Risks of Metformin in Type 2 Diabetes and Chronic Kidney Disease: Lessons Learned from Taiwanese Data.

abstract：:Clearance techniques were used to evaluate renal tubular sodium and water excretion in 4 patients with antibiotic-induced acute renal failure (ARF). Creatinine clearances and maximal urine flow rates of patients with ARF (22.6 and 5.23 ml/min, respectively) were significantly lower than control values during hypotonic...

journal_title：Nephron

authors： Hsu CH,Maletz RM,Rozas VV,Kurtz TW

更新日期：1978-01-01 00:00:00

abstract：:A 66-year-old white man presented with severe chronic renal failure. He had no past or present symptomatic glucose intolerance nor a family history of diabetes mellitus. Several fasting plasma glucose determinations, hemoglobin Alc and an oral glucose tolerance test were normal. Funduscopic ophthalmoscopy and retinal ...

journal_title：Nephron

authors： da Silva EC,Saldanha LB,Pestalozzi MS,del Bueno IJ,Barros RT,Marcondes M,Nussenzveig I

更新日期：1992-01-01 00:00:00

abstract：:Using immunofluorescence, we studied 19 patients with IgA nephropathy to determine whether the expression of intercellular adhesion molecule (ICAM)-1 in glomeruli might reflect the disease activity. The relationship between the expression of ICAM-1 and the infiltration of lymphocytes, monocytes and polymorphonuclear l...

journal_title：Nephron

authors： Tomino Y,Ohmuro H,Kuramoto T,Shirato I,Eguchi K,Sakai H,Okumura K,Koide H

更新日期：1994-01-01 00:00:00

abstract：:Diseases affecting both the lung and the kidney have grave prognosis and serious diagnostic and therapeutic consequences. Here, 3 cases of pulmonary-renal syndrome caused by antiphospholipid syndrome are reported. The patients presented with dyspnea, renal insufficiency, pulmonary infiltrates on chest X-ray and areas ...

journal_title：Nephron

authors： Henning BF,Gröne HJ,Tepel M,Büchner N,Kirchner J,Zidek W

更新日期：2002-07-01 00:00:00

abstract：:Eighteen hemodialysis, 12 chronic ambulatory peritoneal dialysis (CAPD), and 20 renal transplant patients performed maximal treadmill exercise tests. Heart rates and blood pressures were determined every minute and maximal oxygen consumption was measured directly. Exercise capacity as measured by VO2 max is low in dia...

journal_title：Nephron

authors： Painter P,Messer-Rehak D,Hanson P,Zimmerman SW,Glass NR

更新日期：1986-01-01 00:00:00

abstract：:Here, we review the most recent findings on the effects of SARS-CoV-2 infection on kidney diseases, including acute kidney injury, and examine the potential effects of ARBs on the outcomes of patients with COVID-19. Lastly, we discuss the clinical management of COVID-19 patients with existing chronic renal disorders, ...

journal_title：Nephron

authors： Perico L,Benigni A,Remuzzi G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is a cytokine which plays an important role in the division, proliferation and migration of endothelial cells. In the kidney, VEGF expression is found in glomerular podocytes and in tubular epithelial cells, which may result in acute inflammatory reactions. METHODS:...

journal_title：Nephron

authors： Prakash S,Agrawal S,Kumar S,Prasad N

更新日期：2015-01-01 00:00:00

abstract：:From July 1984 to December 1987, 9 patients with lupus nephritis did not respond to the administration of two courses of methylprednisolone pulse therapy and cyclophosphamide treatment for 56 days. Therefore, high-dose intravenous human gamma-globulin (IVIG) was administrated. Before IVIG therapy, renal biopsy showed ...

journal_title：Nephron

authors： Lin CY,Hsu HC,Chiang H

更新日期：1989-01-01 00:00:00

abstract：:Renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (RBF), glomerular filtration rate (GFR), sodium excretion (UNaV), and intrarenal distribution of blood ...

