFP in 16 patients with normal renal function before and after administration of CM. Forty-eight hours after diatrizoate meglumine administration, blo...

journal_title：Nephron

authors： Duan SB,Wu HW,Luo JA,Liu FY

更新日期：1999-01-01 00:00:00

abstract：:Cyclosporine (CsA) nephrotoxicity is partially mediated by renal vasoconstriction due to an imbalance between vasodilator and vasoconstrictor eicosanoids. LSL 90202 is a purified lysine salt of eicosapentaenoic acid which is a known inhibitor of renal eicosanoid synthesis. The aim of the present work was to determine ...

journal_title：Nephron

authors： Torras J,Valles J,Sanchez J,Sabate I,Seron D,Carrera M,Castelao AM,Herrero I,Puig-Parellada P,Alsina J

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Cyst infection is a frequent and serious complication of autosomal dominant polycystic kidney disease (ADPKD) that is often difficult to treat. However, the factors influencing cyst infection are still unknown. Therefore, we investigated clinical factors related to the duration of hospitalization and death d...

journal_title：Nephron

authors： Suwabe T,Ubara Y,Hayami N,Yamanouchi M,Hiramatsu R,Sumida K,Sawa N,Sekine A,Kawada M,Hasegawa E,Hoshino J,Takaichi K

更新日期：2019-01-01 00:00:00

abstract：:The daily loss of apolipoproteins into the dialysate from 5 patients on continuous ambulatory peritoneal dialysis (CAPD) was measured. The mean excretion of apolipoprotein (apo) AI and apo AII, major proteins of high-density lipoproteins (HDL), were 84 and 17 mg/day, respectively, while that of apo B, a major protein ...

journal_title：Nephron

authors： Saku K,Sasaki J,Naito S,Arakawa K

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Several studies have provided convincing evidence that in apparently healthy subjects elevated serum levels of plasma C-reactive protein (CRP) are associated with an increased risk of experiencing myocardial infarction and sudden cardiac death. It has been claimed that, in dialytic patients, the hepatic synt...

journal_title：Nephron

authors： Panichi V,Migliori M,De Pietro S,Taccola D,Bianchi AM,Giovannini L,Norpoth M,Metelli MR,Cristofani R,Bertelli AA,Sbragia G,Tetta C,Palla R,Colombo R

更新日期：2002-08-01 00:00:00

abstract：:A retrospective study of 100 patients followed for 1-4 years after successful renal transplantation was undertaken to assess the amelioration of previously present metabolic bone disease and to determine the risk factors associated with the development of osteonecrosis. 42% of patients showed some evidence of bony abn...

journal_title：Nephron

authors： Gottlieb MN,Stephens MK,Lowrie EG,Griffiths HJ,Kenzora J,Strom TB,Lazarus JM,Tilney NL,Merrill JP

更新日期：1978-01-01 00:00:00

abstract：:Acute renal failure due to tubulo-interstitial nephritis developed in a 15-year-old girl. The disease was accompanied by uveitis and an inflammatory syndrome, consisting of a markedly increased erythrocyte sedimentation rate and high serum gamma globulin levels. The nephropathy as well as the inflammatory syndrome sub...

journal_title：Nephron

authors： Vanhaesebrouck P,Carton D,De Bel C,Praet M,Proesmans W

更新日期：1985-01-01 00:00:00

abstract：:Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...

journal_title：Nephron

authors： Venkat Raman G,Pead L,Lee HA,Maskell R

更新日期：1986-01-01 00:00:00

abstract：:An animal model with experimental uremia is an important research tool for the study of the sequence of pathophysiological events taking place in the uremic syndrome. An appreciable number of animal models and methods for the induction of chronic uremia have been published. It is surprising that no such method has bee...

journal_title：Nephron

authors： Gabizon D,Goren E,Shaked U,Averbukh Z,Rosenmann E,Modai D

更新日期：1985-01-01 00:00:00

abstract：:The methodology for the collection, extraction, separation and measurement of urinary angiotensin II [the octapeptide, ANG(1-8)] is described. To determine the origin of urinary ANG(1-8), mean arterial pressure, renal hemodynamics and the arterial, renal venous and urinary concentrations of ANG(1-8) were examined prio...

journal_title：Nephron

authors： Reams G,Villarreal D,Wu Z,Bauer JH

更新日期：1994-01-01 00:00:00

abstract：:A 55-year-old white male, with silicosis diagnosed 10 years earlier, presented massive proteinuria with microscopic hematuria, moderate renal failure and distal polyneuropathy. Bilateral renal angiography showed multiple intraparenchymal saccular aneurysms. Renal biopsy disclosed a focal segmental necrotizing glomerul...

journal_title：Nephron

authors： Arnalich F,Lahoz C,Picazo ML,Monereo A,Arribas JR,Martínez Ara J,Vázquez JJ

更新日期：1989-01-01 00:00:00

abstract：:A new case of acute renal failure after rifampicin is presented, together with a review of the 36 similar cases published up to date in the literature. Evidence is provided that irregularities in drug intake, either as true intermittent treatment or as discontinuation of continuous therapy, play an important role in t...

journal_title：Nephron

authors： Nessi R,Bonoldi GL,Redaelli B,di Filippo G

更新日期：1976-01-01 00:00:00

abstract：:To eliminate the discomfort caused by surgical methods and the risks involved using the trocar, for 1 year we have been using a new technique for insertion of peritoneal catheters (PC). We devised a steel instrument, vaguely resembling a rhinoscope, composed of two semicones. The handles are connected by a screw to pe...

journal_title：Nephron

authors： Di Paolo N,Manganelli A,Strappaveccia F,De Mia M,Gaggiotti E

更新日期：1985-01-01 00:00:00

abstract：:To verify the action of heparin on peritoneal transport, we selected 20 patients on acute peritoneal dialysis and performed two 2-hour cycles with 2,000 cm3 of a 1.5% solution, adding 2,000 units of heparin to the second cycle. The patients were also randomized into 2 groups: group A, adding 1.5 mg gentamycin/kg to th...

journal_title：Nephron

authors： Ponce SP,Barata JD,Santos JR

更新日期：1985-01-01 00:00:00