journal_title：Nephron

authors： Katz MA,Shear L

更新日期：1975-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:Hematuria and proteinuria in rheumatoid arthritis (RA) are commonly associated with drug therapy but occur independently of drugs, amyloid or urologic disorders. The latter occurrences suggest a primary renal lesion associated with RA. Review of reported renal biopsies identifies mesangial glomerulopathy as a common f...

journal_title：Nephron

authors： Pollet S,Depner T,Moore P,Olander H,Robbins D

更新日期：1989-01-01 00:00:00

abstract：:Six cases of perimembranous-type renal amyloidosis were reported. This type of renal amyloidosis was characterized by amyloid deposition predominantly involving the epithelial aspect of the glomerular capillary wall. Florid spicular arrangement was another representative feature. This type of amyloid deposition was fo...

journal_title：Nephron

authors： Shiiki H,Shimokama T,Yoshikawa Y,Onoyama K,Morimatsu M,Watanabe T

更新日期：1989-01-01 00:00:00

abstract：:The authors report on the presence of anti-HCV antibodies in a uremic chronic (UC) patient population after 6 months and 1 year with regard to certain selective preventive measures. The nonincreased number of HCV-positive subjects among the UC population could lead to the conclusion that the risk of environmental spre...

journal_title：Nephron

authors： Di Benedetto A,Bilotta E,Minale S,Tritto MC,Russo Spena S,Picardi E,Sorice P

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND/AIMS:Genetic cell ablation using the human diphtheria toxin receptor (hDTR) is a new strategy used for analysing cellular function. Diphtheria toxin (DT) is a cytotoxic protein that leaves mouse cells relatively unaffected, but upon binding to hDTR it ultimately leads to cell death. We used a podocyte-specif...

journal_title：Nephron

authors： Stevens M,Neal CR,Salmon AHJ,Bates DO,Harper SJ,Oltean S

更新日期：2018-01-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-...

journal_title：Nephron

authors： Elias AN,Vaziri ND,Pandian MR,Powers DR,Domurat E

更新日期：1988-01-01 00:00:00

abstract：:We encountered 11 patients with aluminum-associated bone disease (AABD), and treated them with deferoxamine (DFO). In 3 patients, a second bone biopsy was done during DFO treatment. Clinical features of AABD were compared with surgically proven secondary hyperparathyroidism (2 degrees HPT) with osteitis fibrosa on X-r...

journal_title：Nephron

authors： Iwamoto N,Ono T,Yamazaki S,Fukuda T,Kondo M,Yamamoto N,Hiratake Y,Masugi Y,Kubo Y,Hino M

更新日期：1986-01-01 00:00:00

abstract：:A 5-year-old Japanese boy showed nephritis similar to, but distinct from, that in Alport syndrome. Nephrotic syndrome without hematuria was noticed at age 2, although renal biopsy at age 4 revealed widespread irregular thickening of the glomerular basement membrane with splitting of the lamina densa on electron micros...

journal_title：Nephron

authors： Kawakami H,Murakami T,Murano I,Ushijima T,Taguchi T,Hattori S,Kajii T

更新日期：1990-01-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Complete remission (CR) and partial remission (PR) are beneficial to the long-term outcome of patients with idiopathic membranous nephropathy (iMN). However, we are lacking in studies that evaluate the clinical predictors of response to treatment with prednisone plus cyclophosphamide (CP). The objectives of ...

journal_title：Nephron

authors： Li S,Wang L,Zhang M,Zhou W,Fang W,Wang Q,Qi C,Mou S,Shao X,Ni Z

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Pruritus is one of the most common and disturbing symptoms in hemodialysis (HD) patients. The pathogenesis of pruritus in HD patients is multifactorial; however, a little progress in understanding this pathogenesis has been achieved. OBJECTIVES:To evaluate the frequency and risk factors of pruritus among HD...

journal_title：Nephron

authors： Abdelsalam M,Tawfik M,Reda EM,Eldeeb AA,Abdelwahab A,Zaki ME,Abdelkader Sobh M

更新日期：2019-01-01 00:00:00

abstract：:Survival after serum creatinine exceeded 10.0 mg/100 ml was increased if one peritoneal dialysis was performed. After one peritoneal dialysis 'survival' of 62 patients to the present time, death or the next dialysis averaged 119 days; median survival was 28 days. Characteristics of prolonged survivors were persisten...

journal_title：Nephron

authors： Maher JF,Ahearn DJ,Bryan CW,Nolph KD

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：:The effect of dilazep, an adenosine potentiator and platelet aggregation inhibitor, on experimental diabetic nephropathy was investigated in spontaneous diabetic Chinese hamster. Prediabetic animals, 8 weeks of age, were divided into two groups. In one group, 5 mg/kg dilazep was injected i.p. once a day. In the other ...

journal_title：Nephron

authors： Morikawa A,Eto M,Makino I

更新日期：1993-01-01 00:00:00

abstract：:The purpose of this study was to characterize renal cell carcinoma tissue by the measurement of microacoustic properties. A scanning acoustic microscope system operating in the frequency range of 100-200 MHz was employed and the attenuation constant and sound speed were measured on the two-dimensional distribution. Th...

journal_title：Nephron

authors： Sasaki H,Tanaka M,Saijo Y,Okawai H,Terasawa Y,Nitta S,Suzuki K

更新日期：1996-01-01 00:00:00

abstract：:We describe a case of nephrotic syndrome (idiopathic membranous glomerulonephropathy) with high serum HDL cholesterol (91 mg/100 ml) which increased to 240 mg/100 ml following steroid therapy. The increase in HDL was mainly a result of increased HDL2 and increased plasma apolipoprotein A-I. ...

journal_title：Nephron

authors： Sasaki J,Hara F,Motooka T,Naito S,Arakawa K

更新日期：1985-01-01 00:00:00

abstract：:Diffuse crescentic glomerulonephritis was observed in a 40-year-old male patient who had a ventriculoatrial shunt implanted after a traffic accident 10 years previously. Immediately after treatment with immunosuppressants and plasma pheresis, signs of meningitis and septicemia developed. The responsible organism isola...

journal_title：Nephron

authors： Wakabayashi Y,Kobayashi Y,Shigematsu H

更新日期：1985-01-01 00:00:00

abstract：:The effects of chitosan-coated dialdehyde cellulose (chitosan DAC), a newly developed oral adsorbent for urea and ammonia, were examined in a glomerulonephritis model in rats. Mesangial proliferative glomerulonephritis accompanied with proteinuria was induced by an intravenous injection of anti-rat Thy-1.1 monoclonal ...

journal_title：Nephron

authors： Yagi M,Kato S,Nishitoba T,Sato H,Kobayashi N,Iinuma N,Nagano N

更新日期：1998-01-01 00:00:00

abstract：:In order to evaluate effects of metabolic acidosis on glucose metabolism in uremia, we studied, by an intravenous glucose tolerance test (IVGTT), 46 patients with severe chronic renal failure divided into three groups according to their blood bicarbonate (BB) values: group A formed by 15 patients without or with light...

journal_title：Nephron

authors： Allegra V,Mengozzi G,Martimbianco L,Vasile A

更新日期：1993-01-01 00:00:00

abstract：:5 cases of severe acute renal failure caused by ethyl alcohol-induced rhabdomyolysis are reviewed. 4 patients were dialyzed. All patients recovered completely from the renal failure. ...

journal_title：Nephron

authors： Haapanen E,Pellinen TJ,Partanen J

更新日期：1984-01-01 00:00:00

abstract：:Dialysate effluent protein content was measured in 22 patients undergoing continuous ambulatory peritoneal dialysis (9 with and 13 without previous peritonitis). The average amount of protein in those patients without peritonitis was 1.3 g/2 liters exchanged over a 6-hour period, while that of patients with previous p...

journal_title：Nephron

authors： Katirtzoglou A,Oreopoulos DG,Husdan H,Leung M,Ogilvie R,Dombros N

更新日期：1980-01-01 00:00:00